Diagnosis, Diagnostics, Immunodiagnosis & Immunodiagnostics:

7808.      Adams BK, Cydulka RK.  Asthma evaluation and management. Emerg Med Clin North Am. 2003 May;21(2):315-30.

7809.      Addington WR, Stephens RE, Widdicombe JG, Anderson JW, Rekab K.  Effect of tartaric acid-induced cough on pulmonary function in normal and asthmatic humans. Am J Phys Med Rehabil. 2003 May;82(5):374-8.

7810.      Anees W.  Use of pulmonary function tests in the diagnosis of occupational asthma. Ann Allergy Asthma Immunol. 2003 May;90(5 Suppl 2):47-51.

7811.      Arets HG, Brackel HJ, van der Ent CK.  Applicability of interrupter resistance measurements using the MicroRint in daily practice. Respir Med. 2003 Apr;97(4):366-74.

7812.      Baraldi E, Carraro S, Alinovi R, Pesci A, Ghiro L, Bodini A, Piacentini G, Zacchello F, Zanconato S.  Cysteinyl leukotrienes and 8-isoprostane in exhaled breath condensate of children with asthma exacerbations. Thorax. 2003 Jun;58(6):505-9.

7813.      Barczyk A, Pierzchala W, Sozanska E.  Interleukin-17 in sputum correlates with airway hyperresponsiveness to methacholine. Respir Med. 2003 Jun;97(6):726-33.

7814.      Benayoun L, Druilhe A, Dombret MC, Aubier M, Pretolani M.  Airway structural alterations selectively associated with severe asthma. Am J Respir Crit Care Med. 2003 May 15;167(10):1360-8. Epub 2003 Jan 16.

7815.      Currie GP, Lee DK, Lipworth BJ.  Asthma exacerbations and sputum eosinophil counts. Lancet. 2003 Apr 12;361(9365):1302-3;

7816.      Davies PD.  The challenge of tuberculosis. J R Soc Med. 2003 Jun;96(6):262-5.

7817.      Di Franco A, Bartoli ML, Carnevali S, Cianchetti S, Bacci E, Dente FL, Giannini D, Taccola M, Vagaggini B, Paggiaro PL.  Analysis of sputum cell counts during spontaneous moderate exacerbations of asthma in comparison to the stable phase. J Asthma. 2003 Apr;40(2):155-62.

7818.      Erpenbeck VJ, Hohlfeld JM, Volkmann B, Hagenberg A, Geldmacher H, Braun A, Krug N.  Segmental allergen challenge in patients with atopic asthma leads to increased IL-9 expression in bronchoalveolar lavage fluid lymphocytes. J Allergy Clin Immunol. 2003 Jun;111(6):1319-27.

7819.      Han Z, Junxu, Zhong N.  Expression of matrix metalloproteinases MMP-9 within the airways in asthma. Respir Med. 2003 May;97(5):563-7.

7820.      Huang J, Jiang Y.  Genetic linkage analysis of a dichotomous trait incorporating a tightly linked quantitative trait in affected sib pairs. Am J Hum Genet. 2003 Apr;72(4):949-60. Epub 2003 Mar 17.

7821.      Kapui Z, Varga M, Urban-Szabo K, Mikus E, Szabo T, Szeredi J, Batori S, Finance O, Aranyi P.  Biochemical and pharmacological characterization of 2-(9-(2-piperidinoethoxy)-4-oxo-4H-pyrido[1,2-a]pyrimidin-2-yloxymethyl)-4-(1-me thylethyl)-6-methoxy-1,2-benzisothiazol-3(2H)-one-1,1-dioxide (SSR69071), a novel, orally active elastase inhibitor. J Pharmacol Exp Ther. 2003 May;305(2):451-9. Epub 2003 Feb 11.

7822.      Lee IS.  Effect of bedding control on amount of house dust mite allergens, asthma symptoms, and peak expiratory flow rate. Yonsei Med J. 2003 Apr 30;44(2):313-22.

7823.      Lewis CA, Eaton TE, Fergusson W, Whyte KF, Garrett JE, Kolbe J.  Home overnight pulse oximetry in patients with COPD: more than one recording may be needed. Chest. 2003 Apr;123(4):1127-33.

7824.      Lieutier-Colas F, Purohit A, Meyer P, Fabries JF, Kopferschmitt MC, Dessanges JF, Pauli G, de Blay F.  Bronchial challenge tests in patients with asthma sensitized to cats: the importance of large particles in the immediate response. Am J Respir Crit Care Med. 2003 Apr 15;167(8):1077-82.

7825.      Mortimer KM, Fallot A, Balmes JR, Tager IB.  Evaluating the use of a portable spirometer in a study of pediatric asthma. Chest. 2003 Jun;123(6):1899-907.

7826.      Ortega AN, McQuaid EL, Canino G, Ramirez R, Fritz GK, Klein RB.  Association of psychiatric disorders and different indicators of asthma in island Puerto Rican children. Soc Psychiatry Psychiatr Epidemiol. 2003 Apr;38(4):220-6.

7827.      Ownby DR.  Strategies for distinguishing asymptomatic latex sensitization from trueoccupational allergy or asthma. Ann Allergy Asthma Immunol. 2003 May;90(5 Suppl 2):42-6.

7828.      Pajukanta P, Allayee H, Krass KL, Kuraishy A, Soro A, Lilja HE, Mar R, Taskinen MR, Nuotio I, Laakso M, Rotter JI, de Bruin TW, Cantor RM, Lusis AJ, Peltonen L.  Combined analysis of genome scans of dutch and finnish families reveals a susceptibility locus for high-density lipoprotein cholesterol on chromosome 16q. Am J Hum Genet. 2003 Apr;72(4):903-17. Epub 2003 Mar 12.

7829.      Persson T, Monsef N, Andersson P, Bjartell A, Malm J, Calafat J, Egesten A.  Expression of the neutrophil-activating CXC chemokine ENA-78/CXCL5 by human eosinophils. Clin Exp Allergy. 2003 Apr;33(4):531-7.

7830.      Peterson MW.  Accessing the tools for improved asthma management. Am J Med. 2003 Apr 1;114(5):415-6.

7831.      Samee S, Altes T, Powers P, de Lange EE, Knight-Scott J, Rakes G, Mugler JP 3rd, Ciambotti JM, Alford BA, Brookeman JR, Platts-Mills TA. Imaging the lungs in asthmatic patients by using hyperpolarized helium-3 magnetic resonance: assessment of response to methacholine and exercise challenge. J Allergy Clin Immunol. 2003 Jun;111(6):1205-11.

7832.      Saotome A, Kanai N, Nagai T, Yashiro T, Tokudome S.  Immunohistochemical classification of the localization of laminin in the thickened bronchial epithelial basement membrane of deceased bronchial asthma patients. Respir Med. 2003 Jun;97(6):688-94.

7833.      Stoloff SW, Stempel DA.  Study design is a major determinant of whether equivalence or superiority is demonstrated. J Allergy Clin Immunol. 2003 Jun;111(6):1413;

7834.      Tarlo SM, Liss GM.  Occupational asthma: an approach to diagnosis and management. CMAJ. 2003 Apr 1;168(7):867-71. Review. No abstract available. Erratum in: CMAJ. 2003 Apr 15;168(8):966.

7835.      Tarlo SM.  Laboratory challenge testing for occupational asthma. J Allergy Clin Immunol. 2003 Apr;111(4):692-4.

7836.      Taube C, Kanniess F, Gronke L, Richter K, Mucke M, Paasch K, Eichler G, Jorres RA, Magnussen H.  Reproducibility of forced inspiratory and expiratory volumes after bronchodilation in patients with COPD or asthma. Respir Med. 2003 May;97(5):568-77.

7837.      Taussig LM, Wright AL, Holberg CJ, Halonen M, Morgan WJ, Martinez FD.  Tucson Children's Respiratory Study: 1980 to present. J Allergy Clin Immunol. 2003 Apr;111(4):661-75; quiz 676.

7838.      Vrijhoef HJ, Diederiks JP, Wesseling GJ, van Schayck CP, Spreeuwenberg C.  Undiagnosed patients and patients at risk for COPD in primary health care: early detection with the support of non-physicians. J Clin Nurs. 2003 May;12(3):366-73.

7839.      Wagers S.  Polarized helium: changing our view of asthma. J Allergy Clin Immunol. 2003 Jun;111(6):1201-2.

7840.      Warner JO.  The blood lung function test: does it exist for asthma? Am J Respir Crit Care Med. 2003 Jun 1;167(11):1465-6.

7841.      Yao TC, Kuo ML, See LC, Chen LC, Yan DC, Ou LS, Shaw CK, Huang JL. The RANTES promoter polymorphism: a genetic risk factor for near-fatal asthma in Chinese children. J Allergy Clin Immunol. 2003 Jun;111(6):1285-92. 

7842.      Zaitsu M, Hamasaki Y, Matsuo M, Ichimaru T, Fujita I, Ishii E.  Leukotriene synthesis is increased by transcriptional up-regulation of  5-lipoxygenase, leukotriene A4 hydrolase, and leukotriene C4 synthase in asthmatic children. J Asthma. 2003 Apr;40(2):147-54.

Pathogenesis:

7843.      Colilla S, Nicolae D, Pluzhnikov A, Blumenthal MN, Beaty TH, Bleecker ER, Lange EM, Rich SS, Meyers DA, Ober C, Cox NJ; Collaborative Study for the Genetics of Asthma.   Evidence for gene-environment interactions in a linkage study of asthma and smoking exposure. J Allergy Clin Immunol. 2003 Apr;111(4):840-6.

7844.      Donninger H, Glashoff R, Haitchi HM, Syce JA, Ghildyal R, van Rensburg E, Bardin PG.  Rhinovirus induction of the CXC chemokine epithelial-neutrophil activating peptide-78 in bronchial epithelium. J Infect Dis. 2003 Jun 1;187(11):1809-17.

7845.      Elias JA, Lee CG, Zheng T, Shim Y, Zhu Z.  Interleukin-13 and leukotrienes: an intersection of pathogenetic schema. Am J Respir Cell Mol Biol. 2003 Apr;28(4):401-4.

7846.      Kabesch M, Peters W, Carr D, Leupold W, Weiland SK, von Mutius E.  Association between polymorphisms in caspase recruitment domain containing protein 15 and allergy in two German populations. J Allergy Clin Immunol. 2003 Apr;111(4):813-7.

7847.      Kelly-Welch AE, Hanson EM, Boothby MR, Keegan AD.  Interleukin-4 and interleukin-13 signaling connections maps. Science. 2003 Jun 6;300(5625):1527-8.

7848.      Lopuhaa CE, de Riemer MJ, Out TA, Sjamsoedin DH, Aalberse RC, Jansen HM, van der Zee JS.  Comparison of allergen-induced late inflammatory reactions in the nose and in the skin in house dust mite-allergic patients with or without asthma. Int Arch Allergy Immunol. 2003 Apr;130(4):266-74.

7849.      Obase Y, Shimoda T, Kawano T, Saeki S, Tomari SY, Mitsuta-Izaki K, Matsuse H, Kinoshita M, Kohno S.  Polymorphisms in the CYP1A2 gene and theophylline metabolism in patients with asthma. Clin Pharmacol Ther. 2003 May;73(5):468-74.

7850.      Pierzchalska M, Szabo Z, Sanak M, Soja J, Szczeklik A.  Deficient prostaglandin E2 production by bronchial fibroblasts of asthmatic patients, with special reference to aspirin-induced asthma. J Allergy Clin Immunol. 2003 May;111(5):1041-8.

7851.      Reibman J, Hsu Y, Chen LC, Bleck B, Gordon T.  Airway epithelial cells release MIP-3alpha/CCL20 in response to cytokines and ambient particulate matter. Am J Respir Cell Mol Biol. 2003 Jun;28(6):648-54.

7852.      Silverman ES, Drazen JM.  Immunostimulatory DNA for asthma: better than eating dirt. Am J Respir Cell Mol Biol. 2003 Jun;28(6):645-7.

7853.      Taha R, Hamid Q, Cameron L, Olivenstein R.  T helper type 2 cytokine receptors and associated transcription factors GATA-3, c-MAF, and signal transducer and activator of transcription factor-6 in induced sputum of atopic asthmatic patients. Chest. 2003 Jun;123(6):2074-82.

7854.      Tamura K, Suzuki M, Arakawa H, Tokuyama K, Morikawa A.  Linkage and association studies of STAT6 gene polymorphisms and allergic diseases. Int Arch Allergy Immunol. 2003 May;131(1):33-8.

Therapy:

7855.      Menzies-Gow A, Flood-Page P, Sehmi R, Burman J, Hamid Q, Robinson DS, Kay AB, Denburg J.  Anti-IL-5 (mepolizumab) therapy induces bone marrow eosinophil maturational arrest and decreases eosinophil progenitors in the bronchial mucosa of atopic asthmatics. J Allergy Clin Immunol. 2003 Apr;111(4):714-9.

7856.      Selroos O, Ekstrom T, Hultquist C.  The EDICT study. Respir Med. 2003 Apr;97(4):446;

7857.      van Strien RT, Koopman LP, Kerkhof M, Oldenwening M, de Jongste JC, Gerritsen J, Neijens HJ, Aalberse RC, Smit HA, Brunekreef B; Prevention and Incidence of Asthma and Mite Allergy Study.   Mattress encasings and mite allergen levels in the Prevention and Incidence of Asthma and Mite Allergy study. Clin Exp Allergy. 2003 Apr;33(4):490-5.