LEISHMANIASIS

( SEVAMED 2003)

(Diagnosis, Diagnostics, Immunodiagnosis, Immunodiagnostics, Pathogenesis, Vaccines & Drugs)

January 2003

6086. Arya SC. Enzyme-linked immunosorbent assays for diagnosis of leishmaniasis in patients coinfected with human immunodeficiency virus. J Clin Microbiol. 2002 Aug;40(8):3110.

6087. Dey T, Afrin F, Anam K, Ali N. Infectivity and virulence of Leishmania donovani promastigotes: a role for media, source, and strain of parasite. J Eukaryot Microbiol. 2002 Jul-Aug;49(4):270-4.

6088. Gonzalez AC, Martinez E, Carmelo E, Pinero JE, Alonso V, Del Castillo A, Valladares B. Analysis of NLS and rRNA binding motifs in the L25 ribosomal protein from Leishmania (viannia) braziliensis: investigation of its diagnostic capabilities. Parasitology. 2002 Jul;125(Pt 1):51-7.

6089. Hailu A, Kroon CC, Schoone GJ, Berhe N, Schallig HD, Kager PA. Sero-epidemiological assessment and diagnosis of visceral leishmaniasis in an endemic locality using Fast Agglutination Screening Test (FAST). Acta Trop. 2002 Aug;83(2):93-101.

6090. Qadoumi M, Becker I, Donhauser N, Rollinghoff M, Bogdan C. Expression of inducible nitric oxide synthase in skin lesions of patients with american cutaneous leishmaniasis. Infect Immun. 2002 Aug;70(8):4638-42.

6091. Sundar S, Sahu M, Mehta H, Gupta A, Kohli U, Rai M, Berman JD, Murray HW. Noninvasive management of Indian visceral leishmaniasis: clinical application of diagnosis by K39 antigen strip testing at a kala-azar referral unit. Clin Infect Dis. 2002 Sep 1;35(5):581-6.

Pathogenesis:

6093. Descoteaux A, Turco SJ. Functional aspects of the Leishmania donovani lipophosphoglycan during macrophage infection. Microbes Infect. 2002 Jul;4(9):975-81. Review.

6094. Jappe U. Unusual skin infections in military personnel.Clin Dermatol. 2002 Jul-Aug;20(4):425-34. Review.

6095. Junghae M, Raynes JG. Activation of p38 mitogen-activated protein kinase attenuates Leishmania donovani infection in macrophages. Infect Immun. 2002 Sep;70(9):5026-35.

6096. Pineda JA, Martin-Sanchez J, Macias J, Morillas F. Leishmania spp infection in injecting drug users. Lancet. 2002 Sep 21;360(9337):950-1.

Vaccines:

6097. Schallig HD, Oskam L. Molecular biological applications in the diagnosis and control of leishmaniasis and parasite identification. Trop Med Int Health 2002 Aug;7(8):641-51

Therapy:

6098. Esfandiarpour I, Alavi A. Evaluating the efficacy of allopurinol and meglumine antimoniate (Glucantime) in the treatment of cutaneous leishmaniasis. Int J Dermatol. 2002 Aug;41(8):521-4.

6099. Gilbert IH. Inhibitors of dihydrofolate reductase in Leishmania and trypanosomes. Biochim Biophys Acta. 2002 Jul 18;1587(2-3):249-57. Review.

6100. Paterson R. Miltefosine presents new hope for leishmaniasis patients. Lancet Infect Dis. 2002 Aug;2(8):452.

6101. Zvulunov A, Klaus S, Vardy D. Fluconazole for the treatment of cutaneous leishmaniasis. N Engl J Med. 2002 Aug 1;347(5):370-1; discussion 370-1.

April 2003

6766. Bacellar O, Lessa H, Schriefer A, Machado P, Ribeiro de Jesus A, Dutra WO,Gollob KJ, Carvalho EM.Up-regulation of Th1-type responses in mucosal leishmaniasis patients.Infect Immun 2002 Dec;70(12):6734-40

6767. Bosch RJ, Rodrigo AB, Sanchez P, de Galvez MV, Herrera E. Presence of Leishmania organisms in specific and non-specific skin lesions in HIV-infected individuals with visceral leishmaniasis. Int J Dermatol 2002 Oct;41(10):670-5

Pathogenesis:

6768. Rodrigues EH, Felinto de Brito ME, Mendonca MG, Werkhauser RP, Coutinho EM, Souza WV, Militao de Albuquerque Mde F, Jardim ML, Abath FG. Evaluation of PCR for diagnosis of American cutaneous leishmaniasis in an area of endemicity in northeastern Brazil. J Clin Microbiol 2002 Oct;40(10):3572-6

6769. Vilela RB, Bordin JO, Chiba AK, Castelo A, Barbosa MC. RBC-associated IgG in patients with visceral leishmaniasis (kala-azar): a prospective analysis. Transfusion 2002 Nov;42(11):1442-7

Therapy:

6770. Del Giudice P, Mary-Krause M, Pradier C, Grabar S, Dellamonica P, Marty P, Gastaut JA, Costagliola D, Rosenthal E; French Hospital Database on HIV Clinical Epidemiologic Group. Impact of highly active antiretroviral therapy on the incidence of visceral leishmaniasis in a French cohort of patients infected with human immunodeficiency virus. J Infect Dis 2002 Nov 1;186(9):1366-70

6771. Jacobs S. An oral drug for leishmaniasis. N Engl J Med 2002 Nov 28;347(22):1737-8

July 2003

7285. Amato VS, de Andrade HF, Duarte MI. Mucosal leishmaniasis: in situ characterization of the host inflammatory response, before and after treatment. Acta Trop. 2003 Jan;85(1):39-49.

7286. Haider S, Boutross-Tadross O, Radhi J, Momar N. Cutaneous ulcer in a man returning from Central America. CMAJ. 2003 Mar 4;168(5):590-1.

7287. Lagler H, Willheim M, Traunmuller F, Wahl K, Winkler H, Ramharter M, Graninger W, Winkler S. Cellular profile of cytokine production in a patient with visceral leishmaniasis: gammadelta+ T cells express both type 1 cytokines and interleukin-10. Scand J Immunol. 2003 Mar;57(3):291-5.

7288. Veeken H, Ritmeijer K, Seaman J, Davidson R. Comparison of an rK39 dipstick rapid test with direct agglutination test and splenic aspiration for the diagnosis of kala-azar in Sudan. Trop Med Int Health. 2003 Feb;8(2):164-7.

Pathogenesis:

7289. Belhadj S, Pratlong F, Hammami M, Kallel K, Dedet JP, Chaker E. Human cutaneous leishmaniasis due to Leishmania infantum in the Sidi Bourouis focus (Northern Tunisia): epidemiological study and isoenzymatic characterization of the parasites.Acta Trop. 2003 Jan;85(1):83-6.

Vaccines:

7290. Ahmed S, Colmenares M, Soong L, Goldsmith-Pestana K, Munstermann L, Molina R, McMahon-Pratt D. Intradermal infection model for pathogenesis and vaccine studies of murine visceral leishmaniasis. Infect Immun 2003 Jan;71(1):401-10

Therapy:

7291. Belhadj S, Pratlong F, Hammami M, Kallel K, Dedet JP, Chaker E. Human cutaneous leishmaniasis due to Leishmania infantum in the Sidi Bourouis focus (Northern Tunisia): epidemiological study and isoenzymatic characterization of the parasites. Acta Trop 2003 Jan;85(1):83-6

7292. Mehmet T, Hokelek M. Pneumonia associated with visceral leishmaniasis in childhood. J Trop Pediatr 2003 Feb;49(1):61

7293. Zijlstra EE, Musa AM, Khalil EA, el-Hassan IM, el-Hassan AM. Post-kala-azar dermal leishmaniasis.Lancet Infect Dis 2003 Feb;3(2):87-98

October 2003

8016. Gangneux JP, Menotti J, Lorenzo F, Sarfati C, Blanche H, Bui H, Pratlong F, Garin YJ, Derouin F. Prospective value of PCR amplification and sequencing for diagnosis and typing of old world Leishmania infections in an area of nonendemicity. J Clin Microbiol. 2003 Apr;41(4):1419-22.

8017. Goswami BK, Datta S, Chakrabarti S, Chakrabarti S, Giri A, Debnath NB, Datta K, Bandopadhayay G, Das S. Experience of visceral leishmaniasis in the northern districts of West Bengal � the emerging sodium stibogluconate unrespensiveness. Indian med J 2002, 96 (7), 173-6.

8018. Haseeb AN, el-Shazly AM, Arafa MA, Morsy AT. Evaluation of excretory/secretory Fasciola (Fhes) antigen in diagnosis of human fascioliasis. J Egypt Soc Parasitol. 2003 Apr;33(1):123-38.

8019. Ikonomopoulos J, Kokotas S, Gazouli M, Zavras A, Stoitsiou M, Gorgoulis VG. Molecular diagnosis of leishmaniosis in dogs. Comparative application of traditional diagnostic methods and the proposed assay on clinical samples. Vet Parasitol. 2003 Apr 18;113(2):99-113.

8020. Rahman SB, Bari AU. Laboratory profile in patients of cutaneous leishmaniasis from various regions of Pakistan. J Coll Physicians Surg Pak. 2003 Jun;13(6):313-6.

8021. Reithinger R, Espinoza JC, Courtenay O, Davies CR. Evaluation of PCR as a diagnostic mass-screening tool to detect Leishmania (Viannia) spp. in domestic dogs (Canis familiaris). J Clin Microbiol. 2003 Apr;41(4):1486-93.

8022. Whittemore JC, Salman MD. Think screening unnecessary, unrealistic for all blood donors. J Am Vet Med Assoc. 2003 Jun 1;222(11):1502; author reply 1502.

Pathogenesis:

8023. Bertholet S, Dickensheets HL, Sheikh F, Gam AA, Donnelly RP, Kenney RT. Leishmania donovani-induced expression of suppressor of cytokine signaling 3 in human macrophages: a novel mechanism for intracellular parasite suppression of activation. Infect Immun. 2003 Apr;71(4):2095-101.

8024. Cordeiro-da-Silva A, Cardoso L, Araujo N, Castro H, Tomas A, Rodrigues M, Cabral M, Vergnes B, Sereno D, Ouaissi A. Identification of antibodies to Leishmania silent information regulatory 2 (SIR2) protein homologue during canine natural infections: pathological implications. Immunol Lett. 2003 Apr 3;86(2):155-62.

8025. Lang T, Courret N, Colle JH, Milon G, Antoine JC. The levels and patterns of cytokines produced by CD4 T lymphocytes of BALB/c mice infected with Leishmania major by inoculation into the ear dermis depend on the infectiousness and size of the inoculum. Infect Immun. 2003 May;71(5):2674-83.

8026. Lima VM, Goncalves ME, Ikeda FA, Luvizotto MC, Feitosa MM. Anti-leishmania antibodies in cerebrospinal fluid from dogs with visceral leishmaniasis. Braz J Med Biol Res. 2003 Apr;36(4):485-9. Epub 2003 Apr 08.

8027. Pelletier I, Hashidate T, Urashima T, Nishi N, Nakamura T, Futai M, Arata Y, Kasai K-, Hirashima M, Hirabayashi J, Sato S. Specific recognition of Leishmania major poly-beta-galactosyl epitopes by galectin-9: possible implication of galectin-9 in interaction between L. major and host cells. J Biol Chem. 2003 Jun 20;278(25):22223-30. Epub 2003 Apr 08.

8028. Reithinger R, Espinoza JC, Courtenay O, Davies CR. Evaluation of PCR as a diagnostic mass-screening tool to detect Leishmania (Viannia) spp. in domestic dogs (Canis familiaris). J Clin Microbiol. 2003 Apr;41(4):1486-93.

Therapy:

8029. Carter KC, Sundar S, Spickett C, Pereira OC, Mullen AB. The in vivo susceptibility of Leishmania donovani to sodium stibogluconate is drug specific and can be reversed by inhibiting glutathione biosynthesis. Antimicrob Agents Chemother. 2003 May;47(5):1529-35.

8030. Cauchetier E, Paul M, Rivollet D, Fessi H, Astier A, Deniau M. Therapeutic evaluation of free and nanocapsule-encapsulated atovaquone in the treatment of murine visceral leishmaniasis. Ann Trop Med Parasitol. 2003 Apr;97(3):259-68.

8031. Montero JA, Ruiz-Moreno JM, Sanchis E. Intraretinal hemorrhage associated with leishmaniasis. Ophthalmic Surg Lasers Imaging. 2003 May-Jun;34(3):212-4.

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