Selected abstracts:

1.                  Bax JJ, Bonow RO, Tschope D, Inzucchi SE, Barrett E; Global Dialogue Group for the Evaluation of Cardiovascular Risk in Patients With Diabetes. The potential of myocardial perfusion scintigraphy for risk stratification of asymptomatic patients with type 2 diabetes. J Am Coll Cardiol. 2006 Aug 15;48(4):754-60.

           Leiden University Medical Center, Leiden, The Netherlands.

                  Patients with diabetes, in particular patients with type 2 diabetes, are at a 2- to 4-fold higher risk of cardiovascular mortality compared with their nondiabetic peers. Patients with diabetes are also more likely to have silent ischemia and less likely to survive a myocardial infarction than nondiabetic patients. Recent studies with electron beam computed tomography (EBCT) have shown that subclinical atherosclerosis is common in patients with diabetes, and studies with myocardial perfusion scintigraphy (with single-photon emission computed tomography) or stress echocardiography have demonstrated that between 25% and 50% of asymptomatic diabetic patients have ischemia during exercise or pharmacological stress and that a substantial proportion of these patients go on to develop major cardiovascular events within several years. Clearly, asymptomatic diabetic patients include a subset of individuals at high risk of cardiovascular disease who would benefit from improved risk stratification beyond that possible with risk factor scoring systems alone. Single-photon emission computed tomography, stress echocardiography, and possibly EBCT or multi-slice computed tomography, are emerging as valuable diagnostic tools for identifying asymptomatic diabetic patients who might require early and aggressive intervention to manage their cardiovascular risk.

1.                  Breslau N. Neurobiological research on sleep and stress hormones in epidemiological samples. Ann N Y Acad Sci. 2006 Jul;1071:221-30. Review. 

Department of Epidemiology, Michigan State University, B645 West Fee Hall, East Lansing, MI 48824, USA.

Information on stress hormones and sleep disturbance in posttraumatic stress disorder (PTSD) is on the basis of clinical samples and samples of other selective populations. Neurobiological studies nested in a large epidemiological community sample were recently reported. PTSD was compared with several control groups, defined by exposure and by diagnostic classification on the basis of comorbidity with Major Depression. Key findings were: (a) higher mean catecholamines in persons with PTSD versus controls; (b) no difference in mean cortisol between groups; (c) comorbid PTSD and depression was associated with higher cortisol in women; and (d) polysomnographic studies failed to detect clinically relevant sleep disturbance in PTSD, although an increase in brief arousal from REM was detected. Methodological questions raised by discrepancies between biological findings from epidemiologic versus clinical and other selective samples are discussed.

2.                  Haidara MA, Yassin HZ, Rateb M, Ammar H, Zorkani MA. Role of oxidative stress in development of cardiovascular complications in diabetes mellitus. Curr Vasc Pharmacol. 2006 Jul;4(3):215-27. Review.

Department of Physiology, Kasr Al-Aini Faculty of Medicine, Cairo University, Egypt.

Diabetes represents a serious risk factor for the development of cardiovascular problems such as coronary heart disease, peripheral arterial disease, hypertension, stroke, cardiomyopathy, nephropathy and retinopathy. Identifying the pathogenesis of this increased risk provides a basis for secondary intervention to reduce morbidity and mortality in diabetic patients. Hyperglycemia and protein glycation, increased inflammation, a prothrombotic state and endothelial dysfunction have all been implicated as possible mechanisms for such complications. A linking element between many of these phenomena could possibly be, among other factors, increased production of reactive oxygen species. Vascular endothelial cells have several physiological actions that are essential for the normal function of the cardiovascular system. These include the production of nitric oxide (NO), which regulates vasodilatation, anticoagulation, leukocyte adhesion, smooth muscle proliferation and the antioxidative capacity of endothelial cells. However, under conditions of hyperglycemia, excessive amounts of superoxide radicals are produced inside vascular cells and this can interfere with NO production leading to the possible complications. This article aims at reviewing the links between reactive oxygen species, diabetes and vascular disease and whether or not antioxidants can alter the course of vascular complications in diabetic patients and animal models. A possible beneficial effect of antioxidants might present a new addition to the range of secondary preventive measures used in diabetic patients.

4.                  Harmsen P, Lappas G, Rosengren A, Wilhelmsen L.  Long-term risk factors for stroke: twenty-eight years of follow-up of 7457 middle-aged men in Goteborg, Sweden. Stroke. 2006 Jul;37(7):1663-7 .

Institute of Clinical Neuroscience, Sahlgrenska University Hospital, Goteborg, Sweden.

BACKGROUND AND PURPOSE: To estimate the predictive value of risk factors for stroke measured in midlife over follow-up extending through 28 years. METHODS: A cohort of 7457 men 47 to 55 years of age and free of stroke at baseline year 1970 were examined. Risk of stroke was analyzed for the entire period and for 0 to 15, 16 to 21, and 22 to 28 years of follow-up using age-adjusted and multiple Cox regression analyses. RESULTS: Age, diabetes, and high blood pressure were independently associated with increased risk of stroke for the entire 28 years and for each of the periods. Previous transient ischemic attacks, atrial fibrillation, history of chest pain, smoking, and psychological stress were independently related to stroke for the entire follow-up period and also during the first 1 or 2 successive periods. Family history of stroke or of coronary disease carried no independent prognostic information, nor did serum cholesterol. Elevated body mass index predicted stroke during the later part of the follow-up and so did (almost) low physical activity during leisure time, together with antihypertensive medication at baseline. CONCLUSIONS: High blood pressure and diabetes retain their importance as stroke risk factors also over an extended follow-up into old age. A family history of cardiovascular disease was not significantly related to outcome. Transient ischemic attacks, atrial fibrillation, stress, smoking, and a history of chest pain were associated with outcome only for the first or the first 2 periods. High body mass index and antihypertensive medication at baseline emerged as risk factors in the second and third decades.

5.                  Levinson DF. The genetics of depression: a review. Biol Psychiatry. 2006 Jul 15;60(2):84-92.

Department of Psychiatry, Center for Neurobiology and Behavior, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania 19104-3309, USA.

Major depressive disorder (MDD) is common and moderately heritable. Recurrence and early age at onset characterize cases with the greatest familial risk. Major depressive disorder and the neuroticism personality trait have overlapping genetic susceptibilities. Most genetic studies of MDD have considered a small set of functional polymorphisms relevant to monoaminergic neurotransmission. Meta-analyses suggest small positive associations between the polymorphism in the serotonin transporter promoter region (5-HTTLPR) and bipolar disorder, suicidal behavior, and depression-related personality traits but not yet to MDD itself. This polymorphism might also influence traits related to stress vulnerability. Newer hypotheses of depression neurobiology suggest closer study of genes related to neurotoxic and neuroprotective (neurotrophic) processes and to overactivation of the hypothalamic-pituitary axis, with mixed evidence regarding association of MDD with polymorphisms in one such gene (brain-derived neurotrophic factor [BDNF]). Several genome-wide linkage studies of MDD and related traits have been reported or are near completion. There is some evidence for convergence of linkage findings across studies, but more data are needed to permit meta-analysis. Future directions will include more intensive, systematic study of linkage candidate regions and of the whole genome for genetic association; gene expression array studies; and larger-scale studies of gene-environment interactions and of depression-related endophenotypes.


6.                  Olson AL, Dietrich AJ, Prazar G, Hurley J.  Brief maternal depression screening at well-child visits. Pediatrics. 2006 Jul;118(1):207-16.

Department of Pediatrics, Dartmouth Hitchcock Medical Center, HB                                                                   7450, 1 Medical Center Dr, Lebanon, New Hampshire 03756-0011, USA

OBJECTIVES: The goals were (1) to determine the feasibility and yield of maternal depression screening during all well-child visits, (2) to understand how pediatricians and mothers respond to depression screening information, and (3) to assess the time required for discussion of screening results. METHODS: Implementation of brief depression screening of mothers at well-child visits for children of all ages was studied in 3 rural pediatric practices. Two screening trials introduced screening (1 month) and then determined whether screening could be sustained (6 months). Screening used the 2-question Patient Health Questionnaire. Practices tracked the proportions of visits screened and provided data about the screening process. RESULTS: Practices were able to screen in the majority of well-child visits (74% in trial 1 and 67% in trial 2). Of 1398 mothers screened, 17% had 1 of the depressive symptoms and 6% (n = 88) scored as being at risk for a major depressive disorder. During discussion, 5.7% of all mothers thought they might be depressed and 4.7% thought they were stressed but not depressed. Pediatric clinicians intervened with 62.4% of mothers who screened positive and 38.2% of mothers with lesser symptoms. Pediatrician actions included discussion of the impact on the child, a follow-up visit or call, and referral to an adult primary care provider, a mental health clinician, or community supports. Pediatrician time needed to discuss screening results decreased in the second trial. Prolonged discussion time was uncommon (5-10 minutes in 3% of all well-child visits and >10 minutes in 2%). CONCLUSIONS: Routine, brief, maternal depression screening conducted during well-child visits was feasible and detected mothers who were willing to discuss depression and stress issues with their pediatrician. The discussion after screening revealed additional mothers who felt depressed among those with lesser symptoms. The additional discussion time was usually brief and resulted in specific pediatrician actions.

7.                  Ross LE, McLean LM.  Anxiety disorders during pregnancy and the postpartum period: A systematic review. J Clin Psychiatry. 2006 Aug;67(8):1285-98. Review.  

Women's Mental Health and Addiction Research Section, Centre for Addiction and Mental Health, Department of Psychiatry, University of Toronto, Toronto, Ontario, Canada.

OBJECTIVE: The postpartum period is recognized as a time of vulnerability to affective disorders, particularly postpartum depression. In contrast, the prevalence and clinical presentation of anxiety disorders during pregnancy and the postpartum period have received little research attention. In this article, we review the medical literature as it relates to the prevalence and clinical presentation of panic disorder, obsessive-compulsive disorder, posttraumatic stress disorder, and generalized anxiety disorder during pregnancy and the postpartum period. DATA SOURCES: MEDLINE (1966 to July 2005 week 1) and PsycInfo (1840 to July 2005 week 1) were searched using combinations of the following search terms: pregnancy, childbirth, postpartum, panic disorder, phobia, obsessive-compulsive disorder, posttraumatic stress disorder, and generalized anxiety disorder. STUDY SELECTION: All relevant papers published in English and reporting original data related to perinatal anxiety disorders were included. DATA EXTRACTION: Studies were examined for data related to the prevalence, presentation, predictors/risk factors, new onset, course, and treatment of anxiety disorders during pregnancy and the postpartum period. DATA SYNTHESIS: Anxiety disorders are common during the perinatal period, with reported rates of obsessive-compulsive disorder and generalized anxiety disorder being higher in postpartum women than in the general population. The perinatal context of anxiety disorders presents unique issues for detection and management. CONCLUSIONS: Future research is needed to estimate the prevalence of perinatal anxiety disorders more precisely, to identify potential implications of maternal anxiety disorders for maternal quality of life and child development, and to determine safe and effective treatment methods.

8.                  Simon NM, Smoller JW, McNamara KL, Maser RS, Zalta AK, Pollack MH, Nierenberg AA, Fava M, Wong KK. Telomere shortening and mood disorders: preliminary support for a chronic stress model of accelerated aging. Biol Psychiatry. 2006 Sep 1;60(5):432-5.

Department of Psychiatry, Massachusetts General Hospital and Harvard Medical School, Boston, MA 02114, USA.      

BACKGROUND: Little is known about the biological mechanisms underlying the excess medical morbidity and mortality associated with mood disorders. Substantial evidence supports abnormalities in stress-related biological systems in depression. Accelerated telomere shortening may reflect stress-related oxidative damage to cells and accelerated aging, and severe psychosocial stress has been linked to telomere shortening. We propose that chronic stress associated with mood disorders may contribute to excess vulnerability for diseases of aging such as cardiovascular disease and possibly some cancers through accelerated organismal aging. METHODS: Telomere length was measured by Southern Analysis in 44 individuals with chronic mood disorders and 44 nonpsychiatrically ill age-matched control subjects. RESULTS: Telomere length was significantly shorter in those with mood disorders, representing as much as 10 years of accelerated aging. CONCLUSIONS: These results provide preliminary evidence that mood disorders are associated with accelerated aging and may suggest a novel mechanism for mood disorder-associated morbidity and mortality.


9.                  Thompson JB, Rivera JJ, Blumenthal RS, Danyi P. Primary prevention for patients with intermediate Framingham risk scores. Curr Cardiol Rep. 2006 Jul;8(4):261-6. Review.

Coronary heart disease (CHD) is the leading cause of mortality in the industrialized world. Proper identification of individuals at risk for CHD is challenging. The Framingham Risk Score, the most widely accepted tool for quantifying 10-year risk, fails to identify a great proportion of future CHD. Because of the health and economic consequences of CHD, there is a need to develop better prognostic tools for primary prevention. Coronary artery calcium scoring, C-reactive protein measurement, and heart rate recovery and exercise tolerance during exercise stress test may be useful tools for better risk stratification of intermediate-risk patients.


10.              Wolber T, Maeder M, Weilenmann D, Duru F, Bluzaite I, Riesen W, Rickli H, Ammann P.  Integration of B-type natriuretic peptide levels with clinical data and exercise testing for predicting coronary artery disease. Am J Cardiol. 2006 Sep 15;98(6):764-7

Cardiovascular Center, Cardiology, University Hospital Zurich, Zurich, Switzerland.

Natriuretic peptides have been shown to be high in patients with myocardial ischemia. We sought to create a diagnostic score using clinical data, stress testing, and B-type natriuretic peptide (BNP) levels to improve noninvasive prediction of coronary artery disease (CAD). Patients with stable angina pectoris and normal systolic left ventricular function were eligible for this prospective cohort study. Patients with arrhythmias, valvular heart disease, impaired left ventricular function, or renal dysfunction were excluded. All patients underwent clinical evaluation, bicycle stress testing, BNP testing, and coronary angiography. Then a diagnostic risk score was derived that combined cardiovascular risk factors, results of exercise testing, and BNP measurements and added 1 point for the presence of each of these variables. Seventy-one patients (52 years of age, range 31 to 61; 46 men) were included in the study. Prevalence of CAD, defined by 50% narrowing of > or =1 coronary artery on coronary angiography, was 45%. For 0 point in the risk score system, the negative predictive value was 93% with a negative likelihood ratio of 0.1 (95% confidence interval [CI] 0.02 to 0.38); for a score of 3 points, the positive predictive value was 93% with a positive likelihood ratio of 15.9 (95% CI 2.19 to 114.7). Serum BNP level >50 ng/L at rest was the best single diagnostic parameter, with 66% sensitivity and 97% specificity, and a positive likelihood ratio of 25.6 (95% CI 3.64 to 180) and a negative likelihood ratio of 0.35 (95% CI 0.22 to 0.57). In conclusion, a diagnostic score combining exercise testing, clinical data, and serum BNP values at rest can distinguish patients with CAD from those without CAD with high accuracy.


15141.  Ippoliti F, De Santis W, Volterrani A, Canitano N, Frattolillo D, Lucarelli S, Frediani S, Frediani T. Psychological stress affects response to sublingual immunotherapy in asthmatic children allergic to house dust mite. Pediatr Allergy Immunol. 2006 Aug;17(5):337-45. 

15142.  Pohlman B, Becker G. "Stress knocks hard on your immune system": asthma and the discourse on stress. Med Anthropol. 2006 Jul-Sep;25(3):265-95. 

15143.  Saposnik G, Baibergenova A, Dang J, Hachinski V. Does a birthday predispose to vascular events? Neurology. 2006 Jul 25;67(2):300-4.

15144.  Shimizu Y, Dobashi K, Kobayashi S, Ohki I, Tokushima M, Kusano M, Kawamura O, Shimoyama Y, Utsugi M, Sunaga N, Ishizuka T, Mori M. A proton pump inhibitor, lansoprazole, ameliorates asthma symptoms in asthmatic patients with gastroesophageal reflux disease. Tohoku J Exp Med. 2006 Jul;209(3):181-9. 


15145.  Amirkhanyan AA, Wolf DA. Parent care and the stress process: findings from panel data. J Gerontol B Psychol Sci Soc Sci. 2006 Sep;61(5):S248-55. 

15146.  Ando T, Hashiro M, Noda K, Adachi J, Hosoya R, Kamide R, Ishikawa T, Komaki G.  Development and validation of the psychosomatic scale for atopic dermatitis in adults. J Dermatol. 2006 Jul;33(7):439-50.

15147.  Angermeyer MC, Bull N, Bernert S, Dietrich S, Kopf A. Burnout of caregivers: a comparison between partners of psychiatric patients and nurses. Arch Psychiatr Nurs. 2006 Aug;20(4):158-65. 

15148.  Arving C, Sjoden PO, Bergh J, Lindstrom AT, Wasteson E, Glimelius B, Brandberg Y. Satisfaction, utilisation and perceived benefit of individual psychosocial support for breast cancer patients--a randomised study of nurse versus psychologist interventions. Patient Educ Couns. 2006 Aug;62(2):235-43.     

15149.  Brown ES, Beard L, Frol AB, Rush AJ. Effect of two prednisone exposures on mood and declarative memory. Neurobiol Learn Mem. 2006 Jul;86(1):28-34.

15150.  Campagne DM. Should fertilization treatment start with reducing stress? Hum Reprod. 2006 Jul;21(7):1651-8.

15151.  Dyl J, Kittler J, Phillips KA, Hunt JI. Body dysmorphic disorder and other clinically significant body image concerns in adolescent psychiatric inpatients: prevalence and clinical characteristics. Child Psychiatry Hum Dev. 2006 Summer;36(4):369-82. 

15152.  Evans-Campbell T, Lindhorst T, Huang B, Walters KL. Interpersonal violence in the lives of urban American Indian and Alaska Native women: implications for health, mental health, and help-seeking. Am J Public Health. 2006 Aug;96(8):1416-22.

15153.  Fulkerson JA, Story M, Mellin A, Leffert N, Neumark-Sztainer D, French SA.   Family dinner meal frequency and adolescent development: relationships with developmental assets and high-risk behaviors. J Adolesc Health. 2006 Sep;39(3):337-45.

15154.  Gibson EL. Emotional influences on food choice: sensory, physiological and psychological pathways. Physiol Behav. 2006 Aug 30;89(1):53-61.

15155.  Goubert L, Eccleston C, Vervoort T, Jordan A, Crombez G. Parental catastrophizing about their child's pain. The parent version of the Pain Catastrophizing Scale (PCS-P): a preliminary validation. Pain. 2006 Aug;123(3):254-63.

15156.  Hauger RL, Risbrough V, Brauns O, Dautzenberg FM. Corticotropin releasing factor (CRF) receptor signaling in the central nervous system: new molecular targets. CNS Neurol Disord Drug Targets. 2006 Aug;5(4):453-79. Review. 

15157.  Herringa RJ, Roseboom PH, Kalin NH. Decreased amygdala CRF-binding protein mRNA in post-mortem tissue from male but not female bipolar and schizophrenic subjects. Neuropsychopharmacology. 2006 Aug;31(8):1822-31.

15158.  Houry D, Kemball R, Rhodes KV, Kaslow NJ. Intimate partner violence and mental health symptoms in African American female ED patients. Am J Emerg Med. 2006 Jul;24(4):444-50. 

15159.  Inslicht SS, Marmar CR, Neylan TC, Metzler TJ, Hart SL, Otte C, McCaslin SE, Larkin GL, Hyman KB, Baum A. Increased cortisol in women with intimate partner violence-related posttraumatic stress disorder. Psychoneuroendocrinology. 2006 Aug;31(7):825-38.

15160.  Jelinek L, Jacobsen D, Kellner M, Larbig F, Biesold KH, Barre K, Moritz S.   Verbal and nonverbal memory functioning in posttraumatic stress disorder (PTSD). J Clin Exp Neuropsychol. 2006 Aug;28(6):940-8. 

15161.  Johannsen A, Rylander G, Soder B, Asberg M. Dental plaque, gingival inflammation, and elevated levels of interleukin-6 and cortisol in gingival crevicular fluid from women with stress-related depression and exhaustion. J Periodontol. 2006 Aug;77(8):1403-9. 

15162.  Kinzie JD, Cheng K, Tsai J, Riley C. Traumatized refugee children: the case for individualized diagnosis and treatment. J Nerv Ment Dis. 2006 Jul;194(7):534-7. 

15163.  Kissane DW, McKenzie M, Bloch S, Moskowitz C, McKenzie DP, O'Neill I.  Family focused grief therapy: a randomized, controlled trial in palliative care and bereavement. Am J Psychiatry. 2006 Jul;163(7):1208-18. 

15164.  Kitamura T, Hasui C.  Anger feelings and anger expression as a mediator of the effects of witnessing family violence on anxiety and depression in Japanese adolescents. J Interpers Violence. 2006 Jul;21(7):843-55. 

15165.  Lathers CM, Schraeder PL. Stress and sudden death. Epilepsy Behav. 2006 Sep;9(2):236-42.

15166.  Marcellini F, Giuli C, Papa R, Malavolta M, Mocchegiani E. Psychosocial aspects and zinc status: is there a relationship with successful aging? Rejuvenation Res. 2006 Summer;9(2):333-7. 

15167.  Mazzaferro KE, Murray PJ, Ness RB, Bass DC, Tyus N, Cook RL.  Depression, stress, and social support as predictors of high-risk sexual behaviors and STIs in young women. J Adolesc Health. 2006 Oct;39(4):601-3. 

15168.  McCallum TJ, Sorocco KH, Fritsch T.  Mental health and diurnal salivary cortisol patterns among African American and European American female dementia family caregivers. Am J Geriatr Psychiatry. 2006 Aug;14(8):684-93. 

15169.  Miles R, Cowan F, Glover V, Stevenson J, Modi N. A controlled trial of skin-to-skin contact in extremely preterm infants. Early Hum Dev. 2006 Jul;82(7):447-55.

15170.  Orr G, Weiser M, Polliack M, Raviv G, Tadmor D, Grunhaus L.  Effectiveness of sildenafil in treating erectile dysfunction in PTSD patients: a double-blind, placebo-controlled crossover study. J Clin Psychopharmacol. 2006 Aug;26(4):426-30.

15171.  Pence BW, Miller WC, Whetten K, Eron JJ, Gaynes BN. Prevalence of DSM-IV-defined mood, anxiety, and substance use disorders in an HIV clinic in the Southeastern United States. J Acquir Immune Defic Syndr. 2006 Jul;42(3):298-306. 

15172.  Recklitis CJ, Lockwood RA, Rothwell MA, Diller LR.  Suicidal ideation and attempts in adult survivors of childhood cancer. J Clin Oncol. 2006 Aug 20;24(24):3852-7. 

15173.  Segal ZV, Kennedy S, Gemar M, Hood K, Pedersen R, Buis T.  Cognitive reactivity to sad mood provocation and the prediction of depressive relapse. Arch Gen Psychiatry. 2006 Jul;63(7):749-55.

15174.  Stewart DW, de Vries J, Singer DL, Degen GG, Wener P. Canadian dental students' perceptions of their learning environment and psychological functioning over time. J Dent Educ. 2006 Sep;70(9):972-81.

15175.  Ter Bogt TF, van Dorsselaer SA, Monshouwer K, Verdurmen JE, Engels RC, Vollebergh WA.  Body mass index and body weight perception as risk factors for internalizing and externalizing problem behavior among adolescents. J Adolesc Health. 2006 Jul;39(1):27-34. 

15176.  Waldinger MD, Schweitzer DH.  Changing paradigms from a historical DSM-III and DSM-IV view toward an evidence-based definition of premature ejaculation. Part I--validity of DSM-IV-TR. J Sex Med. 2006 Jul;3(4):682-92. Review. 

15177.  Whitaker RC, Phillips SM, Orzol SM. Food insecurity and the risks of depression and anxiety in mothers and behavior problems in their preschool-aged children. Pediatrics. 2006 Sep;118(3):e859-68. 


15178.  Ariff B, Zambanini A, Vamadeva S, Barratt D, Xu Y, Sever P, Stanton A, Hughes A, Thom S.  Candesartan- and atenolol-based treatments induce different patterns of carotid artery and left ventricular remodeling in hypertension. Stroke. 2006 Sep;37(9):2381-4.

15179.  Finsterer J, Gelpi E. Mitochondrial disorder aggravated by propranolol. South Med J. 2006 Jul;99(7):768-71. 

15180.  Konukoglu D, Serin O, Turhan MS. Plasma leptin and its relationship with lipid peroxidation and nitric oxide in obese female patients with or without hypertension. Arch Med Res. 2006 Jul;37(5):602-6.

15181.  Moreno MU, Jose GS, Fortuno A, Beloqui O, Diez J, Zalba G. The C242T CYBA polymorphism of NADPH oxidase is associated with essential hypertension. J Hypertens. 2006 Jul;24(7):1299-306. 

15182.  Palatini P, Longo D, Zaetta V, Perkovic D, Garbelotto R, Pessina AC.  Evolution of blood pressure and cholesterol in stage 1 hypertension: role of autonomic nervous system activity. J Hypertens. 2006 Jul;24(7):1375-81. 

15183.  Sukhija R, Kakar P, Mehta V, Mehta JL. Enhanced 11beta-hydroxysteroid dehydrogenase activity, the metabolic syndrome, and systemic hypertension. Am J Cardiol. 2006 Aug 15;98(4):544-8.

15184.  Taddei S, Versari D, Cipriano A, Ghiadoni L, Galetta F, Franzoni F, Magagna A, Virdis A, Salvetti A. Identification of a cytochrome P450 2C9-derived endothelium-derived hyperpolarizing factor in essential hypertensive patients. J Am Coll Cardiol. 2006 Aug 1;48(3):508-15.

15185.  Thomaides T, Karapanayiotides T, Spantideas A, Andrikou A. Are transient increases in blood pressure during the treadmill stress test associated with headache? Cephalalgia. 2006 Jul;26(7):837-42. 

15186.  Xu S, Touyz RM. Reactive oxygen species and vascular remodelling in hypertension: still alive. Can J Cardiol. 2006 Sep;22(11):947-51. Review. 

15187.  Yang H, Schnall PL, Jauregui M, Su TC, Baker D.  Work hours and self-reported hypertension among working people in California. Hypertension. 2006 Oct;48(4):744-50.

Heart Disease:

15188.  Abe N, Matsunaga T, Kameda K, Tomita H, Fujiwara T, Ishizaka H, Hanada H, Fukui K, Fukuda I, Osanai T, Okumura K. Increased level of pericardial insulin-like growth factor-1 in patients with left ventricular dysfunction and advanced heart failure. J Am Coll Cardiol. 2006 Oct 3;48(7):1387-95.

15189.  Adamopoulos S, Parissis JT, Iliodromitis EK, Paraskevaidis I, Tsiapras D, Farmakis D, Karatzas D, Gheorghiade M, Filippatos GS, Kremastinos DT.   Effects of levosimendan versus dobutamine on inflammatory and apoptotic pathways in acutely decompensated chronic heart failure. Am J Cardiol. 2006 Jul 1;98(1):102-6.

15190.  Bella JN, Palmieri V, Roman MJ, Paranicas MF, Welty TK, Lee ET, Fabsitz RR, Howard BV, Devereux RB. Gender differences in left ventricular systolic function in American Indians (from the Strong Heart Study). Am J Cardiol. 2006 Sep 15;98(6):834-7.

15191.  Corrrigan M, Cupples ME, Smith SM, Byrne M, Leathem CS, Clerkin P, Murphy AW. The contribution of qualitative research in designing a complex intervention for secondary prevention of coronary heart disease in two different healthcare systems. BMC Health Serv Res. 2006 Jul 18;6:90.

15192.  Edelman D, Oddone EZ, Liebowitz RS, Yancy WS Jr, Olsen MK, Jeffreys AS, Moon SD, Harris AC, Smith LL, Quillian-Wolever RE, Gaudet TW. A multidimensional integrative medicine intervention to improve cardiovascular risk. J Gen Intern Med. 2006 Jul;21(7):728-34. 

15193.  Giallauria F, Lucci R, Pietrosante M, Gargiulo G, De Lorenzo A, D'Agostino M, Gerundo G, Abete P, Rengo F, Vigorito C. Exercise-based cardiac rehabilitation improves heart rate recovery in elderly patients after acute myocardial infarction. J Gerontol A Biol Sci Med Sci. 2006 Jul;61(7):713-7. 

15194.  Haidara MA, Yassin HZ, Rateb M, Ammar H, Zorkani MA. of oxidative stress in development of cardiovascular complications in diabetes mellitus. Curr Vasc Pharmacol. 2006 Jul;4(3):215-27. Review. 

15195.  Hankey GJ. Potential new risk factors for ischemic stroke: what is their potential?  Stroke. 2006 Aug;37(8):2181-8. Epub 2006 Jun 29. Review.  

15196.  Koenig W, Twardella D, Brenner H, Rothenbacher D. Lipoprotein-associated phospholipase A2 predicts future cardiovascular events in patients with coronary heart disease independently of traditional risk factors, markers of inflammation, renal function, and hemodynamic stress. Arterioscler Thromb Vasc Biol. 2006 Jul;26(7):1586-93.

15197.  Kurian KC, Rai P, Sankaran S, Jacob B, Chiong J, Miller AB. The effect of statins in heart failure: beyond its cholesterol-lowering effect. J Card Fail. 2006 Aug;12(6):473-8. Review. 

15198.  Pokan R, Hofmann P, von Duvillard SP, Smekal G, Wonisch M, Lettner K, Schmid P, Shechter M, Silver B, Bachl N. Oral magnesium therapy, exercise heart rate, exercise tolerance, and myocardial function in coronary artery disease patients. Br J Sports Med. 2006 Sep;40(9):773-8.

15199.  Rosano GM, Vitale C, Fragasso G. Metabolic therapy for patients with diabetes mellitus and coronary artery disease. Am J Cardiol. 2006 Sep 4;98(5A):14J-18J.

15200.  Shao JS, Cai J, Towler DA. Molecular mechanisms of vascular calcification: lessons learned from the aorta. Arterioscler Thromb Vasc Biol. 2006 Jul;26(7):1423-30.

15201.  Smith DA, Galin I.  Statin therapy for native and peri-interventional coronary heart disease. Curr Mol Med. 2006 Aug;6(5):589-602. Review.

15202.  Suarez JI.  Acute myocardial infarction, ischemic stroke, sympathetic stress, and inflammation: birds of a feather. Stroke. 2006 Oct;37(10):2449-50. Epub 2006 Sep 7.

15203.  Taniai S, Koide Y, Yotsukura M, Nishimura T, Kachi E, Sakata K, Yoshino H.   A new application of the ST-HR loop to evaluate the exercise-induced reversible ischemia in healed anterior wall myocardial infarction. Am J Cardiol. 2006 Aug 1;98(3):346-51.

15204.  Yeh GY, Davis RB, Phillips RS.  Use of complementary therapies in patients with cardiovascular disease. Am J Cardiol. 2006 Sep 1;98(5):673-80. 

Immunological Indicators:

15205.  Calo LA, Dall'Amico R, Pagnin E, Bertipaglia L, Zacchello G, Davis PA.   Oxidative stress and post-transplant hypertension in pediatric kidney-transplanted patients. J Pediatr. 2006 Jul;149(1):53-7.

15206.  Feletou M, Vanhoutte PM.  Endothelial dysfunction: a multifaceted disorder (The Wiggers Award Lecture). Am J Physiol Heart Circ Physiol. 2006 Sep;291(3):H985-1002.

15207.  Konukoglu D, Serin O, Turhan MS.  Plasma leptin and its relationship with lipid peroxidation and nitric oxide in obese female patients with or without hypertension. Arch Med Res. 2006 Jul;37(5):602-6. 

15208.  Leighton F, Miranda-Rottmann S, Urquiaga I. A central role of eNOS in the protective effect of wine against metabolic syndrome. Cell Biochem Funct. 2006 Jul-Aug;24(4):291-8. Review. 

15209.  Moreno MU, Jose GS, Fortuno A, Beloqui O, Diez J, Zalba G. The C242T CYBA polymorphism of NADPH oxidase is associated with essential hypertension. J Hypertens. 2006 Jul;24(7):1299-306. 

15210.  Rogers MS, Wang CC, Tam WH, Li CY, Chu KO, Chu CY.  Oxidative stress in midpregnancy as a predictor of gestational hypertension and pre-eclampsia. BJOG. 2006 Sep;113(9):1053-9. 

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