Human Genome Sequencing and After

            Human Genome Sequencing is complete – announcement was made by the leaders of a Public Consortium of academic centres at the National Institutes of Health in April, 2003. The project initiated in 1990 was expected to take 15 yrs. It has been completed two years ahead of schedule, thanks to automation and bioinformatics. The announcement was timed to coincide with the 50th anniversary of the discovery of the structure of DNA by Watson and Crick. The unfolding of human genome with about 3 billion base pairs arrayed in 23 chromosomes costing about $800 million, is exciting enough to push biology into Biotechnology with great expectations in diagnostics, vaccines, new drugs, gene therapy and cloning. It is interesting to note that only less than 5% of DNA with 30000 genes codes for proteins. More than 95% of DNA is non coding and possibly involved in regulation of gene expression during development, differentiation and adaptation to environment.  All humans have the same DNA to the extent of 99.9 percent, the 0.1% making the difference between the female and male, young and old, intelligent and dullard, aggressive and mild, normal and disabled thus emphasising the  importance of understanding of DNA organization, regulation of expression, suppression and environmental adaptation. Comparative Genomics have shown that humans share 98% of their genetic sequence with monkeys and 57% with cabbage. The humble weed plant, Thale cross (Arabidopsis thaliana) has 30% of genes with notable similarities to humans. A long and difficult path is ahead.  The genetic polymorphism, function of non coding DNA, regulation by biomolecules, proteomics are the challenging areas in the coming years to understand the nature and explain growth, differentiation, behavior and environmental adaptation.  


July 1, 2023                                    Dr. B.  C.  Harinath




Future event at JBTDRC


Workshop on “Medical Informatics & Biomedical Communication”

(Sponsored by Department of Biotechnology and in collaboration with ICMR)

September 29 – October 1, 2023

For exposing Medical Teachers, Scientists & Postgraduate Students to the advancements in Bioinformatics, the Medical Informatics and Awareness & Utilization of Biomedical Communication Skills. Interesting Lectures, Demonstrations & Hands on Sessions will be conducted by the Eminent Experts in Bioinformatics.

· Last Date:  August 15, 2003
Selection confirmation by
: September 1, 2023 
  Registration Fee:
Rs. 500/-  
· Accommodation Charges: Rs. 150/- for 3 days


Click below for

 Workshop Brochure 

 Registration form 


Dr. Satish Kumar, Officer-in-charge, Bioinformatics Centre, JB Tropical Disease Research Centre, Mahatma Gandhi Institute of Medical Sciences, Sevagram  (Wardha) – 442 102.