Diagnosis, Diagnostics, Immunodiagnosis & Immunodiagnostics:

8538.  Bradley VR, Liu V, Haynes HA. Rash with regional lymphadenopathy. Arch Dermatol. 2003 Aug;139(8):1075-80.

8539.  Delobel P, Launois P, Djossou F, Sainte-Marie D, Pradinaud R. American cutaneous leishmaniasis, lepromatous leprosy, and pulmonary tuberculosis coinfection with downregulation of the T-helper 1 cell response. Clin Infect Dis. 2003 Sep 1;37(5):628-33. Epub 2003 Aug 07.

8540.  Faber WR, Oskam L, van Gool T, Kroon NC, Knegt-Junk KJ, Hofwegen H, van der Wal AC, Kager PA. Value of diagnostic techniques for cutaneous leishmaniasis. J Am Acad Dermatol. 2003 Jul;49(1):70-4.

8541.  Marfurt J, Nasereddin A, Niederwieser I, Jaffe CL, Beck HP, Felger I. Identification and differentiation of Leishmania species in clinical samples by PCR amplification of the miniexon sequence and subsequent restriction fragment length polymorphism analysis. J Clin Microbiol. 2003 Jul;41(7):3147-53.

8542.  Sarker CB, Momen A, Jamal MF, Siddiqui NI, Siddiqui FM, Chowdhury KS, Rahman S, Talukder SI. Immunochromatographic (rK39) strip test in the diagnosis of visceral leishmaniasis in Bangladesh. Mymensingh Med J. 2003 Jul;12(2):93-7.


8543.  Cupolillo E, Brahim LR, Toaldo CB, de Oliveira-Neto MP, de Brito ME, Falqueto A, de Farias Naiff M, Grimaldi G Jr.  Genetic polymorphism and molecular epidemiology of Leishmania (Viannia) braziliensis from different hosts and geographic areas in Brazil. J Clin Microbiol. 2003 Jul;41(7):3126-32.

8544.  Singh N, Singh RT, Sundar S. Novel mechanism of drug resistance in kala azar field isolates. J Infect Dis. 2003 Aug 15;188(4):600-7. Epub 2003 Jul 29.

8545.  Spath GF, Garraway LA, Turco SJ, Beverley SM. The role(s) of lipophosphoglycan (LPG) in the establishment of Leishmania major infections in mammalian hosts. Proc Natl Acad Sci U S A. 2003 Aug 5;100(16):9536-41. Epub 2003 Jul 17.

8546.  Talukder SI, Huq MH, Rahman S, Haque MA, Sarker CB, Ali MS. Epidemiological characteristics of sixty five cases of Kala-azar attending to a laboratory in Mymensingh. Mymensingh Med J. 2003 Jul;12(2):89-92.


8547.  Bourreau E, Pascalis H, Prevot G, Kariminia A, Jolly N, Milon G, Buffet P, Michel R, Meynard JB, Boutin JP, Aschimoff D, Launois P. Increased production of interferon-gamma by Leishmania homologue of the mammalian receptor for activated C kinase-reactive CD4+ T cells among human blood mononuclear cells: an early marker of exposure to Leishmania?  Scand J Immunol. 2003 Aug;58(2):201-10.


8548.  Mendez S, Tabbara K, Belkaid Y, Bertholet S, Verthelyi D, Klinman D, Seder RA, Sacks DL. Coinjection with CpG-containing immunostimulatory oligodeoxynucleotides reduces the pathogenicity of a live vaccine against cutaneous Leishmaniasis but maintains its potency and durability. Infect Immun. 2003 Sep;71(9):5121-9.


APRIL, 2004

Diagnosis, Diagnostics, Immunodiagnosis & Immunodiagnostics:

9205.  Harith A, Mutasim M, Mansour D, Fadil Mustafa E, Arvidson H. Use of glycerol as an alternative to freeze-drying for long-term preservation of antigen for the direct agglutination test. Trop Med Int Health. 2003 Nov;8(11):1025-9.

9206.  Kopterides P, Halikias S, Tsavaris N. Visceral leishmaniasis masquerading as myelodysplasia. Am J Hematol. 2003 Nov;74(3):198-9.

9207.  Lala S, Nandy AK, Mahato SB, Basu MK: Delivery in vivo of 14-deoxy-11-oxandrographolide, an antileishmanial agent, by different  drug carriers.  Indian J Biochem Biophys 2003; 40(3): 169-74.

9208.  Pantsari MW, Coleman TA. Images in clinical medicine. Kala-azar. N Engl J Med. 2003 Oct 2;349(14):e13.

9209.  Salotra P, Sreenivas G, Beena KR, Mukherjee A, Ramesh V. Parasite detection in patients with post kala-azar dermal leishmaniasis in India: a comparison between molecular and immunological methods. J Clin Pathol. 2003 Nov;56(11):840-3.


9210.  Iannello D, Arena A, Buemi C, Calapai M, Stassi G, Gazzara D, Mastroeni P.  Differential induction of TNFalpha and IL-18 in human peripheral blood mononuclear cells infected with Leishmania major or Leishmania donovani. New Microbiol. 2003 Oct;26(4):399-404.


9211.  Mahmoodi M, Khamesipour A, Dowlati Y, Rafati S, Momeni AZ, Emamjomeh M, Hejazi H, Modabber F. Immune response measured in human volunteers vaccinated with autoclaved Leishmania major vaccine mixed with low dose of BCG. Clin Exp Immunol. 2003 Nov;134(2):303-8.


9212.  Berman J. Current treatment approaches to leishmaniasis. Curr Opin Infect Dis. 2003 Oct;16(5):397-401. Review.

9213.  Fernandez Cotarelo MJ, Abellan Martinez J, Guerra Vales JM, Martinez Sanchez P, Rodrigo Gomez De La Barcena M, Salto Fernandez E. Effect of highly active antiretroviral therapy on the incidence and clinical manifestations of visceral leishmaniasis in human immunodeficiency virus-infected patients. Clin Infect Dis. 2003 Oct 1;37(7):973-7. Epub 2003 Sep 10.


JULY, 2004


Diagnosis, Diagnostics, Immunodiagnosis & Immunodiagnostics:

9896.  Allahverdiyev AM, Uzun S, Bagirova M, Durdu M, Memisoglu HR. A sensitive new microculture method for diagnosis of cutaneous leishmaniasis. Am J Trop Med Hyg. 2004 Mar;70(3):294-7.

9897. Cortes S, Rolao N, Ramada J, Campino L. PCR as a rapid and sensitive tool in the diagnosis of human and canine leishmaniasis using Leishmania donovani s.l.-specific kinetoplastid primers. Trans R Soc Trop Med Hyg. 2004 Jan;98(1):12-7.

9898. Costa DJ, Favali C, Clarencio J, Afonso L, Conceicao V, Miranda JC, Titus RG, Valenzuela J, Barral-Netto M, Barral A, Brodskyn CI.  Lutzomyia longipalpis salivary gland homogenate impairs cytokine production and costimulatory molecule expression on human monocytes and dendritic cells. Infect Immun. 2004 Mar;72(3):1298-305.

9899. Hailu A, Pater JM, Kager PA, van der Poll T. Increased expression of HIV co-receptor CXCR4 on CD4+ T-cells in patients with active visceral leishmaniasis. Scand J Infect Dis. 2004;36(1):56-8.

9900. Islam MZ, Itoh M, Mirza R, Ahmed I, Ekram AR, Sarder AH, Shamsuzzaman SM, Hashiguchi Y, Kimura E. Direct agglutination test with urine samples for the diagnosis of visceral leishmaniasis. Am J Trop Med Hyg. 2004 Jan;70(1):78-82.

9901. Pal S, Aggarwal G, Haldar A, Majumdar A, Majumdar HK, Duttagupta S.  Diagnosis of symptomatic kala-azar by polymerase chain reaction using patient's blood. Med Sci Monit. 2004 Jan;10(1):MT1-5.

9902. Ravindran R, Anam K, Bairagi BC, Saha B, Pramanik N, Guha SK, Goswami RP, Banerjee D, Ali N. Characterization of immunoglobulin G and its subclass response to Indian kala-azar infection before and after chemotherapy. Infect Immun. 2004 Feb;72(2):863-70.

9903. Riera C, Fisa R, Udina M, Gallego M, Portus M. Detection of Leishmania infantum cryptic infection in asymptomatic blood donors living in an endemic area (Eivissa, Balearic Islands, Spain) by different diagnostic methods. Trans R Soc Trop Med Hyg. 2004 Feb;98(2):102-10.

9904. Wortmann GW, Romero LI, Paz HM, Ortega-Barria E, Bayard V, Hochberg LP, Ryan JR. Real-time polymerase chain reaction diagnosis of leishmaniasis in Panama from both fresh and frozen tissue. Trans R Soc Trop Med Hyg. 2004 Mar;98(3):148-51.


9905.  Amprey JL, Spath GF, Porcelli SA. Inhibition of CD1 expression in human dendritic cells during intracellular infection with Leishmania donovani. Infect Immun. 2004 Jan;72(1):589-92.

9906. Colmenares M, Corbi AL, Turco SJ, Rivas L. The dendritic cell receptor DC-SIGN discriminates among species and life cycle forms of Leishmania. J Immunol. 2004 Jan 15;172(2):1186-90.

9907. Maes L, Vanden Berghe D, Germonprez N, Quirijnen L, Cos P, De Kimpe N, Van Puyvelde L. In vitro and in vivo activities of a triterpenoid saponin extract (PX-6518) from the plant Maesa balansae against visceral leishmania species. Antimicrob Agents Chemother. 2004 Jan;48(1):130-6.

9908. Milleron RS, Mutebi JP, Valle S, Montoya A, Yin H, Soong L, Lanzaro GC. Antigenic diversity in maxadilan, a salivary protein from the sand fly vector of American visceral leishmaniasis. Am J Trop Med Hyg. 2004 Mar;70(3):286-93.

9909. Nylen S, Maasho K, McMahon-Pratt D, Akuffo H. Leishmanial amastigote antigen P-2 induces major histocompatibility complex class II-dependent natural killer-cell reactivity in cells from healthy donors. Scand J Immunol. 2004 Mar;59(3):294-304.

9910. Tintaya KW, Ying X, Dedet JP, Rijal S, De Bolle X, Dujardin JC. Antigen genes for molecular epidemiology of leishmaniasis: polymorphism of cysteine proteinase B and surface metalloprotease glycoprotein 63 in the Leishmania donovani complex. J Infect Dis. 2004 Mar 15;189(6):1035-43.

Vaccines :

9911.   Das P. Infectious disease surveillance update. Lancet Infect Dis. 2004 Feb;4(2):69.

Therapy :

9912. Nylen S, Maasho K, McMahon-Pratt D, Akuffo H. Leishmanial amastigote antigen P-2 induces major histocompatibility complex class II-dependent natural killer-cell reactivity in cells from healthy donors. Scand J Immunol. 2004 Mar;59(3):294-304.




Diagnosis, Diagnostics, Immunodiagnosis & Immunodiagnostics:

10540.  Bousoffara T, Louzir H, Ben Salah A, Dellagi K. Analysis of granzyme B activity as a surrogate marker of Leishmania-specific cell-mediated cytotoxicity in zoonotic cutaneous leishmaniasis. J Infect Dis. 2004 Apr 1;189(7):1265-73.

10541.  Martin-Sanchez J, Pineda JA, Morillas-Marquez F, Garcia-Garcia JA, Acedo C, Macias J. Detection of Leishmania infantum kinetoplast DNA in peripheral blood from asymptomatic individuals at risk for parenterally transmitted infections: relationship between polymerase chain reaction results and other Leishmania infection markers. Am J Trop Med Hyg. 2004 May;70(5):545-8.


10542.  Baldwin T, Henri S, Curtis J, O'Keeffe M, Vremec D, Shortman K, Handman E.  Dendritic cell populations in Leishmania major-infected skin and draining lymph nodes. Infect Immun. 2004 Apr;72(4):1991-2001.

10543.  Campbell K, Popov V, Soong L. Identification and molecular characterization of a gene encoding a protective Leishmania amazonensis Trp-Asp (WD) protein. Infect Immun. 2004 Apr;72(4):2194-202.

10544.  Schnur LF, Nasereddin A, Eisenberger CL, Jaffe CL, El Fari M, Azmi K, Anders G, Killick-Kendrick M, Killick-Kendrick R, Dedet JP, Pratlong F, Kanaan M, Grossman T, Jacobson RL, Schonian G, Warburg A.  Multifarious characterization of leishmania tropica from a Judean desert focus, exposing intraspecific diversity and incriminating phlebotomus sergenti as its vector. Am J Trop Med Hyg. 2004 Apr;70(4):364-72.

10545. Spath GF, Lye LF, Segawa H, Turco SJ, Beverley SM. Identification of a compensatory mutant (lpg2-REV) of Leishmania major able to survive as amastigotes within macrophages without LPG2-dependent glycoconjugates and its significance to virulence and immunization strategies. Infect Immun. 2004 Jun;72(6):3622-7.

10546. Ya'ari A, Jaffe CL, Garty BZ. Visceral leishmaniasis in Israel, 1960-2000. Isr Med Assoc J. 2004 Apr;6(4):205-8.


10547.  Stix G. Making drugs, not profits. Sci Am. 2004 May;290(5):42-4.