ALLERGY

   January 2005

   Diagnosis, Diagnostics, Immunodiagnosis & Immunodiagnostics:

10825.   Abubakar I, Leonardi GS, Edwards N, Herriott N. Inter-rater agreement in defining chemical incidents at the National Poisons Information Service, London.J Epidemiol Community Health. 2004 Aug;58(8):718-22.

10826.   Baines P, Carrol ED. Recombinant tissue plasminogen activator in children with meningococcal purpura fulminans--role uncertain. Crit Care Med. 2004 Aug;32(8):1806-7.

10827.   Blake SP, McNicholas MM. Hypersensitivity to intravenous contrast material causing CT appearance of bowel wall thickening. Clin Radiol. 2004 Jul;59(7):638-40. 

10828.   Bucchioni E, Csoma Z, Allegra L, Chung KF, Barnes PJ, Kharitonov SA. Adenosine 5'-monophosphate increases levels of leukotrienes in breath condensate in asthma. Respir Med. 2004 Jul;98(7):651-5.

10829.   Bunder R, Mittermann I, Herz U, Focke M, Wegmann M, Valenta R, Renz H. Induction of autoallergy with an environmental allergen mimicking a self protein in a murine model of experimental allergic asthma. J Allergy Clin Immunol. 2004 Aug;114(2):422-8.

10830.   Cole Johnson C, Ownby DR, Havstad SL, Peterson EL. Family history, dust mite exposure in early childhood, and risk for pediatric atopy and asthma. J Allergy Clin Immunol. 2004 Jul;114(1):105-10.

10831.   Crummy F, Livingston M, Ennis M, Heaney LG. Mast cell mediator release in nonasthmatic subjects after endobronchial adenosine challenge. J Allergy Clin Immunol. 2004 Jul;114(1):34-9.

10832.   Dillon SR, Sprecher C, Hammond A, Bilsborough J, Rosenfeld-Franklin M, Presnell SR, Haugen HS, Maurer M, Harder B, Johnston J, Bort S, Mudri S, Kuijper JL, Bukowski T, Shea P, Dong DL, Dasovich M, Grant FJ, Lockwood L, Levin SD, LeCiel C, Waggie K, Day H, Topouzis S, Kramer J, Kuestner R, Chen Z, Foster D, Parrish-Novak J, Gross JA. Interleukin 31, a cytokine produced by activated T cells, induces dermatitis in mice. Nat Immunol. 2004 Jul;5(7):752-60. 

10833.   Donnelly SE, Donnelly BJ, Saliken JC, Raber EL, Vellet AD. Prostate cancer: gadolinium-enhanced MR imaging at 3 weeks compared with needle biopsy at 6 months after cryoablation. Radiology. 2004 Sep;232(3):830-3. 

10834.   Guler N, Kirerleri E, Ones U, Tamay Z, Salmayenli N, Darendeliler F. Leptin: does it have any role in childhood asthma? J Allergy Clin Immunol. 2004 Aug;114(2):254-9.

10835.   Hamilton RG, Franklin Adkinson N Jr. In vitro assays for the diagnosis of IgE-mediated disorders. J Allergy Clin Immunol. 2004 Aug;114(2):213-25;

10836.   Harwanegg C, Hiller R. Protein microarrays in diagnosing IgE-mediated diseases: spotting allergy at the molecular level. Expert Rev Mol Diagn. 2004 Jul;4(4):539-48.

10837.   Kabesch M, Hoefler C, Carr D, Leupold W, Weiland SK, von Mutius E. Glutathione S transferase deficiency and passive smoking increase childhood asthma. Thorax. 2004 Jul;59(7):569-73.

10838.   Kawakita T, Takano Y, Asano-Kato N, Tanaka M, Dogru M, Goto E, Tsubota K, Takahashi S, Fukagawa K, Fujishima H. Quantitative evaluation of eyelid elasticity using the cutometer SEM575 and its clinical application in assessing the efficacy of tacrolimus ointment treatment in eyelid atopic dermatitis. Cornea. 2004 Jul;23(5):468-71.

10839.   Kim CK, Hagan JB. Sputum tests in the diagnosis and monitoring of asthma. Ann Allergy Asthma Immunol. 2004 Aug;93(2):112-22; quiz 122-4, 184.

10840.   Krouse JH, Shah AG, Kerswill K. Skin testing in predicting response to nasal provocation with alternaria. Laryngoscope. 2004 Aug;114(8):1389-93.

10841.   Marinella MA. Images in clinical medicine. Henoch-Schonlein purpura. N Engl J Med. 2004 Jul 15;351(3):278.

10842.   Mintz M. Asthma update: part I. Diagnosis, monitoring, and prevention of disease progression. Am Fam Physician. 2004 Sep 1;70(5):893-8.

10843.   Morris CR, Poljakovic M, Lavrisha L, Machado L, Kuypers FA, Morris SM Jr. Decreased arginine bioavailability and increased serum arginase activity in asthma. Am J Respir Crit Care Med. 2004 Jul 15;170(2):148-53.

10844.   Niimi A, Nguyen LT, Usmani O, Mann B, Chung KF. Reduced pH and chloride levels in exhaled breath condensate of patients with chronic cough.Thorax. 2004 Jul;59(7):608-12.

10845.   Perry TT, Matsui EC, Kay Conover-Walker M, Wood RA. The relationship of allergen-specific IgE levels and oral food challenge outcome. J Allergy Clin Immunol. 2004 Jul;114(1):144-9.

10846.   Phoa LL, Toelle BG, Ng K, Marks GB. Effects of gas and other fume emitting heaters on the development of asthma during childhood. Thorax. 2004 Sep;59(9):741-5.

10847.   Sharafkhaneh A, Officer TM, Goodnight-White S, Rodarte JR, Boriek AM. Novel method for measuring effects of gas compression on expiratory flow. Am J Physiol Regul Integr Comp Physiol. 2004 Aug;287(2):R479-84.

10848.   Shek LP, Soderstrom L, Ahlstedt S, Beyer K, Sampson HA. Determination of food specific IgE levels over time can predict the development of tolerance in cow's milk and hen's egg allergy. J Allergy Clin Immunol. 2004 Aug;114(2):387-91.

10849.   Volcheck GW. Clinical evaluation and management of drug hypersensitivity. Immunol Allergy Clin North Am. 2004 Aug;24(3):357-71,

10850.   Vonk JM, Boezen HM, Postma DS, Schouten JP, van Aalderen WM, Boersma ER. Perinatal risk factors for bronchial hyperresponsiveness and atopy after a follow-up of 20 years. J Allergy Clin Immunol. 2004 Aug;114(2):270-6.

10851.   Watson KM, Salisbury JR, Creamer D. Purpura fulminans -- a novel presentation of Churg Strauss syndrome. Clin Exp Dermatol. 2004 Jul;29(4):390-2.

Pathogenesis:

10852.   Eckinger P, Ratner E, Brock-Utne J. Latex allergy: oh, what a surprise! Another reason why all anesthesia equipment should be latex-free. Anesth Analg. 2004 Aug;99(2):629. 

10853.   Eigenmann PA, Haenggeli CA. Food colourings and preservatives--allergy and hyperactivity. Lancet. 2004 Sep 4;364(9437):823-4. 

10854.   Leung TF, Tang NL, Li CY, Lam CW, Wong GW, Fok TF. Association between TARC C-431T and atopy and asthma in children. J Allergy Clin Immunol. 2004 Jul;114(1):199-202.  

10855.   Long JA, Fogel-Petrovic M, Knight DA, Thompson PJ, Upham JW. Higher prostaglandin e2 production by dendritic cells from subjects with asthma compared with normal subjects. Am J Respir Crit Care Med. 2004 Sep 1;170(5):485-91.

10856.   Mak JC, Leung HC, Ho SP, Law BK, Lam WK, Tsang KW, Ip MS, Chan-Yeung M. Systemic oxidative and antioxidative status in Chinese patients with asthma. J Allergy Clin Immunol. 2004 Aug;114(2):260-4.

10857.   Moed H, Boorsma DM, Tensen CP, Flier J, Jonker MJ, Stoof TJ, von Blomberg BM, Bruynzeel DP, Scheper RJ, Rustemeyer T, Gibbs S. Increased CCL27-CCR10 expression in allergic contact dermatitis: implications for local skin memory.J Pathol. 2004 Sep;204(1):39-46.

10858.   Nagarkatti R, Kumar R, Sharma SK, Ghosh B. Association of IL4 gene polymorphisms with asthma in North Indians. Int Arch Allergy Immunol. 2004 Jul;134(3):206-12. 

10859.   Nomura A, Kodama T, Morishima Y, Ishii Y, Sakamoto T, Kimura T, Sekizawa K. Cysteinyl leukotrienes and collagen type I synthesis in asthma. J Allergy Clin Immunol. 2004 Jul;114(1):197-9. 

10860.   Proctor L, Renzulli B, Warren S, Brecher ME. Transfusion Medicine Illustrated. Monoclonal antibody-stimulated serum sickness. Transfusion. 2004 Jul;44(7):955. 

10861.   Shek LP, Soderstrom L, Ahlstedt S, Beyer K, Sampson HA. Determination of food specific IgE levels over time can predict the development of tolerance in cow's milk and hen's egg allergy. J Allergy Clin Immunol. 2004 Aug;114(2):387-91.

10862.   Silva CI, Colby TV, Muller NL. Asthma and associated conditions: high-resolution CT and pathologic findings. AJR Am J Roentgenol. 2004 Sep;183(3):817-24. 

10863.   Sinclair D, Peters SA. The predictive value of total serum IgE for a positive allergen specific IgE result. J Clin Pathol. 2004 Sep;57(9):956-9. 

10864.   Smith WB, Gillis D, Kette FE. Lupin: a new hidden food allergen. Med J Aust. 2004 Aug 16;181(4):219-20. 

10865.   Stojanov S, Weiss M, Lohse P, Belohradsky BH. A novel CIAS1 mutation and plasma/cerebrospinal fluid cytokine profile in a German patient with neonatal-onset multisystem inflammatory disease responsive to methotrexate therapy. Pediatrics. 2004 Jul;114(1):e124-7.

10866.   Tanabe S, Shibata R, Nishimura T. Hypoallergenic and T cell reactive analogue peptides of bovine serum albumin, the major beef allergen. Mol Immunol. 2004 Jul;41(9):885-90.

10867.   Tapia B, Padial A, Sanchez-Sabate E, Alvarez-Ferreira J, Morel E, Blanca M, Bellon T. Involvement of CCL27-CCR10 interactions in drug-induced cutaneous reactions. J Allergy Clin Immunol. 2004 Aug;114(2):335-40.

10868.   Wickelgren I. Immunotherapy. Can worms tame the immune system? Science. 2004 Jul 9;305(5681):170-1. 

10869.   Wickelgren I. Immunotherapy. Wielding worms at asthma and autoimmunity. Science. 2004 Jul 9;305(5681):171.  

10870.   Wilkinson TS, Potter-Perigo S, Tsoi C, Altman LC, Wight TN. Pro- and anti-inflammatory factors cooperate to control hyaluronan synthesis in lung fibroblasts. Am J Respir Cell Mol Biol. 2004 Jul;31(1):92-9. 

Therapy:

10871.   Bhatia A, Smith H, Trivedi M. A response to 'Angiotensin-converting enzyme inhibitor related angioedema and the anaesthetist', Rai M R, Amen F and Idrees F, Anaesthesia 2004; 59: 283-9. Anaesthesia. 2004 Jul;59(7):732; author reply 732-3.   

10872.   de Asis ML, Greene R. A cost-effectiveness analysis of a peak flow-based asthma education and self-management plan in a high-cost population. J Asthma. 2004 Aug;41(5):559-65.   

10873.   Garcia Algar O, Pichini S, Basagana X, Puig C, Vall O, Torrent M, Harris J, Sunyer J, Cullinan P; AMICS group. Concentrations and determinants of NO2 in homes of Ashford, UK and Barcelona and Menorca, Spain. Indoor Air. 2004 Aug;14(4):298-304.   

10874.   Kemp A, Kakakios A. Asthma prevention: breast is best? J Paediatr Child Health. 2004 Jul;40(7):337-9. 

10875.   Lee DK. Urinary leukotriene LTE4 levels in non-responders to antileukotriene therapy. Thorax. 2004 Aug;59(8):727; author reply 727.   

10876.   Mahi-Taright S, Belhocine M, Ait-Khaled N. Can we improve the management of chronic obstructive respiratory disease? The example of asthma in adults. Int J Tuberc Lung Dis. 2004 Jul;8(7):873-81.

10877.   Rowinsky EK, Schwartz GH, Gollob JA, Thompson JA, Vogelzang NJ, Figlin R, Bukowski R, Haas N, Lockbaum P, Li YP, Arends R, Foon KA, Schwab G, Dutcher J.  Safety, pharmacokinetics, and activity of ABX-EGF, a fully human anti-epidermal growth factor receptor monoclonal antibody in patients with metastatic renal cell cancer. J Clin Oncol. 2004 Aug 1;22(15):3003-15. 

10878.   van der Wouden JC, Bueving HJ. Comment: safety and efficacy of influenza vaccine in children. Ann Pharmacother. 2004 Jul-Aug; 38(7-8):1323-4;  

10879.   Warsi A, Wang PS, LaValley MP, Avorn J, Solomon DH. Self-management education programs in chronic disease: a systematic review and methodological critique of the literature. Arch Intern Med. 2004 Aug 9-23;164(15):1641-9.     

10880.   Wright RJ. Alternative modalities for asthma that reduce stress and modify mood states: evidence for underlyiing psychobiologic mechanisms Ann Allergy Asthma Immunol. 2004 Aug;93(2 Suppl 1):S18-23.  

10881. Yip E. Consideration of barrier protection and latex protein allergy in the evaluation of medical gloves. J Infus Nurs. 2004 Jul-Aug;27(4):227-31.

April 2005

Some Selected Abstracts:

1.

 Heytman M, Rainbird A. Use of alpha-agonists for management of anaphylaxis occurring under anaesthesia: case studies and review. Anaesthesia. 2004 Dec;59(12):1210-5.

Department of Anaesthesia, The Townsville Hospital, Douglas, QLD 4814, Australia.

Anaphylaxis is an uncommon but serious complication of anaesthesia. Most current guidelines for the management of anaphylaxis list only epinephrine as a vasopressor to use in the event of cardiovascular collapse. We present two cases of anaphylaxis under anaesthesia where return of spontaneous circulation was refractory to epinephrine, but occurred following the administration of the alpha-agonist metaraminol. Potential advantages and disadvantages of using epinephrine in this setting, the role of alpha-agonists and some potential mechanisms accounting for their role in successful management are reviewed.

2.

Peat JK, Mihrshahi S, Kemp AS, Marks GB, Tovey ER, Webb K, Mellis CM, Leeder SR. Three-year outcomes of dietary fatty acid modification and house dust mite reduction in the Childhood Asthma Prevention Study. J Allergy Clin Immunol. 2004 Oct;114(4):807-13.

Discipline of Paediatrics and Child Health, Children's Hospital at Westmead Clinical School, University of Sydney, Australia.

BACKGROUND: Two factors thought to influence the risk of asthma are the promoting effect of sensitization to house dust mites and the preventive effect of increased omega-3 fatty acids. Although house dust mite allergen avoidance has been used as a preventive strategy in several trials, the effect of omega-3 fatty acid supplementation in the primary prevention of asthma and allergic disease is not known. OBJECTIVE: To measure the effects of dietary supplementation with omega-3 fatty acids and house dust mite allergen avoidance in children with a family history of asthma. METHODS: A total of 616 children at high risk of asthma were enrolled antenatally in a randomized controlled trial, and 526 children remained in the trial at age 3 years. The outcomes were symptoms of allergic disease and allergen sensitization. RESULTS: There was a significant 10.0% (95% CI, 3.7-16.4) reduction in the prevalence of cough in atopic children in the active diet group ( P=.003; number needed to treat, 10) but a negligible 1.1% (95% CI, -7.1 to 9.5) reduction cough among nonatopic children. There was a 7.2% (95% CI, 10.11-14.3) reduction in sensitization to house dust mite in the active allergen avoidance group ( P=.05; number needed to treat, 14). No significant differences in wheeze were found with either intervention. CONCLUSION: These results suggest that our interventions, designed to be used in simple public health campaigns, may have a role in preventing the development of allergic sensitization and airways disease in early childhood. This offers the prospect of reducing allergic disease in later life.

3.

 Kalliomaki MA, Isolauri E. Probiotics and down-regulation of the allergic response. Immunol Allergy Clin North Am. 2004 Nov;24(4):739-52, viii. Review.

Combined Program in Pediatric Gastroenterology and Nutrition, Massachusetts General Hospital, Charlestown, MA 02129, USA. marko.kalliomaki@utu.fi

The first clinical trials with probiotics, especially in the treatment of atopic eczema, have yielded encouraging results. Experimental studies have found that probiotics exert strain-specific effects in the intestinal lumen and on epithelial cells and immune cells with anti-allergic potential. These effects include enhancement in antigen degradation and gut barrier function and induction of regulatory and proinflammatory immune responses, the latter of which occurs more likely beyond the intestinal epithelium. Future studies should address more accurately how these and other possible mechanisms operate in the complex gastrointestinal macroenvironment in vivo and how these mechanisms are related to the clinical effects in a dose-dependent manner.

4.

Kull I, Almqvist C, Lilja G, Pershagen G, Wickman M. Breast-feeding reduces the risk of asthma during the first 4 years of life. J Allergy Clin Immunol. 2004 Oct;114(4):755-60.

Department of Occupational and Environmental Health, Stockholm County Council, Sweden. inger.kull@sma.sll.se

BACKGROUND: The evidence for a preventive effect of breast-feeding on asthma and other allergic diseases in childhood is inconclusive. OBJECTIVE: The aim of this study was to investigate the effect of breast-feeding on asthma and sensitization to airborne allergens among children up to 4 years of age. METHODS: A birth cohort of 4089 children was followed. Exposure data were collected at 2 months and 1 year of age. The total dose of breast milk was estimated by combining periods of exclusive and partial breast-feeding. Outcomes data were collected at 1, 2, and 4 years of age. The response rate at 4 years was 90%, and 73% participated in a clinical investigation, including blood sampling for analysis of specific IgE and lung function testing. Children with onset of wheeze during lactation (n=217) were excluded in some of the analyses to avoid disease-related modification of exposure. RESULTS: Exclusive breast-feeding for 4 months or more reduced the risk of asthma at the age of 4 years (odds ratio [OR], 0.72; 95% CI, 0.53-0.97), irrespective of sensitization to common airborne allergens ( P=.72). Excluding children with wheeze during lactation tended to strengthen the risk estimate (OR, 0.64; 95% CI, 0.46-0.88). A duration of 3 months or more of partial breast-feeding seemed to offer additional protection; exclusive breast-feeding for 3 to 4 months combined with partial breast-feeding for 3 months or more resulted in an OR of 0.44 (95% CI, 0.21-0.87). The effects tended to be stronger in children without heredity for allergy ( P interaction=.36). CONCLUSION: Breast-feeding reduces the risk of asthma during the first 4 years of life.
Diagnosis, Diagnostics, Immunodiagnosis & Immunodiagnostics:

11277.    Allen-Ramey FC, Duong PT, Riedel AA, Markson LE, Weiss KB. Observational study of the effects of using montelukast vs fluticasone in patients matched at baseline. Ann Allergy Asthma Immunol. 2004 Oct;93(4):373-80.

11278.    Axon AD, Hunter JM. Editorial III: Anaphylaxis and anaesthesia--all clear now? Br J Anaesth. 2004 Oct;93(4):501-4. 

11279.     Bateman ED, Boushey HA, Bousquet J, Busse WW, Clark TJ, Pauwels RA, Pedersen SE; GOAL Investigators Group. Can guideline-defined asthma control be achieved? The Gaining Optimal Asthma ControL study. Am J Respir Crit Care Med. 2004 Oct 15;170(8):836-44.

11280.     Brooks DE, Graeme KA. Airway compromise after first rattlesnake envenomation. Wilderness Environ Med. 2004 Fall;15(3):188-93. Review.

11281.     Chavannes N, Schermer T, Akkermans R, Jacobs JE, van de Graaf G, Bollen R, van Schayck O, Bottema B. Impact of spirometry on GPs' diagnostic differentiation and decision-making. Respir Med. 2004 Nov;98(11):1124-30.

11282.     Dinakar C. Exhaled nitric oxide in the clinical management of asthma. Curr Allergy Asthma Rep. 2004 Nov;4(6):454-9. Review.

11283.     Fiocchi A, Besana R, Ryden AC, Terracciano L, Andreotti M, Arrigoni S, Martelli A. Differential diagnosis of IgE-mediated allergy in young children with wheezing or eczema symptoms using a single blood test. Ann Allergy Asthma Immunol. 2004 Oct;93(4):328-33.

11284.     Gelb AF, Schein A, Nussbaum E, Shinar CM, Aelony Y, Aharonian H, Zamel N. Risk factors for near-fatal asthma. Chest. 2004 Oct;126(4):1138-46.

11285.     Gomez R, Colas C, Sebastian A, Arribas J. Respiratory repercussions in adults with a history of infantile bronchiolitis. Ann Allergy Asthma Immunol. 2004 Nov;93(5):447-51.

11286.  Gupta PP, Gupta KB, Agarwal D, Sood S. Tropical pulmonary eosinophilia misdiagnosed as Miliary tuberculosis. Indian Journal of Allergy Asthma and Immunology. 2004 Jan-Jun; 18(1): 41-44.

11287.     Heytman M, Rainbird A. Use of alpha-agonists for management of anaphylaxis occurring under anaesthesia: case studies and review. Anaesthesia. 2004 Dec;59(12):1210-5.

11288.     Hiscock H, Jordan B. 1. Problem crying in infancy. Med J Aust. 2004 Nov 1;181(9):507-12. Review.

11289.     Kronander UN, Falkenberg M, Zetterstrom O. Prevalence and incidence of asthma related to waist circumference and BMI in a Swedish community sample. Respir Med. 2004 Nov;98(11):1108-16.

11290.     MacFaul R. Trends in asthma hospitalisation: is this related to prevention inhaler usage? Arch Dis Child. 2004 Dec;89(12):1158-60. 

11291.     McKeever TM, Britton J. Diet and asthma. Am J Respir Crit Care Med. 2004 Oct 1;170(7):725-9.   

11292.     Mehta SV, Parkin PC, Stephens D, Keogh KA, Schuh S. Oxygen saturation as a predictor of prolonged, frequent bronchodilator therapy in children with acute asthma. J Pediatr. 2004 Nov;145(5):641-5. Erratum in: J Pediatr. 2004 Dec;145(6):864.

11293.     Milgrom H. Anti-IgE therapy in children with asthma. Minerva Pediatr. 2004 Oct;56(5):469-79. Review.

11294.     Nayak NN, Shankar K. Yoga: a therapeutic approach. Phys Med Rehabil Clin N Am. 2004 Nov;15(4):783-98, vi. Review.

11295.     Payne DN, Qiu Y, Zhu J, Peachey L, Scallan M, Bush A, Jeffery PK. Airway inflammation in children with difficult asthma: relationships with airflow limitation and persistent symptoms. Thorax. 2004 Oct;59(10):862-9.

11296.     Peat JK, Mihrshahi S, Kemp AS, Marks GB, Tovey ER, Webb K, Mellis CM, Leeder SR. Three-year outcomes of dietary fatty acid modification and house dust mite reduction in the Childhood Asthma Prevention Study. J Allergy Clin Immunol. 2004 Oct;114(4):807-13.

11297.     Perry TT, Matsui EC, Conover-Walker MK, Wood RA. Risk of oral food challenges. J Allergy Clin Immunol. 2004 Nov;114(5):1164-8.

11298.    Rademaker M. Allergic contact dermatitis to a sanitary pad. Australas J Dermatol. 2004 Nov;45(4):234-5.

11299.     Redmond AM, James AW, Nolan SH, Self TH. Premenstrual asthma: emphasis on drug therapy options. J Asthma. 2004 Oct;41(7):687-93. Review.

11300.     Schaub B, von Mutius E. The marketing of asthma and allergies. Lancet. 2004 Oct 16;364(9443):1389-90. 

11301.     Sicherer SH, Teuber S; Adverse Reactions to Foods Committee. Current approach to the diagnosis and management of adverse reactions to foods. J Allergy Clin Immunol. 2004 Nov;114(5):1146-50. 

11302.     Simons FE, Peng Z. Early-onset cellulitis after insect bites: allergic inflammation. Ann Allergy Asthma Immunol. 2004 Dec;93(6):606; author reply 606-7. 

11303.     Smith H, White P, Annila I, Poole J, Andre C, Frew A. Randomized controlled trial of high-dose sublingual immunotherapy to treat seasonal allergic rhinitis. J Allergy Clin Immunol. 2004 Oct;114(4):831-7. 

11304.  Storms W, Chervinsky P, Ghannam AF, Bird S, Hustad CM, Edelman JM; Challenge-Rescue Study Group. A comparison of the effects of oral montelukast and inhaled salmeterol on response to rescue bronchodilation after challenge. Respir Med. 2004 Nov;98(11):1051-62.
Pathogenesis

11305.     Busse WW, Leung DY. New series: Perspectives in asthma. J Allergy Clin Immunol. 2004 Nov;114(5):1022.  

11306.     Cantorna MT, Zhu Y, Froicu M, Wittke A. Vitamin D status, 1,25-dihydroxyvitamin D3, and the immune system. Am J Clin Nutr. 2004 Dec;80(6  Suppl):1717S-20S. Review.

11307.     Chhabra SK. Does increased dietary salt intake worsen asthma? Indian J Chest Dis Allied Sci. 2004 Oct-Dec;46(4):247-9.

11308.     Cookson W, Moffatt M. Making sense of asthma genes. N Engl J Med. 2004 Oct 21;351(17):1794-6. 

11309.     Coppieters Y, Piette D. Targeting pupils at risk of occupational asthma. Patient Educ Couns. 2004 Oct; 55(1):136-41.

11310.   Goldrosen MH, Straus SE. Complementary and alternative medicine: assessing the evidence for immunological benefits. Nat Rev Immunol. 2004 Nov;4(11):912-21. Review.

11311.     Humphris CJ. Chemical danger. Lancet. 2004 Nov 27;364(9449):1937.

11312.     Isolauri E, Rautava S, Kalliomaki M. Food allergy in irritable bowel syndrome: new facts and old fallacies. Gut. 2004 Oct;53(10):1391-3.

11313.     Kalliomaki MA, Isolauri E. Probiotics and down-regulation of the allergic response. Immunol Allergy Clin North Am. 2004 Nov;24(4):739-52, viii. Review.

11314.     Kawano T, Matsuse H, Kondo Y, Machida I, Saeki S, Tomari S, Mitsuta K, Fukushima C, Obase Y, Shimoda T, Kohno S. Tacrolimus reduces urinary excretion of leukotriene E(4) and inhibits aspirin-induced asthma to threshold dose of aspirin. J Allergy Clin Immunol. 2004 Dec;114(6):1278-81.

11315.     Kollmeier AP, Eddleston J, Zuraw BL, Christiansen SC. Recurrent anaphylaxis linked to 1pantoprazole. J Allergy Clin Immunol. 2004 Oct;114(4):975-7.

11316.     Kull I, Almqvist C, Lilja G, Pershagen G, Wickman M. Breast-feeding reduces the risk of asthma during the first 4 years of life. J Allergy Clin Immunol. 2004 Oct;114(4):755-60.

11317.     Mendell MJ. Commentary: air conditioning as a risk for increased use of health services. Int J Epidemiol. 2004 Oct;33(5):1123-6. Epub 2004 Aug 19.

11318.     Moffitt JE. Reactions to insect bites and stings: what about the orphan insects? Ann Allergy Asthma Immunol. 2004 Dec;93(6):507-9.

11319.     Norman PS. Sublingual swallow immunotherapy in the new world.Ann Allergy Asthma Immunol. 2004 Nov;93(5):405-6.

11320.     O'Hagan DT, Rappuoli R. The safety of vaccines. Drug Discov Today. 2004 Oct 1;9(19):846-54. Review.

11321.     Openshaw PJ, Yamaguchi Y, Tregoning JS. Childhood infections, the developing immune system, and the origins of asthma. J Allergy Clin Immunol. 2004 Dec;114(6):1275-7.

11322.     Wal JM. Bovine milk allergenicity. Ann Allergy Asthma Immunol. 2004 Nov;93(5 Suppl 3):S2-11. Review.

11323.     Weinberger M. Respiratory infections and asthma: current treatment strategies. Drug Discov Today. 2004 Oct 1;9(19):831-7. Review. 

11324.  Wickelgren I. Immunology. Policing the immune system. Science. 2004 Oct 22;306(5696):596-9.

Therapy:

11325.     Abbott A. Beta-blocker goes on trial as asthma therapy. Nature. 2004 Nov 4;432(7013):7.

11326.     Anchor J, Settipane RA. Appropriate use of epinephrine in anaphylaxis. Am J Emerg Med. 2004 Oct;22(6):488-90.

11327.     Barnes PJ. Decision making in asthma therapy--what is important in clinical practice? Respir Med. 2004 Oct;98 Suppl B:S1-3. 

11328.     Chamberlain LJ, Bauer L.  The crucial role of the vanishing school nurse. Arch Pediatr Adolesc Med. 2004 Nov;158(11):1091; author reply 1091-2. 

11329.     Crompton GK. How to achieve good compliance with inhaled asthma therapy. Respir Med. 2004 Oct;98 Suppl B:S35-40. Review.

11330.     Ducharme FM, Rowe BH.  Intramuscular versus oral methylprednisolone in asthma. Lancet. 2004 Dec 4;364(9450):2000-1.

11331.     Pascual JC, Fleisher AB. Tacrolimus ointment (Protopic) for atopic dermatitis. Skin Therapy Lett. 2004 Nov;9(9):1-5.

11332.     Prakash V, Gupta K, Sharma S, Gaur S N. A comparative evaluation of the efficacy of inhaled beclomethasone dipropionate budesonide and fluticasone propionate in the management of bronchial asthma. Indian Journal of Allergy Asthma and Immunology. 2004 Jan-Jun; 18(1): 33-38.

11333.     Ramires R, Caiaffa MF, Tursi A, Haeggstrom JZ, Macchia L. Novel inhibitory effect on 5-lipoxygenase activity by the anti-asthma drug montelukast. Biochem Biophys Res Commun. 2004 Nov 12;324(2):815-21.

11334.     Schummer W, Schummer C, Wippermann J, Fuchs J. Anaphylactic shock: is vasopressin the drug of choice? Anesthesiology. 2004 Oct;101(4):1025-7. 

11335.     Simons FE. Advances in H1-antihistamines. N Engl J Med. 2004 Nov 18;351(21):2203-17. Review.

11336.     Vanderhoof JA, Young RJ. Current and potential uses of probiotics. Ann Allergy Asthma Immunol. 2004 Nov;93(5 Suppl 3):S33-7. Review.

July 2005
Some Selected Abstracts:

1.

Berger WE, Qaqundah PY, Blake K, Rodriguez-Santana J, Irani AM, Xu J, Goldman M. Safety of budesonide inhalation suspension in infants aged six to twelve months with mild to moderate persistent asthma or recurrent wheeze. J Pediatr. 2005 Jan;146(1):91-5.

Allergy and Asthma Associates of Southern California, Mission Viejo, CA 92691, USA. Weberger@uci.edu

OBJECTIVE: To compare the safety of budesonide inhalation suspension (BIS) with placebo in infants 6 to 12 months of age with mild to moderate persistent asthma or recurrent wheeze. STUDY DESIGN: In this multicenter, randomized, double-blinded, parallel-group, placebo-controlled study, 141 patients received 0.5 mg BIS (n = 48), 1.0 mg BIS (n = 44), or placebo (n = 49) once daily for 12 weeks. The primary variable was adrenal function, based on cosyntropin-stimulated plasma cortisol levels. Spontaneous adverse events and clinical laboratory findings also were monitored. RESULTS: Overall, the types and frequencies of adverse events reported during the study were comparable across treatment groups. The response to cosyntropin stimulation was similar across treatment groups, with no significant difference between BIS treatment and placebo. CONCLUSIONS: The safety profile of BIS was similar to that of placebo, with no suppressive effect on adrenal function in patients 6 to 12 months of age with mild to moderate persistent asthma or recurrent wheeze.

2.

Cheuk DK, Chau TC, Lee SL. A meta-analysis on intravenous magnesium sulphate for treating acute asthma. Arch Dis Child. 2005 Jan;90(1):74-7. Review

Department of Pediatrics and Adolescent Medicine, The University of Hong Kong. cheukkl@hkusua.hku.hk

AIM: To evaluate the effectiveness of intravenous magnesium sulphate in the treatment of acute asthmatic attacks in children by meta-analysis. METHODS: A systematic and comprehensive search of the literature was performed to identify controlled clinical trials of magnesium sulphate in paediatric acute asthma which evaluated outcomes of hospitalisation or short term pulmonary function tests or symptom scores. Unpublished data were searched by personal contacts with authors and specialists. Two reviewers independently assessed trial qualities and synthesised data. Heterogeneity among studies was evaluated by the Cochrane Q test. Outcome data were pooled by random or fixed effect models depending on presence or absence of heterogeneity. RESULTS: Five randomised placebo controlled trials involving a total of 182 patients were identified. They compared intravenous magnesium sulphate to placebo in treating paediatric patients with moderate to severe asthmatic attacks in the emergency department, with co-therapies of inhaled beta2 agonists and systemic steroids. The studies were of high quality with results judged to be valid. Four studies showed that magnesium sulphate was effective, while one study found it ineffective. There was no significant heterogeneity in the primary outcome of hospitalisation. In the fixed effect model, magnesium sulphate is effective in preventing hospitalisation (OR 0.290, 95% CI 0.143 to 0.589). The number needed to treat is 4 (95% CI 3 to 8). Secondary outcomes of short term pulmonary function tests and clinical symptom scores also showed significant improvement. CONCLUSION: Intravenous magnesium sulphate probably provides additional benefit in moderate to severe acute asthma in children treated with bronchodilators and steroids.

3.

Nasser M, Bitterman-Deutsch O, Nassar F. Intravenous immunoglobulin for treatment of toxic epidermal necrolysis. Am J Med Sci. 2005 Feb;329(2):95-8.

Department of Internal Medicine E, Western Galilee Hospital, Nahariya, Israel.

We report three female patients suffering from toxic epidermal necrolysis, with 30% to 70% epidermal detachment. Alleged causative agents were dipyrone, dibenzazepine, and allopurinol. All patients were treated by intravenous immunoglobulins (IVIG) and survived without further complications, although poor prognostic factors such as concomitant diabetes, large areas of epidermal detachment, and pancytopenia were present. We report these cases with emphasis on the concept that prompt diagnosis, withdrawal of causative drugs, and immediate treatment are imperative for the favorable outcome of the disease. Our patients can be added to the list of those patients who were successfully treated by IVIG, as indicated in this review of the literature.

Diagnosis, Diagnostics, Immunodiagnosis & Immunodiagnostics:

 

  1. Ajith C, Somesh G, Kumar B. Iatrogenic swollen penis. Sex Transm Infect. 2005 Feb;81(1):15-6.

  2. Bansal PJ, Marsh R, Patel B, Tobin MC. Recognition, evaluation, and treatment of anaphylaxis in the child care setting. Ann Allergy Asthma Immunol. 2005 Jan;94(1):55-9.

  3. Black PN. Does atopy protect against enteric infections? Allergy. 2005 Jan;60(1):30-4. Review.

  4. Davis AE 3rd. The pathophysiology of hereditary angioedema. Clin Immunol. 2005 Jan;114(1):3-9. Review.

  5. Falliers CJ. Emergent asthma: endogenous, exogenous, or iatrogenous. Chest. 2005 Feb;127(2):427-9.

  6. Harding SM. Gastroesophageal reflux: a potential asthma trigger. Immunol Allergy Clin North Am. 2005 Feb;25(1):131-48. Review.

  7. Hurwitz EL, Morgenstern H. Vaccination and risk of allergic disease. Am J Public Health. 2005 Jan;95(1):6;

  8. Kamada N, Utani A, Yoneyama K, Kobayashi T, Momota Y, Matsumoto F, Nakada T, Hirasawa H, Shinkai H. Absence of re-epithelialization in a fatal case of toxic epidermal necrolysis: is hyperbilirubinemia a culprit? Arch Dermatol. 2005 Jan;141(1):107-9.

  9. Kuczkowski KM. Anaphylaxis and anesthesia. Minerva Anestesiol. 2005 Jan-Feb;71(1-2):54-5.

  10. Marone G, Triggiani M, de Paulis A. Mast cells and basophils: friends as well as foes in bronchial asthma? Trends Immunol. 2005 Jan;26(1):25-31. Review.

  11. Tan WC. Viruses in asthma exacerbations. Curr Opin Pulm Med. 2005 Jan;11(1):21-6. Review.

  12. Zuraw BL. Current and future therapy for hereditary angioedema. Clin Immunol. 2005 Jan;114(1):10-6. Review.

  1. Adler A, Tager I, Quintero DR. Decreased prevalence of asthma among farm-reared children compared with those who are rural but not farm-reared. J Allergy Clin Immunol. 2005 Jan;115(1):67-73.

  2. Apgar BS, Greenberg G, Yen G. Prevention of group B streptococcal disease in the newborn. A

  3. m Fam Physician. 2005 Mar 1;71(5):903-10. Review. 

  4. Ashworth SW, Denny MA. Images in emergency medicine. Henoch-Schonlein purpura. Ann Emerg Med. 2005 Feb;45(2):221, 230.

  5. Ashworth SW. Toxic epidermal necrolysis: an image case. Ann Emerg Med. 2005 Feb;45(2):109, 156.

  6. Austin JB, Selvaraj S, Godden D, Russell G. Deprivation, smoking, and quality of life in asthma. Arch Dis Child. 2005 Mar;90(3):253-7.

  7. Berger WE, Qaqundah PY, Blake K, Rodriguez-Santana J, Irani AM, Xu J, Goldman M. Safety of budesonide inhalation suspension in infants aged six to twelve months with mild to moderate persistent asthma or recurrent wheeze. J Pediatr. 2005 Jan;146(1):91-5.

  8. Bussamra MH, Cukier A, Stelmach R, Rodrigues JC. Evaluation of the magnitude of the bronchodilator response in children and adolescents with asthma. Chest. 2005 Feb;127(2):530-5.

  9. Chan KS, Keeler E, Schonlau M, Rosen M, Mangione-Smith R. How do ethnicity and primary language spoken at home affect management practices and outcomes in children and adolescents with asthma? Arch Pediatr Adolesc Med. 2005 Mar;159(3):283-9.

  10. Cheuk DK, Chau TC, Lee SL. A meta-analysis on intravenous magnesium sulphate for treating acute asthma. Arch Dis Child. 2005 Jan;90(1):74-7. Review.

  11. Chinn S. Concurrent trends in asthma and obesity. Thorax. 2005 Jan;60(1):3-4.

  12. Colice GL, Stampone P, Leung DY, Szefler SJ. Oral corticosteroids in poorly controlled asthma. J Allergy Clin Immunol. 2005 Jan;115(1):200-1.

  13. Coskun B, Ozturk P, Saral Y. Are erythema nodosum-like lesions and superficial thrombophlebitis prodromal in terms of visceral involvement in Behcet's disease? Int J Clin Pract. 2005 Jan;59(1):69-71.

  14. de Koning HJ. Errors in "family" practice. Lancet. 2005 Mar 12;365(9463):1001. 

  15. de Meer G, Marks GB, de Jongste JC, Brunekreef B. Airway responsiveness to hypertonic saline: dose-response slope or PD15? Eur Respir J. 2005 Jan;25(1):153-8.

  16. Dinh TA, Friedman J, Higuera S. Plastic surgery management in pediatric meningococcal-induced purpura fulminans. Clin Plast Surg. 2005 Jan;32(1):117-21, ix.

  17. Dundas I, Chan EY, Bridge PD, McKenzie SA. Diagnostic accuracy of bronchodilator responsiveness in wheezy children. Thorax. 2005 Jan;60(1):13-6.

  18. Edlich RF, Winters KL, Woodard CR, Britt LD, Long WB 3rd. Massive soft tissue infections: necrotizing fasciitis and purpura fulminans. J Long Term Eff Med Implants. 2005;15(1):57-65. Review.

  19. Enarson DA. Fostering a spirit of critical thinking: the ISAAC story. Int J Tuberc Lung Dis. 2005 Jan;9(1):1.

  20. Eneli I, Sadri K, Camargo C Jr, Barr RG. Acetaminophen and the risk of asthma: the epidemiologic and pathophysiologic evidence. Chest. 2005 Feb;127(2):604-12. Review.

  21. Fox DJ, Gray TP, Fath-Ordoubadi F. Myocardial infarction after aspirin treatment. J R Soc Med. 2005 Jan;98(1):21-3.

  22. Fu KI, Yagi S, Mashimo Y, Sugitani K, Imamaki K, Yanagisawa M, Maekawa S, Morimoto Y, Fujimori T. Regression of Helicobacter pylori-negative duodenal ulcers complicated by Schonlein-Henoch purpura with H. pylori eradication therapy: the first report. Dig Dis Sci. 2005 Feb;50(2):381-4. 

  23. George EL, Panos A. Does a high WBC count signal infection? Nursing. 2005 Jan;35(1):20-1.

  24. German BT. Systemic effects of crotalid envenomation mislabeled as anaphylaxis. Ann Emerg Med. 2005 Jan;45(1):101; 

  25. Gibbons D. An audit of the management of acute asthma in accident and emergency. Nurs Times. 2005 Feb 8-14;101(6):55-8. 

  26. Gold BD. Asthma and gastroesophageal reflux disease in children: exploring the relationship. J Pediatr. 2005 Mar;146(3 Suppl):S13-20. Review. 

  27. Gold BD. Care at the front line: clinical decisions in the management of pediatric acid-related disorders. J Pediatr. 2005 Mar;146(3 Suppl):S1-2.

  28. Gonzalez-Gay MA, Garcia-Porrua C, Pujol RM. Clinical approach to cutaneous vasculitis. Curr Opin Rheumatol. 2005 Jan;17(1):56-61. Review. 

  29. Halling SF, Soderberg MP, Berg UB. Henoch Schonlein nephritis: clinical findings related to renal function and morphology. Pediatr Nephrol. 2005 Jan;20(1):46-51. 

  30. Held-Warmkessel J. Managing three critical cancer complications. Nursing. 2005 Jan;35(1):58-63; quiz 63-4. Review. 

  31. Hmouda H, Laouani-Kechrid C, Nejib Karoui M, Denguezli M, Nouira R, Ghannouchi G. A rare case of streptomycin-induced toxic epidermal necrolysis in a patient with tuberculosis: a therapeutic dilemma. Ann Pharmacother. 2005 Jan;39(1):165-8. 

  32. Hoppu U, Rinne M, Salo-Vaananen P, Lampi AM, Piironen V, Isolauri E.  Vitamin C in breast milk may reduce the risk of atopy in the infant. Eur J Clin Nutr. 2005 Jan;59(1):123-8. 

  33. Jesic R, Culafic D, Bonaci-Nikolic B. Hereditary angioedema presenting with recurrent ascites. Dig Dis Sci. 2005 Jan;50(1):24-6.

  34. Klote MM, Nelson MR, Engler RJ. Autoimmune urticaria response to high-dose intravenous immunoglobulin. Ann Allergy Asthma Immunol. 2005 Feb;94(2):307-8.

  35. Knight-Madden JM, Forrester TS, Lewis NA, Greenough A. Asthma in children with sickle cell disease and its association with acute chest syndrome. Thorax. 2005 Mar;60(3):206-10.

  36. Lapsley P. Itching for a solution. BMJ. 2005 Mar 5;330(7490):522.

  37. Lusi EA, Guarascio P. A target rash. Lancet. 2005 Feb 26;365(9461):784.

  38. Martel MJ, Rey E, Beauchesne MF, Perreault S, Lefebvre G, Forget A, Blais L.  Use of inhaled corticosteroids during pregnancy and risk of pregnancy induced hypertension: nested case-control study. BMJ. 2005 Jan 29;330(7485):230.

  39. Martins P, Borrego LM, Pires G, Pinto PL, Afonso AR, Rosado-Pinto J. Sheep and goat's milk allergy--a case study. Allergy. 2005 Jan;60(1):129-30.

  40. Maskell NA, Davies CW, Nunn AJ, Hedley EL, Gleeson FV, Miller R, Gabe R, Rees GL, Peto TE, Woodhead MA, Lane DJ, Darbyshire JH, Davies RJ; First Multicenter Intrapleural Sepsis Trial (MIST1) Group. U.K. Controlled trial of intrapleural streptokinase for pleural infection. N Engl J Med. 2005 Mar 3;352(9):865-74.

  41. McDougall CM, Ismail SK, Ormerod A. Acute haemorrhagic oedema of infancy. Arch Dis Child. 2005 Mar;90(3):316.

  42. Nasser M, Bitterman-Deutsch O, Nassar F. Intravenous immunoglobulin for treatment of toxic epidermal necrolysis. Am J Med Sci. 2005 Feb;329(2):95-8.

  43. O'Byrne PM, Bisgaard H, Godard PP, Pistolesi M, Palmqvist M, Zhu Y, Ekstrom T, Bateman ED. Budesonide/formoterol combination therapy as both maintenance and reliever medication in asthma. Am J Respir Crit Care Med. 2005 Jan 15;171(2):129-36.

  44. Park MA, Li JT. Diagnosis and management of penicillin allergy. Mayo Clin Proc. 2005 Mar;80(3):405-10. Review. 

  45. Plunkett A, Beattie RM. Recurrent abdominal pain in childhood. J R Soc Med. 2005 Mar;98(3):101-6. Review. 

  46. Reddel HK, Vincent SD, Civitico J. The need for standardisation of peak flow charts. Thorax. 2005 Feb;60(2):164-7. Review. 

  47. Sanchez-Borges M, Suarez-Chacon R, Capriles-Hulett A, Caballero-Fonseca F.  An update on oral anaphylaxis from mite ingestion. Ann Allergy Asthma Immunol. 2005 Feb;94(2):216-20; quiz 220-2, 306. Review.

  48. Schatz M. Breathing for two: now we can all breathe a little easier.J Allergy Clin Immunol. 2005 Jan;115(1):31-3. Review. 

  49. Shaheen SO, Newson RB, Henderson AJ, Headley JE, Stratton FD, Jones RW, Strachan DP; ALSPAC Study Team. Prenatal paracetamol exposure and risk of asthma and elevated immunoglobulin E in childhood. Clin Exp Allergy. 2005 Jan;35(1):18-25. 

  50. Sicherer SH. Food protein-induced enterocolitis syndrome: case presentations and management lessons. J Allergy Clin Immunol. 2005 Jan;115(1):149-56. 

  51. Tilley SL, Boucher RC. A1 antagonism in asthma: better than coffee? J Clin Invest. 2005 Jan;115(1):13-6.

  52. Williams PM, Conklin RJ. Erythema multiforme: a review and contrast from Stevens-Johnson syndrome/toxic epidermal necrolysis. Dent Clin North Am. 2005 Jan;49(1):67-76, viii. Review.
Pathogenesis

  1. Ajith C, Somesh G, Kumar B. Iatrogenic swollen penis. Sex Transm Infect. 2005 Feb;81(1):15-6.

  2. Bansal PJ, Marsh R, Patel B, Tobin MC. Recognition, evaluation, and treatment of anaphylaxis in the child care setting. Ann Allergy Asthma Immunol. 2005 Jan;94(1):55-9.

  3. Black PN. Does atopy protect against enteric infections? Allergy. 2005 Jan;60(1):30-4. Review.

  4. Davis AE 3rd. The pathophysiology of hereditary angioedema. Clin Immunol. 2005 Jan;114(1):3-9. Review.

  5. Falliers CJ. Emergent asthma: endogenous, exogenous, or iatrogenous. Chest. 2005 Feb;127(2):427-9.

  6. Harding SM. Gastroesophageal reflux: a potential asthma trigger. Immunol Allergy Clin North Am. 2005 Feb;25(1):131-48. Review.

  7. Hurwitz EL, Morgenstern H. Vaccination and risk of allergic disease. Am J Public Health. 2005 Jan;95(1):6;

  8. Kamada N, Utani A, Yoneyama K, Kobayashi T, Momota Y, Matsumoto F, Nakada T, Hirasawa H, Shinkai H. Absence of re-epithelialization in a fatal case of toxic epidermal necrolysis: is hyperbilirubinemia a culprit? Arch Dermatol. 2005 Jan;141(1):107-9.

  9. Kuczkowski KM. Anaphylaxis and anesthesia. Minerva Anestesiol. 2005 Jan-Feb;71(1-2):54-5.

  10. Marone G, Triggiani M, de Paulis A. Mast cells and basophils: friends as well as foes in bronchial asthma? Trends Immunol. 2005 Jan;26(1):25-31. Review.

  11. Tan WC. Viruses in asthma exacerbations. Curr Opin Pulm Med. 2005 Jan;11(1):21-6. Review.

  12. Zuraw BL. Current and future therapy for hereditary angioedema. Clin Immunol. 2005 Jan;114(1):10-6. Review.

October 2005
 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

Some Selected Abstracts:

1.

Aversano M, Caiazzo P, Iorio G, Ponticiello L, Lagana B, Leccese F. Improvement of chronic idiopathic urticaria with L-thyroxine: a new TSH role in immune response? Allergy. 2005 Apr;60(4):489-93.

Endocrinology Unit ASL NA3, Naples, Italy.

BACKGROUND: The association between chronic idiopathic urticaria (CIU) and autoimmune thyroiditis (AT) is known, as well as major prevalence of antithyroid antibodies in the allergical subjects and other autoimmune diseases. We have evaluated the effects of l-thyroxine on clinical symptoms of CIU in AT patients suggesting the hypothesis of a new thyroid-stimulating hormone (TSH) role in immune system. METHODS: In 20 female patients with CIU + AT, both hypothyroid and euthyroid, we have investigated the therapeutic effects of l-thyroxine dosed to suppress the TSH. Free-T3, Free-T4, TSH, antithyroperoxidase and antithyroglobulin antibodies, total immunoglobulin (Ig)E, Rheuma test and eritro-sedimentation rate were monitored during treatment. Results: In 16 patients a strong decrease of urticaria symptoms has happened after 12 weeks. The TPO Ab and HTG Ab clearly decreased in 14 patients. Furthermore, in two patients with rheumatoid arthritis and in two patients with pollen allergy a strong decrease of rheuma test titer and total IgE has happened. Conclusion: The reason of AT is associated to CIU and others allergical and autoimmune diseases is poorly known. The exclusive hormonal therapy reduces the symptoms of CIU and inflammatory response in many chronic diseases associated to AT. We suggest a stimulatory effect of TSH able to produce considerable changes of the immune response and immune tolerance in patients with AT causing target organs damage. The causal mechanism involves immune, nervous and endocrine system, sharing a common set of hormones, cytokines and receptors, in a unique totally integrated loop (the neuro-immuno-endocrine axis).

2.

Bircher AJ. Symptoms and danger signs in acute drug hypersensitivity. Toxicology. 2005 Apr 15;209(2):201-7.

Allergy Unit, Department of Dermatology, University Hospital Basel, Petersgraben 4, CH-4031 Basel, Switzerland. andreas.bircher@unibas.ch

Early and rapid recognition of severe adverse drug reactions is essential. Prompt withdrawal of the offending drug is the most important action to minimize morbidity and mortality. Dependent on the type of reaction, e.g. in immediate type reactions instant withdrawal and therapy are mandatory, whereas in delayed reactions diagnosis as early as possible may be life-saving. The skin is an important herald organ and may early signal a severe evolution of a cutaneous reaction or involvement of circulating blood cells or internal organs. A synthesis considering all factors should be made to obtain an early and correct diagnosis.

3.

Bryant R. Asthma in the pediatric sickle cell patient with acute chest syndrome. J Pediatr Health Care. 2005 May-Jun;19(3):157-62.

Texas Children's Hospital, Baylor College of Medicine, Houston, Texas, USA. rxbryant@texaschildrenshospital.org

INTRODUCTION: Acute chest syndrome (ACS) is a potential life-threatening complication of sickle cell disease (SCD). The purpose of this study was to identify the frequency of asthma in children with SCD who were diagnosed with ACS. The objective was to determine if an increased frequency of asthma exists in children with SCD and ACS. METHOD: A retrospective descriptive chart review covering the period from June 1997 to June 2002 was conducted on 60 children ranging in age from 1.5 years to 17 years who had SCD and ACS. Cross-tabs analysis and student t tests were used to determine the significance of the occurrence of asthma in children in whom ACS developed. RESULTS: Of the 60 eligible children with SCD, 53% (32/60) had asthma and/or abnormal pulmonary function tests prior to the development of ACS. DISCUSSION: This is the first study to report a slight increase in the frequency of asthma prior to the initial ACS in children with SCD. The small convenience sample size from one center may have been a limitation in this study to detect significant differences between the variables.

4.

Govindarajan G, Bashir Q, Kuppuswamy S, Brooks C. Sweet syndrome associated with furosemide. South Med J. 2005 May;98(5):570-2.

University of Missouri Health Science Center, Department of Internal Medicine, MA 406, One Hospital Drive, Columbia, MO 65212, USA. govindarajang@health.missouri.edu

This case report describes a case of Sweet syndrome (SS) related to use of furosemide in a 46-year-old female who was admitted for treatment of congestive heart failure. Three days after administration of furosemide, the patient had a fever and a skin eruption appeared on her wrists, forearms, and legs. Biopsy of the skin lesion was consistent with SS. Infection was thought to be unlikely because of negative blood cultures, echocardiography, and other imaging studies. Careful review of her medications revealed that the patient received furosemide before the appearance of the skin eruption and fever. After discontinuation of furosemide, the patient's skin lesion and fever resolved. A MEDLINE search from June 1966 to May 2004 revealed only one reference documenting the association of SS with furosemide administration. Patients who have development of SS without an obvious cause should have their medication list closely reviewed.

5.

Janse AJ, Sinnema G, Uiterwaal CS, Kimpen JL, Gemke RJ. Quality of life in chronic illness: perceptions of parents and paediatricians. Arch Dis Child. 2005 May;90(5):486-91.

Department of Paediatrics, Wilhelmina Children's Hospital, University Medical Centre Utrecht, Netherlands.

AIMS: To investigate the differences in perception of quality of life between parents of chronically ill children and paediatricians at diagnosis and follow up. Quality of life was assessed using the (HUI3). METHODS: Longitudinal study (July 1999-January 2002) of 37 paediatricians and 181 parents of patients (children aged 1-17 years) with cystic fibrosis admitted for a pneumonia or patients with newly diagnosed acute lymphatic leukaemia, juvenile idiopathic arthritis, or asthma. Main outcome measure was percentage agreement on the attributes of the HUI3 between parents and paediatricians. RESULTS: Differences in perception of health and wellbeing between paediatricians and parents of children with a chronic disease were found, not only at diagnosis but also after a period of follow up. Differences were particularly clear in the subjective attributes emotion (range of agreement 28-68%) and pain/discomfort (range of agreement 11-33%). In all patient groups, at baseline and follow up, the paediatrician assessed the patient to have less pain/discomfort in comparison to the parents. Despite a prolonged patient- paediatrician relationship, differences at follow up did not decrease compared to baseline. CONCLUSION: At the onset of a chronic disease, but also after a period of follow up, quality of life of paediatric patients may be misunderstood by healthcare professionals, especially in the subjective attributes. Systematic assessment of quality of life may contribute to better understanding between physicians and parents.

6.

Letko E, Papaliodis DN, Papaliodis GN, Daoud YJ, Ahmed AR, Foster CS. Stevens-Johnson syndrome and toxic epidermal necrolysis: a review of the literature. Ann Allergy Asthma Immunol. 2005 Apr;94(4):419-36; quiz 436-8, 456.

Department of Ophthalmology, Uveitis and Immunology Service, The Massachusetts Eye and Ear Infirmary, Harvard Medical School, Boston, Massachusetts 02114, USA.

OBJECTIVE: To perform a comprehensive review of Stevens-Johnson syndrome and toxic epidermal necrolysis. DATA SOURCES: A MEDLINE search was performed for the years 1975 to 2003 using the keywords Stevens-Johnson syndrome and toxic epidermal necrolysis to identify relevant articles published in English in peer-reviewed journals. STUDY SELECTION: All clinical studies that reported on 4 or more patients, review articles, and experimental studies that concerned disease mechanisms were selected and further analyzed. Clinical reports that included fewer than 4 patients were selected only if they were believed to carry a significant message about disease mechanism or therapy. RESULTS: Stevens-Johnson syndrome and toxic epidermal necrolysis seem to be variants of the same disease with differing severities. A widely accepted consensus regarding diagnostic criteria and therapy does not exist at present. Despite the recent experimental studies, the pathogenic mechanisms of these diseases remain unknown. Although progress in survival through early hospitalization in specialized burn units has been made, the prevalence of life-long disability from the ocular morbidity of Stevens-Johnson syndrome and toxic epidermal necrolysis has remained unchanged for the past 35 years. Further progress depends on modification of the acute phase of the disease rather than continuation of supportive care. The available published evidence indicates that a principal problem in the pathogenesis is immunologic and that immunomodulatory intervention with short-term, high-dose intravenous steroids or intravenous immunoglobulin holds the most promise for effective change in survival and long-term morbidity. CONCLUSIONS: The results of this review call for a widely accepted consensus on diagnostic criteria for Stevens-Johnson and toxic epidermal necrolysis and multicenter collaboration in experimental studies and clinical trials that investigate disease mechanisms and novel therapeutic interventions, respectively.

7.

Peacock ME, Park DS, Swiec GD, Erley KJ. Perioral angioedema associated with angiotensin-converting enzyme inhibitor. J Periodontol. 2005 Apr;76(4):651-4.

U.S. Army, Landstuhl, Germany. mark.peacock@lnd.amedd.army.mil

BACKGROUND: Angioedema is a non-pruritic swelling usually limited to the skin and mucous membranes of the face and perioral soft tissues. It can be life threatening but usually is not, and can be managed with conservative medical treatment unless the airway is endangered. Recent reports suggest that angiotensin-converting enzyme (ACE) inhibitors can predispose and/or precipitate angioedema, with a predilection toward patients of African American ancestry. METHODS: This case report involved a 65-year-old African American female who was being treated surgically for localized chronic periodontitis. The procedure was performed without incident, and the patient was alert and stable when released. The next day, the patient called and reported that her lips were swollen. She stated that this had happened a number of times over the past several years, sometimes related to eating shellfish and other times without any known precipitating factor. All previous episodes of perioral swelling occurred after ACE inhibitor therapy had been initiated. RESULTS: The patient was in no distress, with no other site involvement. She was prescribed oral hydroxyzine and her appearance returned to normal after 5 days. Although the patient had experienced previous episodes of angioedema, none had been in response to any dental procedure. She was referred to the Allergy and Immunology Clinic for skin testing, the results of which were negative to shellfish with good controls. Other potentiating etiologies were also ruled out by the allergist. CONCLUSIONS: Angioedema is a recognized possible side effect of ACE inhibitor therapy. The exact mechanism by which ACE inhibitors induce angioedema is not known, although the risk of occurrence is much greater in African Americans. Practitioners should be alert to this potentially fatal condition in patients who take ACE inhibitors or the newer angiotensin II receptor blockers (ARBs).

8.

Plotkin SA. Vaccines: past, present and future. Nat Med. 2005 Apr;11(4 Suppl):S5-11.

Sanofi Pasteur and the University of Pennsylvania, 4650 Wismer Road, Doylestown, Pennsylvania 18901, USA. Stanley.Plotkin@sanofipasteur.com

The vaccines developed over the first two hundred years since Jenner's lifetime have accomplished striking reductions of infection and disease wherever applied. Pasteur's early approaches to vaccine development, attenuation and inactivation, are even now the two poles of vaccine technology. Today, purification of microbial elements, genetic engineering and improved knowledge of immune protection allow direct creation of attenuated mutants, expression of vaccine proteins in live vectors, purification and even synthesis of microbial antigens, and induction of a variety of immune responses through manipulation of DNA, RNA, proteins and polysaccharides. Both noninfectious and infectious diseases are now within the realm of vaccinology. The profusion of new vaccines enables new populations to be targeted for vaccination, and requires the development of routes of administration additional to injection. With all this come new problems in the production, regulation and distribution of vaccines.

9.

Sabina AB, Williams AL, Wall HK, Bansal S, Chupp G, Katz DL. Yoga intervention for adults with mild-to-moderate asthma: a pilot study. Ann Allergy Asthma Immunol. 2005 May;94(5):543-8.

Yale-Griffin Prevention Research Center, Derby, Connecticut 06418, USA.

BACKGROUND: Preliminary studies investigating yoga and breath work for treating asthma have been promising. Several randomized controlled trials have shown a benefit from yoga postures and breathing vs control, but the control in these cases involved no intervention other than usual care. This study advances the field by providing an active control. OBJECTIVE: To determine the effectiveness and feasibility of a yoga and breath work intervention for improving clinical indices and quality of life in adults with mild-to-moderate asthma. METHODS: A randomized, controlled, double-masked clinical trial was conducted between October 1, 2001, and March 31, 2003. Random assignment was made to either a 4-week yoga intervention that included postures and breath work or a stretching control condition. Outcome measures were evaluated at 4, 8, 12, and 16 weeks and included the Mini Asthma Quality of Life Questionnaire, rescue inhaler use, spirometry, symptom diaries, and health care utilization. RESULTS: Sixty-two participants were randomized to the intervention and control groups, and 45 completed the final follow-up measures. Intention-to-treat analysis was performed. Significant within-group differences in postbronchodilator forced expiratory volume in 1 second and morning symptom scores were apparent in both groups at 4 and 16 weeks; however, no significant differences between groups were observed on any outcome measures. CONCLUSIONS: Iyengar yoga conferred no appreciable benefit in mild-to-moderate asthma. Circumstances under which yoga is of benefit in asthma management, if any, remain to be determined.

Diagnosis, Diagnostics, Immunodiagnosis & Immunodiagnostics:

12411.     Agterof MJ, Biesma DH.  Images in clinical Medicine. Bortezomib-induced skin lesions. N Engl J Med. 2005 Jun 16;352(24):2534.

12412.     Ahmed T, Vaezi MF. The role of pH monitoring in extraesophageal gastroesophageal reflux disease. Gastrointest Endosc Clin N Am. 2005 Apr;15(2):319-31. Review.

12413.     Alobid I, Benitez P, Bernal-Sprekelsen M, Roca J, Alonso J, Picado C, Mullol J. Nasal polyposis and its impact on quality of life: comparison between the effects of medical and surgical treatments. Allergy. 2005 Apr;60(4):452-8.

12414.     American Academy of Family Physicians. Information from your family doctor. Treating my child's asthma. Am Fam Physician. 2005 May 15;71(10):1969.

12415.     Aversano M, Caiazzo P, Iorio G, Ponticiello L, Lagana B, Leccese F. Improvement of chronic idiopathic urticaria with L-thyroxine: a new TSH role in immune response? Allergy. 2005 Apr;60(4):489-93. 

12416.     Baydur A.  Not all that comes out is hot air. Chest. 2005 May;127(5):1482-5.

12417.     Bergeron C, Boulet LP, Hamid Q. Obesity, allergy and immunology. J Allergy Clin Immunol. 2005 May;115(5):1102-4. Review.

12418.     Berkman N, Avital A, Breuer R, Bardach E, Springer C, Godfrey S. Exhaled nitric oxide in the diagnosis of asthma: comparison with bronchial provocation tests. Thorax. 2005 May;60(5):383-8. 

12419.     Beuther DA, Sutherland ER. Obesity and pulmonary function testing. J Allergy Clin Immunol. 2005 May;115(5):1100-1.

12420.     Bircher AJ. Symptoms and danger signs in acute drug hypersensitivity. Toxicology. 2005 Apr 15;209(2):201-7. Review.

12421.     Bischoff S, Crowe SE.  Gastrointestinal food allergy: new insights into pathophysiology and clinical perspectives. Gastroenterology. 2005 Apr;128(4):1089-113. Review. 

12422.     Boushey HA, Sorkness CA, King TS, Sullivan SD, Fahy JV, Lazarus SC, Chinchilli VM, Craig TJ, Dimango EA, Deykin A, Fagan JK, Fish JE, Ford JG, Kraft M, Lemanske RF Jr, Leone FT, Martin RJ, Mauger EA, Pesola GR, Peters SP, Rollings NJ, Szefler SJ, Wechsler ME, Israel E; National Heart, Lung, and Blood Institute's Asthma Clinical Research Network.  Daily versus as-needed corticosteroids for mild persistent asthma. N Engl J Med. 2005 Apr 14;352(15):1519-28. 

12423.     Bousquet PJ, Co-Minh HB, Demoly P. Isolated urticaria to ondansetron and successful treatment with granisetron. Allergy. 2005 Apr;60(4):543-4.

12424.     Brockow K. Contrast media hypersensitivity--scope of the problem. Toxicology. 2005 Apr 15;209(2):189-92. Review.

12425.     Bruce C, Thomas PS. The effect of marimastat, a metalloprotease inhibitor, on allergen-induced asthmatic hyper-reactivity. Toxicol Appl Pharmacol. 2005 Jun 1;205(2):126-32.

12426.     Bryant R. Asthma in the pediatric sickle cell patient with acute chest syndrome. J Pediatr Health Care. 2005 May-Jun;19(3):157-62.

12427.     Chen MJ, Wang TE, Chang WH, Tsai SJ, Liao WS. Endoscopic findings in a patient with Henoch-Schonlein purpura. World J Gastroenterol. 2005 Apr 21;11(15):2354-6. 

12428.     Chhabra SK.  Premenstrual asthma. Indian J Chest Dis Allied Sci. 2005 Apr-Jun;47(2):109-16. Review.

12429.     Chhabra SK. Guidelines for management of asthma: the gaps between theory and practice. Indian J Chest Dis Allied Sci. 2005 Apr-Jun;47(2):77-80.

12430.     Chuchalin A, Kasl M, Bengtsson T, Nihlen U, Rosenborg J. Formoterol used as needed in patients with intermittent or mild persistent asthma. Respir Med. 2005 Apr;99(4):461-70.

12431.     Corry DB. Resolving a case of split personality. Nat Immunol. 2005 May;6(5):432-4.

12432.     Courtney AU, McCarter DF, Pollart SM.  Childhood asthma: treatment update. Am Fam Physician. 2005 May 15;71(10):1959-68. Review.

12433.     Covar RA, Cool C, Szefler SJ. Progression of asthma in childhood. J Allergy Clin Immunol. 2005 Apr;115(4):700-7.

12434.     Demoly P.  Anaphylactic reactions--value of skin and provocation tests. Toxicology. 2005 Apr 15;209(2):221-3.

12435.     Forastiere F, Sunyer J, Farchi S, Corbo G, Pistelli R, Baldacci S, Simoni M, Agabiti N, Perucci CA, Viegi G. Number of offspring and maternal allergy. Allergy. 2005 Apr;60(4):510-4.

12436.     Freiman A. Dermacase. Henoch-Schonlein purpura. Can Fam Physician. 2005 Apr;51:511-2. Review.

12437.     Gaston B.  Inhaled corticosteroid dose reduction in childhood asthma: is nitrosopnea informative? Am J Respir Crit Care Med. 2005 May 15;171(10):1065-6.

12438.     Govindarajan G, Bashir Q, Kuppuswamy S, Brooks C. Sweet syndrome associated with furosemide. South Med J. 2005 May;98(5):570-2. Review. 

12439.     Harboe T, Guttormsen AB, Irgens A, Dybendal T, Florvaag E. Anaphylaxis during anesthesia in Norway: a 6-year single-center follow-up study. Anesthesiology. 2005 May;102(5):897-903.

12440.     Hehn J, Brocker EB, Goebeler M.  Angioedema, eosinophilia, and fever. Arch Dermatol. 2005 May;141(5):633-8.

12441.     High WA, Hoang MP, Miller MD. Pruritic urticarial papules and plaques of pregnancy with unusual and extensive palmoplantar involvement. Obstet Gynecol. 2005 May;105(5 Pt 2):1261-4.

12442.     Hoffmann-Sommergruber K; SAFE consortium. The SAFE project: 'plant food allergies: field to table strategies for reducing their incidence in Europe' an EC-funded study. Allergy. 2005 Apr;60(4):436-42. Review.

12443.     Holten KB; American Academy of Dermatology. How should we care for atopic dermatitis? J Fam Pract. 2005 May;54(5):426-7.

12444.     Janse AJ, Sinnema G, Uiterwaal CS, Kimpen JL, Gemke RJ. Quality of life in chronic illness: perceptions of parents and paediatricians. Arch Dis Child. 2005 May;90(5):486-91.

12445.     Kaur C, Bansal SK, Chhabra SK. Study on serum and urinary cortisol levels of asthmatic patients after treatment with high dose inhaled beclomethasone dipropionate or budesonide. Indian J Chest Dis Allied Sci. 2005 Apr-Jun;47(2):89-95.

12446.     Kimura A, Yoshino H, Yuasa T. Chronic inflammatory demyelinating polyneuropathy in a patient with hyperIgEaemia. J Neurol Sci. 2005 Apr 15;231(1-2):89-93.

12447.     Komericki P, Fellner P, El-Shabrawi Y, Ardjomand N. Keratopathy after ultraviolet B phototherapy. Wien Klin Wochenschr. 2005 Apr;117(7-8):300-2. 

12448.     Korzenik JR. Past and current theories of etiology of IBD: toothpaste, worms, and refrigerators. J Clin Gastroenterol. 2005 Apr;39(4 Suppl 2):S59-65. Review.

12449.     Laroche D. Immediate reactions to contrast media: mediator release and value of diagnostic testing. Toxicology. 2005 Apr 15;209(2):193-4. Review. 

12450.     Letko E, Papaliodis DN, Papaliodis GN, Daoud YJ, Ahmed AR, Foster CS. Stevens-Johnson syndrome and toxic epidermal necrolysis: a review of the literature. Ann Allergy Asthma Immunol. 2005 Apr;94(4):419-36; quiz 436-8, 456. Review.

12451.     Luskin AT. What the asthma end points we know and love do and do not tell us. J Allergy Clin Immunol. 2005 Apr;115(4 Suppl):S539-45. Review.

12452.     Malmberg LP, Turpeinen H, Rytila P, Sarna S, Haahtela T. Determinants of increased exhaled nitric oxide in patients with suspected asthma. Allergy. 2005 Apr;60(4):464-8.

12453.     Mansur AT, Aydingoz IA. A case of toxic epidermal necrolysis with lesions mostly on sun-exposed skin. Photodermatol Photoimmunol Photomed. 2005 Apr;21(2):100-2. 

12454.     Matsumoto K, Shimanouchi Y, Kawakubo K, Oishi N, Wakiguchi H, Futamura K, Saito H.  Infantile eczema at one month of age is associated with cord blood eosinophilia and subsequent development of atopic dermatitis and wheezing illness until two years of age. Int Arch Allergy Immunol. 2005;137 Suppl 1:69-76.

12455.     Nel A. Atmosphere. Air pollution-related illness: effects of particles. Science. 2005 May 6;308(5723):804-6.

12456.     Nicholson PJ, Cullinan P, Taylor AJ, Burge PS, Boyle C.  Evidence based guidelines for the prevention, identification, and management of occupational asthma. Occup Environ Med. 2005 May;62(5):290-9. Review. 

12457.     Nunnelee JD. Summer injuries. Bites & stings. RN. 2005 Apr;68(4):56-8, 60-1; quiz 62. Review.

12458.     Palomares O, Cuesta-Herranz J, Rodriguez R, Villalba M. A recombinant precursor of the mustard allergen Sin a 1 retains the biochemical and immunological features of the heterodimeric native protein. Int Arch Allergy Immunol. 2005 May;137(1):18-26.

12459.     Radcliffe M, Scadding G, Brown HM. Lupin flour anaphylaxis. Lancet. 2005 Apr 9-15;365(9467):1360.

12460.     Ritz BW, Lord RS. Case study: The effectiveness of a dietary supplement regimen in reducing IgG-mediated food sensitivity in ADHD. Altern Ther Health Med. 2005 May-Jun;11(3):72-5.

12461.     Sabina AB, Williams AL, Wall HK, Bansal S, Chupp G, Katz DL. Yoga intervention for adults with mild-to-moderate asthma: a pilot study. Ann Allergy Asthma Immunol. 2005 May;94(5):543-8.

12462.     Saeed SA. Hyposensitization. J Coll Physicians Surg Pak. 2005 Apr;15(4):250.

12463.     Sahin MT, Ozturkcan S, Inanir I, Filiz EE. Norfloxacin-induced toxic epidermal necrolysis. Ann Pharmacother. 2005 Apr;39(4):768-70.

12464.     Shirai T, Matsui T, Suzuki K, Chida K. Effect of pet removal on pet allergic asthma. Chest. 2005 May;127(5):1565-71.

12465.     Shivbalan S, Balasubramanian S, Anandnathan K. What do parents of asthmatic children know about asthma?: An Indian perspective. Indian J Chest Dis Allied Sci. 2005 Apr-Jun;47(2):81-7. 

12466.     Song TT, Nelson MR, Chang JH, Engler RJ, Chowdhury BA. Adequacy of the epinephrine autoinjector needle length in delivering epinephrine to the intramuscular tissues. Ann Allergy Asthma Immunol. 2005 May;94(5):539-42.

12467.     Sood A. Does obesity weigh heavily on the health of the human airway? J Allergy Clin Immunol. 2005 May;115(5):921-4.

12468.     Szefler SJ. Airway remodeling: therapeutic target or not? Am J Respir Crit Care Med. 2005 Apr 1;171(7):672-3.

12469.     Szefler SJ. Facing the challenges of childhood asthma: what changes are necessary? J Allergy Clin Immunol. 2005 Apr;115(4):685-8. Review.

12470.     Tamura G, Suda Y. Images in clinical medicine. Airway dilatation after inhalation of a beta-agonist. N Engl J Med. 2005 Apr 14;352(15):e14.

12471.     Tuchinda C, Leenutaphong V, Sudtim S, Lim HW. Fixed solar urticaria induced by UVA and visible light: a report of a case. Photodermatol Photoimmunol Photomed. 2005 Apr;21(2):97-9. Review.

12472.     Varadarajulu S. Urticaria and angioedema. Controlling acute episodes, coping with chronic cases. Postgrad Med. 2005 May;117(5):25-31. Review.

12473.     Viljanen M, Savilahti E, Haahtela T, Juntunen-Backman K, Korpela R, Poussa T, Tuure T, Kuitunen M. Probiotics in the treatment of atopic eczema/dermatitis syndrome in infants: a double-blind placebo-controlled trial. Allergy. 2005 Apr;60(4):494-500.

12474.     Wang J, Sicherer SH. Anaphylaxis following ingestion of candy fruit chews. Ann Allergy Asthma Immunol. 2005 May;94(5):530-3.

12475.     Welt K, Hinrichs R, Ott S, Thalmann M, Dieckmannken J, Schneider LA, Staib G, Scharffetter-Kochanek K. Anaphylaxis after the ingestion of lamb meat. Allergy. 2005 Apr;60(4):545.

12476.     Wilson C. Recurrent vulvovaginitis candidiasis; an overview of traditional and alternative therapies. Adv Nurse Pract. 2005 May;13(5):24-9; quiz 30. Review.

12477.     Yawalkar N. Drug-induced exanthems. Toxicology. 2005 Apr 15;209(2):131-4. Review.

Pathogenesis

12478.     Aster RH. Drug-induced immune cytopenias. Toxicology. 2005 Apr 15;209(2):149-53. 

12479.     Berger RE. Fixed drug eruption--a sexually inducible reaction? J Urol. 2005 Jun;173(6):1990.

12480.     Carraro S, Corradi M, Zanconato S, Alinovi R, Pasquale MF, Zacchello F, Baraldi E.  Exhaled breath condensate cysteinyl leukotrienes are increased in children with exercise-induced bronchoconstriction. J Allergy Clin Immunol. 2005 Apr;115(4):764-70.

12481.     Cavani A.  Breaking tolerance to nickel. Toxicology. 2005 Apr 15;209(2):119-21. Review.

12482.     Christiansen C.  X-ray contrast media--an overview. Toxicology. 2005 Apr 15;209(2):185-7. Review.

12483.     Cloutier MM, Hall CB, Wakefield DB, Bailit H. Use of asthma guidelines by primary care providers to reduce hospitalizations and emergency department visits in poor, minority, urban children. J Pediatr. 2005 May;146(5):591-7. 

12484.     Currie GP, Lee DK. Beneficial antiinflammatory effects of leukotriene receptor antagonists in asthma. Chest. 2005 Apr;127(4):1458.

12485.     Falcone FH, Pritchard DI. Parasite role reversal: worms on trial. Trends Parasitol. 2005 Apr;21(4):157-60. Review.

12486.     Fineberg SE, Kawabata T, Finco-Kent D, Liu C, Krasner A. Antibody response to inhaled insulin in patients with type 1 or type 2 diabetes. An analysis of initial phase II and III inhaled insulin (Exubera) trials and a two-year extension trial. J Clin Endocrinol Metab. 2005 Jun;90(6):3287-94.

12487.     Gern JE, Rosenthal LA, Sorkness RL, Lemanske RF Jr. Effects of viral respiratory infections on lung development and childhood asthma. J Allergy Clin Immunol. 2005 Apr;115(4):668-74; quiz 675. Review.

12488.     Greenberger PA.  Epinephrine for anaphylaxis. Ann Allergy Asthma Immunol. 2005 May;94(5):515-6.

12489.     Jain S. Proton-pump inhibitor therapy for gastroesophageal reflux disease: does it treat the asthma? Chest. 2005 Apr;127(4):1097-8.

12490.     Kim LS, Riedlinger JE, Baldwin CM, Hilli L, Khalsa SV, Messer SA, Waters RF.  Treatment of seasonal allergic rhinitis using homeopathic preparation of common allergens in the southwest region of the US: a randomized, controlled clinical trial. Ann Pharmacother. 2005 Apr;39(4):617-24.

12491.     Konno S, Golden DB, Schroeder J, Hamilton RG, Lichtenstein LM, Huang SK.  Increased expression of osteopontin is associated with long-term bee venom immunotherapy. J Allergy Clin Immunol. 2005 May;115(5):1063-7.

12492.     Kuehn BM. Therapy takes wheeze out of cat allergies. JAMA. 2005 May 11;293(18):2201.

12493.     Li YF, Langholz B, Salam MT, Gilliland FD. Maternal and grandmaternal smoking patterns are associated with early childhood asthma. Chest. 2005 Apr;127(4):1232-41.

12494.     Linhart B, Hartl A, Jahn-Schmid B, Verdino P, Keller W, Krauth MT, Valent P, Horak F, Wiedermann U, Thalhamer J, Ebner C, Kraft D, Valenta R. A hybrid molecule resembling the epitope spectrum of grass pollen for allergy vaccination. J Allergy Clin Immunol. 2005 May;115(5):1010-6.

12495.     Linneberg A. Hypothesis: urbanization and the allergy epidemic--a reverse case of immunotherapy? Allergy. 2005 Apr;60(4):538-9.

12496.     Liu XS, Xu YJ. Potassium channels in airway smooth muscle and airway hyperreactivity in asthma. Chin Med J (Engl). 2005 Apr 5;118(7):574-80. Review.

12497.     McBrien ME, Webb ST, Breslin. Anaphylaxis and anaesthesia. Br J Anaesth. 2005 Apr;94(4):547-8; author reply 548.

12498.     McKeever TM, Lewis SA, Smit HA, Burney P, Britton JR, Cassano PA.  The association of acetaminophen, aspirin, and ibuprofen with respiratory disease and lung function. Am J Respir Crit Care Med. 2005 May 1;171(9):966-71.

12499.     Mertes PM. Anaphylactic reactions during anaesthesia--let us treat the problem rather than debating its existence. Acta Anaesthesiol Scand. 2005 Apr;49(4):431-3.

12500.     Murch S. Diet, immunity, and autistic spectrum disorders. J Pediatr. 2005 May;146(5):582-4. Review.

12501.     Peacock ME, Park DS, Swiec GD, Erley KJ. Perioral angioedema associated with angiotensin-converting enzyme inhibitor. J Periodontol. 2005 Apr;76(4):651-4.

12502.     Prescott RA, Potter PC. Hypersensitivity to airborne spitting cobra snake venom. Ann Allergy Asthma Immunol. 2005 May;94(5):600-3.

12503.     Rahman M, Haider N. Anticonvulsant hypersensitivity syndrome from addition of lamotrigine to divalproex. Am J Psychiatry. 2005 May;162(5):1021.

12504.     Romano A, Gueant-Rodriguez RM, Viola M, Gaeta F, Caruso C, Gueant JL. Cross-reactivity among drugs: clinical problems. Toxicology. 2005 Apr 15;209(2):169-79. Review.

12505.     Shi HZ. DNA vaccine and asthma therapy. Chin Med J (Engl). 2005 Apr 5;118(7):531-3.

12506.     Szeplaki G, Varga L, Valentin S, Kleiber M, Karadi I, Romics L, Fust G, Farkas H.   Adverse effects of danazol prophylaxis on the lipid profiles of patients with hereditary angioedema. J Allergy Clin Immunol. 2005 Apr;115(4):864-9.

12507.     Thomas M, Crawford I. Best evidence topic report. Glucagon infusion in refractory anaphylactic shock in patients on beta-blockers. Emerg Med J. 2005 Apr;22(4):272-3. Review.

12508.     Williams HC. Clinical practice. Atopic dermatitis. N Engl J Med. 2005 Jun 2;352(22):2314-24. Review.

Vaccines:

12509.   Plotkin SA. Vaccines: past, present and future. Nat Med. 2005 Apr;11(4 Suppl):S5-11

Therapy:

12510.     Cace N, Brusich S, Dessardo S, Ahel J. Cardiopulmonary bypass in a child with hereditary angioedema. Pediatr Int. 2005 Apr;47(2):214-6.

12511.     Check E. Gene therapists urged to learn more immunology. Nature. 2005 Apr 14;434(7035):812.

12512.     Green R, Ball A. Alpha-agonists for the treatment of anaphylactic shock. Anaesthesia. 2005 Jun;60(6):621-2.

12513.     Kemp SF. Got epinephrine? Many patients with anaphylaxis reportedly stuck with no epinephrine syringes. Ann Allergy Asthma Immunol. 2005 May;94(5):513-4.

12514.     Mennick F. Treating asthma in pregnancy: what's good for women is good for fetuses, too. Am J Nurs. 2005 Apr;105(4):20.

12515.     Muething SE, Kotagal U. Reliability of the health care delivery system. J Pediatr. 2005 May;146(5):581-2.

12516.     Walters JA, Wood-Baker R, Walters EH. Long-acting beta2-agonists in asthma: an overview of Cochrane systematic reviews. Respir Med. 2005 Apr;99(4):384-95. Review.

Back