ALLERGY

Some Selected Abstracts:

1.

Aversano M, Caiazzo P, Iorio G, Ponticiello L, Lagana B, Leccese F. Improvement of chronic idiopathic urticaria with L-thyroxine: a new TSH role in immune response? Allergy. 2005 Apr;60(4):489-93.

Endocrinology Unit ASL NA3, Naples, Italy.

BACKGROUND: The association between chronic idiopathic urticaria (CIU) and autoimmune thyroiditis (AT) is known, as well as major prevalence of antithyroid antibodies in the allergical subjects and other autoimmune diseases. We have evaluated the effects of l-thyroxine on clinical symptoms of CIU in AT patients suggesting the hypothesis of a new thyroid-stimulating hormone (TSH) role in immune system. METHODS: In 20 female patients with CIU + AT, both hypothyroid and euthyroid, we have investigated the therapeutic effects of l-thyroxine dosed to suppress the TSH. Free-T3, Free-T4, TSH, antithyroperoxidase and antithyroglobulin antibodies, total immunoglobulin (Ig)E, Rheuma test and eritro-sedimentation rate were monitored during treatment. Results: In 16 patients a strong decrease of urticaria symptoms has happened after 12 weeks. The TPO Ab and HTG Ab clearly decreased in 14 patients. Furthermore, in two patients with rheumatoid arthritis and in two patients with pollen allergy a strong decrease of rheuma test titer and total IgE has happened. Conclusion: The reason of AT is associated to CIU and others allergical and autoimmune diseases is poorly known. The exclusive hormonal therapy reduces the symptoms of CIU and inflammatory response in many chronic diseases associated to AT. We suggest a stimulatory effect of TSH able to produce considerable changes of the immune response and immune tolerance in patients with AT causing target organs damage. The causal mechanism involves immune, nervous and endocrine system, sharing a common set of hormones, cytokines and receptors, in a unique totally integrated loop (the neuro-immuno-endocrine axis).

2.

Bircher AJ. Symptoms and danger signs in acute drug hypersensitivity. Toxicology. 2005 Apr 15;209(2):201-7.

Allergy Unit, Department of Dermatology, University Hospital Basel, Petersgraben 4, CH-4031 Basel, Switzerland. andreas.bircher@unibas.ch

Early and rapid recognition of severe adverse drug reactions is essential. Prompt withdrawal of the offending drug is the most important action to minimize morbidity and mortality. Dependent on the type of reaction, e.g. in immediate type reactions instant withdrawal and therapy are mandatory, whereas in delayed reactions diagnosis as early as possible may be life-saving. The skin is an important herald organ and may early signal a severe evolution of a cutaneous reaction or involvement of circulating blood cells or internal organs. A synthesis considering all factors should be made to obtain an early and correct diagnosis.

3.

Bryant R. Asthma in the pediatric sickle cell patient with acute chest syndrome. J Pediatr Health Care. 2005 May-Jun;19(3):157-62.

Texas Children's Hospital, Baylor College of Medicine, Houston, Texas, USA. rxbryant@texaschildrenshospital.org

INTRODUCTION: Acute chest syndrome (ACS) is a potential life-threatening complication of sickle cell disease (SCD). The purpose of this study was to identify the frequency of asthma in children with SCD who were diagnosed with ACS. The objective was to determine if an increased frequency of asthma exists in children with SCD and ACS. METHOD: A retrospective descriptive chart review covering the period from June 1997 to June 2002 was conducted on 60 children ranging in age from 1.5 years to 17 years who had SCD and ACS. Cross-tabs analysis and student t tests were used to determine the significance of the occurrence of asthma in children in whom ACS developed. RESULTS: Of the 60 eligible children with SCD, 53% (32/60) had asthma and/or abnormal pulmonary function tests prior to the development of ACS. DISCUSSION: This is the first study to report a slight increase in the frequency of asthma prior to the initial ACS in children with SCD. The small convenience sample size from one center may have been a limitation in this study to detect significant differences between the variables.

4.

Govindarajan G, Bashir Q, Kuppuswamy S, Brooks C. Sweet syndrome associated with furosemide. South Med J. 2005 May;98(5):570-2.

University of Missouri Health Science Center, Department of Internal Medicine, MA 406, One Hospital Drive, Columbia, MO 65212, USA. govindarajang@health.missouri.edu

This case report describes a case of Sweet syndrome (SS) related to use of furosemide in a 46-year-old female who was admitted for treatment of congestive heart failure. Three days after administration of furosemide, the patient had a fever and a skin eruption appeared on her wrists, forearms, and legs. Biopsy of the skin lesion was consistent with SS. Infection was thought to be unlikely because of negative blood cultures, echocardiography, and other imaging studies. Careful review of her medications revealed that the patient received furosemide before the appearance of the skin eruption and fever. After discontinuation of furosemide, the patient's skin lesion and fever resolved. A MEDLINE search from June 1966 to May 2004 revealed only one reference documenting the association of SS with furosemide administration. Patients who have development of SS without an obvious cause should have their medication list closely reviewed.

5.

Janse AJ, Sinnema G, Uiterwaal CS, Kimpen JL, Gemke RJ. Quality of life in chronic illness: perceptions of parents and paediatricians. Arch Dis Child. 2005 May;90(5):486-91.

Department of Paediatrics, Wilhelmina Children's Hospital, University Medical Centre Utrecht, Netherlands.

AIMS: To investigate the differences in perception of quality of life between parents of chronically ill children and paediatricians at diagnosis and follow up. Quality of life was assessed using the (HUI3). METHODS: Longitudinal study (July 1999-January 2002) of 37 paediatricians and 181 parents of patients (children aged 1-17 years) with cystic fibrosis admitted for a pneumonia or patients with newly diagnosed acute lymphatic leukaemia, juvenile idiopathic arthritis, or asthma. Main outcome measure was percentage agreement on the attributes of the HUI3 between parents and paediatricians. RESULTS: Differences in perception of health and wellbeing between paediatricians and parents of children with a chronic disease were found, not only at diagnosis but also after a period of follow up. Differences were particularly clear in the subjective attributes emotion (range of agreement 28-68%) and pain/discomfort (range of agreement 11-33%). In all patient groups, at baseline and follow up, the paediatrician assessed the patient to have less pain/discomfort in comparison to the parents. Despite a prolonged patient- paediatrician relationship, differences at follow up did not decrease compared to baseline. CONCLUSION: At the onset of a chronic disease, but also after a period of follow up, quality of life of paediatric patients may be misunderstood by healthcare professionals, especially in the subjective attributes. Systematic assessment of quality of life may contribute to better understanding between physicians and parents.

6.

Letko E, Papaliodis DN, Papaliodis GN, Daoud YJ, Ahmed AR, Foster CS. Stevens-Johnson syndrome and toxic epidermal necrolysis: a review of the literature. Ann Allergy Asthma Immunol. 2005 Apr;94(4):419-36; quiz 436-8, 456.

Department of Ophthalmology, Uveitis and Immunology Service, The Massachusetts Eye and Ear Infirmary, Harvard Medical School, Boston, Massachusetts 02114, USA.

OBJECTIVE: To perform a comprehensive review of Stevens-Johnson syndrome and toxic epidermal necrolysis. DATA SOURCES: A MEDLINE search was performed for the years 1975 to 2003 using the keywords Stevens-Johnson syndrome and toxic epidermal necrolysis to identify relevant articles published in English in peer-reviewed journals. STUDY SELECTION: All clinical studies that reported on 4 or more patients, review articles, and experimental studies that concerned disease mechanisms were selected and further analyzed. Clinical reports that included fewer than 4 patients were selected only if they were believed to carry a significant message about disease mechanism or therapy. RESULTS: Stevens-Johnson syndrome and toxic epidermal necrolysis seem to be variants of the same disease with differing severities. A widely accepted consensus regarding diagnostic criteria and therapy does not exist at present. Despite the recent experimental studies, the pathogenic mechanisms of these diseases remain unknown. Although progress in survival through early hospitalization in specialized burn units has been made, the prevalence of life-long disability from the ocular morbidity of Stevens-Johnson syndrome and toxic epidermal necrolysis has remained unchanged for the past 35 years. Further progress depends on modification of the acute phase of the disease rather than continuation of supportive care. The available published evidence indicates that a principal problem in the pathogenesis is immunologic and that immunomodulatory intervention with short-term, high-dose intravenous steroids or intravenous immunoglobulin holds the most promise for effective change in survival and long-term morbidity. CONCLUSIONS: The results of this review call for a widely accepted consensus on diagnostic criteria for Stevens-Johnson and toxic epidermal necrolysis and multicenter collaboration in experimental studies and clinical trials that investigate disease mechanisms and novel therapeutic interventions, respectively.

7.

Peacock ME, Park DS, Swiec GD, Erley KJ. Perioral angioedema associated with angiotensin-converting enzyme inhibitor. J Periodontol. 2005 Apr;76(4):651-4.

U.S. Army, Landstuhl, Germany. mark.peacock@lnd.amedd.army.mil

BACKGROUND: Angioedema is a non-pruritic swelling usually limited to the skin and mucous membranes of the face and perioral soft tissues. It can be life threatening but usually is not, and can be managed with conservative medical treatment unless the airway is endangered. Recent reports suggest that angiotensin-converting enzyme (ACE) inhibitors can predispose and/or precipitate angioedema, with a predilection toward patients of African American ancestry. METHODS: This case report involved a 65-year-old African American female who was being treated surgically for localized chronic periodontitis. The procedure was performed without incident, and the patient was alert and stable when released. The next day, the patient called and reported that her lips were swollen. She stated that this had happened a number of times over the past several years, sometimes related to eating shellfish and other times without any known precipitating factor. All previous episodes of perioral swelling occurred after ACE inhibitor therapy had been initiated. RESULTS: The patient was in no distress, with no other site involvement. She was prescribed oral hydroxyzine and her appearance returned to normal after 5 days. Although the patient had experienced previous episodes of angioedema, none had been in response to any dental procedure. She was referred to the Allergy and Immunology Clinic for skin testing, the results of which were negative to shellfish with good controls. Other potentiating etiologies were also ruled out by the allergist. CONCLUSIONS: Angioedema is a recognized possible side effect of ACE inhibitor therapy. The exact mechanism by which ACE inhibitors induce angioedema is not known, although the risk of occurrence is much greater in African Americans. Practitioners should be alert to this potentially fatal condition in patients who take ACE inhibitors or the newer angiotensin II receptor blockers (ARBs).

8.

Plotkin SA. Vaccines: past, present and future. Nat Med. 2005 Apr;11(4 Suppl):S5-11.

Sanofi Pasteur and the University of Pennsylvania, 4650 Wismer Road, Doylestown, Pennsylvania 18901, USA. Stanley.Plotkin@sanofipasteur.com

The vaccines developed over the first two hundred years since Jenner's lifetime have accomplished striking reductions of infection and disease wherever applied. Pasteur's early approaches to vaccine development, attenuation and inactivation, are even now the two poles of vaccine technology. Today, purification of microbial elements, genetic engineering and improved knowledge of immune protection allow direct creation of attenuated mutants, expression of vaccine proteins in live vectors, purification and even synthesis of microbial antigens, and induction of a variety of immune responses through manipulation of DNA, RNA, proteins and polysaccharides. Both noninfectious and infectious diseases are now within the realm of vaccinology. The profusion of new vaccines enables new populations to be targeted for vaccination, and requires the development of routes of administration additional to injection. With all this come new problems in the production, regulation and distribution of vaccines.

9.

Sabina AB, Williams AL, Wall HK, Bansal S, Chupp G, Katz DL. Yoga intervention for adults with mild-to-moderate asthma: a pilot study. Ann Allergy Asthma Immunol. 2005 May;94(5):543-8.

Yale-Griffin Prevention Research Center, Derby, Connecticut 06418, USA.

BACKGROUND: Preliminary studies investigating yoga and breath work for treating asthma have been promising. Several randomized controlled trials have shown a benefit from yoga postures and breathing vs control, but the control in these cases involved no intervention other than usual care. This study advances the field by providing an active control. OBJECTIVE: To determine the effectiveness and feasibility of a yoga and breath work intervention for improving clinical indices and quality of life in adults with mild-to-moderate asthma. METHODS: A randomized, controlled, double-masked clinical trial was conducted between October 1, 2001, and March 31, 2003. Random assignment was made to either a 4-week yoga intervention that included postures and breath work or a stretching control condition. Outcome measures were evaluated at 4, 8, 12, and 16 weeks and included the Mini Asthma Quality of Life Questionnaire, rescue inhaler use, spirometry, symptom diaries, and health care utilization. RESULTS: Sixty-two participants were randomized to the intervention and control groups, and 45 completed the final follow-up measures. Intention-to-treat analysis was performed. Significant within-group differences in postbronchodilator forced expiratory volume in 1 second and morning symptom scores were apparent in both groups at 4 and 16 weeks; however, no significant differences between groups were observed on any outcome measures. CONCLUSIONS: Iyengar yoga conferred no appreciable benefit in mild-to-moderate asthma. Circumstances under which yoga is of benefit in asthma management, if any, remain to be determined.

Diagnosis, Diagnostics, Immunodiagnosis & Immunodiagnostics:

12411.     Agterof MJ, Biesma DH.  Images in clinical Medicine. Bortezomib-induced skin lesions. N Engl J Med. 2005 Jun 16;352(24):2534.

12412.     Ahmed T, Vaezi MF. The role of pH monitoring in extraesophageal gastroesophageal reflux disease. Gastrointest Endosc Clin N Am. 2005 Apr;15(2):319-31. Review.

12413.     Alobid I, Benitez P, Bernal-Sprekelsen M, Roca J, Alonso J, Picado C, Mullol J. Nasal polyposis and its impact on quality of life: comparison between the effects of medical and surgical treatments. Allergy. 2005 Apr;60(4):452-8.

12414.     American Academy of Family Physicians. Information from your family doctor. Treating my child's asthma. Am Fam Physician. 2005 May 15;71(10):1969.

12415.     Aversano M, Caiazzo P, Iorio G, Ponticiello L, Lagana B, Leccese F. Improvement of chronic idiopathic urticaria with L-thyroxine: a new TSH role in immune response? Allergy. 2005 Apr;60(4):489-93. 

12416.     Baydur A.  Not all that comes out is hot air. Chest. 2005 May;127(5):1482-5.

12417.     Bergeron C, Boulet LP, Hamid Q. Obesity, allergy and immunology. J Allergy Clin Immunol. 2005 May;115(5):1102-4. Review.

12418.     Berkman N, Avital A, Breuer R, Bardach E, Springer C, Godfrey S. Exhaled nitric oxide in the diagnosis of asthma: comparison with bronchial provocation tests. Thorax. 2005 May;60(5):383-8. 

12419.     Beuther DA, Sutherland ER. Obesity and pulmonary function testing. J Allergy Clin Immunol. 2005 May;115(5):1100-1.

12420.     Bircher AJ. Symptoms and danger signs in acute drug hypersensitivity. Toxicology. 2005 Apr 15;209(2):201-7. Review.

12421.     Bischoff S, Crowe SE.  Gastrointestinal food allergy: new insights into pathophysiology and clinical perspectives. Gastroenterology. 2005 Apr;128(4):1089-113. Review. 

12422.     Boushey HA, Sorkness CA, King TS, Sullivan SD, Fahy JV, Lazarus SC, Chinchilli VM, Craig TJ, Dimango EA, Deykin A, Fagan JK, Fish JE, Ford JG, Kraft M, Lemanske RF Jr, Leone FT, Martin RJ, Mauger EA, Pesola GR, Peters SP, Rollings NJ, Szefler SJ, Wechsler ME, Israel E; National Heart, Lung, and Blood Institute's Asthma Clinical Research Network.  Daily versus as-needed corticosteroids for mild persistent asthma. N Engl J Med. 2005 Apr 14;352(15):1519-28. 

12423.     Bousquet PJ, Co-Minh HB, Demoly P. Isolated urticaria to ondansetron and successful treatment with granisetron. Allergy. 2005 Apr;60(4):543-4.

12424.     Brockow K. Contrast media hypersensitivity--scope of the problem. Toxicology. 2005 Apr 15;209(2):189-92. Review.

12425.     Bruce C, Thomas PS. The effect of marimastat, a metalloprotease inhibitor, on allergen-induced asthmatic hyper-reactivity. Toxicol Appl Pharmacol. 2005 Jun 1;205(2):126-32.

12426.     Bryant R. Asthma in the pediatric sickle cell patient with acute chest syndrome. J Pediatr Health Care. 2005 May-Jun;19(3):157-62.

12427.     Chen MJ, Wang TE, Chang WH, Tsai SJ, Liao WS. Endoscopic findings in a patient with Henoch-Schonlein purpura. World J Gastroenterol. 2005 Apr 21;11(15):2354-6. 

12428.     Chhabra SK.  Premenstrual asthma. Indian J Chest Dis Allied Sci. 2005 Apr-Jun;47(2):109-16. Review.

12429.     Chhabra SK. Guidelines for management of asthma: the gaps between theory and practice. Indian J Chest Dis Allied Sci. 2005 Apr-Jun;47(2):77-80.

12430.     Chuchalin A, Kasl M, Bengtsson T, Nihlen U, Rosenborg J. Formoterol used as needed in patients with intermittent or mild persistent asthma. Respir Med. 2005 Apr;99(4):461-70.

12431.     Corry DB. Resolving a case of split personality. Nat Immunol. 2005 May;6(5):432-4.

12432.     Courtney AU, McCarter DF, Pollart SM.  Childhood asthma: treatment update. Am Fam Physician. 2005 May 15;71(10):1959-68. Review.

12433.     Covar RA, Cool C, Szefler SJ. Progression of asthma in childhood. J Allergy Clin Immunol. 2005 Apr;115(4):700-7.

12434.     Demoly P.  Anaphylactic reactions--value of skin and provocation tests. Toxicology. 2005 Apr 15;209(2):221-3.

12435.     Forastiere F, Sunyer J, Farchi S, Corbo G, Pistelli R, Baldacci S, Simoni M, Agabiti N, Perucci CA, Viegi G. Number of offspring and maternal allergy. Allergy. 2005 Apr;60(4):510-4.

12436.     Freiman A. Dermacase. Henoch-Schonlein purpura. Can Fam Physician. 2005 Apr;51:511-2. Review.

12437.     Gaston B.  Inhaled corticosteroid dose reduction in childhood asthma: is nitrosopnea informative? Am J Respir Crit Care Med. 2005 May 15;171(10):1065-6.

12438.     Govindarajan G, Bashir Q, Kuppuswamy S, Brooks C. Sweet syndrome associated with furosemide. South Med J. 2005 May;98(5):570-2. Review. 

12439.     Harboe T, Guttormsen AB, Irgens A, Dybendal T, Florvaag E. Anaphylaxis during anesthesia in Norway: a 6-year single-center follow-up study. Anesthesiology. 2005 May;102(5):897-903.

12440.     Hehn J, Brocker EB, Goebeler M.  Angioedema, eosinophilia, and fever. Arch Dermatol. 2005 May;141(5):633-8.

12441.     High WA, Hoang MP, Miller MD. Pruritic urticarial papules and plaques of pregnancy with unusual and extensive palmoplantar involvement. Obstet Gynecol. 2005 May;105(5 Pt 2):1261-4.

12442.     Hoffmann-Sommergruber K; SAFE consortium. The SAFE project: 'plant food allergies: field to table strategies for reducing their incidence in Europe' an EC-funded study. Allergy. 2005 Apr;60(4):436-42. Review.

12443.     Holten KB; American Academy of Dermatology. How should we care for atopic dermatitis? J Fam Pract. 2005 May;54(5):426-7.

12444.     Janse AJ, Sinnema G, Uiterwaal CS, Kimpen JL, Gemke RJ. Quality of life in chronic illness: perceptions of parents and paediatricians. Arch Dis Child. 2005 May;90(5):486-91.

12445.     Kaur C, Bansal SK, Chhabra SK. Study on serum and urinary cortisol levels of asthmatic patients after treatment with high dose inhaled beclomethasone dipropionate or budesonide. Indian J Chest Dis Allied Sci. 2005 Apr-Jun;47(2):89-95.

12446.     Kimura A, Yoshino H, Yuasa T. Chronic inflammatory demyelinating polyneuropathy in a patient with hyperIgEaemia. J Neurol Sci. 2005 Apr 15;231(1-2):89-93.

12447.     Komericki P, Fellner P, El-Shabrawi Y, Ardjomand N. Keratopathy after ultraviolet B phototherapy. Wien Klin Wochenschr. 2005 Apr;117(7-8):300-2. 

12448.     Korzenik JR. Past and current theories of etiology of IBD: toothpaste, worms, and refrigerators. J Clin Gastroenterol. 2005 Apr;39(4 Suppl 2):S59-65. Review.

12449.     Laroche D. Immediate reactions to contrast media: mediator release and value of diagnostic testing. Toxicology. 2005 Apr 15;209(2):193-4. Review. 

12450.     Letko E, Papaliodis DN, Papaliodis GN, Daoud YJ, Ahmed AR, Foster CS. Stevens-Johnson syndrome and toxic epidermal necrolysis: a review of the literature. Ann Allergy Asthma Immunol. 2005 Apr;94(4):419-36; quiz 436-8, 456. Review.

12451.     Luskin AT. What the asthma end points we know and love do and do not tell us. J Allergy Clin Immunol. 2005 Apr;115(4 Suppl):S539-45. Review.

12452.     Malmberg LP, Turpeinen H, Rytila P, Sarna S, Haahtela T. Determinants of increased exhaled nitric oxide in patients with suspected asthma. Allergy. 2005 Apr;60(4):464-8.

12453.     Mansur AT, Aydingoz IA. A case of toxic epidermal necrolysis with lesions mostly on sun-exposed skin. Photodermatol Photoimmunol Photomed. 2005 Apr;21(2):100-2. 

12454.     Matsumoto K, Shimanouchi Y, Kawakubo K, Oishi N, Wakiguchi H, Futamura K, Saito H.  Infantile eczema at one month of age is associated with cord blood eosinophilia and subsequent development of atopic dermatitis and wheezing illness until two years of age. Int Arch Allergy Immunol. 2005;137 Suppl 1:69-76.

12455.     Nel A. Atmosphere. Air pollution-related illness: effects of particles. Science. 2005 May 6;308(5723):804-6.

12456.     Nicholson PJ, Cullinan P, Taylor AJ, Burge PS, Boyle C.  Evidence based guidelines for the prevention, identification, and management of occupational asthma. Occup Environ Med. 2005 May;62(5):290-9. Review. 

12457.     Nunnelee JD. Summer injuries. Bites & stings. RN. 2005 Apr;68(4):56-8, 60-1; quiz 62. Review.

12458.     Palomares O, Cuesta-Herranz J, Rodriguez R, Villalba M. A recombinant precursor of the mustard allergen Sin a 1 retains the biochemical and immunological features of the heterodimeric native protein. Int Arch Allergy Immunol. 2005 May;137(1):18-26.

12459.     Radcliffe M, Scadding G, Brown HM. Lupin flour anaphylaxis. Lancet. 2005 Apr 9-15;365(9467):1360.

12460.     Ritz BW, Lord RS. Case study: The effectiveness of a dietary supplement regimen in reducing IgG-mediated food sensitivity in ADHD. Altern Ther Health Med. 2005 May-Jun;11(3):72-5.

12461.     Sabina AB, Williams AL, Wall HK, Bansal S, Chupp G, Katz DL. Yoga intervention for adults with mild-to-moderate asthma: a pilot study. Ann Allergy Asthma Immunol. 2005 May;94(5):543-8.

12462.     Saeed SA. Hyposensitization. J Coll Physicians Surg Pak. 2005 Apr;15(4):250.

12463.     Sahin MT, Ozturkcan S, Inanir I, Filiz EE. Norfloxacin-induced toxic epidermal necrolysis. Ann Pharmacother. 2005 Apr;39(4):768-70.

12464.     Shirai T, Matsui T, Suzuki K, Chida K. Effect of pet removal on pet allergic asthma. Chest. 2005 May;127(5):1565-71.

12465.     Shivbalan S, Balasubramanian S, Anandnathan K. What do parents of asthmatic children know about asthma?: An Indian perspective. Indian J Chest Dis Allied Sci. 2005 Apr-Jun;47(2):81-7. 

12466.     Song TT, Nelson MR, Chang JH, Engler RJ, Chowdhury BA. Adequacy of the epinephrine autoinjector needle length in delivering epinephrine to the intramuscular tissues. Ann Allergy Asthma Immunol. 2005 May;94(5):539-42.

12467.     Sood A. Does obesity weigh heavily on the health of the human airway? J Allergy Clin Immunol. 2005 May;115(5):921-4.

12468.     Szefler SJ. Airway remodeling: therapeutic target or not? Am J Respir Crit Care Med. 2005 Apr 1;171(7):672-3.

12469.     Szefler SJ. Facing the challenges of childhood asthma: what changes are necessary? J Allergy Clin Immunol. 2005 Apr;115(4):685-8. Review.

12470.     Tamura G, Suda Y. Images in clinical medicine. Airway dilatation after inhalation of a beta-agonist. N Engl J Med. 2005 Apr 14;352(15):e14.

12471.     Tuchinda C, Leenutaphong V, Sudtim S, Lim HW. Fixed solar urticaria induced by UVA and visible light: a report of a case. Photodermatol Photoimmunol Photomed. 2005 Apr;21(2):97-9. Review.

12472.     Varadarajulu S. Urticaria and angioedema. Controlling acute episodes, coping with chronic cases. Postgrad Med. 2005 May;117(5):25-31. Review.

12473.     Viljanen M, Savilahti E, Haahtela T, Juntunen-Backman K, Korpela R, Poussa T, Tuure T, Kuitunen M. Probiotics in the treatment of atopic eczema/dermatitis syndrome in infants: a double-blind placebo-controlled trial. Allergy. 2005 Apr;60(4):494-500.

12474.     Wang J, Sicherer SH. Anaphylaxis following ingestion of candy fruit chews. Ann Allergy Asthma Immunol. 2005 May;94(5):530-3.

12475.     Welt K, Hinrichs R, Ott S, Thalmann M, Dieckmannken J, Schneider LA, Staib G, Scharffetter-Kochanek K. Anaphylaxis after the ingestion of lamb meat. Allergy. 2005 Apr;60(4):545.

12476.     Wilson C. Recurrent vulvovaginitis candidiasis; an overview of traditional and alternative therapies. Adv Nurse Pract. 2005 May;13(5):24-9; quiz 30. Review.

12477.     Yawalkar N. Drug-induced exanthems. Toxicology. 2005 Apr 15;209(2):131-4. Review.

Pathogenesis

12478.     Aster RH. Drug-induced immune cytopenias. Toxicology. 2005 Apr 15;209(2):149-53. 

12479.     Berger RE. Fixed drug eruption--a sexually inducible reaction? J Urol. 2005 Jun;173(6):1990.

12480.     Carraro S, Corradi M, Zanconato S, Alinovi R, Pasquale MF, Zacchello F, Baraldi E.  Exhaled breath condensate cysteinyl leukotrienes are increased in children with exercise-induced bronchoconstriction. J Allergy Clin Immunol. 2005 Apr;115(4):764-70.

12481.     Cavani A.  Breaking tolerance to nickel. Toxicology. 2005 Apr 15;209(2):119-21. Review.

12482.     Christiansen C.  X-ray contrast media--an overview. Toxicology. 2005 Apr 15;209(2):185-7. Review.

12483.     Cloutier MM, Hall CB, Wakefield DB, Bailit H. Use of asthma guidelines by primary care providers to reduce hospitalizations and emergency department visits in poor, minority, urban children. J Pediatr. 2005 May;146(5):591-7. 

12484.     Currie GP, Lee DK. Beneficial antiinflammatory effects of leukotriene receptor antagonists in asthma. Chest. 2005 Apr;127(4):1458.

12485.     Falcone FH, Pritchard DI. Parasite role reversal: worms on trial. Trends Parasitol. 2005 Apr;21(4):157-60. Review.

12486.     Fineberg SE, Kawabata T, Finco-Kent D, Liu C, Krasner A. Antibody response to inhaled insulin in patients with type 1 or type 2 diabetes. An analysis of initial phase II and III inhaled insulin (Exubera) trials and a two-year extension trial. J Clin Endocrinol Metab. 2005 Jun;90(6):3287-94.

12487.     Gern JE, Rosenthal LA, Sorkness RL, Lemanske RF Jr. Effects of viral respiratory infections on lung development and childhood asthma. J Allergy Clin Immunol. 2005 Apr;115(4):668-74; quiz 675. Review.

12488.     Greenberger PA.  Epinephrine for anaphylaxis. Ann Allergy Asthma Immunol. 2005 May;94(5):515-6.

12489.     Jain S. Proton-pump inhibitor therapy for gastroesophageal reflux disease: does it treat the asthma? Chest. 2005 Apr;127(4):1097-8.

12490.     Kim LS, Riedlinger JE, Baldwin CM, Hilli L, Khalsa SV, Messer SA, Waters RF.  Treatment of seasonal allergic rhinitis using homeopathic preparation of common allergens in the southwest region of the US: a randomized, controlled clinical trial. Ann Pharmacother. 2005 Apr;39(4):617-24.

12491.     Konno S, Golden DB, Schroeder J, Hamilton RG, Lichtenstein LM, Huang SK.  Increased expression of osteopontin is associated with long-term bee venom immunotherapy. J Allergy Clin Immunol. 2005 May;115(5):1063-7.

12492.     Kuehn BM. Therapy takes wheeze out of cat allergies. JAMA. 2005 May 11;293(18):2201.

12493.     Li YF, Langholz B, Salam MT, Gilliland FD. Maternal and grandmaternal smoking patterns are associated with early childhood asthma. Chest. 2005 Apr;127(4):1232-41.

12494.     Linhart B, Hartl A, Jahn-Schmid B, Verdino P, Keller W, Krauth MT, Valent P, Horak F, Wiedermann U, Thalhamer J, Ebner C, Kraft D, Valenta R. A hybrid molecule resembling the epitope spectrum of grass pollen for allergy vaccination. J Allergy Clin Immunol. 2005 May;115(5):1010-6.

12495.     Linneberg A. Hypothesis: urbanization and the allergy epidemic--a reverse case of immunotherapy? Allergy. 2005 Apr;60(4):538-9.

12496.     Liu XS, Xu YJ. Potassium channels in airway smooth muscle and airway hyperreactivity in asthma. Chin Med J (Engl). 2005 Apr 5;118(7):574-80. Review.

12497.     McBrien ME, Webb ST, Breslin. Anaphylaxis and anaesthesia. Br J Anaesth. 2005 Apr;94(4):547-8; author reply 548.

12498.     McKeever TM, Lewis SA, Smit HA, Burney P, Britton JR, Cassano PA.  The association of acetaminophen, aspirin, and ibuprofen with respiratory disease and lung function. Am J Respir Crit Care Med. 2005 May 1;171(9):966-71.

12499.     Mertes PM. Anaphylactic reactions during anaesthesia--let us treat the problem rather than debating its existence. Acta Anaesthesiol Scand. 2005 Apr;49(4):431-3.

12500.     Murch S. Diet, immunity, and autistic spectrum disorders. J Pediatr. 2005 May;146(5):582-4. Review.

12501.     Peacock ME, Park DS, Swiec GD, Erley KJ. Perioral angioedema associated with angiotensin-converting enzyme inhibitor. J Periodontol. 2005 Apr;76(4):651-4.

12502.     Prescott RA, Potter PC. Hypersensitivity to airborne spitting cobra snake venom. Ann Allergy Asthma Immunol. 2005 May;94(5):600-3.

12503.     Rahman M, Haider N. Anticonvulsant hypersensitivity syndrome from addition of lamotrigine to divalproex. Am J Psychiatry. 2005 May;162(5):1021.

12504.     Romano A, Gueant-Rodriguez RM, Viola M, Gaeta F, Caruso C, Gueant JL. Cross-reactivity among drugs: clinical problems. Toxicology. 2005 Apr 15;209(2):169-79. Review.

12505.     Shi HZ. DNA vaccine and asthma therapy. Chin Med J (Engl). 2005 Apr 5;118(7):531-3.

12506.     Szeplaki G, Varga L, Valentin S, Kleiber M, Karadi I, Romics L, Fust G, Farkas H.   Adverse effects of danazol prophylaxis on the lipid profiles of patients with hereditary angioedema. J Allergy Clin Immunol. 2005 Apr;115(4):864-9.

12507.     Thomas M, Crawford I. Best evidence topic report. Glucagon infusion in refractory anaphylactic shock in patients on beta-blockers. Emerg Med J. 2005 Apr;22(4):272-3. Review.

12508.     Williams HC. Clinical practice. Atopic dermatitis. N Engl J Med. 2005 Jun 2;352(22):2314-24. Review.

Vaccines:

12509.   Plotkin SA. Vaccines: past, present and future. Nat Med. 2005 Apr;11(4 Suppl):S5-11

Therapy:

12510.     Cace N, Brusich S, Dessardo S, Ahel J. Cardiopulmonary bypass in a child with hereditary angioedema. Pediatr Int. 2005 Apr;47(2):214-6.

12511.     Check E. Gene therapists urged to learn more immunology. Nature. 2005 Apr 14;434(7035):812.

12512.     Green R, Ball A. Alpha-agonists for the treatment of anaphylactic shock. Anaesthesia. 2005 Jun;60(6):621-2.

12513.     Kemp SF. Got epinephrine? Many patients with anaphylaxis reportedly stuck with no epinephrine syringes. Ann Allergy Asthma Immunol. 2005 May;94(5):513-4.

12514.     Mennick F. Treating asthma in pregnancy: what's good for women is good for fetuses, too. Am J Nurs. 2005 Apr;105(4):20.

12515.     Muething SE, Kotagal U. Reliability of the health care delivery system. J Pediatr. 2005 May;146(5):581-2.

12516.     Walters JA, Wood-Baker R, Walters EH. Long-acting beta2-agonists in asthma: an overview of Cochrane systematic reviews. Respir Med. 2005 Apr;99(4):384-95. Review.

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