DIARRHOEA

Selected abstract:

1.            Mera V, Lopez T, Serralta J. Take traveller's diarrhoea to heart. Travel Med Infect Dis. 2007 May;5(3):202-3. 

ClĂ­nica Benidorm, Internal Medicine, Av Alfonso Puchades, 8, 03500 Benidorm, Alicante, Spain. v.mera@telefonica.net

Diarrhoea is a common health problem among travellers worldwide. We focus attention on the recognition of the postinfectious complications of traveller's diarrhoea. An English traveller, aged 43, attended a hospital in Benidorm (Spain) complaining of chest pain. A week previously, fever and severe diarrhoea were present. The electrocardiogram and cardiac enzymes were not normal. The coproculture yielded Campylobacter jejunii. Acute myocarditis can be an exceptional complication of gastroenteritis masquerading as acute myocardial infarction or leading to congestive heart failure.

2.            Oishi K, Saito M, Mapua CA, Natividad FF. Dengue illness: clinical features and pathogenesis. J Infect Chemother. 2007 Jun;13(3):125-33. 

Department of Special Pathogens, International Research Center for Infectious Diseases, Research Institute for Microbial Diseases, Osaka University, 3-1 Yamadaoka, Suita, Osaka 565-0871, Japan. oishik@biken.osaka-u.ac.jp

The incidence and geographical distribution of dengue has gradually increased during the past decade. This review is an update on dengue virus infections, based on our clinical and laboratory experiences in the Philippines and on other relevant literature. The differential diagnosis of this disease is discussed, especially for use by clinicians where dengue is not endemic. The complex pathogenesis of thrombocytopenia and increased vascular permeability in dengue illness is also discussed. Our recent data suggest that platelet-associated immunoglobulins involving anti-dengue virus activity play a pivotal role in the development of dengue hemorrhagic fever (DHF), as well as thrombocytopenia in secondary dengue virus infections. Further elucidation is needed on the involvement of platelet-associated immunoglobulins on the molecular mechanisms of thrombocytopenia and the increased vascular permeability.

Diagnosis, Diagnostics, Immunodiagnosis & Immunodiagnostics:

16328.  Chisti MJ, Hossain MI, Malek MA, Faruque AS, Ahmed T, Salam MA. Characteristics of severely malnourished under-five children hospitalized with diarrhoea, and their policy implications. Acta Paediatr. 2007 May;96(5):693-6.

Vaccines:

16329.  Grassly NC, Wenger J, Durrani S, Bahl S, Deshpande JM, Sutter RW, Heymann DL, Aylward RB. Protective efficacy of a monovalent oral type 1 poliovirus vaccine: a case-control study. Lancet. 2007 Apr 21;369(9570):1356-62.

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