Diagnosis, Diagnostics, Immunodiagnosis & Immunodiagnostics:

8488.  Abbate I, Romano M, Longo R, Cappiello G, Lo Iacono O, Di Marco V, Paparella C, Spano A, Capobianchi MR. Endogenous levels of mRNA for IFNs and IFN-related genes in hepatic biopsies of chronic HCV-infected and non-alcoholic steatohepatitis patients. J Med Virol. 2003 Aug;70(4):581-7.

8489.  Bergeron KG, Bonebrake RG, Allen C, Gray CJ. Latent tuberculosis in pregnancy: screening and treatment. Curr Womens Health Rep. 2003 Aug;3(4):303-8.

8490.  Bhattacharya R, Bhattacharya S, Wenzel-Mathers M , Buckwold VE. Phyllanthus amarus root clone with significant activity against bovine viral diarrhoea virus-asurrogate model of hepatitis C Virus.  Curr Sci 2003; 84(4): 529-33.

8491.  Busch MP, Tobler LH, Gerlich WH, Schaefer S, Giachetti C, Smith R. Very low level viremia in bHCV infectious unit missed by NAT. Transfusion. 2003 Aug;43(8):1173-4.

8492.  Czaja AJ, Shums Z, Binder WL, Lewis SJ, Nelson VJ, Norman GL. Frequency and significance of antibodies to chromatin in autoimmune hepatitis. Dig Dis Sci. 2003 Aug;48(8):1658-64.

8493.  Freeman AJ, Law MG, Kaldor JM, Dore GJ. Predicting progression to cirrhosis in chronic hepatitis C virus infection. J Viral Hepat. 2003 Jul;10(4):285-93.

8494.  Furne JK, Springfield JR, Ho SB, Levitt MD. Simplification of the end-alveolar carbon monoxide technique to assess erythrocyte survival. J Lab Clin Med. 2003 Jul;142(1):52-7.

8495.  Glebe D, Aliakbari M, Krass P, Knoop EV, Valerius KP, Gerlich WH. Pre-s1 antigen-dependent infection of Tupaia hepatocyte cultures with human hepatitis B virus. J Virol. 2003 Sep;77(17):9511-21.

8496.  Gregorio GV, Choudhuri K, Ma Y, Pensati P, Iorio R, Grant P, Garson J, Bogdanos DP, Vegnente A, Mieli-Vergani G, Vergani D. Mimicry between the hepatitis C virus polyprotein and antigenic targets of nuclear and smooth muscle antibodies in chronic hepatitis C virus infection. Clin Exp Immunol. 2003 Sep;133(3):404-13.

8497.  Gupta S, Bent S, Kohlwes J. Test characteristics of alpha-fetoprotein for detecting hepatocellular carcinoma in patients with hepatitis C. A systematic review and critical analysis. Ann Intern Med. 2003 Jul 1;139(1):46-50.

8498.  Huang YH, Wu JC, Chang TT, Sheen IJ, Lee PC, Huo TI, Su CW, Wang YJ, Chang FY, Lee SD. Analysis of clinical, biochemical and viral factors associated with early relapse after lamivudine treatment for hepatitis B e antigen-negative chronic hepatitis B patients in Taiwan. J Viral Hepat. 2003 Jul;10(4):277-84.

8499.  Iavarone M, Lampertico P, Seletti C, Francesca Donato M, Ronchi G, del Ninno E, Colombo M. The clinical and pathogenetic significance of estrogen receptor-beta expression in chronic liver diseases and liver carcinoma. Cancer. 2003 Aug 1;98(3):529-34.

8500.  Jamal MM, Abdelkarim BZ. Chronic hepatitis C with persistently normal aminotransferase levels: do we have an adequate definition? Am J Gastroenterol. 2003 Jul;98(7):1455-6.

8501.  Judd A, Parry J, Hickman M, McDonald T, Jordan L, Lewis K, Contreras M, Dusheiko G, Foster G, Gill N, Kemp K, Main J, Murray-Lyon I, Nelson M. Evaluation of a modified commercial assay in detecting antibody to hepatitis C virus in oral fluids and dried blood spots. J Med Virol. 2003 Sep;71(1):49-55.

8502.  Kwun HJ, Jang KL. Dual effects of hepatitis C virus Core protein on the transcription of cyclin-dependent kinase inhibitor p21 gene. J Viral Hepat. 2003 Jul;10(4):249-55.

8503.  Kyrlagkitsis I, Portmann B, Smith H, O'Grady J, Cramp ME. Liver histology and progression of fibrosis in individuals with chronic hepatitis C and persistently normal ALT. Am J Gastroenterol. 2003 Jul;98(7):1588-93.

8504.  Laperche S, Le Marrec N, Simon N, Bouchardeau F, Defer C, Maniez-Montreuil M, Levayer T, Zappitelli JP, Lefrere JJ. A new HCV core antigen assay based on disassociation of immune complexes: an alternative to molecular biology in the diagnosis of early HCV infection. Transfusion. 2003 Jul;43(7):958-62.

8505.  Lau DT, Ma H, Lemon SM, Doo E, Ghany MG, Miskovsky E, Woods GL, Park Y, Hoofnagle JH. A rapid immunochromatographic assay for hepatitis B virus screening. J Viral Hepat. 2003 Jul;10(4):331-4.

8506.  Leonardi S, La Spina M, La Rosa M, Schiliro G.  Prolylhydroxylase and procollagen type III in long-term survivors of acute lymphoblastic leukemia (ALL): a biochemical approach to HCV-related liver disease. Med Pediatr Oncol. 2003 Jul;41(1):17-20.

8507.  Loguercio C, Cuomo A, Tuccillo C, Gazzerro P, Cioffi M, Molinari AM, Del Vecchio Blanco C. Liver p53 expression in patients with HCV-related chronic hepatitis. J Viral Hepat. 2003 Jul;10(4):266-70.

8508.  Ma SY, Au WY, Ng IO, Lie AK, Leung AY, Liang RH, Lau GK, Kwong YL.  Role of liver biopsy in the management of liver dysfunction after hematopoietic stem-cell transplantation in a hepatitis B virus-prevalent patient population. Transplantation. 2003 Jul 15;76(1):169-76.

8509.  Marsden PA, Ning Q, Fung LS, Luo X, Chen Y, Mendicino M, Ghanekar A, ScottJA, Miller T, Chan CW, Chan MW, He W, Gorczynski RM, Grant DR, Clark DA, Phillips MJ, Levy GA. The Fgl2/fibroleukin prothrombinase contributes to immunologically mediated thrombosis in experimental and human viral hepatitis. J Clin Invest. 2003 Jul;112(1):58-66.

8510.  Matsuoka S, Tsurui H, Abe M, Terashima K, Nakamura K, Hamano Y, Ohtsuji M, Honma N, Serizawa I, Ishii Y, Takiguchi M, Hirose S, Shirai T. A monoclonal antibody to the alpha2 domain of murine major histocompatibility complex class I that specifically kills activated lymphocytes and blocks liver damage in the concanavalin A hepatitis model. J Exp Med. 2003 Aug 4;198(3):497-503. Epub 2003 Jul 28.

8511.  Maynard M, Pradat P, Berthillon P, Picchio G, Voirin N, Martinot M, Marcellin P, Trepo C. Clinical relevance of total HCV core antigen testing for hepatitis C monitoring and for predicting patients' response to therapy. J Viral Hepat. 2003 Jul;10(4):318-23.

8512.  Nishie A, Yoshimitsu K, Irie H, Yoshitake T, Aibe H, Tajima T, Shinozaki K, Nakayama T, Kakihara D, Matsuura T, Takahashi M, Kamochi N, Onitsuka H, Honda H. Fitz-Hugh-Curtis syndrome. Radiologic manifestation. J Comput Assist Tomogr. 2003 Sep-Oct;27(5):786-91.

8513.  Pham BN, Martinot-Peignoux M, Valla D, Dubois S, Degott C, Mosnier JF. Differential expression of perforin and granzyme B in the liver of patients with chronic hepatitis C. Hum Pathol. 2003 Aug;34(8):770-7.

8514.  Poynard T, McHutchison J, Manns M, Myers RP, Albrecht J. Biochemical surrogate markers of liver fibrosis and activity in a randomized trial of peginterferon alfa-2b and ribavirin. Hepatology. 2003 Aug;38(2):481-92.

8515.  Rahaman QM, Nath NC, Midya S. Hepatic tuberculosis.  J Indian Med Ass 2002; 100(8): 522-3.

8516.  Robertson P, Beynon S, Whybin R, Brennan C, Vollmer-Conna U, Hickie I, Lloyd A.  Measurement of EBV-IgG anti-VCA avidity aids the early and reliable diagnosis of primary EBV infection. J Med Virol. 2003 Aug;70(4):617-23.

8517.  Rokuhara A, Tanaka E, Matsumoto A, Kimura T, Yamaura T, Orii K, Sun X, Yagi S, Maki N, Kiyosawa K. Clinical evaluation of a new enzyme immunoassay for hepatitis B virus core-related antigen; a marker distinct from viral DNA for monitoring lamivudine treatment. J Viral Hepat. 2003 Jul;10(4):324-30.

8518.  Sreekumar R, Rosado B, Rasmussen D, Charlton M. Hepatic gene expression in histologically progressive nonalcoholic steatohepatitis. Hepatology. 2003 Jul;38(1):244-51.

8519.  Tedeschi R, Pivetta E, Zanussi S, Bidoli E, Ros M, di Gennaro G, Nasti G, De Paoli P.  Quantification of hepatitis C virus (HCV) in liver specimens and sera from patients with human immunodeficiency virus coinfection by using the Versant HCV RNA 3.0 (branched DNA-based) DNA assay. J Clin Microbiol. 2003 Jul;41(7):3046-50.


8520.  Auer J, Berent R, Eber B. Hepatitis A virus seropositivity and coronary artery disease. Circulation. 2003 Jul 8;108(1):e8.

8521.  Cao J, Zhao P, Zhao LJ, Wu SM, Zhu SY, Qi ZT. Identification and expression of human CD81 gene on murine NIH/3T3 cell membrane. J Microbiol Methods. 2003 Jul;54(1):81-5.

8522.  Chironna M, Grottola A, Lanave C, Villa E, Barbuti S, Quarto M.   Genetic analysis of HAV strains recovered from patients with acute hepatitis from Southern Italy. J Med Virol. 2003 Jul;70(3):343-9.

8523.  Chung TW, Lee YC, Ko JH, Kim CH.  Hepatitis B Virus X protein modulates the expression of PTEN by inhibiting the function of p53, a transcriptional activator in liver cells. Cancer Res. 2003 Jul 1;63(13):3453-8.

8524.  Herzer K, Falk CS, Encke J, Eichhorst ST, Ulsenheimer A, Seliger B, Krammer PH.  Upregulation of major histocompatibility complex class I on liver cells by hepatitis C virus core protein via p53 and TAP1 impairs natural killer cell cytotoxicity. J Virol. 2003 Aug;77(15):8299-309.

8525.  Horikawa I, Barrett JC. Transcriptional regulation of the telomerase hTERT gene as a target for cellular and viral oncogenic mechanisms. Carcinogenesis. 2003 Jul;24(7):1167-76. Epub 2003 May 22.

8526.  Kaplan M, Gawrieh S, Cotler SJ, Jensen DM. Neutralizing antibodies in hepatitis C virus infection: a review of immunological and clinical characteristics. Gastroenterology. 2003 Aug;125(2):597-604.

8527.  Lyons AJ, Robertson HD. Detection of tRNA-like structure through RNase P cleavage of viral internal ribosome entry site RNAs near the AUG start triplet. J Biol Chem. 2003 Jul 18;278(29):26844-50. Epub 2003 May 12.

8528.  Ribeiro RM, Layden-Almer J, Powers KA, Layden TJ, Perelson AS. Dynamics of alanine aminotransferase during hepatitis C virus treatment. Hepatology. 2003 Aug;38(2):509-17.

8529.  Rigamonti C, Mottaran E, Reale E, Rolla R, Cipriani V, Capelli F, Boldorini R, Vidali M, Sartori M, Albano E. Moderate alcohol consumption increases oxidative stress in patients with chronic hepatitis C. Hepatology. 2003 Jul;38(1):42-9.

8530.  Schvoerer E, Navas MC, Thumann C, Fuchs A, Meyer N, Habersetzer F, Stoll-Keller F.  Production of interleukin-18 and interleukin-12 in patients suffering from chronic hepatitis C virus infection before antiviral therapy. J Med Virol. 2003 Aug;70(4):588-93.

8531.  Trendelenburg M, Schifferli JA.  Cryoglobulins in chronic hepatitis C virus infection. Clin Exp Immunol. 2003 Aug;133(2):153-5.

8532.  Yamaura T, Tanaka E, Matsumoto A, Rokuhara A, Orii K, Yoshizawa K, Miyakawa Y, Kiyosawa K.  A case-control study for early prediction of hepatitis B e antigen seroconversion by hepatitis B virus DNA levels and mutations in the precore region and core promoter. J Med Virol. 2003 Aug;70(4):545-52.

8533.  Yuste JR, Prieto J. Anticardiolipin antibodies in chronic viral hepatitis. Do they have clinical consequences?  Eur J Gastroenterol Hepatol. 2003 Jul;15(7):717-9.


8534.  Kaplan M, Gawrieh S, Cotler SJ, Jensen DM. Neutralizing antibodies in hepatitis C virus infection: a review of immunological and clinical characteristics. Gastroenterology. 2003 Aug;125(2):597-604.


8535.  Ezaki T, Ikegami T, Ishida T, Aimitsu S, Mori M, Fujihara M.  Significance of thymidine phosphorylase in HCC with chronic liver disease for long-term postoperative recurrence. J Surg Oncol. 2003 Jul;83(3):173-9; discussion 179.

8536.  Kaplan M, Gawrieh S, Cotler SJ, Jensen DM. Neutralizing antibodies in hepatitis C virus infection: a review of immunological and clinical characteristics. Gastroenterology. 2003 Aug;125(2):597-604.

8537.  Zhang W, Hacker HJ, Tokus M, Bock T, Schroder CH.  Patterns of circulating hepatitis B virus serum nucleic acids during lamivudine therapy. J Med Virol. 2003 Sep;71(1):24-30.

APRIL, 2004

Diagnosis, Diagnostics, Immunodiagnosis & Immunodiagnostics:

9125.  Adinolfi LE. Prevalence and incidence of cryoglobulins in chronic hepatitis C patients. Am J Gastroenterol. 2003 Nov;98(11):2568-9; author reply 2569-70.

9126.  Annet L, Materne R, Danse E, Jamart J, Horsmans Y, Van Beers BE. Hepatic flow parameters measured with MR imaging and Doppler US: correlations with degree of cirrhosis and portal hypertension. Radiology. 2003 Nov;229(2):409-14. Epub 2003 Sep 11.

9127.  Bai YJ, Zhao JR, Lv GT, Zhang WH, Wang Y, Yan XJ. Rapid and high throughput detection of HBV YMDD mutants with fluorescence polarization. World J Gastroenterol. 2003 Oct;9(10):2344-7.

9128.  Bajaj J, Knox JF, Komorowski R, Saeian K. The irony of herbal hepatitis: Ma-Huang-induced hepatotoxicity associated with compound heterozygosity for hereditary hemochromatosis. Dig Dis Sci. 2003 Oct;48(10):1925-8.

9129.  Barth H, Schafer C, Adah MI, Zhang F, Linhardt RJ, Toyoda H, Kinoshita-Toyoda A, Toida T, Van Kuppevelt TH, Depla E, Von Weizsacker F, Blum HE, Baumert TF.  Cellular binding of hepatitis C virus envelope glycoprotein E2 requires cell surface heparan sulfate. J Biol Chem. 2003 Oct 17;278(42):41003-12. Epub 2003 Jul 16.

9130.  Batey RG. Chronic hepatitis C. Aust Fam Physician. 2003 Oct;32(10):807-11.

9131.  Bedossa P, Dargere D, Paradis V. Sampling variability of liver fibrosis in chronic hepatitis C. Hepatology. 2003 Dec;38(6):1449-57.

9132.  Bonacchi A, Petrai I, Defranco RM, Lazzeri E, Annunziato F, Efsen E, Cosmi L, Romagnani P, Milani S, Failli P, Batignani G, Liotta F, Laffi G, Pinzani M, Gentilini P, Marra F. The chemokine CCL21 modulates lymphocyte recruitment and fibrosis in chronic hepatitis C. Gastroenterology. 2003 Oct;125(4):1060-76.

9133.  Brook MG, Gilson R, Wilkins EL; British HIV Association. BHIVA Guidelines: coinfection with HIV and chronic hepatitis B virus. HIV Med. 2003 Oct;4 Suppl 1:42-51.

9134.  Castera L, Pawlotsky JM, Dhumeaux D. Worsening of steatosis and fibrosis progression in hepatitis C. Gut. 2003 Oct;52(10):1531.

9135.  Chaudhuri V, Nanu A, Panda SK, Chand P. Evaluation of serologic screening of blood donors in India reveals a lack of correlation between anti-HBc titer and PCR-amplified HBV DNA. Transfusion. 2003 Oct;43(10):1442-8.

9136.  Choi S. Nefazodone (Serzone) withdrawn because of hepatotoxicity. CMAJ. 2003 Nov 25;169(11):1187.

9137.  Cortez-Pinto H, Baptista A, Camilo ME, De Moura MC. Nonalcoholic steatohepatitis--a long-term follow-up study: comparison with alcoholic hepatitis in ambulatory and hospitalized patients. Dig Dis Sci. 2003 Oct;48(10):1909-13.

9138.  De Ridder RJ, Stronkhorst A. Effect of long-term lamivudine therapy on histological outcome in chronic hepatitis B. Gastroenterology. 2003 Oct;125(4):1286-7;

9139.  Dore GJ, MacDonald M, Law MG, Kaldor JM. Epidemiology of hepatitis C virus infection in Australia. Aust Fam Physician. 2003 Oct;32(10):796-8.

9140.  Goolsby MJ. Screening, diagnosis, and monitoring of hepatic injury. J Am Acad Nurse Pract. 2003 Oct;15(10):434-7.

9141.  Halfon P, Khiri H, Tran A, Penaranda G, Courcambeck J, Joly H, Ouzan D. Hepatitis C virus RNA load in relapsed patients: week two of treatment is the best time to predict the complete response. Eur J Gastroenterol Hepatol. 2003 Oct;15(10):1067-71.

9142.  Hou CS, Wang GQ, Lu SL, Yue B, Li MR, Wang XY, Yu JW. Role of activation-induced cell death in pathogenesis of patients with chronic hepatitis B. World J Gastroenterol. 2003 Oct;9(10):2356-8.

9143.  Johanson FD, Balliram DB. Successful treatment of hepatitis C in a patient with advanced AIDS and decompensated cirrhosis. AIDS Read. 2003 Oct;13(10):494-6, 500-1.

9144.  Kiyici M, Gurel S, Budak F, Dolar E, Gulten M, Nak SG, Memik F. Fas antigen (CD95) expression and apoptosis in hepatocytes of patients with chronic viral hepatitis. Eur J Gastroenterol Hepatol. 2003 Oct;15(10):1079-84.

9145.  Laine S, Thouard A, Derancourt J, Kress M, Sitterlin D, Rossignol JM. In vitro and in vivo interactions between the hepatitis B virus protein P22 and the cellular protein gC1qR. J Virol. 2003 Dec;77(23):12875-80.

9146.  Liu CJ, Kao JH, Chen DS. Molecular assays for hepatitis B virus infection. Hepatology. 2003 Nov;38(5):1311.

9147.  Malaty HM, Tanaka E, Kumagai T, Ota H, Kiyosawa K, Graham DY, Katsuyama T.  Seroepidemiology of Helicobacter pylori and hepatitis A virus and the mode of transmission of infection: a 9-year cohort study in rural Japan. Clin Infect Dis. 2003 Oct 15;37(8):1067-72. Epub 2003 Sep 23.

9148.  Manesis EK, Papatheodoridis GV, Sevastianos V, Cholongitas E, Papaioannou C, Hadziyannis SJ. Significance of hepatitis B viremia levels determined by a quantitative polymerase chain reaction assay in patients with hepatitis B e antigen-negative chronic hepatitis B virus infection. Am J Gastroenterol. 2003 Oct;98(10):2261-7.

9149.  Mathurin P, Abdelnour M, Ramond MJ, Carbonell N, Fartoux L, Serfaty L, Valla D, Poupon R, Chaput JC, Naveau S. Early change in bilirubin levels is an important prognostic factor in severe alcoholic hepatitis treated with prednisolone. Hepatology. 2003 Dec;38(6):1363-9.

9150.  Mondelli  MU, Cerino A, Meola A, Nicosia A Variability or conservation of hepatitis C virus hypervariable region 1? Implications for immune responses.  J Biosci, Bangalore 2003; 28(3): 305-10.

9151.  Nevens F, Roskams T, Van Vlierberghe H, Horsmans Y, Sprengers D, Elewaut A, Desmet V, Leroux-Roels G, Quinaux E, Depla E, Dincq S, Vander Stichele C, Maertens G, Hulstaert F.  A pilot study of therapeutic vaccination with envelope protein E1 in 35 patients with chronic hepatitis C. Hepatology. 2003 Nov;38(5):1289-96.

9152.  Operskalski EA, Mosley JW, Tobler LH, Fiebig EW, Nowicki MJ, Mimms LT, Gallarda J, Phelps BH, Busch MP; Transfusion-Transmitted Viruses Study; Retrovirus Epidemiology Donor Study. HCV viral load in anti-HCV-reactive donors and infectivity for their recipients. Transfusion. 2003 Oct;43(10):1433-41.

9153.  Petit MA, Jolivet-Reynaud C, Peronnet E, Michal Y, Trepo C. Mapping of a conformational epitope shared between E1 and E2 on the serum-derived human hepatitis C virus envelope. J Biol Chem. 2003 Nov 7;278(45):44385-92. Epub 2003 Jul 24.

9154.  Pisani G, Cristiano K, Bisso G, Wirz M, Mele C, Gentili G. HBV DNA in plasma pools fractionation. Transfusion. 2003 Dec;43(12):1763-4.

9155.  Ren F, Hino K, Yamaguchi Y, Funatsuki K, Hayashi A, Ishiko H, Furutani M, Yamasaki T, Korenaga K, Yamashita S, Konishi T, Okita K. Cytokine-dependent anti-viral role of CD4-positive T cells in therapeutic vaccination against chronic hepatitis B viral infection. J Med Virol. 2003 Nov;71(3):376-84.

9156.  Rubinstein ML, Miele ME.   Hepatitis C virus infection: detection and treatment. Clin Lab Sci. 2003 Fall;16(4):203-8. Review.

9157.  Safadi R, Israeli E, Papo O, Shibolet O, Melhem A, Bloch A, Rowe M, Alper R, Klein A, Hemed N, Segol O, Thalenfeld B, Engelhardt D, Rabbani E, Ilan Y. Treatment of chronic hepatitis B virus infection via oral immune regulation toward hepatitis B virus proteins. Am J Gastroenterol. 2003 Nov;98(11):2505-15.

9158.  Smith MW, Yue ZN, Korth MJ, Do HA, Boix L, Fausto N, Bruix J, Carithers RL Jr, Katze MG. Hepatitis C virus and liver disease: global transcriptional profiling and identification of potential markers. Hepatology. 2003 Dec;38(6):1458-67.

9159.  Sterling RK.  Triple infection with human immunodeficiency virus, hepatitis C virus, and hepatitis B virus: a clinical challenge. Am J Gastroenterol. 2003 Oct;98(10):2130-4.

9160.  Tao J, Peng HQ, Cai WM, Dong FQ, Weng HL, Liu RH.  Influence factors of serum fibrosis markers in liver fibrosis. World J Gastroenterol. 2003 Nov;9(11):2497-500.

9161.  Vogt S, Schneider-Stock R, Klauck S, Roessner A, Rocken C. Detection of hepatitis C virus RNA in formalin-fixed, paraffin-embedded thin-needle liver biopsy specimens. Am J Clin Pathol. 2003 Oct;120(4):536-43.

9162.  Wong JB, Davis GL, McHutchison JG, Manns MP, Albrecht JK; International Hepatitis Interventional Therapy Group. Economic and clinical effects of evaluating rapid viral response to peginterferon alfa-2b plus ribavirin for the initial treatment of chronic hepatitis C. Am J Gastroenterol. 2003 Nov;98(11):2354-62.

9163.  Xu B, Broome U, Uzunel M, Nava S, Ge X, Kumagai-Braesch M, Hultenby K, Christensson B, Ericzon BG, Holgersson J, Sumitran-Holgersson S. Capillarization of hepatic sinusoid by liver endothelial cell-reactive autoantibodies in patients with cirrhosis and chronic hepatitis. Am J Pathol. 2003 Oct;163(4):1275-89.


9164.  Ahn SH, Kramvis A, Kawai S, Spangenberg HC, Li J, Kimbi G, Kew M, Wands J, Tong S.  Sequence variation upstream of precore translation initiation codon reduces hepatitis B virus e antigen production. Gastroenterology. 2003 Nov;125(5):1370-8.

9165.  Armstrong GL. Commentary: Modelling the epidemiology of hepatitis C and its complications. Int J Epidemiol. 2003 Oct;32(5):725-6.

9166.  Barrett S, Collins M, Kenny C, Ryan E, Keane CO, Crowe J. Polymorphisms in tumour necrosis factor-alpha, transforming growth factor-beta, interleukin-10, interleukin-6, interferon-gamma, and outcome of hepatitis C virus infection. J Med Virol. 2003 Oct;71(2):212-8.

9167.  Boulestin A, Sandres-Saune K, Payen JL, Rostaing L, Pasquier C, Izopet J. Genetic heterogeneity of the NS5A gene of hepatitis C virus and early response to interferon-alpha. J Infect Dis. 2003 Nov 1;188(9):1367-70. Epub 2003 Oct 13.

9168.  Chiavetta JA, Escobar M, Newman A, He Y, Driezen P, Deeks S, Hone DE, O'Brien SF, Sher G. Incidence and estimated rates of residual risk for HIV, hepatitis C, hepatitis B and human T-cell lymphotropic viruses in blood donors in Canada, 1990-2000. CMAJ. 2003 Oct 14;169(8):767-73.

9169.  De Ridder RJ, Stronkhorst A. Effect of long-term lamivudine therapy on histological outcome in chronic hepatitis B. Gastroenterology. 2003 Oct;125(4):1286-7;

9170.  Franco S, Gimenez-Barcons M, Puig-Basagoiti F, Furcic I, Sanchez-Tapias JM, Rodes J, Saiz JC. Characterization and evolution of NS5A quasispecies of hepatitis C virus genotype 1b in patients with different stages of liver disease. J Med Virol. 2003 Oct;71(2):195-204.

9171.  Fujioka S, Shimomura H, Iwasaki Y, Fujio K, Nakagawa H, Onishi Y, Takagi S, Taniguchi H, Umeoka F, Nakajima H, Moriya A, Nanba K, Piao CY, Shinji T, Koide N, Shiratori Y. Hepatitis B virus gene in liver tissue promotes hepatocellular carcinoma development in chronic hepatitis C patients. Dig Dis Sci. 2003 Oct;48(10):1920-4.

9172.  Gaya DR, Thorburn D, Oien KA, Morris AJ, Stanley AJ. Hepatic granulomas: a 10 year single centre experience. J Clin Pathol. 2003 Nov;56(11):850-3.

9173.  Giannini E, Botta F, Borro P, Malfatti F, Fumagalli A, Testa E, Podesta E, Chiarbonello B, Polegato S, Mamone M, Testa R. Relationship between thrombopoietin serum levels and liver function in patients with chronic liver disease related to hepatitis C virus infection. Am J Gastroenterol. 2003 Nov;98(11):2516-20.

9174.  Kong HJ, Park MJ, Hong S, Yu HJ, Lee YC, Choi YH, Cheong J. Hepatitis B virus X protein regulates transactivation activity and protein stability of the cancer-amplified transcription coactivator ASC-2. Hepatology. 2003 Nov;38(5):1258-66.

9175.  Lake-Bakaar G, Frost SD. Viral kinetics and hepatitis C. Hepatology. 2003 Dec;38(6):1588.

9176.  Law MG, Dore GJ, Bath N, Thompson S, Crofts N, Dolan K, Giles W, Gow P, Kaldor J, Loveday S, Powell E, Spencer J, Wodak A. Modelling hepatitis C virus incidence, prevalence and long-term sequelae in Australia, 2001. Int J Epidemiol. 2003 Oct;32(5):717-24.

9177.  Macnaughton TB, Li YI, Doughty AL, Lai MM. Hepatitis delta virus RNA encoding the large delta antigen cannot sustain replication due to rapid accumulation of mutations associated with RNA editing. J Virol. 2003 Nov;77(22):12048-56.

9178.  Matskevich AA, Strayer DS. Exploiting hepatitis C virus activation of NFkappaB to deliver HCV-responsive expression of interferons alpha and gamma. Gene Ther. 2003 Oct;10(22):1861-73.

9179.  Milich D, Liang TJ.  Exploring the biological basis of hepatitis B e antigen in hepatitis B virus infection. Hepatology. 2003 Nov;38(5):1075-86. Review.

9180.  Mueller T, Gessner R, Sarrazin C, Graf C, Halangk J, Witt H, Kottgen E, Wiedenmann B, Berg T. Apolipoprotein E4 allele is associated with poor treatment response in hepatitis C virus (HCV) genotype 1. Hepatology. 2003 Dec;38(6):1592;

9181.  Muhlbauer M, Bosserhoff AK, Hartmann A, Thasler WE, Weiss TS, Herfarth H, Lock G, Scholmerich J, Hellerbrand C. A novel MCP-1 gene polymorphism is associated with hepatic MCP-1 expression and severity of HCV-related liver disease. Gastroenterology. 2003 Oct;125(4):1085-93.

9182.  Ohata K, Ichikawa T, Nakao K, Shigeno M, Nishimura D, Ishikawa H, Hamasaki K, Eguchi K. Interferon alpha inhibits the nuclear factor kappa B activation triggered by X gene product of hepatitis B virus in human hepatoma cells. FEBS Lett. 2003 Oct 23;553(3):304-8.

9183.  Park SG, Lee SM, Jung G. Antisense oligodeoxynucleotides targeted against molecular chaperonin Hsp60 block human hepatitis B virus replication. J Biol Chem. 2003 Oct 10;278(41):39851-7. Epub 2003 Jul 16.

9184.  Risbud A, Pereira M, Meherdale S, Gangakhedkar R, Ghate M, Joshi S, Tripathy S.  Lack of evidence for sexual transmission of hepatitis C virus in patients attending STD clinics in Pune, India. Sex Transm Infect. 2003 Oct;79(5):425.

9185.  Rubinstein ML, Miele ME. Hepatitis C virus infection: detection and treatment. Clin Lab Sci. 2003 Fall;16(4):203-8. Review.

9186.  Schleicher SB, Flehmig BF. Genotyping of GB virus C by restriction pattern analysis of the 5' untranslated region. J Med Virol. 2003 Oct;71(2):226-32.

9187.  Steyaert S, Vanlandschoot P, Van Vlierberghe H, Diepolder H, Leroux-Roels G. Soluble CD14 levels are increased and inversely correlated with the levels of hepatitis B surface antigen in chronic hepatitis B patients. J Med Virol. 2003 Oct;71(2):188-94.

9188.  Watashi K, Hijikata M, Hosaka M, Yamaji M, Shimotohno K. Cyclosporin A suppresses replication of hepatitis C virus genome in cultured hepatocytes. Hepatology. 2003 Nov;38(5):1282-8.

9189.  Wright-Kanuth MS, Smith LA. Transfusion-transmitted viruses. Clin Lab Sci. 2003 Fall;16(4):221-9. Review.

9190.  Yeh CT, Hwang DR, Lai HY, Hsu JT. Inhibition of authentic hepatitis C virus replication by sodium stibogluconate. Biochem Biophys Res Commun. 2003 Oct 17;310(2):537-41.

9191.  Zuckerman E, Kessel A, Slobodin G, Sabo E, Yeshurun D, Toubi E.  Antiviral treatment down-regulates peripheral B-cell CD81 expression and CD5 expansion in chronic hepatitis C virus infection. J Virol. 2003 Oct;77(19):10432-6.

9192.  Zwahlen M, Vlahov D. Commentary: Modelling and understanding differences in human immunodeficiency and hepatitis C virus epidemiology in injection drug users. Int J Epidemiol. 2003 Oct;32(5):715-6.


9193.  Bardenheier B, Gonzalez IM, Washington ML, Bell BP, Averhoff F, Massoudi MS, Hyams I, Simard EP, Yusuf H. Parental knowledge, attitudes, and practices associated with not receiving hepatitis A vaccine in a demonstration project in Butte County, California. Pediatrics. 2003 Oct;112(4):e269.

9194.  Jacobs RJ, Meyerhoff AS.  Cost-effectiveness of hepatitis A/B vaccine versus hepatitis B vaccine in public sexually transmitted disease clinics. Sex Transm Dis. 2003 Nov;30(11):859-65.

9195.  Patrick DM, Bigham M, Ng H, White R, Tweed A, Skowronski DM. Elimination of acute hepatitis B among adolescents after one decade of an immunization program targeting Grade 6 students. Pediatr Infect Dis J. 2003 Oct;22(10):874-7.

9196.  Wang RX, Boland G, Guo Y, Lei SP, Yang CH, Chen J, Tian J, Wen JY, Du KH, van Hattum J, de Gast GC. Is a low dose of hepatitis B vaccine enough for a rapid vaccination scheme? World J Gastroenterol. 2003 Oct;9(10):2353-5.


9197.  Bernstein D. Cost-effectiveness of treatment for chronic hepatitis C infection. JAMA. 2003 Oct 15;290(15):1993;

9198.  De Ridder RJ, Stronkhorst A. Effect of long-term lamivudine therapy on histological outcome in chronic hepatitis B. Gastroenterology. 2003 Oct;125(4):1286-7.

9199.  Dietitians of Canada. Hepatitis C: nutrition care Canadian guidelines for health care providers. Can J Diet Pract Res. 2003 Fall;64(3):139-41.

9200.  Ghany MG, Kleiner DE. E1 therapeutic vaccination for chronic hepatitis C: all that glitters is not gold. Hepatology. 2003 Nov;38(5):1092-4. Review.

9201.  Hagmann S, Chung M, Rochford G, Jani M, Trinh-Shevrin C, Sitnitskaya Y, Neumann AU, Pollack H. Response to lamivudine treatment in children with chronic hepatitis B virus infection. Clin Infect Dis. 2003 Dec 1;37(11):1434-40. Epub 2003 Nov 06.

9202.  Nierengarten MB. Progress on the treatment of hepatitis C. Lancet Infect Dis. 2003 Dec;3(12):748.

9203.  Sidhu-Malik NK, Kaplan AL. Multiple fixed drug eruption with interferon/ribavirin combination therapy for hepatitis C virus infection. J Drugs Dermatol. 2003 Oct;2(5):570-3.  

9204. Zoulim F. Treatment of pre- and post-liver transplantation HBV infection: Should we aim at combination therapy? Hepatology. 2003 Dec;38(6):1353-5.


JULY, 2004

Diagnosis, Diagnostics, Immunodiagnosis & Immunodiagnostics:

9824.   Acosta-Rivero N, Duenas-Carrera S, Alvarez-Lajonchere L, Morales- Grillo J. HCV core protein-expressing DNA vaccine induces a strong class I-binding peptide DTH response in mice. Biochem Biophys Res Commun. 2004 Feb 13;314(3):781-6.

9825.   Amoroso P, Buonocore S, Lettieri G, Pierri P, Mele A. The clinical profile of acute hepatitis A infection: is it really so severe? Hepatology. 2004 Feb;39(2):572; author reply 572-3.

9826.   Canbay A, Friedman S, Gores GJ. Apoptosis: the nexus of liver injury and fibrosis. Hepatology. 2004 Feb;39(2):273-8. Review.

9827.   Cao Y, Hamada T, Matsui T, Date T, Iwabuchi K. Hepatitis C virus core protein interacts with p53-binding protein, 53BP2/Bbp/ASPP2, and inhibits p53-mediated apoptosis. Biochem Biophys Res Commun. 2004 Mar 19;315(4):788-95.

9828.   Chau TN, Lee KC, Yao H, Tsang TY, Chow TC, Yeung YC, Choi KW, Tso YK, Lau T, Lai ST, Lai CL. SARS-associated viral hepatitis caused by a novel coronavirus: report of three cases. Hepatology. 2004 Feb;39(2):302-10.

9829.   Chen Y, Sze J, He ML. HBV cccDNA in patients' sera as an indicator for HBV reactivation and an early signal of liver damage. World J Gastroenterol. 2004 Jan;10(1):82-5.

9830.   Dai CY, YuML, Chen SC, Lin ZY, Hsieh MY, Wang LY, Tsai JF, Chuang WL, Chang WY. Clinical evaluation of the COBAS Amplicor HBV monitor test for measuring serum HBV DNA and comparison with the Quantiplex branched DNA signal amplification assay in Taiwan. J Clin Pathol. 2004 Feb;57(2):141-5.

9831.   Ferenci P. Predicting the therapeutic response in patients with chronic hepatitis C: the role of viral kinetic studies. J Antimicrob Chemother. 2004 Jan;53(1):15-8. Epub 2003 Nov 25. Review. 

9832.   Friedman LS. Controversies in liver biopsy: who, where, when, how, why? Curr Gastroenterol Rep. 2004 Feb;6(1):30-6. Review.

9833.   Ganem D, Prince AM. Hepatitis B virus infection--natural history and clinical consequences. N Engl J Med. 2004 Mar 11;350(11):1118-29. Review.

9834.   Grassi A, Susca M, Ferri S, Gabusi E, D'Errico A, Farina G, Maccariello S, Zauli D, Bianchi FB, Ballardini G. Detection of the M30 neoepitope as a new tool to quantify liver apoptosis: timing and patterns of positivity on frozen and paraffin-embedded sections. Am J Clin Pathol. 2004 Feb;121(2):211-9. 

9835.   Ismail N, Fish GE, Smith MB. Laboratory evaluation of a fully automated chemiluminescence immunoassay for rapid detection of HBsAg, antibodies to HBsAg, and antibodies to hepatitis C virus. J Clin Microbiol. 2004 Feb;42(2):610-7. 

9836.   Kiely P, Kay D, Parker S, Piscitelli L. The significance of third-generation HCV RIBA-indeterminate, RNA-negative results in voluntary blood donors screened with sequential third-generation immunoassays. Transfusion. 2004 Mar;44(3):349-58.

9837.   Lerat H, Hollinger FB. Hepatitis C virus (HCV) occult infection or occult HCV RNA detection? J Infect Dis. 2004 Jan 1;189(1):3-6. Epub 2003 Dec 31. Review.

9838.   Lin KW, Kirchner JT. Hepatitis B. Am Fam Physician. 2004 Jan 1;69(1):75-82. Review. 

9839.   Rajesh K, Bhoi S, Manish K, Sharma B, Singh BM, Gupta BB. Guillain-Barre syndrome and acute hepatitis E: a rare association. J Indian Acad Clin Med 2002; 3(4): 389-91.

9840.   Raker CA, Tabor E, Okayama A, Yu MY, Kohara M, Mueller NE, Tsubouchi H, Stuver SO. HCV core antigen as an alternative to NAT to detect HCV viremia. Transfusion. 2004 Feb;44(2):307-8.

9841.   Ratziu V, Trabut JB, Poynard T. Fat, diabetes, and liver injury in chronic hepatitis C. Curr Gastroenterol Rep. 2004 Feb;6(1):22-9. Review. 

9842.   Rocholl C, Gerber K, Daly J, Pavia AT, Byington CL. Adenoviral infections in children: the impact of rapid diagnosis. Pediatrics. 2004 Jan;113(1 Pt 1):e51-6. 

9843.   Ryder SD, Irving WL, Jones DA, Neal KR, Underwood JC; Trent Hepatitis C Study Group. Progression of hepatic fibrosis in patients with hepatitis C: a prospective repeat liver biopsy study. Gut. 2004 Mar;53(3):451-5.

9844.   Sansonno D, Lauletta G, Dammacco F. Detection and quantitation of HCV core protein in single hepatocytes by means of laser capture microdissection and enzyme-linked immunosorbent assay. J Viral Hepat. 2004 Jan;11(1):27-32. 

9845.   Talal AH, Shata MT, Markatou M, Dorante G, Chadburn A, Koch R, Neumann AU, Ribeiro RM, Perelson AS. Virus dynamics and immune responses during treatment in patients coinfected with hepatitis C and HIV. J Acquir Immune Defic Syndr. 2004 Feb 1;35(2):103-13. 

9846.   van der Eijk AA, Niesters HG, Gotz HM, Janssen HL, Schalm SW, Osterhaus AD, de Man RA. Paired measurements of quantitative hepatitis B virus DNA in saliva and serum of chronic hepatitis B patients: implications for saliva as infectious agent. J Clin Virol. 2004 Feb;29(2):92-4.

9847.   Verucchi G, Calza L, Manfredi R, Chiodo F. Human immunodeficiency virus and hepatitis C virus coinfection: epidemiology, natural history, therapeutic options and clinical management. Infection. 2004 Feb;32(1):33-46. Review. 

9848.   Ward RP, Kugelmas M, Libsch KD. Management of hepatitis C: evaluating suitability for drug therapy. Am Fam Physician. 2004 Mar 15;69(6):1429-36. Review. 

9849.   Yao JD, Beld MG, Oon LL, Sherlock CH, Germer J, Menting S, Se Thoe SY, Merrick L, Ziermann R, Surtihadi J, Hnatyszyn HJ. Multicenter evaluation of the VERSANT hepatitis B virus DNA 3.0 assay. J Clin Microbiol. 2004 Feb;42(2):800-6. 

9850.   Zafrani ES. Non-alcoholic fatty liver disease: an emerging pathological spectrum. Virchows Arch. 2004 Jan;444(1):3-12. 


9851.   Bataller R, Paik YH, Lindquist JN, Lemasters JJ, Brenner DA. Hepatitis C virus core and nonstructural proteins induce fibrogenic effects in hepatic stellate cells.  Gastroenterology. 2004 Feb;126(2):529-40.

9852.   Brenner DA. Gastrointestinal basic science 2002-2003: the year in review. Clin Gastroenterol Hepatol. 2004 Jan;2(1):9-13. Review.

9853.   Chen HL, Chang CJ, Kong MS, Huang FC, Lee HC, Lin CC, Liu CC, Lee IH, Wu TC, Wu SF, Ni YH, Hsu HY, Chen DS, Chang MH. Pediatric fulminant hepatic failure in endemic areas of hepatitis B infection: 15 years after universal hepatitis B vaccination. Hepatology. 2004 Jan;39(1):58-63.

9854.   Ciancio A, Smedile A, Rizzetto M, Lagget M, Gerin J, Korba B. Identification of HBV DNA sequences that are predictive of response to lamivudine therapy. Hepatology. 2004 Jan;39(1):64-73.

9855.   Collantes RS, Younossi ZM. How great is the risk of transmitting the hepatitis C virus sexually? Cleve Clin J Med. 2004 Feb;71(2):160-1.

9856.   D'Abramo CM, Cellai L, Gotte M. Excision of incorporated nucleotide analogue chain-terminators can diminish their inhibitory effects on viral RNA-dependent RNA polymerases. J Mol Biol. 2004 Mar 12;337(1):1-14.

9857.   Daiba A, Inaba N, Ando S, Kajiyama N, Yatsuhashi H, Terasaki H, Ito A, Ogasawara M, Abe A, Yoshioka J, Hayashida K, Kaneko S, Kohara M, Ito S. A low-density cDNA microarray with a unique reference RNA: pattern recognition analysis for IFN efficacy prediction to HCV as a model. Biochem Biophys Res Commun. 2004 Mar 19;315(4):1088-96.

9858.   Fiore AE. Hepatitis A transmitted by food. Clin Infect Dis. 2004 Mar 1;38(5):705-15.

9859.   Francavilla V, Accapezzato D, De Salvo M, Rawson P, Cosimi O, Lipp M, Cerino A, Cividini A, Mondelli MU, Barnaba V. Subversion of effector CD8+ T cell differentiation in acute hepatitis C virus infection: exploring the immunological mechanisms. Eur J Immunol. 2004 Feb;34(2):427-37.

9860.   Goyal A, Kazim SN, Sakhuja P, Malhotra V, Arora N, Sarin SK. Association of TNF-beta polymorphism with disease severity among patients infected with hepatitis C virus. J Med Virol. 2004 Jan;72(1):60-5. Erratum in: J Med Virol. 2004 Mar;72(3):509.

9861.   Gremion C, Grabscheid B, Wolk B, Moradpour D, Reichen J, Pichler W, Cerny A. Cytotoxic T lymphocytes derived from patients with chronic hepatitis C virus infection kill bystander cells via Fas-FasL interaction. J Virol. 2004 Feb;78(4):2152-7.

9862.   Hauri AM, Armstrong GL, Hutin YJ. The global burden of disease attributable to contaminated injections given in health care settings. Int J STD AIDS. 2004 Jan;15(1):7-16.

9863.   Hsu SC, Wu JC, Sheen IJ, Syu WJ. Interaction and replication activation of genotype I and II hepatitis delta antigens. J Virol. 2004 Mar;78(6):2693-700.

9864.   Lopez-Vazquez A, Rodrigo L, Mina-Blanco A, Martinez-Borra J, Fuentes D, Rodriguez M, Perez R, Gonzalez S, Lopez-Larrea C. Extended human leukocyte antigen haplotype EH18.1 influences progression to hepatocellular carcinoma in patients with hepatitis C virus infection. J Infect Dis. 2004 Mar 15;189(6):957-63.

9865.   Mu JJ, Tsay YG, Juan LJ, Fu TF, Huang WH, Chen DS, Chen PJ. The small delta antigen of hepatitis delta virus is an acetylated protein and acetylation of lysine 72 may influence its cellular localization and viral RNA synthesis. Virology. 2004 Feb 5;319(1):60-70.

9866.   Murakami Y, Minami M, Daimon Y, Okanoue T. Hepatitis B virus DNA in liver, serum, and peripheral blood mononuclear cells after the clearance of serum hepatitis B virus surface antigen. J Med Virol. 2004 Feb;72(2):203-14.

9867.   Naganuma A, Dansako H, Nakamura T, Nozaki A, Kato N.  Promotion of microsatellite instability by hepatitis C virus core protein in human non-neoplastic hepatocyte cells. Cancer Res. 2004 Feb 15;64(4):1307-14.

9868.   Nagao Y, Tanaka K, Kobayashi K, Kumashiro R, Sata M. A cohort study of chronic liver disease in an HCV hyperendemic area of Japan: a prospective analysis for 12 years. Int J Mol Med. 2004 Feb;13(2):257-65.

9869.   Op De Beeck A, Voisset C, Bartosch B, Ciczora Y, Cocquerel L, Keck Z, Foung S, Cosset FL, Dubuisson J. Characterization of functional hepatitis C virus envelope glycoproteins. J Virol. 2004 Mar;78(6):2994-3002.

9870.   Pan J, Clayton M, Feitelson MA. Hepatitis B virus X antigen promotes transforming growth factor-beta1 (TGF-beta1) activity by up-regulation of TGF-beta1 and down-regulation of alpha2-macroglobulin. J Gen Virol. 2004 Feb;85(Pt 2):275-82.

9871.   Pollicino T, Squadrito G, Cerenzia G, Cacciola I, Raffa G, Crax A, Farinati F, Missale G, Smedile A, Tiribelli C, Villa E, Raimondo G. Hepatitis B virus maintains its pro-oncogenic properties in the case of occult HBV infection. Gastroenterology. 2004 Jan;126(1):102-10.

9872.   Romero-Gomez M, Montes-Cano MA, Otero-Fernandez MA, Torres B, Sanchez-Munoz D, Aguilar F, Barroso N, Gomez-Izquierdo L, Castellano-Megias VM, Nunez-Roldan A, Aguilar-Reina J, Gonzalez-Escribano MF. SLC11A1 promoter gene polymorphisms and fibrosis progression in chronic hepatitis C. Gut. 2004 Mar;53(3):446-50.

9873.   Scholle F, Li K, Bodola F, Ikeda M, Luxon BA, Lemon SM. Virus-host cell interactions during hepatitis C virus RNA replication: impact of polyprotein expression on the cellular transcriptome and cell cycle association with viral RNA synthesis. J Virol. 2004 Feb;78(3):1513-24.

9874.   Schwartz J, Harrison E, Anderson M, Byrne T, Vargas HE, Douglas DD, Rakela J. Hepatic steatosis in hepatitis C virus genotype 3 infection: does it correlate with body mass index, fibrosis, and HCV risk factors? Dig Dis Sci. 2004 Jan;49(1):25-9.

9875.   Siavoshian S, Abraham JD, Kieny MP, Schuster C. HCV core, NS3, NS5A and NS5B proteins modulate cell proliferation independently from p53 expression in hepatocarcinoma cell lines. Arch Virol. 2004 Feb;149(2):323-36.

9876.   Tanaka T, Inoue K, Hayashi Y, Abe A, Tsukiyama-Kohara K, Nuriya H, Aoki Y, Kawaguchi R, Kubota K, Yoshiba M, Koike M, Tanaka S, Kohara M. Virological significance of low-level hepatitis B virus infection in patients with hepatitis C virus associated liver disease. J Med Virol. 2004 Feb;72(2):223-9.

9877.   Thelu MA, Drouet E, Hilleret MN, Zarski JP. Lack of clinical significance of variability in the internal ribosome entry site of hepatitis C virus. J Med Virol. 2004 Mar;72(3):396-405.

9878.   Weinman SA, Belalcazar LM. Hepatitis C: a metabolic liver disease. Gastroenterology. 2004 Mar;126(3):917-9. Review.

9879.   Wheeler JM, Mortensen NJ. Patient to surgeon infections--fact or fiction (Br J Surg 2003; 90: 1315-1316). Br J Surg. 2004 Feb;91(2):253.

9880.   You S, Stump DD, Branch AD, Rice CM. A cis-acting replication element in the sequence encoding the NS5B RNA-dependent RNA polymerase is required for hepatitis C virus RNA replication. J Virol. 2004 Feb;78(3):1352-66.

9881.   Zhang SL, Yue YF, Bai GQ, Shi L, Jiang H. Mechanism of intrauterine infection of hepatitis B virus. World J Gastroenterol. 2004 Feb 1;10(3):437-8.


9882.   De Schryver A, De Gendt K, Francois G, Van Damme P, Meheus A. Hepatitis B surface antigenaemia following vaccination with a combined vaccine against hepatitis A and B. J Viral Hepat. 2004 Jan;11(1):88-90.

9883.   Puliyel JM. Plea to restore public funding for vaccine development. Lancet. 2004 Feb 21;363(9409):659.

9884.   Torresi J, Bharadwaj M, Jackson DC, Gowans EJ. Neutralising antibody, CTL and dendritic cell responses to hepatitis C virus: a preventative vaccine strategy. Curr Drug Targets. 2004 Jan;5(1):41-56. Review.

9885. Wang RX, Guo Y, Yang CH, Song Y, Chen J, Pang FS, Lei SP, Jia XM, Wen JY, Shi CY. Can HB vaccine yield a booster effect on individuals with positive serum anti-HBs and anti-HBc markers? World J Gastroenterol. 2004 Jan 15;10(2):306-8.


9886.   Andreone P, Gramenzi A, Cursaro C, Felline F, Loggi E, D'Errico A, Spinosa M, Lorenzini S, Biselli M, Bernardi M. Thymosin-alpha 1 plus interferon-alpha for naive patients with chronic hepatitis C: results of a randomized controlled pilot trial. J Viral Hepat. 2004 Jan;11(1):69-73.

9887.   Angelico M, Cepparulo M, Angelico F, Francioso S, Barlattani A, Di Candilo F, Della Vecchia R, Demelia L, De Sanctis G, Gentile S, Grieco A, Parruti G, Sabusco G, Tarquini L, Tosti A, Zaru S; THE SMIEC 1 GROUP.  A randomized controlled trial of amantadine plus interferon-alpha2a vs. interferon-alpha2a alone in naive patients with chronic hepatitis C randomised according to the early virological response to interferon-alpha2a monotherapy. Aliment Pharmacol Ther. 2004 Feb 1;19(3):339-47. 

9888.   Dev A, Patel K, McHutchison JG. New therapies for chronic hepatitis C virus infection. Curr Gastroenterol Rep. 2004 Feb;6(1):77-86. Review. 

9889.   Guardiola P. Effect of HAART on liver-related mortality in patients with HIV/HCV coinfection. Lancet. 2004 Feb 14;363(9408):570; author reply 571.

9890.   Khokhar N. Treatment of interferon non-responsive chronic hepatitis C with triple therapy with interferon, ribavirin, and amantidine can be encouraging. Gut. 2004 Mar;53(3):468-9.

9891.   Klebl BM. Stacking up the armory against viruses. Drug Discov Today. 2004 Feb 15;9(4):162-4.

9892.   Raney AK, Hamatake RK, Hong Z. HEP DART 2003: Frontiers in drug development for viral hepatitis. Expert Opin Investig Drugs. 2004 Mar;13(3):289-93. 

9893.   Russo MW, Fried MW. Guidelines for stopping therapy in chronic hepatitis C. Curr Gastroenterol Rep. 2004 Feb;6(1):17-21. Review.

9894.   Thio CL. Management of chronic hepatitis B in the HIV-infected patient. AIDS Read. 2004 Mar;14(3):122-9, 133, 136-7. Review.

9895. Zollner B, Petersen J, Puchhammer-Stockl E, Kletzmayr J, Sterneck M, Fischer L, Schroter M, Laufs R, Feucht HH. Viral features of lamivudine resistant hepatitis B genotypes A and D. Hepatology. 2004 Jan;39(1):42-50.



Diagnosis, Diagnostics, Immunodiagnosis & Immunodiagnostics:

10475.  Ahmed A, Keeffe EB. Chronic hepatitis C with normal aminotransferase levels. Gastroenterology. 2004 May;126(5):1409-15.

10476.  Aliyu SH, Aliyu MH, Salihu HM, Parmar S, Jalal H, Curran MD. Rapid detection and quantitation of hepatitis B virus DNA by real-time PCR using a new fluorescent (FRET) detection system. J Clin Virol. 2004 Jun;30(2):191-5.

10477.  Berg T, Sarrazin C, Hinrichsen H, Buggisch P, Gerlach T, Zachoval R, Zeuzem S. Does noninvasive staging of fibrosis challenge liver biopsy as a gold standard in chronic hepatitis C? Hepatology. 2004 May;39(5):1456-7; author reply 1457-8.

10478.  Bhattacharya S, Badrinath S, Hamide A, Sujatha S. Co-infection with hepatitis C virus and human immunodeficiency virus among patients with sexually transmitted diseases in Pondicherry, South India. Indian J Path Microbiol 2003; 46(3): 495-7.

10479.  Bjorkman P, Flamholc L, Naucler A, Molnegren V, Wallmark E, Widell A.  GB virus C during the natural course of HIV-1 infection: viremia at diagnosis does not predict mortality. AIDS. 2004 Apr 9;18(6):877-86.

10480.  Brau N, Rodriguez-Torres M, Prokupek D, Bonacini M, Giffen CA, Smith JJ, Frost KR, Kostman JR. Treatment of chronic hepatitis C in HIV/HCV-coinfection with interferon alpha-2b+ full-course vs. 16-week delayed ribavirin. Hepatology. 2004 Apr;39(4):989-98.

10481.  Brunt EM, Di Bisceglie AM. Histological changes after the use of mycophenolate mofetil in autoimmune hepatitis. Hum Pathol. 2004 Apr;35(4):509-12.

10482.  Chan HL, Leung WK, To KF, Chan PK, Lee N, Wu A, Tam JS, Sung JJ. Retrospective analysis of liver function derangement in severe acute respiratory syndrome. Am J Med. 2004 Apr 15;116(8):566-7.

10483.  de Almeida TM, Leitao RC, Andrade JD, Becak W, Carrilho FJ, Sonohara S. Detection of micronuclei formation and nuclear anomalies in regenerative nodules of human cirrhotic livers and relationship to hepatocellular carcinoma. Cancer Genet Cytogenet. 2004 Apr 1;150(1):16-21.

10484.  D'Souza R, Foster GR. Diagnosis and treatment of hepatitis C. J R Soc Med. 2004 May;97(5):223-5. Review.

10485.  el-Shorbagy E, Afefy AF, Ibrahem IA, Mangoud AM, Eissa MH, Sabee EI, Mahrous S, Abdel-Monem A, Ismail A, Morsy TA, Etewa S, Nor Edin E, Mostafa Y, Abouel-Magd Y, el-Sedawy M, Ragab H, el-Tokhy H, Hassan MI, Lakouz K, Abdel-Aziz K, el-Hady G, Saber M.   Non-invasive markers and predictors of severity of hepatic fibrosis in HCV patients at Sharkia Governorate, Egypt. J Egypt Soc Parasitol. 2004 Apr;34(1 Suppl):459-78.

10486.  Hu KQ, Kyulo NL, Lim N, Elhazin B, Hillebrand DJ, Bock T. Clinical significance of elevated alpha-fetoprotein (AFP) in patients with chronic hepatitis C, but not hepatocellular carcinoma. Am J Gastroenterol. 2004 May;99(5):860-5.

10487.  Hutchinson SJ, Goldberg DJ, King M, Cameron SO, Shaw LE, Brown A, MacKenzie J, Wilson K, MacDonald L. Hepatitis C virus among childbearing women in Scotland: prevalence, deprivation, and diagnosis. Gut. 2004 Apr;53(4):593-8.

10488.  Khan N, Aswad S, Shidban H, Aghajani M, Mendez R, Mendez R, Comanor L. Improved detection of HCV Infection in hemodialysis patients using a new HCV RNA qualitative assay: experience of a transplant center. J Clin Virol. 2004 Jun;30(2):175-82.

10489.  Mangoud AM, Eissa MH, Sabee EI, Ibrahem IA, Ismail A, Morsy TA, Nor Edin E, Mostafa Y, Abuel-Magd Y, Afefy AF, el-Shorbagy E, el-Sadawy M, Ragab H, Mahrous S, Abdel Menem A, Etewa S, Hassan MI, Lakouz K, Abdel-Aziz K, Saber M, el-Hady G.  New concept in histopathological grading and staging of chronic hepatitis C infection at Sharkia Governorate, Egypt. J Egypt Soc Parasitol. 2004 Apr;34(1 Suppl):385-400.

10490.  Mittal SK, Agarwal H. Chronic hepatitis B: diagnosis and management. Paediat Today 2004; 7(2): 63-71.

10491.  Pherwani AV. Transcutaneous immunization with hepatitis A vaccine. Paediat Today 2004; 7(1): 42-4.

10492.  Srinivasan R, Hadzic N, Fischer J, Knisely AS. Steatohepatitis and unsuspected micronodular cirrhosis in Dorfman-Chanarin syndrome with documented ABHD5 mutation. J Pediatr. 2004 May;144(5):662-5.

10493.  Strader DB, Wright T, Thomas DL, Seeff LB; American Association for the Study of Liver Diseases. Diagnosis, management, and treatment of hepatitis C. Hepatology. 2004 Apr;39(4):1147-71.

10494.  Sud A, Hui JM, Farrell GC, Bandara P, Kench JG, Fung C, Lin R, Samarasinghe D, Liddle C, McCaughan GW, George J. Improved prediction of fibrosis in chronic hepatitis C using measures of insulin resistance in a probability index. Hepatology. 2004 May;39(5):1239-47.

10495.  Wyatt J, Baker H, Prasad P, Gong YY, Millson C. Steatosis and fibrosis in patients with chronic hepatitis C. J Clin Pathol. 2004 Apr;57(4):402-6.

10496.  Yamashiro T, Nagayama K, Enomoto N, Watanabe H, Miyagi T, Nakasone H, Sakugawa H, Watanabe M. Quantitation of the level of hepatitis delta virus RNA in serum, by real-time polymerase chain reaction--and its possible correlation with the clinical stage of liver disease.J Infect Dis. 2004 Apr 1;189(7):1151-7.


10497.  Adeyemi OM, Jensen D, Attar B, Ghaoui R, Gallagher M, Wolen D, Cotler SJ. Hepatitis C treatment eligibility in an urban population with and without HIV coinfection. AIDS Patient Care STDS. 2004 Apr;18(4):239-45.

10498.  Ahmad K, Janjua NZ, Bin Hamza H, Khan MI. Novel means of spread of bloodborne infections in Pakistan. Lancet. 2004 Jun 12;363(9425):2002.

10499.  Benvegnu L, Gios M, Boccato S, Alberti A. Natural history of compensated viral cirrhosis: a prospective study on the incidence and hierarchy of major complications. Gut. 2004 May;53(5):744-9.

10500.  Bhattacharyya S, Mapa K, Prabhavathi S, Sudhamani SR, Menon PK, John KP, Shivaram C, Amarnath S, Das S. Phylogenetic conservation of the stem-loop III structure of the 5' untranslated region of Hepatitis C virus RNA among natural variants in samples collected from Southern India. Arch Virol. 2004 May;149(5):1015-26.

10501.  Candotti D, Temple J, Owusu-Ofori S, Allain JP. Multiplex real-time quantitative RT-PCR assay for hepatitis B virus, hepatitis C virus, and human immunodeficiency virus type 1. J Virol Methods. 2004 Jun 1;118(1):39-47.

10502.  Chitturi S, Farrell GC, George J. Non-alcoholic steatohepatitis in the Asia-Pacific region: future shock? J Gastroenterol Hepatol. 2004 Apr;19(4):368-74. Review.

10503.  Cooper C, Kilby D. Clinical significance of hepatitis B core antibody positivity in HCV-infected and HCV/HIV coinfected individuals. Clin Infect Dis. 2004 May 1;38(9):1335-7.

10504.  Das K, Kar P, Gupta RK, Das BC. Role of transfusion-transmitted virus in acute viral hepatitis and fulminant hepatic failure of unknown etiology. J Gastroenterol Hepatol. 2004 Apr;19(4):406-12.

10505.  Donaldson PT. Genetics of liver disease: immunogenetics and disease pathogenesis. Gut. 2004 Apr;53(4):599-608. Review.

10506.  Emerson SU, Nguyen H, Graff J, Stephany DA, Brockington A, Purcell RH. In vitro replication of hepatitis E virus (HEV) genomes and of an HEV replicon expressing green fluorescent protein. J Virol. 2004 May;78(9):4838-46.

10507.  Forbes SJ, Russo FP, Rey V, Burra P, Rugge M, Wright NA, Alison MR. A significant proportion of myofibroblasts are of bone marrow origin in human liver fibrosis. Gastroenterology. 2004 Apr;126(4):955-63.

10508.  Fournillier A, Freida D, Defrance T, Merle P, Trepo C, Inchauspe G. Analysis of B-lymphocyte differentiation in patients infected with hepatitis C virus. J Med Virol. 2004 Apr;72(4):566-74.

10509.  Hakamada T, Funatsuki K, Morita H, Ugajin T, Nakamura I, Ishiko H, Matsuzaki Y, Tanaka N, Imawari M. Identification of novel hepatitis C virus-specific cytotoxic T lymphocyte epitopes by ELISpot assay using peptides with human leukocyte antigen-A*2402-binding motifs. J Gen Virol. 2004 Jun;85(Pt 6):1521-31.

10510.  Helbig KJ, Ruszkiewicz A, Semendric L, Harley HA, McColl SR, Beard MR. Expression of the CXCR3 ligand I-TAC by hepatocytes in chronic hepatitis C and its correlation with hepatic inflammation. Hepatology. 2004 May;39(5):1220-9.

10511.  Huy TT, Abe K. Molecular epidemiology of hepatitis B and C virus infections in Asia. Pediatr Int. 2004 Apr;46(2):223-30. Review.

10512.  Jazayeri MS, Dornan ES, Boner W, Fattovich G, Hadziyannis S, Carman WF. Intracellular distribution of hepatitis B virus core protein expressed in vitro depends on the sequence of the isolate and the serologic pattern. J Infect Dis. 2004 May 1;189(9):1634-45.

10513.  Kottilil S, Shin K, Planta M, McLaughlin M, Hallahan CW, Ghany M, Chun TW, Sneller MC, Fauci AS. Expression of chemokine and inhibitory receptors on natural killer cells: effect of immune activation and HIV viremia. J Infect Dis. 2004 Apr 1;189(7):1193-8.

10514.  Kronke J, Kittler R, Buchholz F, Windisch MP, Pietschmann T, Bartenschlager R, Frese M.  Alternative approaches for efficient inhibition of hepatitis C virus RNA replication by small interfering RNAs. J Virol. 2004 Apr;78(7):3436-46.

10515.  Kwun HJ, Jang KL. Natural variants of hepatitis B virus X protein have differential effects on the expression of cyclin-dependent kinase inhibitor p21 gene. Nucleic Acids Res. 2004 Apr 23;32(7):2202-13. Print 2004.

10516.  Laskus T, Radkowski M, Jablonska J, Kibler K, Wilkinson J, Adair D, Rakela J. Human immunodeficiency virus facilitates infection/replication of hepatitis C virus in native human macrophages. Blood. 2004 May 15;103(10):3854-9.

10517.  Liaw YF, Chen YC, Sheen IS, Chien RN, Yeh CT, Chu CM. Impact of acute hepatitis C virus superinfection in patients with chronic hepatitis B virus infection. Gastroenterology. 2004 Apr;126(4):1024-9.

10518.  Liu ZW, Han QY, Zhang N, Kang W. Sequential changes of serum ferritin levels and their clinical significance in lamivudine-treated patients with chronic viral hepatitis B. World J Gastroenterol. 2004 Apr 1;10(7):972-6.

10519.  Lopez-Labrador FX, He XS, Berenguer M, Cheung RC, Wright TL, Greenberg HB. The use of class-I HLA tetramers for the detection of hepatitis C virus NS3-specific CD8(+) T cells in patients with chronic infection. J Immunol Methods. 2004 Apr;287(1-2):91-9.

10520.  Mohammed NA, El-Aleem SA, El-Hafiz HA, McMahon RF. Distribution of constitutive (COX-1) and inducible (COX-2) cyclooxygenase in postviral human liver cirrhosis: a possible role for COX-2 in the pathogenesis of liver cirrhosis. J Clin Pathol. 2004 Apr;57(4):350-4.

10521.  Nielsen SU, Bassendine MF, Burt AD, Bevitt DJ, Toms GL. Characterization of the genome and structural proteins of hepatitis C virus resolved from infected human liver. J Gen Virol. 2004 Jun;85(Pt 6):1497-507.

10522.  Ohishi W, Shirakawa H, Kawakami Y, Kimura S, Kamiyasu M, Tazuma S, Nakanishi T, Chayama K. Identification of rare polymerase variants of hepatitis B virus using a two-stage PCR with peptide nucleic acid clamping. J Med Virol. 2004 Apr;72(4):558-65.

10523.  Orru G, Masia G, Orru G, Romano L, Piras V, Coppola RC. Detection and quantitation of hepatitis E virus in human faeces by real-time quantitative PCR. J Virol Methods. 2004 Jun 15;118(2):77-82.

10524.  Shyamala V, Cottrell J, Arcangel P, Madriaga D, Phelps B, Chien D.  Detection and quantitation of HBV DNA in the WHO International Standard for HIV-1 RNA (NIBSC code: 97/656). J Virol Methods. 2004 Jun 1;118(1):69-72.

10525.  Singh B, Verma M, Verma K. Markers for transfusion-associated hepatitis in north Indian blood donors: prevalence and trends. Jpn J Infect Dis. 2004 Apr;57(2):49-51.

10526.  Singh M, Dicaire A, Wakil AE, Luscombe C, Sacks SL. Quantitation of hepatitis B virus (HBV) covalently closed circular DNA (cccDNA) in the liver of HBV-infected patients by LightCycler real-time PCR. J Virol Methods. 2004 Jun 15;118(2):159-67.

10527.  Tanaka Y, Kanai F, Kawakami T, Tateishi K, Ijichi H, Kawabe T, Arakawa Y, Kawakami T, Nishimura T, Shirakata Y, Koike K, Omata M. Interaction of the hepatitis B virus X protein (HBx) with heat shock protein 60 enhances HBx-mediated apoptosis. Biochem Biophys Res Commun. 2004 May 28;318(2):461-9.

10528.  Thio CL, Netski DM, Myung J, Seaberg EC, Thomas DL. Changes in hepatitis B virus DNA levels with acute HIV infection. Clin Infect Dis. 2004 Apr 1;38(7):1024-9.

10529.  Vivekanandan P, Abraham P, Sridharan G, Chandy G, Daniel D, Raghuraman S, Daniel HD, Subramaniam T. Distribution of hepatitis B virus genotypes in blood donors and chronically infected patients in a tertiary care hospital in southern India. Clin Infect Dis. 2004 May 1;38(9):e81-6.

10530.  Wald O, Pappo O, Safadi R, Dagan-Berger M, Beider K, Wald H, Franitza S, Weiss I, Avniel S, Boaz P, Hanna J, Zamir G, Eid A, Mandelboim O, Spengler U, Galun E, Peled A. Involvement of the CXCL12/CXCR4 pathway in the advanced liver disease that is associated with hepatitis C virus or hepatitis B virus. Eur J Immunol. 2004 Apr;34(4):1164-74.


10531.  Rosenthal P.  Hepatitis A vaccine. N Engl J Med. 2004 May 20;350(21):2211-2; author reply 2211-2.


10532.  Choi JR, Cho DG, Roh KY, Hwang JT, Ahn S, Jang HS, Cho WY, Kim KW, Cho YG, Kim J, Kim YZ. A novel class of phosphonate nucleosides. 9-[(1-phosphonomethoxycyclopropyl)methyl]guanine as a potent and selective anti-HBV agent. J Med Chem. 2004 May 20;47(11):2864-9.

10533.  Coverdale SA, Khan MH, Byth K, Lin R, Weltman M, George J, Samarasinghe D, Liddle C, Kench JG, Crewe E, Farrell GC. Effects of interferon treatment response on liver complications of chronic hepatitis C: 9-year follow-up study. Am J Gastroenterol. 2004 Apr;99(4):636-44. Review.

10534.  De Clercq E. Antiviral drugs in current clinical use. J Clin Virol. 2004 Jun;30(2):115-33. Review.

10535.  Jaeckel E, Wedemeyer H, Wiegand J, Manns MP. Acute hepatitis C virus infection: to treat or not to treat? Gastroenterology. 2004 Apr;126(4):1219-20.

10536.  Mehta SR; Prabhu HRA; Swamy AJ; Dhaliwal H; Prasad D. Delirium tremens. Medical Journal Armed Forces India. 2004 Jan; 60(1): 25-7.

10537.  Stephenson P. Hepatitis C carriers must be found and treated to avert crisis. BMJ. 2004 May 1;328(7447):1031.

10538.  Wedemeyer H, Jackel E, Wiegand J, Cornberg M, Manns MP. Whom? When? How? Another piece of evidence for early treatment of acute hepatitis C. Hepatology. 2004 May;39(5):1201-3.

10539.  Zaidi AK, Awasthi S, deSilva HJ.   Burden of infectious diseases in South Asia. BMJ. 2004 Apr 3;328(7443):811-5. Review.