|
Table 1: Comparative analysis of antibody detection by SEVA TB ELISA (IgG)
and circulating free & immune complexed antigen by SEVA TB ELISA (Ag)
in pulmonary tuberculosis (Banerjee et
al Indian Journal of Clin Biochem, 2001).
|
|
Group
|
Total
no. screened
|
No. (%) showing +ve reaction
for
|
|
Ab*
Ag**
CIC-Ag**
|
|
Pulmonary
Tb (S+C+)
|
25
|
23
(92)
|
20
(80)
|
18
(72)
|
|
Disease
Controls
|
18
|
1
(5.5)
|
1
(5.5)
|
1
(5.5)
|
|
COAD
|
6
|
1
|
-
|
-
|
|
Leprosy
|
4
|
-
|
-
|
-
|
|
Chronic
bronchitis
|
4
|
-
|
1
|
1
|
|
Pneumonia
|
4
|
-
|
-
|
-
|
Healthy Controls
|
20
|
1
(5)
|
1
(5)
|
-
|
|
|
*Sera
showing positive reaction at 1:600 dilution
**Sera showing positive reaction at 1:300 dilution
|
|
Table 2: SEVA TB IgG ELISA for detecting antibody in extra pulmonary
tuberculosis (Banerjee et al in
communication).
|
|
Group
|
Total
No. Screened
|
No.
(%) positivity for tubercular IgG antibody* to ES – 31/ 41
|
|
Tubercular lymphadenopathy
|
25
|
22
(88)
|
|
Tubercular meningitis
|
10
|
9
(90)
|
|
Abdominal tuberculosis
|
27
|
22
(81.5)
|
|
Bone & Joint
tuberculosis
|
26
|
22
(84.6)
|
Disease Controls
|
|
|
|
Non-Specific. lymphadenitis
|
7
|
1
|
|
Pyogenic meningitis
|
5
|
1
|
|
Ulcerative colitis
|
4
|
-
|
|
Crohn’s disease
|
4
|
-
|
|
Rheumatoid arthritis
|
8
|
1
|
Healthy Controls
|
20
|
2
(10)
|
|
|
*
Sera showing positive reaction at 1: 600 dilution
*ES-41 was used for IgG detection in bone & joint and abdominal TB
cases
|
|
Table 3: Six month follow up of pulmonary tuberculosis patients during
ATT for circulating tubercular antigen by SEVA TB (Ag) ELISA (Pati et
al in communication)
|
|
Day
of sample collection
|
No.
screened
|
No.
(%) showing positive reaction for*
Antigen
by SEVA TB ELISA (Ag)
|
|
0
|
32
|
18
(56)
|
|
30
|
32
|
17
(53)
|
|
60
|
32
|
16
(50)
|
|
180
|
32
|
8 (25)
|
|
| *Sera
showing positive reaction at 1:100 dilution. |