leishmaniasis

Selected abstracts:

1.                  Piscopo TV, Mallia Azzopardi C. Leishmaniasis. Postgrad Med J. 2007 Feb;83(976):649-57.
St Luke's Hospital, Guardamangia Hill, Guardamangia, MSD 09, Malta. tonio.piscopo@gov.mt
Epidemiology, disease patterns, immunology, diagnosis, treatment and control measures of leishmaniasis are described. Various issues relating to leishmaniasis are highlighted: the relative lack of importance given to this disease compared with other infections, climate change and its possible impact on extension of endemicity of this infection, and new diagnostic tests which are improving diagnosis, especially in resource poor areas. Other important aspects discussed include the potential for newer oral therapy to change the way this disease is managed; Leishmania-HIV coinfection and groups at risk; and development of an effective vaccine.

15856.  Konecny P, Stark DJ.  An Australian case of New World cutaneous leishmaniasis. Med J Aust. 2007 Mar 19;186(6):315-7.

15857.  Lezama-Davila CM, Oghumu S, Satoskar AR, Isaac-Marquez AP. Sex-associated susceptibility in humans with chiclero's ulcer: resistance in females is associated with increased serum-levels of GM-CSF. Scand J Immunol. 2007 Feb;65(2):210-1.

15858.  Niamba P, Goumbri-Lompo O, Traore A, Barro-Traore F, Soudre RT.  Diffuse cutaneous leishmaniasis in an HIV-positive patient in western Africa. Australas J Dermatol. 2007 Feb;48(1):32-4. 

15859.  Reithinger R, Dujardin JC.  Molecular diagnosis of leishmaniasis: current status and future applications. J Clin Microbiol. 2007 Jan;45(1):21-5.

15860.  Sakru N, Korkmaz M, Ozbel Y, Ertabaklar H, Sengul M, Toz SO. Investigation of asymptomatic visceral leishmaniasis cases using western blot in an endemic area in Turkey. New Microbiol. 2007 Jan;30(1):13-8. 

15861.  Solomon M, Baum S, Barzilai A, Scope A, Trau H, Schwartz E.  Liposomal amphotericin B in comparison to sodium stibogluconate for cutaneous infection due to Leishmania braziliensis. J Am Acad Dermatol. 2007 Apr;56(4):612-6.

15862.  Sundar S, Singh RK, Bimal SK, Gidwani K, Mishra A, Maurya R, Singh SK, Manandhar KD, Boelaert M, Rai M.  Comparative evaluation of parasitology and serological tests in the diagnosis of visceral leishmaniasis in India: a phase III diagnostic accuracy study. Trop Med Int Health. 2007 Feb;12(2):284-9. 

Pathogenesis:

15863.  Kuru T, Jirata D,  Genetu A,  Barr S,  Mengistu Y,  Aseffa A,  Gedamu L. Leishmania aethiopica: identification and characterization of cathepsin L-like cysteine protease genes. Exp Parasitol. 2007 Mar;115(3):283-90.

Chemotherapy, Immunotherapy, Management & Drugs:

15864.  Machado PR, Lessa H,  Lessa M,  Guimaraes LH,  Bang H,  Ho JL,  Carvalho EM. Oral pentoxifylline combined with pentavalent antimony: a randomized trial for mucosal leishmaniasis. Clin Infect Dis. 2007 Mar 15;44(6):788-93.