Selected abstracts:

1.            Boudina S, Abel ED. Diabetic cardiomyopathy revisited. Circulation. 2007 Jun 26;115(25):3213-23. Review.

Division of Endocrinology, Metabolism and Diabetes and Program in Human Molecular Biology and Genetics, University of Utah School of Medicine, Salt Lake City 84112, USA.

Diabetes mellitus increases the risk of heart failure independently of underlying coronary artery disease, and many believe that diabetes leads to cardiomyopathy. The underlying pathogenesis is partially understood. Several factors may contribute to the development of cardiac dysfunction in the absence of coronary artery disease in diabetes mellitus. This review discusses the latest findings in diabetic humans and in animal models and reviews emerging new mechanisms that may be involved in the development and progression of cardiac dysfunction in diabetes.

2.            Moore SA, Zoellner LA. Overgeneral autobiographical memory and traumatic events: an evaluative review. Psychol Bull. 2007 May;133(3):419-37. 

Department of Psychology, University of Washington, Seattle, WA 98195, USA.

Does trauma exposure impair retrieval of autobiographical memories? Many theorists have suggested that the reduced ability to access specific memories of life events, termed overgenerality, is a protective mechanism helping attenuate painful emotions associated with trauma. The authors addressed this question by reviewing 24 studies that assessed trauma exposure and overgenerality, examining samples with posttraumatic stress disorder, acute stress disorder, depression, traumatic event exposure, and other clinical disorders. Limitations are discussed, including variations in assessment of events, depression, and overgenerality and the need for additional comparison groups. Across studies, there was no consistent association between trauma exposure and overgenerality, suggesting that trauma exposure is unlikely to be the primary mechanism leading to overgenerality. Instead, psychopathology factors such as depression and posttraumatic stress appear to be more consistently associated with overgenerality. Alternative overgenerality theories may help identify key overgenerality mechanisms, improving current understanding of autobiographical memory processes underlying psychopathology. (c) 2007 APA, all rights reserved

3.            Ott CH, Lueger RJ, Kelber ST, Prigerson HG. Spousal bereavement in older adults: common, resilient, and chronic grief with defining characteristics. J Nerv Ment Dis. 2007 Apr;195(4):332-41. 

College of Nursing, University of Wisconsin-Milwaukee, 53201-0413, USA.

The purpose of this study was to identify empirically patterns of grief among 141 older bereaved spouses. A longitudinal hierarchical cluster procedure with the Ward agglomeration method was used to identify distinct clusters based on grief scores. Three clusters were identified: common (49%), resilient (34%), and chronic (17%) grief. Members of the common grief cluster experienced elevated levels of grief and depressive symptoms that decreased over time. Members of the resilient cluster experienced the lowest levels of grief and depression and the highest quality of life. The chronic grief cluster experienced the highest levels of grief and depression, more sudden deaths, the lowest self-esteem, and the highest marital dependency. The majority in this chronic cluster also met proposed criteria for a diagnosis of complicated grief. Five out of every six bereaved spouses adjusted well over time, and about a third of these showed considerable resilience without negative consequences. One out of six experienced a chronic grief syndrome. Early identification of this syndrome can lead to referral to newly emergent treatments specific for grief.

4.            Sareen J, Cox BJ, Stein MB, Afifi TO, Fleet C, Asmundson GJ. Physical and mental comorbidity, disability, and suicidal behavior associated with posttraumatic stress disorder in a large community sample. Psychosom Med. 2007 Apr;69(3):242-8.

Department of Psychiatry, University of Manitoba, Winnipeg, Manitoba, Canada.

OBJECTIVE: To assess if posttraumatic stress disorder (PTSD), recognized as a common mental disorder in the general population and veteran samples, has a unique impact on comorbidity, disability, and suicidal behavior (after adjusting for other mental disorders, especially depression). METHODS: Data came from the Canadian Community Health Survey Cycle 1.2 (n = 36,984; age > or = 15 years; response rate 77%). All respondents were asked if they had been given a diagnosis of PTSD by a healthcare professional. A select number of mental disorders were assessed by the Composite International Diagnostic Interview. Chronic physical health conditions, measures of quality of life, disability, and suicidal behavior were also assessed. RESULTS: The prevalence of PTSD as diagnosed by health professionals was 1.0% (95% CI = 0.90-1.15). After adjusting for sociodemographic factors and other mental disorders, PTSD remained significantly associated with several physical health problems including cardiovascular diseases, respiratory diseases, chronic pain conditions, gastrointestinal illnesses, and cancer. After adjusting for sociodemographic factors, mental disorders, and severity of physical disorders, PTSD was associated with suicide attempts, poor quality of life, and short- and long-term disability. CONCLUSIONS: PTSD was uniquely associated with several physical disorders, disability, and suicidal behavior. Increased early recognition and treatment of PTSD are warranted.

5.            Tiet QQ, Mausbach B. Treatments for patients with dual diagnosis: a review. Alcohol Clin Exp Res. 2007 Apr;31(4):513-36. Review.

Center for Health Care Evaluation, VA Palo Alto Health Care System, Palo Alto, California 94025, USA.

BACKGROUND: Comorbid substance use and mental illness is prevalent and often results in serious consequences. However, little is known about the efficacy of treatments for patients with dual diagnosis. METHODS: This paper reviews both the psychosocial and medication treatments for those diagnosed with a substance-related disorder and one of the following disorders: (a) depression, (b) anxiety disorder, (c) schizophrenia, (d) bipolar disorder, (e) severe mental illness, and (f) nonspecific mental illness. We made no restriction of study design to include all published studies, due to the dearth of studies on treatments of patients with dual diagnosis. RESULTS: Fifty-nine studies were identified (36 randomized-controlled trials; RCT). Limited number of studies, especially RCTs, have been conducted within each comorbid category. This review did not find treatments that had been replicated and consistently showed clear advantages over comparison condition for both substance-related and other psychiatric outcomes. CONCLUSIONS: Although no treatment was identified as efficacious for both psychiatric disorders and substance-related disorder, this review finds: (1) existing efficacious treatments for reducing psychiatric symptoms also tend to work in dual-diagnosis patients, (2) existing efficacious treatments for reducing substance use also decrease substance use in dually diagnosed patients, and (3) the efficacy of integrated treatment is still unclear. This review provides a critique of the current state of the literature, identifies the directions for future research on treatment of dual-diagnosis individuals, and calls for urgent attention by researchers and funding agencies to conduct more and more methodologically rigorous research in this area.

6.            Toneatto T, Nguyen L. Does mindfulness meditation improve anxiety and mood symptoms? A review of the controlled research. Can J Psychiatry. 2007 Apr;52(4):260-6. Review.

Centre for Addiction and Mental Health, Toronto, Ontario.

OBJECTIVE: To review the impact of mindfulness-based stress reduction (MBSR) on symptoms of anxiety and depression in a range of clinical populations. METHOD: Our review included any study that was published in a peer-reviewed journal, used a control group, and reported outcomes related to changes in depression and anxiety. We extracted the following key variables from each of the 15 studies identified: anxiety or depression outcomes after the MBSR program, measurement of compliance with MBSR instructions, type of control group included, type of clinical population studied, and length of follow-up. We also summarized modifications to the MBSR program. RESULTS: Measures of depression and anxiety were included as outcome variables for a broad range of medical and emotional disorders. Evidence for a beneficial effect of MBSR on depression and anxiety was equivocal. When active control groups were used, MBSR did not show an effect on depression and anxiety. Adherence to the MBSR program was infrequently assessed. Where it was assessed, the relation between practising mindfulness and changes in depression and anxiety was equivocal. CONCLUSIONS: MBSR does not have a reliable effect on depression and anxiety.


16548.   Henneberger PK. Work-exacerbated asthma. Curr Opin Allergy Clin Immunol. 2007 Apr;7(2):146-51. Review.

16549.   Hilberg T. Etiology of exercise-induced asthma: physical stress-induced transcription. Curr Allergy Asthma Rep. 2007 Apr;7(1):27-32.

16550.   Ito K, Caramori G, Adcock IM. Therapeutic potential of phosphatidylinositol 3-kinase inhibitors in inflammatory respiratory disease. J Pharmacol Exp Ther. 2007 Apr;321(1):1-8.  

16551.   Weichenthal S, Dufresne A, Infante-Rivard C.  Indoor ultrafine particles and childhood asthma: exploring a potential public health concern. Indoor Air. 2007 Apr;17(2):81-91. Review. 


16552.  Anderson BJ, Haimovici F, Ginsburg ES, Schust DJ, Wayne PM. In vitro fertilization and acupuncture: clinical efficacy and mechanistic basis. Altern Ther Health Med. 2007 May-Jun;13(3):38-48. Review. 

16553.  Beg MR, Casey JE, Saunders CD.  A typology of behavior problems in preschool children. Assessment. 2007 Jun;14(2):111-28. 

16554.  Bomba M, Gambera A, Bonini L, Peroni M, Neri F, Scagliola P, Nacinovich R. Endocrine profiles and neuropsychologic correlates of functional hypothalamic amenorrhea in adolescents. Fertil Steril. 2007 Apr;87(4):876-85.

16555.  Casadesus G, Moreira PI, Nunomura A, Siedlak SL, Bligh-Glover W, Balraj E, Petot G, Smith MA, Perry G. Indices of metabolic dysfunction and oxidative stress. Neurochem Res. 2007 Apr-May;32(4-5):717-22.

16556.  Chrousos GP, Kino T. Glucocorticoid action networks and complex psychiatric and/or somatic disorders. Stress. 2007 Jun;10(2):213-9. Review.

16557.  Davis EP, Glynn LM, Schetter CD, Hobel C, Chicz-Demet A, Sandman CA. Prenatal exposure to maternal depression and cortisol influences infant temperament. J Am Acad Child Adolesc Psychiatry. 2007 Jun;46(6):737-46.

16558.  Derluyn I, Broekaert E. Different perspectives on emotional and behavioural problems in unaccompanied refugee children and adolescents. Ethn Health. 2007 Apr;12(2):141-62.

16559.  Drew MR, Hen R. Adult hippocampal neurogenesis as target for the treatment of depression. CNS Neurol Disord Drug Targets. 2007 Jun;6(3):205-18. Review.

16560.  Gallacher J, Bronstering K, Palmer S, Fone D, Lyons R. Symptomatology attributable to psychological exposure to a chemical incident: a natural experiment. J Epidemiol Community Health. 2007 Jun;61(6):506-12.

16561.  Hawley LL, Ringo Ho MH, Zuroff DC, Blatt SJ. Stress reactivity following brief treatment for depression: differential effects of psychotherapy and medication. J Consult Clin Psychol. 2007 Apr;75(2):244-56.

16562.  Kiecolt-Glaser JK, Belury MA, Porter K, Beversdorf DQ, Lemeshow S, Glaser R. Depressive symptoms, omega-6:omega-3 fatty acids, and inflammation in older adults. Psychosom Med. 2007 Apr;69(3):217-24.

16563.  Kilkkinen A, Kao-Philpot A, O'Neil A, Philpot B, Reddy P, Bunker S, Dunbar J. Prevalence of psychological distress, anxiety and depression in rural communities in Australia. Aust J Rural Health. 2007 Apr;15(2):114-9.

16564.  Kim EY, Miklowitz DJ, Biuckians A, Mullen K. Life stress and the course of early-onset bipolar disorder. J Affect Disord. 2007 Apr;99(1-3):37-44.

16565.   Lopez J, Crespo M, Zarit SH. Assessment of the efficacy of a stress management program for informal caregivers of dependent older adults. Gerontologist. 2007 Apr;47(2):205-14.

16566.  McDevitt-Murphy ME, Weathers FW, Flood AM, Eakin DE, Benson TA. The utility of the PAI and the MMPI-2 for discriminating PTSD, depression, and social phobia in trauma-exposed college students. Assessment. 2007 Jun;14(2):181-95.

16567.  Palesh OG, Collie K, Batiuchok D, Tilston J, Koopman C, Perlis ML, Butler LD, Carlson R, Spiegel D. A longitudinal study of depression, pain, and stress as predictors of sleep disturbance among women with metastatic breast cancer. Biol Psychol. 2007 Apr;75(1):37-44.

16568.  Pandey M, Devi N, Thomas BC, Kumar SV, Krishnan R, Ramdas K. Distress overlaps with anxiety and depression in patients with head and neck cancer. Psychooncology. 2007 Jun;16(6):582-6.

16569.  Repokari L, Punamaki RL, Unkila-Kallio L, Vilska S, Poikkeus P, Sinkkonen J, Almqvist F, Tiitinen A, Tulppala M. Infertility treatment and marital relationships: a 1-year prospective study among successfully treated ART couples and their controls. Hum Reprod. 2007 May;22(5):1481-91.

16570.  Safford SM, Alloy LB, Abramson LY, Crossfield AG. Negative cognitive style as a predictor of negative life events in depression-prone individuals: a test of the stress generation hypothesis. J Affect Disord. 2007 Apr;99(1-3):147-54.

16571.  Salcioglu E, Basoglu M, Livanou M. Post-traumatic stress disorder and comorbid depression among survivors of the 1999 earthquake in Turkey. Disasters. 2007 Jun;31(2):115-29.

16572.  Salisbury AL, Lester BM, Seifer R, Lagasse L, Bauer CR, Shankaran S, Bada H, Wright L, Liu J, Poole K. Prenatal cocaine use and maternal depression: effects on infant neurobehavior. Neurotoxicol Teratol. 2007 May-Jun;29(3):331-40.

16573.  Streeter CC, Jensen JE, Perlmutter RM, Cabral HJ, Tian H, Terhune DB, Ciraulo DA, Renshaw PF. Yoga Asana sessions increase brain GABA levels: a pilot study. J Altern Complement Med. 2007 May;13(4):419-26.

16574.  Tam WH, Chung T. Psychosomatic disorders in pregnancy. Curr Opin Obstet Gynecol. 2007 Apr;19(2):126-32. Review.

16575.  Tanner JL, Reinherz HZ, Beardslee WR, Fitzmaurice GM, Leis JA, Berger SR. Change in prevalence of psychiatric disorders from ages 21 to 30 in a community sample. J Nerv Ment Dis. 2007 Apr;195(4):298-306.

16576.  Tol WA, Komproe IH, Thapa SB, Jordans MJ, Sharma B, De Jong JT. Disability associated with psychiatric symptoms among torture survivors in rural Nepal. J Nerv Ment Dis. 2007 Jun;195(6):463-9.

Heart Disease:

16577.  Belardinelli R. Exercise training in chronic heart failure: how to harmonize oxidative stress, sympathetic outflow, and angiotensin II. Circulation. 2007 Jun 19;115(24):3042-4.

16578.  Bose KS, Agrawal BK. Effect of lycopene from cooked tomatoes on serum antioxidant enzymes, lipid peroxidation rate and lipid profile in coronary heart disease. Singapore Med J. 2007 May;48(5):415-20.

16579.  Campolo J, De Maria R, Caruso R, Accinni R, Turazza F, Parolini M, Roubina E, De Chiara B, Cighetti G, Frigerio M, Vitali E, Parodi O. Blood glutathione as independent marker of lipid peroxidation in heart failure. Int J Cardiol. 2007 Apr 12;117(1):45-50.

16580.  From AM, Hyder JA, Kearns AM, Bailey KR, Pellikka PA. Relationship between low bone mineral density and exercise-induced myocardial ischemia. Mayo Clin Proc. 2007 Jun;82(6):679-85.

16581.  Jahnke C, Nagel E, Gebker R, Kokocinski T, Kelle S, Manka R, Fleck E, Paetsch I. Prognostic value of cardiac magnetic resonance stress tests: adenosine stress perfusion and dobutamine stress wall motion imaging. Circulation. 2007 Apr 3;115(13):1769-76.

16582.  Lewis W, Day BJ, Kohler JJ, Hosseini SH, Chan SS, Green EC, Haase CP, Keebaugh ES, Long R, Ludaway T, Russ R, Steltzer J, Tioleco N, Santoianni R, Copeland WC. Decreased mtDNA, oxidative stress, cardiomyopathy, and death from transgenic cardiac targeted human mutant polymerase gamma. Lab Invest. 2007 Apr;87(4):326-35.

16583.  Lipovetzky N, Hod H, Roth A, Kishon Y, Sclarovsky S, Green MS. Emotional events and anger at the workplace as triggers for a first event of the acute coronary syndrome: a case-crossover study. Isr Med Assoc J. 2007 Apr;9(4):310-5.

16584.  Luptak I, Shen M, He H, Hirshman MF, Musi N, Goodyear LJ, Yan J, Wakimoto H, Morita H, Arad M, Seidman CE, Seidman JG, Ingwall JS, Balschi JA, Tian R.  Aberrant activation of AMP-activated protein kinase remodels metabolic network in favor of cardiac glycogen storage. J Clin Invest. 2007 May;117(5):1432-9.

16585.  McNulty PH, Robertson BJ, Tulli MA, Hess J, Harach LA, Scott S, Sinoway LI. Effect of hyperoxia and vitamin C on coronary blood flow in patients with ischemic heart disease. J Appl Physiol. 2007 May;102(5):2040-5.

16586.  Miyazaki A, Adachi H, Oshima S, Taniguchi K, Hasegawa A, Kurabayashi M. Blood flow redistribution during exercise contributes to exercise tolerance in patients with chronic heart failure. Circ J. 2007 Apr;71(4):465-70.

16587.  Pierard LA, Lancellotti P. Stress testing in value disease. Heart. 2007 Jun;93(6):766-72.

16588.  Rankin JW, Turpyn AD. Low carbohydrate, high fat diet increases C-reactive protein during weight loss. J Am Coll Nutr. 2007 Apr;26(2):163-9.

16589.  Schmid JP, Noveanu M, Morger C, Gaillet R, Capoferri M, Anderegg M, Saner H. Influence of water immersion, water gymnastics and swimming on cardiac output in patients with heart failure. Heart. 2007 Jun;93(6):722-7.

16590.  Singh U, Devaraj S, Jialal I. Coenzyme Q10 supplementation and heart failure. Nutr Rev. 2007 Jun;65(6 Pt 1):286-93. Review.

16591.  Soudarssanane MB, Karthigeyan M, Mahalakshmy T, Sahai A, Srinivasan S, Subba Rao KS, Balachander J. Rheumatic fever and rheumatic heart disease: primary prevention is the cost effective option. Indian J Pediatr. 2007 Jun;74(6):567-70. Review.


16592.  Abraham NG, Asija A, Drummond G, Peterson S. Heme oxygenase -1 gene therapy: recent advances and therapeutic applications. Curr Gene Ther. 2007 Apr;7(2):89-108. Review.

16593.  Aggeli C, Christoforatou E, Giannopoulos G, Roussakis G, Kokkinakis C, Barbetseas J, Vlachopoulos C, Stefanadis C. The diagnostic value of adenosine stress-contrast echocardiography for diagnosis of coronary artery disease in hypertensive patients: comparison to Tl-201 single-photon emission computed tomography. Am J Hypertens. 2007 May;20(5):533-8.

16594.  Barden A, Zilkens RR, Croft K, Mori T, Burke V, Beilin LJ, Puddey IB. A reduction in alcohol consumption is associated with reduced plasma F2-isoprostanes and urinary 20-HETE excretion in men. Free Radic Biol Med. 2007 Jun 1;42(11):1730-5.

16595.  Beydoun MA, Kaufman JS, Satia JA, Rosamond W, Folsom AR. Plasma n-3 fatty acids and the risk of cognitive decline in older adults: the Atherosclerosis Risk in Communities Study. Am J Clin Nutr. 2007 Apr;85(4):1103-11. 

16596.  Chrysohoou C, Panagiotakos DB, Pitsavos C, Skoumas J, Economou M, Papadimitriou L, Stefanadis C. The association between pre-hypertension status and oxidative stress markers related to atherosclerotic disease: the ATTICA study. Atherosclerosis. 2007 May;192(1):169-76.

16597.  Cindrova-Davies T, Spasic-Boskovic O, Jauniaux E, Charnock-Jones DS, Burton GJ. Nuclear factor-kappa B, p38, and stress-activated protein kinase mitogen-activated protein kinase signaling pathways regulate proinflammatory cytokines and apoptosis in human placental explants in response to oxidative stress: effects of antioxidant vitamins. Am J Pathol. 2007 May;170(5):1511-20.

16598.  Cudmore M, Ahmad S, Al-Ani B, Fujisawa T, Coxall H, Chudasama K, Devey LR, Wigmore SJ, Abbas A, Hewett PW, Ahmed A. Negative regulation of soluble Flt-1 and soluble endoglin release by heme oxygenase-1. Circulation. 2007 Apr 3;115(13):1789-97.

16599.  Dandona P, Ghanim H, Brooks DP. Antioxidant activity of carvedilol in cardiovascular disease. J Hypertens. 2007 Apr;25(4):731-41. Review.

16600.  Goette A, Bukowska A, Lendeckel U. Non-ion channel blockers as anti-arrhythmic drugs (reversal of structural remodeling). Curr Opin Pharmacol. 2007 Apr;7(2):219-24.

16601.  Husain K. Vascular endothelial oxidative stress in alcohol-induced hypertension. Cell Mol Biol (Noisy-le-grand). 2007 Apr 15;53(1):70-7.

16602.  Maki KC, Galant R, Samuel P, Tesser J, Witchger MS, Ribaya-Mercado JD, Blumberg JB, Geohas J. Effects of consuming foods containing oat beta-glucan on blood pressure, carbohydrate metabolism and biomarkers of oxidative stress in men and women with elevated blood pressure. Eur J Clin Nutr. 2007 Jun;61(6):786-95.

16603.  Meier P, Rossert J, Plouin PF, Burnier M. Atherosclerotic renovascular disease: beyond the renal artery stenosis. Nephrol Dial Transplant. 2007 Apr;22(4):1002-6. 

16604.  Moyad MA, Merrick GS. Cholesterol, cholesterol-lowering agents/statins, and urologic disease: Part VI--The recent rise and fall of the HDL-boosting drug torceptrapib. Urol Nurs. 2007 Apr;27(2):169-73.

16605.  Stauss HM. Identification of blood pressure control mechanisms by power spectral analysis. Clin Exp Pharmacol Physiol. 2007 Apr;34(4):362-8. Review.

16606.  Surtees PG, Wainwright NW, Luben RL, Wareham NJ, Bingham SA, Khaw KT. Adaptation to social adversity is associated with stroke incidence: evidence from the EPIC-Norfolk prospective cohort study. Stroke. 2007 May;38(5):1447-53.