TYPHOID  

Some Selected Abstracts:

1.

Boucrot E, Henry T, Borg JP, Gorvel JP, Meresse S.The intracellular fate of Salmonella depends on the recruitment of kinesin. Science. 2005 May 20;308(5725):1174-8

Centre d'Immunologie de Marseille-Luminy, CNRS-INSERM-Universite de la Mediterranee, Parc Scientifique de Luminy, Case 906-13288 Marseille Cedex 9, France.

Salmonella enterica causes a variety of diseases, including gastroenteritis and typhoid fever. The success of this pathogen depends on its capacity to proliferate within host cells in a membrane-bound compartment. We found that the Salmonella-containing vacuole recruited the plus-end-directed motor kinesin. Bacterial effector proteins translocated into the host cell by a type III secretion system antagonistically regulated this event. Among these effectors, SifA targeted SKIP, a host protein that down-regulated the recruitment of kinesin on the bacterial vacuole and, in turn, controlled vacuolar membrane dynamics.

Pathogenesis:

13012.   Akinyemi KO, Smith SI, Oyefolu AO, Coker AO. Multidrug resistance in Salmonella enterica serovar typhi isolated from patients with typhoid fever complications in Lagos, Nigeria. Public Health. 2005 Apr;119(4):321-7.

13013.   Boucrot E, Henry T, Borg JP, Gorvel JP, Meresse S. The intracellular fate of Salmonella depends on the recruitment of  kinesin. Science. 2005 May 20;308(5725):1174-8.

13014.   Dutta S, Sur D, Manna B, Bhattacharya SK, Deen JL, Clemens JD. Rollback of Salmonella enterica serotype Typhi resistance to  chloramphenicol and other antimicrobials in Kolkata, India. Antimicrob Agents Chemother. 2005 Apr;49(4):1662-3.

13015.   McConnell J. Problem pathogens. Lancet Infect Dis. 2005 Jun;5(6):329.

Vaccines:

13016.    DeRoeck D, Clemens JD, Nyamete A, Mahoney RT. Policymakers' views regarding the introduction of new-generation  vaccines against typhoid fever, shigellosis and cholera in Asia. Vaccine. 2005 Apr 15;23(21):2762-74.
Therapy:

13017.    Achla P, Grover SS, Bhatia R, Khare S. Sensitivity index of antimicrobial agents as a simple solution for multidrug resistance in salmonella typhi. Indian Journal of Medical Research. 2005 Mar; 121(3): 185-193.

13018.   Walton MK, Connolly CA. A look back: nursing care of typhoid fever: the pivotal role of nurses at the Children's Hospital of Philadelphia between 1895 and 1910: how the past informs the present. Am J Nurs. 2005 Apr;105(4):74-8.

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