1.       Bhaskar A, Pradhan P, Chaturvedi P, Basak A, Lodam A, Narang P and Harinath BC: Immunodiagnosis of childhood pulmonary and extra pulmonary tuberculosis using Mycobacterium tuberculosis ES antigen by penicillinase ELISA. Annals of Tropical Paediatrics.  (1994);14:25-30.

2.       Nair ER, Kumar S, Reddy MVR and Harinath BC: Mycobacterium tuberculosis H37Ra ESAS-7. An excretory-secretory antigen fraction of immunodiagnostic potential in pulmonary tuberculosis. Indian J Clin Biochem. (1998);13 (2):98-105.

3.       Nair ER, Banerjee Swati, Kumar Satish & Harinath BC: Isolation and characterisation of a 31 kDa Mycobacterial antigen from tuberculous sera and its identification with in vitro released culture filtrate antigen of M.tb H37Ra bacilli. Scand J Infect Dis (2000);32:551-556.

4.       Nair ER., Banerjee Swati, Kumar Satish, Reddy MVR & Harinath BC; Purification and Characterization of a 31 kDa mycobacterial excretory-secretory antigenic protein with a diagnostic potential in pulmonary tuberculosis. Indian J Chest Dis Allied Sci (2001); 43:81-90.

5.       Banerjee Swati, Gupta S, Kumar  Satish, Reddy MVR & Harinath BC: Seroreactivity of 31 kDa and 41 kDa mycobacterial secretary protein isolated from culture filtrate in extra pulmonary tuberculosis. (In communication).

6.       Banerjee Swati, Nair E Raji, Kumar Satish, Reddy MVR & Harinath BC: Assay of tubercular antibody, circulating free and immune complexed antigen in the diagnosis of pulmonary tuberculosis. Indian J Clin Biochem. (2001);16 (2):39-42.


For more information write to

 Director Professor & Head
JB Tropical Disease Research Centre & Dept. of Biochemistry
Mahatma Gandhi Institute of Medical Sciences
Sevagram – 442 102
 Telefax: 7152 – 84038
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Advantages of seva tb elisa

  •  The test can be done in simple hospital setting

  •  Helpful in childhood tuberculosis where sputum sample is difficult to obtain

  • Helpful in clinically suspected tuberculosis cases negative by routine diagnostic methods  like AFB  ear & culture examination.

  •  Useful in confirming tubercular aetiology in extrapulmonary tuberculosis viz; tubercular        lymphadenopathy, meninges-CNS tuberculosis, genito-urinary tuberculosis, bone & joint        tuberculosis, abdominal tuberculosis etc.

  •  Useful in immunomonitoring for confirming elimination of infection and patient’s       compliance in  tuberculosis cases during antituberculosis therapy

  • Preferred over the insensitive, cumbersome or time consuming & widely unavailable,        invasive &  expensive tests such as Bacteriological, Radiological, FNAC, Laproscopic    biopsy, USG, CT,    Radionucleide bone scan, DNA probes, PCR etc.