Complementary Systems of Medicine

(Acupressure, Acupuncture, Alternative Medicine, Aroma therapy, Ayurveda, Complementary Medicine, Herbal Medicine, Homeopathy, Hypnotherapy, Magnetotherapy, Naturopathy, Pranic Healing, Reflexology, Reiki, Siddha, Traditional Medicine, Unani, Yoga & Meditation)

January 2007

Some Selected abstracts:

1.                  Armstrong T, Cohen MZ, Hess KR, Manning R, Lee EL, Tamayo G, Baumgartner K, Min SJ, Yung A, Gilbert M. Complementary and alternative medicine use and quality of life in patients with primary brain tumors. J Pain Symptom Manage. 2006 Aug;32(2):148-54.

Department of Neuro-Oncology, The University of Texas M. D. Anderson Cancer Center, Houston, Texas, USA. Tsarmstr@mdanderson.org

This study explored the use of complementary and alternative medicine (CAM) approaches and their relationship with demographic and disease characteristics and quality of life (QOL) in the primary brain tumor (PBT) population. One hundred one PBT patients were enrolled in this study. The results showed that 34% of patients reported using CAM. Forty-one percent reported using more than one type of CAM. The average cost of each CAM used per month was 69 dollars, with 20% of patients spending more than 100 dollars per month. The majority (74%) reported that their physicians were unaware of their use of CAM. Data analysis found a higher performance status to be the only factor significantly related to use of CAM therapy (P < 0.005). There was no difference in patient report of QOL between users and nonusers of CAM therapies. The high number of patients who do not report CAM use has potential implications for evaluation of symptoms and response to therapy in this population. This may be especially relevant in those patients with higher functional status participating in clinical trials.

2.                  Baum M, Cassileth BR Daniel R, Ernst E Filshie J Nagel GA Horneber M, Kohn M Lejeune S Maher J Terje R Smith WB. The role of complementary and alternative medicine in the management of early breast cancer: recommendations of the European Society of Mastology (EUSOMA). Eur J Cancer. 2006 Aug;42(12):1711-4.

            Department of Surgery, University College London, The Portland Hospital, Consulting    Rooms, 212-214 Great Portland Street, London W1N 6AH, UK. michael@mbaum.freeserve.co.uk

            Patients diagnosed with breast cancer have many needs that for a start include the expectation of cure. Where cure is unlikely there is always a place for hope and spiritual support. Furthermore whether dealing with the early stages or with the advanced disease patients require symptomatic control that encompasses pain relief, control of nausea and vomiting and psychological distress. To achieve all of these goals there is a need that goes beyond the role of scientific medicine. This position papers describes the guidelines for the use of complimentary and alternative medicine (CAM) developed by a workshop on behalf of the European Society of Mastology (EUSOMA).

3.                  Baum M, Ernst E, Lejeune S, Horneber M. Role of complementary and alternative medicine in the care of patients with breast cancer: report of the European Society of Mastology (EUSOMA) Workshop, Florence, Italy, December 2004. Eur J Cancer. 2006 Aug;42(12):1702-10.

            Department of Surgery, University College London, The Portland Hospital, Great portland Street, London W1N 6AH, UK. michael@mbaum.freeserve.co.uk

            The aim of the European Society of Mastology (EUSOMA) Workshop, Florence, Italy, December 2004, was to produce guidelines on the use of complementary and alternative medicine (CAM) for breast cancer. The widespread use of CAM has to be acknowledged and the reasons for this understood. Deficiencies in the practice of conventional medicine that lead to the adoption of CAM need to be addressed. At the same time, CAM use for breast cancer should be quality controlled, avoiding double standards in evaluation, whilst recognising the problems of CAM research. These guidelines, which appear in an accompanying paper, aim to help oncologists and cancer patients alike.

4.                  Chaya MS, Kurpad AV, Nagendra HR, Nagarathna R. The effect of long term combined yoga practice on the basal metabolic rate of healthy adults. BMC Complement Altern Med. 2006 Aug 31;6:28.

Department of Life Sciences, Swami Vivekananda Yoga Research foundation, No 19, Eknath Bhavan, Gavipuram circle, Bangalore-560019, India. chayapu@hotmail.com

BACKGROUND: Different procedures practiced in yoga have stimulatory or inhibitory effects on the basal metabolic rate when studied acutely. In daily life however, these procedures are usually practiced in combination. The purpose of the present study was to investigate the net change in the basal metabolic rate (BMR) of individuals actively engaging in a combination of yoga practices (asana or yogic postures, meditation and pranayama or breathing exercises) for a minimum period of six months, at a residential yoga education and research center at Bangalore. METHODS: The measured BMR of individuals practicing yoga through a combination of practices was compared with that of control subjects who did not practice yoga but led similar lifestyles. RESULTS: The BMR of the yoga practitioners was significantly lower than that of the non-yoga group, and was lower by about 13 % when adjusted for body weight (P < 0.001). This difference persisted when the groups were stratified by gender; however, the difference in BMR adjusted for body weight was greater in women than men (about 8 and 18% respectively). In addition, the mean BMR of the yoga group was significantly lower than their predicted values, while the mean BMR of non-yoga group was comparable with their predicted values derived from 1985 WHO/FAO/UNU predictive equations. CONCLUSION: This study shows that there is a significantly reduced BMR, probably linked to reduced arousal, with the long term practice of yoga using a combination of stimulatory and inhibitory yogic practices.

5.                  Herman PM, Sherman KJ, Erro JH, Cherkin DC, Milliman B, Adams LA.  A method for describing and evaluating naturopathic whole practice. Altern Ther Health Med. 2006 Jul-Aug;12(4):20-8.

Department of Psychology, University of Arizona, Tucson.

CONTEXT: Even though complementary and alternative medicine (CAM) is generally practiced as distinct systems of medicine, almost all CAM research has focused on single therapies. In order to more adequately evaluate the effectiveness of these medical systems, studies that evaluate the outcome of intact whole systems are needed. One challenge lies in defining the whole medical system (and any medical system it is compared to) in a way that ensures treatment fidelity. OBJECTIVE: This paper presents a proposed method to measure treatment fidelity (treatment criteria) in studies of the naturopathic medical system. DESIGN: Illustrative example of the theory-based development and post-hoc "testing" of treatment criteria against an existing database of actual treatments prescribed by a random sample of naturopathic physicians. MAIN OUTCOME MEASURES: Treatment criteria for 3 conditions--menopausal symptoms, bowel dysfunction, and fatigue/fibromyalgia--and their comparison to actual treatments prescribed. RESULTS: A set of meaningful, measurable treatment criteria based on the naturopathic practice principles were defined that could have generated the majority (82%-93%) of treatment prescriptions given at visits for these conditions. Several of the treatment criteria components are common across the 3 conditions studied, and might be appropriate for all visits to doctors of naturopathy (NDs). Others are specific to each condition. In addition to ensuring model validity, these criteria help identify critical components of care, enable study replication, provide a measure of quality of care, and are one step toward allowing CAM to be studied as it is generally practiced-as distinct systems of medicine. SETTING: Work was performed at Bastyr University and the University of Arizona.

6.                  Huang MI, Nir Y, Chen B, Schnyer R, Manber R. A randomized controlled pilot study of acupuncture for postmenopausal hot flashes: effect on nocturnal hot flashes and sleep quality. Fertil Steril. 2006 Sep;86(3):700-10.

Department of Psychiatry and Behavioral Sciences, Stanford University School of Medicine, Stanford, California, USA.

OBJECTIVE: To assess the effectiveness of acupuncture on postmenopausal nocturnal hot flashes and sleep. DESIGN: Prospective randomized placebo-controlled study. SETTING: Stanford University School of Medicine and private acupuncture offices. INTERVENTION(S): Active or placebo acupuncture was administered for nine sessions over seven weeks. MAIN OUTCOME MEASURE(S): Severity and frequency of nocturnal hot flashes from daily diaries and Pittsburgh Sleep Quality Index (PSQI). PATIENT(S): Twenty-nine postmenopausal women experiencing at least seven moderate to severe hot flashes daily, with E(2) <18 pg/mL and FSH 30.0-110.0 IU/L. RESULT(S): Nocturnal hot-flash severity significantly decreased in the active acupuncture group (28%) compared with the placebo group (6%), P=.017. The frequency of nocturnal hot flashes also decreased in the active group (47%, P=.001), though it was not significantly different from the placebo group (24%, P=.170; effect size = 0.65). Treatment did not differentially influence sleep; however, correlations between improvements in PSQI and reductions in nocturnal hot flash severity and frequency were significant (P<.026). CONCLUSION(S): Acupuncture significantly reduced the severity of nocturnal hot flashes compared with placebo. Given the strength of correlations between improvements in sleep and reductions in nocturnal hot flashes, further exploration is merited.

7.                  Jankun J, Selman SH, Aniola J, Skrzypczak-Jankun E. Nutraceutical inhibitors of urokinase: potential        applications in prostate cancer prevention and treatment. Oncol Rep. 2006 Aug;16(2):341-6.

Urology Research Center, Medical University of Ohio, Department of Urology, Toledo, OH 43614-5807, USA. jjankun@meduohio.edu

Epidemiological studies have shown that the clinical incidence of prostate cancer varies by geographical area. When individuals move from low to high prostate cancer incidence areas, the risk of developing cancer increases to the level observed in the indigenous population. It was hypothesized that this observation is related to diet or more specifically to nutraceuticals present in food, medicinal plants, and herbs. Nutraceuticals can inhibit or downregulate enzymes critical for cancer formation. We tested this hypothesis by searching the 3D database of nutraceuticals and docking them to the 3D structure of urokinase. In addition to nutraceuticals, the data-base contains known uPA inhibitors that served as positive controls. From >1,000 compounds, several potential uPA inhibitors have been selected (antipain, leupeptin, folic acid, rosmarinic acid, lavendustin A, fisetin, myricetin, tolfenamic acid). Some of these were subject to further tests on inhibitory activity and inhibition of sprout formation. We found that compounds selected by computational methods indeed inhibit uPA and sprout formation. However, because the database of nutraceuticals was small, we did not expect to find either many or high affinity/specific inhibitors. Rather, we tested this method as a proof of concept. All the facts described above support the hypothesis that nutrients selected by computerized searches can inhibit unwanted uPA activity and thus reduce angiogenesis. If true, a proper diet rich in uPA-inhibiting nutraceuticals might support the prevention of prostrate cancer and be a supportive tool in prostate cancer treatment.

8.                  Joske DJ, Rao A, Kristjanson L. Critical review of complementary therapies in haemato-oncology. Intern Med J. 2006 Sep;36(9):579-86. Review.

Cancer Support Centre and Department of Haematology, Sir Charles Gairdner Hospital, Perth, Western Australia, Australia. david.joske@health.wa.gov.au

There is evidence of the increasing use of complementary and alternative medicine by Australians diagnosed with cancer. Given the increasing desire of cancer patients to use complementary and alternative medicine, it is important that clinicians have a good understanding of the evidence available in this field. This critical review aims to provide an overview of the current evidence pertaining to a range of complementary therapies that are used in a supportive role in the treatment of cancer patients. Treatment methods considered are acupuncture, music therapy, massage and touch therapies and psychological interventions. The efficacy of these complementary therapies in terms of improvement in symptoms and quality of life is examined. Evidence that relates to an effect on immune function and survival is also investigated.

9.                  Khalsa SB, Cope S. Effects of a yoga lifestyle intervention on performance-related characteristics of musicians: a preliminary study. Med Sci Monit. 2006 Aug;12(8):CR325-31.

Division of Sleep Medicine BI, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, USA. khalsa@hms.harvard.edu

BACKGROUND: Previous research has suggested that yoga and meditation practices are effective in stress management, alleviating anxiety and musculoskeletal problems and improving mood and cognitive and physical performance. Musicians experience a number of challenges in their profession including high levels of stress, performance anxiety and performance-related musculoskeletal conditions. Yoga and meditation techniques are therefore potentially useful practices for professional musicians. MATERIAL/METHODS: Musicians enrolled in a prestigious 2-month summer fellowship program were invited to participate in a regular yoga and meditation program at a yoga center during the course of the program. The 10 participants in the yoga program completed baseline and end-program questionnaires evaluating performance-related musculoskeletal conditions, performance anxiety, mood and flow experience. Fellows not participating in the yoga program were recruited to serve as controls and completed the same assessments (N=8). RESULTS: The yoga participants showed some improvements relative to control subjects on most measures, with the relative improvement in performance anxiety being the greatest. CONCLUSIONS: The results from this preliminary study suggest that yoga and meditation may be beneficial as a routine practice to reduce performance anxiety in musicians.

10.              Kumar D, Bajaj S, Mehrotra R. Knowledge, attitude and practice of complementary and alternative medicines for diabetes. Public Health. 2006 Aug;120(8):705-11.  

Department of Community Medicine, Government Medical College and Hospital, Sector 32-A, Chandigarh, India. dinesh_walia@rediffmail.com

OBJECTIVES: To investigate the current status of knowledge, attitude and practice of patients with diabetes relating to complementary and alternative medicine (CAM) in an Indian community, and to determine perceptions about the use of CAM and factors influencing knowledge and usage. SETTING: Endocrine clinic of Swaroop Rani, Nehru Hospital, Allahabad, India. STUDY DESIGN: Hospital-based cross-sectional study. PARTICIPANTS: Patients with diabetes attending the clinic for the first time. SAMPLE SIZE: A sample of 493 study participants selected by systematic sampling from a population of 6094 patients with diabetes. STUDY VARIABLES: Age, socio-economic status, educational status, religion, family history of disease, knowledge and practice of CAM, reasons for using CAM, method of use and perceived relief. STATISTICAL ANALYSIS: Normal test of proportions, chi(2) test, Kolomogorov-Smirnov test. RESULTS: Awareness of CAM among patients was high (71%). High prevalence of CAM use was found (67.7%) among all participants, and 95% among participants aware of CAM, mostly using 'naturopathy' (97.3% among users). No significant gap (P>0.10) between knowledge and practice in different categories was observed. Desire for quick and additional relief was the most common perceived reason for using CAM (86.8%). Higher levels of education and socio-economic status were significant positive correlates of CAM use. Knowledge of CAM was gained mainly from friends and neighbours. About 30% of users adopted CAM without allopathic treatment earlier. Only 42.2% of users perceived some relief by using CAM. Lowering of blood sugar was the most common perceived relief. CAM, along with diet control and exercise, resulted in maximum degree of satisfaction (61.9%) experienced by users. No relief was experienced by 53.6% of users of 'naturopathy'. CONCLUSIONS AND SUGGESTIONS: Use of CAM in diabetes is highly prevalent despite high levels of disappointment after its use. In this study, we suggest the need for health education relating to CAM and self-care in diabetes. Use of CAM should be explored with patients before clinical decisions are made.

11.              Pilkington K, Kirkwood G, Rampes H, Fisher P, Richardson J. Homeopathy for anxiety and anxiety disorders: a systematic review of the  research. Homeopathy. 2006 Jul;95(3):151-62. Review.

School of Integrated Health, University of Westminster, London, UK. k.pilkington@westminster.ac.uk

OBJECTIVE: To conduct a systematic review of the clinical research evidence on homeopathy in the treatment of anxiety and anxiety disorders. METHODS: A comprehensive search of major biomedical databases: MEDLINE, EMBASE, ClNAHL, PsycINFO, Cochrane Library; and of specialist complementary and alternative medicine (CAM) databases: AMED, CISCOM and Hom-Inform was conducted. Efforts were made to identify unpublished and ongoing research using relevant sources and experts in the field. Relevant research was categorised by study type and appraised according to study design. Clinical commentaries were obtained for studies reporting clinical outcomes. RESULTS: Eight randomised controlled studies were identified. The types of anxiety and anxiety disorders studied were test anxiety, generalised anxiety disorder and anxiety related to medical or physical conditions such as cancer or surgical procedures. Single case reports/studies were the most frequently encountered study type but other study types including uncontrolled trials/case series and surveys were also found. No relevant qualitative research was identified. CONCLUSIONS: A comprehensive search demonstrates that the evidence on the benefit of homeopathy in anxiety and anxiety disorders is limited. A number of studies of homeopathy in such conditions were located but the randomised controlled trials report contradictory results, are underpowered or provide insufficient details of methodology. Several uncontrolled and observational studies reported positive results including high levels of patient satisfaction but because of the lack of a control group, it is difficult to assess the extent to which any response is due to homeopathy. Adverse effects reported appear limited to 'remedy reactions' and included temporary worsening of symptoms and reappearance of old symptoms. On the basis of this review it is not possible to draw firm conclusions on the efficacy or effectiveness of homeopathy for anxiety. However, surveys suggest that homeopathy is quite frequently used by people suffering from anxiety. If shown to be effective, it is possible that homeopathy may have benefits in terms of adverse effects and acceptability to patients. Consequently, further investigation is indicated. Future research should be of pragmatic design and include qualitative studies.

12.              Schneider RH, Walton KG, Salerno JW, Nidich SI. Cardiovascular disease prevention and health promotion with the transcendental meditation program and Maharishi consciousness-based health are. Ethn Dis. 2006 Summer;16(3 Suppl 4):S4-15-26. Review.

Institute for Natural Medicine and Prevention, Maharishi University of Management, Fairfield, Iowa, USA. rschneider@mum.edu

This article summarizes the background, rationale, and clinical research on a traditional system of natural health care that may be useful in the prevention of cardiovascular disease (CVD) and promotion of health. Results recently reported include reductions in blood pressure, psychosocial stress, surrogate markers for atherosclerotic CVD, and mortality. The randomized clinical trials conducted so far have involved applications to both primary and secondary prevention as well as to health promotion more generally. The results support the applicability of this approach for reducing ethnic health disparities associated with environmental and psychosocial stress. Proposed mechanisms for the effects of this traditional system include enhanced resistance to physiological and psychological stress and improvements in homeostatic and self-repair processes. This system may offer clinical and cost effectiveness advantages for health care, particularly in preventive cardiology.

13.              Sterer N, Rubinstein Y. Effect of various natural medicinals on salivary protein putrefaction and malodor production. Quintessence Int. 2006 Sep;37(8):653-8.

Department of Prosthodontics, The Hebrew University, Hadassah School of Dental Medicine, Jerusalem, Israel. sterer@hadassah.org.il

OBJECTIVE: Salivary incubation assays are commonly used in oral malodor studies. Using an in vitro model system, the effect of various natural medicinals (i.e., echinacea, propolis, elder, mastic gum, marigold, sage, lavender, thyme, and chamomile) on salivary protein putrefaction and malodor production was examined. METHOD AND MATERIALS: Malodor production levels were scored by an experienced odor judge. Volatile sulfide levels were measured using a sulfide monitor (Halimeter), and salivary protein degradation was determined densitometrically following electrophoresis on polyacrylamide gel (SDS-PAGE). Microbial population was evaluated by viable counts and microscopy. RESULTS: Whereas all of the various medicinals caused some reduction in malodor production from the incubated whole saliva, echinacea and lavender were the most effective. CONCLUSION: The bioassay utilized in the present study suggests that these herbs may inhibit oral malodor production.

14.              Thomas KJ, MacPherson H, Thorpe L, Brazier J, Fitter M, Campbell MJ, Roman M, Walters SJ, Nicholl J. Randomised controlled trial of a short course of traditional acupuncture compared with usual care for persistent non-specific low back pain. BMJ. 2006 Sep 23;333(7569):623

Objective: To determine whether a short course of traditional acupuncture improves longer term outcomes  

for patients with persistent non-specific low back pain in primary care. Design: Pragmatic, open, randomised controlled trial. Setting: Three private acupuncture clinics and 18 general practices in York, England. Participants: 241 adults aged 18-65 with non-specific low back pain of 4-52 weeks' duration. Interventions: 10 individualised acupuncture treatments from one of six qualified acupuncturists (160 patients) or usual care only (81 patients).  Main outcome measures: The primary outcome was SF-36 bodily pain, measured at 12 and 24 months. Other outcomes included reported use of analgesics, scores on the Oswestry pain disability index, safety, and patient satisfaction. Results: 39 general practitioners referred 289 patients of whom 241 were randomised. At 12 months average SF-36 pain scores increased by 33.2 to 64.0 in the acupuncture group and by 27.9 to 58.3 in the control group. Adjusting for baseline score and for any clustering by acupuncturist, the estimated intervention effect was 5.6 points (95% confidence interval -0.2 to 11.4) at 12 months (n = 213) and 8.0 points (2.8 to 13.2) at 24 months (n = 182). The magnitude of the difference between the groups was about 10%-15% of the final pain score in the control group. Functional disability was not improved. No serious or life threatening events were reported. Conclusions: Weak evidence was found of an effect of acupuncture on persistent non-specific low back pain at 12 months, but stronger evidence of a small benefit at 24 months. Referral to a qualified traditional acupuncturist for a short course of treatment seems safe and acceptable to patients with low back pain.

15.              Woolhouse M. Complementary medicine for pregnancy complications. Aust Fam Physician. 2006 Sep;35(9):695. Review.

michellewoolhouse@hotmail.com

For some women, pregnancy can bring a myriad of distressing symptoms. Nausea affects up to 85% of women during early pregnancy and about half of these women also experience vomiting. For some women, it can be very debilitating. Conventional anti-emetics bring with them a risk of potential teratogenic effects during the critical stage of early pregnancy. Women tend to feel more comfortable taking a natural or herbal substance to help manage these issues.

16.              Yeh GY, Davis RB, Phillips RS. Use of complementary therapies in patients with cardiovascular disease. Am J Cardiol. 2006 Sep 1;98(5):673-80. 

Division for Research and Education in Complementary and Integrative Medical Therapies, Harvard Medical School, Boston, Massachusetts, USA. gyeh@hms.harvard.edu

Previous studies have suggested that patients with chronic medical conditions use complementary and alternative medicine (CAM) at a higher rate than the general population. Despite recent interest in CAM for cardiovascular disease, few data are available regarding patterns of use in patients with cardiovascular disease in the United States. This study used the 2002 National Health Interview Survey and analyzed data on CAM use in 10,572 respondents with cardiovascular disease. Among those with cardiovascular disease, 36% had used CAM (excluding prayer) in the previous 12 months. The most commonly used therapies were herbal products (18%) and mind-body therapies (17%). Among herbs, echinacea, garlic, ginseng, ginkgo biloba, and glucosamine with or without chondroitin were most commonly used. Among mind-body therapies, deep-breathing exercises and meditation were most commonly used. Overall, CAM was used most frequently for musculoskeletal complaints (24% of respondents who used mind-body therapies, 22% who used herbs, 45% who used any CAM). Mind-body therapies were also used for anxiety or depression (23%) and stress or emotional health and wellness (16%). Herbs were commonly used for head and chest colds (22%). Fewer respondents (10%) used CAM specifically for their cardiovascular conditions (5% for hypertension, 2% for coronary disease, 3% for vascular insufficiency, < 1% for heart failure or stroke). Most, however, who used CAM for their cardiovascular condition perceived the therapies to be helpful (80% for herbs, 94% for mind-body therapies). CAM use was more common in younger respondents, women, Asians, and those with more education and greater incomes. In conclusion, CAM use, particularly herbs and mind-body therapies, is common in the United States in patients with cardiovascular disease and mirrors use in the general population. CAM use specifically to treat cardiovascular conditions, however, is less common.

15248.  Acero N, Llinares F, Galan de Mera A, Oltra B, Munoz-Mingarro D. Apoptotic and free radical scavenging properties of the methanolic extract of Gentianella alborosea. itoterapia. 2006 Sep;77(6):475-7.  

15249.  Agnoletto V, Chiaffarino F, Nasta P, Rossi R, Parazzini F. Use of complementary and alternative medicine in HIV-infected subjects. Complement Ther Med. 2006 Sep;14(3):193-9.  

15250.  Ahmed N, Coffey JB, Oh R. Clinical inquiries. What is the best management for patients who have a TIA while on aspirin therapy? J Fam Pract. 2006 Jul;55(7):627-8. Review.

15251.  Anitha G, Josepha Lourdu Raj J, Narasimhan S, Anand Solomon K, Rajan SS.   Nimbolide and isonimbolide. J Asian Nat Prod Res. 2006 Jul-Aug;8(5):445-9.

15252.  Azzazy HM, Mansour MM, Kazmierczak SC. Nanodiagnostics: a new frontier for clinical laboratory medicine. Clin Chem. 2006 Jul;52(7):1238-46.   Review.

15253.  Beal T, Kemper KJ, Gardiner P, Woods C. Long-term impact of four different strategies for delivering an on-line curriculum about herbs and other dietary supplements. BMC Med Educ. 2006 Aug 7;6:39.

15254.  Bellack AS. Scientific and consumer models of recovery in schizophrenia: concordance, contrasts, and implications. Schizophr Bull. 2006 Jul;32(3):432-42.   

15255.  Cohen M. Complementary medicines and weight management. Aust Fam Physician. 2006 Aug;35(8):605-6. Review.

15256.  Ernst E. Integrated medicine: good intentions, poor logic? J R Soc Health. 2006 Sep;126(5):206-7.

15257.  Evanson TA. Addressing domestic violence through maternal-child health home visiting: what we do and do not know. J Community Health Nurs. 2006 Summer;23(2):95-111. Review.

15258.  Fitzpatrick M. Complementary and alternative medicine: why I'm opposed to integration. J R Soc Health. 2006 Sep;126(5):207-8.

15259.  Frei H, von Ammon K, Thurneysen A. Treatment of hyperactive children: increased efficiency through modifications of homeopathic diagnostic procedure. Homeopathy. 2006 Jul;95(3):163-70.

15260.  Goldman E. Cutting costs through prevention. J Med Pract Manage. 2006 Jul-Aug;22(1):41-4.

15261.  Harris RE, Gracely RH, McLean SA, Williams DA, Giesecke T, Petzke F, Sen A, Clauw DJ. Comparison of clinical and evoked pain measures in fibromyalgia. J Pain. 2006 Jul;7(7):521-7.

15262.  Herman CJ, Dente JM, Allen P, Hunt WC.  Ethnic differences in the use of complementary and alternative therapies among adults with osteoarthritis. Prev Chronic Dis. 2006 Jul;3(3):A80.  

15263.  Kennedy S, Jin X, Yu H, Zhong S, Magill P, van Vliet T, Kistemaker C, Voors C, Pasman W. Randomized controlled trial assessing a traditional Chinese medicine remedy in the treatment of primary dysmenorrhea. Fertil Steril. 2006 Sep;86(3):762-4.  

15264.  Kerr C. New consumer guidance on herbal medicines. Lancet Oncol. 2006 Sep;7(9):714.

15265.  Lamas GA, Hussein SJ. EDTA chelation therapy meets evidence-based medicine. Complement Ther Clin Pract. 2006 Aug;12(3):213-5.   Review.

15266.  Letasiova S, Jantova S, Cipak L, Muckova M. Berberine-antiproliferative activity in vitro and induction of apoptosis/necrosis of the U937 and B16 cells. Cancer Lett. 2006 Aug 8;239(2):254-62.  

15267.  Leung WK, Wu JC, Liang SM, Chan LS, Chan FK, Xie H, Fung SS, Hui AJ,  Wong VW, Che CT, Sung JJ.  Treatment of diarrhea-predominant irritable bowel syndrome with traditional Chinese herbal medicine: a randomized placebo-controlled trial. Am J Gastroenterol. 2006 Jul;101(7):1574-80.

15268.  Lowenfels AB. Does gum chewing ameliorate postoperative ileus? J Am Coll Surg. 2006 Sep;203(3):404-5.

15269.  Lu Y, Zhang C, Bucheli P, Wei D. Citrus flavonoids in fruit and traditional Chinese medicinal food ingredients in China. Plant Foods Hum Nutr. 2006 Jun;61(2):57-65.  

15270.  McKay DL, Blumberg JB.  A review of the bioactivity and potential health benefits of peppermint tea (Mentha piperita L.). Phytother Res. 2006 Aug;20(8):619-33. Review.

15271.  Milgrom LR. Is homeopathy possible? J R Soc Health. 2006 Sep;126(5):211-8. Review.

15272.  Moss J, Yuan CS. Herbal medicines and perioperative care.  Anesthesiology. 2006 Sep;105(3):441-2.

15273.  Niggemann B, Gruber C. Does unconventional medicine work through conventional modes of action? J Allergy Clin Immunol. 2006 Sep;118(3):569-73. Review.

15274.  O'Mara A. Complementary and alternative medicine research and cooperative groups: can it happen? J Pediatr Oncol Nurs. 2006 Sep-Oct;23(5):258-60.

15275.  Petit-Zeman S. Better research for better healthcare. J R Soc Med. 2006 Jul;99(7):330-1.

15276.  Post-White J, Hawks R, O'Mara A, Ott MJ.  Future directions of CAM research in pediatric oncology. J Pediatr Oncol Nurs. 2006 Sep-Oct;23(5):265-8. Review.

15277.  Post-White J. Complementary and alternative medicine in pediatric oncology. J Pediatr Oncol Nurs. 2006 Sep-Oct;23(5):244-53. Review.

15278.  Presho M. Earning and learning: recruitment and retention in post registration nurse education. Nurse Educ Today. 2006 Aug;26(6):511-8.  

15279.  Ratcliffe J, Thomas KJ, MacPherson H, Brazier J. A randomised controlled trial of acupuncture care for persistent low back pain: cost effectiveness analysis. BMJ. 2006 Sep 23;333(7569):626.  

15280.  Ribeiro MA, Harrigan RC. The use of Complementary and Alternative Medicine by Asian women of Hawai'i in the treatment of breast cancer. Hawaii Med J. 2006 Jul;65(7):198-205.

15281.  Ribeiro MA, Harrigan RC. A literature review on Complementary and Alternative Medicine for the treatment of breast cancer: Hawai'i. Hawaii Med J. 2006 Jul;65(7):190-7. Review.

15282.  Ricotti V, Delanty N. Use of complementary and alternative medicine in epilepsy. Curr Neurol Neurosci Rep. 2006 Jul;6(4):347-53. Review.

15283.  Shen X, Ding G, Wei J, Zhao L, Zhou Y, Deng H, Lao L. An infrared radiation study of the biophysical characteristics of traditional moxibustion. Complement Ther Med. 2006 Sep;14(3):213-9.  

15284.  Sookkongwaree K, Geitmann M, Roengsumran S, Petsom A, Danielson UH.  Inhibition of viral proteases by Zingiberaceae extracts and flavones isolated from Kaempferia parviflora. Pharmazie. 2006 Aug;61(8):717-21.

15285.  Sun Z, Stevenson G. Transrenal fixation of aortic stent-grafts: short- to midterm effects on renal function--a systematic review. Radiology. 2006 Jul;240(1):65-72.   Review.

15286.  Tapsell LC, Hemphill I, Cobiac L, Patch CS, Sullivan DR, Fenech M, Roodenrys S, Keogh JB, Clifton PM, Williams PG, Fazio VA, Inge KE. Health benefits of herbs and spices: the past, the present, the future. Med J Aust. 2006 Aug 21;185(4 Suppl):S4-24. Review. 

15287.  Torkelson C, Harris I, Kreitzer MJ. Evaluation of a complementary and alternative medicine rotation in medical school. Altern Ther Health Med. 2006 Jul-Aug;12(4):30-4.

15288.  Tseng TH, Lee YJ. Evaluation of natural and synthetic compounds from East Asiatic folk medicinal plants on the mediation of cancer. Anticancer Agents Med Chem. 2006 Jul;6(4):347-65. Review.

15289.  van den Brink-Muinen A, Rijken PM. Does trust in health care influence the use of complementary and alternative medicine by chronically ill people? BMC Public Health. 2006 Jul 18;6:188.

15290.  Vejdani R, Shalmani HR, Mir-Fattahi M, Sajed-Nia F, Abdollahi M, Zali MR, Alizadeh AH, Bahari A, Amin G. The efficacy of an herbal medicine, Carmint, on the relief of abdominal pain and bloating in patients with irritable bowel syndrome: a pilot study. Dig Dis Sci. 2006 Aug;51(8):1501-7.  

15291.  Verhoef MJ, Boon HS, Mutasingwa DR. The scope of naturopathic medicine in Canada: an emerging profession. Soc Sci Med. 2006 Jul;63(2):409-17.    

15292.  White P, Lewith G.  Could neuroimaging help us to interpret the clinical effects of acupuncture? Bundesgesundheitsblatt Gesundheitsforschung Gesundheitsschutz. 2006 Aug;49(8):743-8.

15293.  Won HJ, Han CH, Kim YH, Kwon HJ, Kim BW, Choi JS, Kim KH.   Induction of apoptosis in human acute leukemia Jurkat T cells by Albizzia julibrissin extract is mediated via mitochondria-dependent caspase-3 activation. J Ethnopharmacol. 2006 Jul 19;106(3):383-9.   

15294.  Wu E. Worlds of Western medicine and Chinese medicine learning from each other. J Am Osteopath Assoc. 2006 Jul;106(7):427-8.

15295.  Zhou J, Zhang S, Ong CN, Shen HM. Critical role of pro-apoptotic Bcl-2 family members in andrographolide-induced apoptosis in human cancer cells. Biochem Pharmacol. 2006 Jul 14;72(2):132-44.  

 

Back

 

April 2007

Some Selected Abstracts:

1.                  Anderson JE, Hansen LL, Mooren FC, Post M, Hug H, Zuse A, Los M. Methods and biomarkers for the diagnosis and prognosis of cancer and other diseases: towards personalized medicine. Drug Resist Updat. 2006 Aug-Oct;9(4-5):198-210.

Department of Human Anatomy and Cell Science, University of Manitoba, Winnipeg, Man, Canada.

The rapid development of new diagnostic procedures, the mapping of the human genome, progress in mapping genetic polymorphisms, and recent advances in nucleic acid- and protein chip technologies are driving the development of personalized therapies. This breakthrough in medicine is expected to be achieved largely due to the implementation of "lab-on-the-chip" technology capable of performing hundreds, even thousands of biochemical, cellular and genetic tests on a single sample of blood or other body fluid. Focusing on a few disease-specific examples, this review discusses selected technologies and their combinations likely to be incorporated in the "lab-on-the-chip" and to provide rapid and versatile information about specific diseases entities. Focusing on breast cancer and after an overview of single-nucleotide polymorphism (SNP)-screening methodologies, we discuss the diagnostic and prognostic importance of SNPs. Next, using Duchenne muscular dystrophy (DMD) as an example, we provide a brief overview of powerful and innovative integration of traditional immuno-histochemistry techniques with advanced biophysical methods such as NMR-spectroscopy or Fourier-transformed infrared (FT-IR) spectroscopy. A brief overview of the challenges and opportunities provided by protein and aptamer microarrays follows. We conclude by highlighting novel and promising biochemical markers for the development of personalized treatment of cancer and other diseases: serum cytochrome c, cytokeratin-18 and -19 and their proteolytic fragments for the detection and quantitation of malignant tumor mass, tumor cell turn-over, inflammatory processes during hepatitis and Epstein-Barr virus (EBV)-induced hemophagocytic lymphohistiocytosis and apoptotic/necrotic cancer cell death.

2.                  Arias AJ, Steinberg K, Banga A, Trestman RL.  Systematic review of the efficacy of meditation techniques as treatments for medical illness. J Altern Complement Med. 2006 Oct;12(8):817-32. Review. 

Department of Psychiatry, University of Connecticut Medical School, Farmington, CT, USA. arias@psychiatry.uchc.edu

BACKGROUND: Meditative techniques are sought frequently by patients coping with medical and psychological problems. Because of their increasingly widespread appeal and use, and the potential for use as medical therapies, a concise and thorough review of the current state of scientific knowledge of these practices as medical interventions was conducted. PURPOSE: To systematically review the evidence supporting efficacy and safety of meditative practices in treating illnesses, and examine areas warranting further study. Studies on normal healthy populations are not included. METHODS: Searches were performed using PubMed, PsycInfo, and the Cochrane Database. Keywords were Meditation, Meditative Prayer, Yoga, Relaxation Response. Qualifying studies were reviewed and independently rated based on quality by two reviewers. Mid-to-high-quality studies (those scoring above 0.65 or 65% on a validated research quality scale) were included. RESULTS: From a total of 82 identified studies, 20 randomized controlled trials met our criteria. The studies included 958 subjects total (397 experimentally treated, 561 controls). No serious adverse events were reported in any of the included or excluded clinical trials. Serious adverse events are reported in the medical literature, though rare. The strongest evidence for efficacy was found for epilepsy, symptoms of the premenstrual syndrome and menopausal symptoms. Benefit was also demonstrated for mood and anxiety disorders, autoimmune illness, and emotional disturbance in neoplastic disease. CONCLUSIONS: The results support the safety and potential efficacy of meditative practices for treating certain illnesses, particularly in nonpsychotic mood and anxiety disorders. Clear and reproducible evidence supporting efficacy from large, methodologically sound studies is lacking.

3.                  Baer HA.  The drive for legitimation in Australian naturopathy: successes and dilemmas. Soc Sci Med. 2006 Oct;63(7):1771-83.

University of Melbourne Carlton, Vic., Australia. hbaer@unimelb.edu.au hbaer@unimelb.edu.au

Whereas naturopathic physicians have either "licensure" or state-mandated "registration" in 13 US states and four Canadian provinces, naturopaths in Australia have thus far failed to obtain "statutory registration" in any political jurisdiction, despite the fact that chiropractors and osteopaths have done so in all Australian states and territories, and acupuncturists and Traditional Chinese Medicine practitioners have done so in the state of Victoria. Ironically, naturopathy and various other complementary medical systems are taught in many public tertiary institutions. This essay presents an overview of the development and the current socio-political status of naturopathy in Australia and its redefinition in some contexts as "natural therapies" and "natural medicine" or even as the major component of complementary medicine. It also examines reasons why the Australian state has come to express an interest in naturopathy along with other complementary medical systems.

4.                  Chang EY, Glissmeyer M, Tonnes S, Hudson T, Johnson N.  Outcomes of breast cancer in patients who use alternative therapies as primary treatment. Am J Surg. 2006 Oct;192(4):471-3. 

Legacy Cancer Services, Surgical Associates, 1130 NW 22nd St., Ste 500, Portland, OR 97210, USA.

BACKGROUND: Some breast cancer patients opt for alternative treatments in place of conventional treatments. The lack of published data on the outcome of this strategy may contribute to this trend. METHODS: A chart review was performed of breast cancer patients who refused or delayed standard surgery, chemotherapy, and/or radiation therapy. Prognosis was calculated for recommended and actual therapy. RESULTS: Thirty-three patients were included in the analysis. Of 11 patients who initially refused surgery, 10 developed disease progression. Of 3 patients who refused adequate nodal sampling, 1 developed nodal recurrence. Of 10 patients who refused local control procedures, 2 developed local recurrences and 2 died of metastatic disease. By refusing chemotherapy, 9 patients increased their estimated 10-year mortality rate from 17% to 25%. CONCLUSIONS: Alternative therapies used as primary treatment for breast cancer are associated with increased recurrence and death. Homeopathy instead of surgery resulted in disease progression in most patients. These data may aid patients who are considering alternative therapies.

5.                  Culos-Reed SN, Carlson LE, Daroux LM, Hately-Aldous S.  A pilot study of yoga for breast cancer survivors: physical and psychological benefits. Psychooncology. 2006 Oct;15(10):891-7.

Faculty of Kinesiology, University of Calgary, Calgary, Canada. nculosre@ucalgary.ca

BACKGROUND: Physical activity provides a number of physical and psychological benefits to cancer survivors, including lessening the impact of detrimental cancer-related symptoms and treatment side-effects (e.g. fatigue, nausea), and improving overall well-being and quality of life. The purpose of the present pilot study was to examine the physical and psychological benefits afforded by a 7-week yoga program for cancer survivors. METHOD: Eligible participants (per-screened with PAR-Q/PAR-MED-X) were randomly assigned to either the intervention (n=20) or control group (n=18). All participants completed pre- and post-testing assessments immediately before and after the yoga program, respectively. RESULTS: The yoga program participants (M age=51.18 (10.33); 92% female) included primarily breast cancer survivors, on average 55.95 (54.39) months post-diagnosis. Significant differences between the intervention and the control group at post-intervention were seen only in psychosocial (i.e. global quality of life, emotional function, and diarrhea) variables (all p's <0.05). There were also trends for group differences, in the hypothesized directions, for the psychosocial variables of emotional irritability, gastrointestinal symptoms, cognitive disorganization, mood disturbance, tension, depression, and confusion (all p's <0.10). Finally, there were also significant improvements in both the program participants and the controls from pre- to post-intervention on a number of physical fitness variables. CONCLUSIONS: These initial findings suggest that yoga has significant potential and should be further explored as a beneficial physical activity option for cancer survivors. Future research might attempt to include a broader range of participants (e.g. other types of cancer diagnoses, male subjects), a larger sample size, and a longer program duration in an RCT. 

6.                  Erler F, Ulug I, Yalcinkaya B.  Repellent activity of five essential oils against Culex pipiens. Fitoterapia. 2006 Dec;77(7-8):491-4.

Akdeniz University, Faculty of Agriculture, Plant Protection Department, 07070 Antalya, Turkey. erler@akdeniz.edu.tr

Essential oils extracted from the seeds of anise (Pimpinella anisum), dried fruits of eucalyptus (Eucalyptus camaldulensis), dried foliage of mint (Mentha piperita) and basil (Ocimum basilicum) and fresh foliage of laurel (Laurus nobilis) were tested for their repellency against the adult females of Culex pipiens. All essential oils showed repellency in varying degrees, eucalyptus, basil and anise being the most active.

7.                  Langevin HM, Sherman KJ.  Pathophysiological model for chronic low back pain integrating connective tissue and nervous system mechanisms. Med Hypotheses. 2007;68(1):74-80.

Department of Neurology, Given C423, University of Vermont, Burlington, VT 05405, United States. Helene.langevin@uvm.edu

Although chronic low back pain (cLBP) is increasingly recognized as a complex syndrome with multifactorial etiology, the pathogenic mechanisms leading to the development of chronic pain in this condition remain poorly understood. This article presents a new, testable pathophysiological model integrating connective tissue plasticity mechanisms with several well-developed areas of research on cLBP (pain psychology, postural control, neuroplasticity). We hypothesize that pain-related fear leads to a cycle of decreased movement, connective tissue remodeling, inflammation, nervous system sensitization and further decreased mobility. In addition to providing a new, testable framework for future mechanistic studies of cLBP, the integration of connective tissue and nervous system plasticity into the model will potentially illuminate the mechanisms of a variety of treatments that may reverse these abnormalities by applying mechanical forces to soft tissues (e.g. physical therapy, massage, chiropractic manipulation, acupuncture), by changing specific movement patterns (e.g. movement therapies, yoga) or more generally by increasing activity levels (e.g. recreational exercise). Non-invasive measures of connective tissue remodeling may eventually become important tools to evaluate and follow patients with cLBP in research and clinical practice. An integrative mechanistic model incorporating behavioral and structural aspects of cLBP will strengthen the rationale for a multidisciplinary treatment approach including direct mechanical tissue stimulation, movement reeducation, psychosocial intervention and pharmacological treatment to address this common and debilitating condition.

8.                  Lau MA, Bishop SR, Segal ZV, Buis T, Anderson ND, Carlson L, Shapiro S, Carmody J, Abbey S, Devins G. The Toronto Mindfulness Scale: development and validation. J Clin Psychol. 2006 Dec;62(12):1445-67.

Centre for Addiction and Mental Health and the University of Toronto. mark_lau@camh.net

In this study, the authors both developed and validated a self-report mindfulness measure, the Toronto Mindfulness Scale (TMS). In Study 1, participants were individuals with and without meditation experience. Results showed good internal consistency and two factors, Curiosity and Decentering. Most of the expected relationships with other constructs were as expected. The TMS scores increased with increasing mindfulness meditation experience. In Study 2, criterion and incremental validity of the TMS were investigated on a group of individuals participating in 8-week mindfulness-based stress reduction programs. Results showed that TMS scores increased following treatment, and Decentering scores predicted improvements in clinical outcome. Thus, the TMS is a promising measure of the mindfulness state with good psychometric properties and predictive of treatment outcome. (c) 2006 Wiley Periodicals, Inc.

9.                  Malik VS, Hu FB.  Popular weight-loss diets: from evidence to practice. Nat Clin Pract Cardiovasc Med. 2007 Jan;4(1):34-41. Review.

Department of Nutrition, Harvard School of Public Health, 665 Huntington Avenue, Boston, MA 02115, USA.

The increasing number of overweight and obese individuals has become one of the leading public health concerns in many countries around the world. Concomitant with this increase in the prevalence of obesity has been the rise in the number of weight-loss diets, many of which alter macronutrient composition, but with the majority focused on carbohydrate restriction. Low-carbohydrate diets are attractive because they promise rapid weight loss without having to count calories and compromise the consumption of many palatable foods. By contrast, traditional dietary recommendations for weight loss endorse a fat-restricted and calorie-restricted diet high in complex carbohydrates. Evidence indicates that low-carbohydrate diets could be better in terms of short-term weight loss relative to traditional low-fat diets, but little is known about their long-term utility and safety. Diets based on the traditional Mediterranean dietary pattern are becoming increasingly popular because of their healthful benefits, particularly regarding cardiovascular outcomes. Mediterranean diets encourage consumption of a variety of palatable foods, optimizing adherence and sustainability. In this Review we discuss the current evidence on the efficacy of low-fat, low-carbohydrate and Mediterranean dietary patterns for weight loss, their potential mechanisms of action and important clinical considerations.         

10.               Maurer D, Colt R.  An evidence-based approach to the management of depression. Prim Care. 2006 Dec;33(4):923-41, vii. Review. 

Madigan Army Medical Center, Building 9040, Fitzsimmons Drive, Tacoma, WA 98431, USA. douglas.maurer@us.army.mil

Increasing numbers of patients are using complementary medicine for the treatment of depression, which complicates management. What is the evidence in support of one medication over another? What medications are safe to use in children and pregnant women? Is there any evidence supporting over-the-counter supplements? These are just a few of the questions that primary care physicians face on a daily basis. This article attempts to answer these questions and many others in an evidence-based approach to the management of depression, which focuses on diagnosis, medical management, and complementary treatments

11.              McDonald A, Burjan E, Martin S.  Yoga for patients and carers in a palliative day care setting. Int J Palliat Nurs. 2006 Nov;12(11):519-23. aileenmedusa@googlemail.com

This study suggests that yoga can be of benefit to patients (and carers) in palliative care settings. Complementary therapies have been employed in our day care unit for several years--aromatherapy, reflexology and massage--and have grown in popularity, enabling relaxation and a feeling of well-being. For patients striving to remain physically fit and, in consultation with our physiotherapist, we felt there may be a role for a gentle form of yoga. A study of the literature yielded information on yoga and cancer but little evidence of its use in palliative care. Having identified a form of yoga that could be adapted for those with physical frailties-- Dru yoga--a 12-week pilot project was introduced into the day care unit. This proved to be highly successful and has now been incorporated as part of our therapeutic service.

12.              McLean TW, Kemper KJ.  Lifestyle, biomechanical, and bioenergetic complementary therapies in pediatric oncology. J Soc Integr Oncol. 2006 Fall;4(4):187-93. Review. Department of Pediatrics, Wake Forest University School of Medicine, Winston-Salem, NC 27157, USA. tmclean@wfubmc.edu

After the diagnosis of cancer in a child is made, many families complement conventional medical care with lifestyle changes including diet, exercise, environment, and mind-body therapies. Biomechanical, bioenergetic, and other therapies are also sometimes sought. These include massage, chiropractic, acupuncture/acupressure, therapeutic touch, Reiki, homeopathy, and prayer. Some of these complementary therapies have well-established roles in cancer therapy for children, whereas others are controversial and require more research.

13.              Sarang SP, Telles S. Changes in p300 following two yoga-based relaxation techniques. Int J Neurosci. 2006 Dec;116(12):1419-30. 

Swami Vivekananda Yoga Research Foundation, Bangalore, India.

Cyclic meditation (CM) is a technique that combines "stimulating" and "calming" practices, based on a statement in ancient yoga texts suggesting that such a combination may be especially helpful to reach a state of mental equilibrium. The changes in the peak latency and peak amplitude of P300 auditory event-related potentials were studied before and after the practice of cyclic meditation compared to an equal duration of supine rest in 42 volunteers (group mean age +/- SD, 27 +/- 6.3 years), from Fz, Cz, and Pz electrode sites referenced to linked earlobes. The sessions were one day apart and the order was alternated. There was reduction in the peak latencies of P300 after cyclic meditation at Fz, Cz, and Pz compared to the "pre" values. A similar trend of reduction in P300 peak latencies at Fz, Cz, and Pz was also observed after supine rest, compared to the respective "pre" values, although the magnitude of change in each case was less after supine rest compared to after cyclic meditation. The P300 peak amplitudes after CM were higher at Fz, Cz, and Pz sites compared to the "pre" values. In contrast, no significant changes were observed in the P300 peak amplitudes at Fz, Cz, and Pz after supine rest compared to the respective "pre" state. The present results support the idea that "cyclic" meditation enhances cognitive processes underlying the generation of the P300.

14.              Yetkin E, Aksoy Y, Yetkin O, Turhan H.  Beneficial effect of deep breathing on premature ventricular complexes: can it be related to the decrease in QT dispersion? Int J Cardiol. 2006 Nov 18;113(3):417-8.

It has been reported that deep breathing at 6 breaths/min is associated with reduction of premature ventricular complexes. The beneficial effect of deep breathing is supposed to be due to vagal modulation of sinoatrial and atrioventricular node. Beside the modulating effects of deep breathing, we believe that deep breathing, which is also used in yoga training, might have additional effects via decreasing QT dispersion.

15614.  Agarwal V, Gupta B. Physiological effects of transcendental meditation and physical      exercise. Indian J of Traditional Knowledge. 2006 Apr; 5(2):181-183.

15615.  Allen JJ, Schnyer RN, Chambers AS, Hitt SK, Moreno FA, Manber R. Acupuncture for depression: a randomized controlled trial. J Clin Psychiatry. 2006 Nov;67(11):1665-73.

15616.  Andrade C.  Transcendental meditation and components of the metabolic syndrome: methodological issues. Arch Intern Med. 2006 Dec 11-25;166(22):2553; author reply 2554.

15617.  Andrykowski MA, Manne SL. Are psychological interventions effective and accepted by cancer patients? I. Standards and levels of evidence. Ann Behav Med. 2006 Oct;32(2):93-7. 

15618.  Astin JA, Reilly C, Perkins C, Child WL; Susan G. Komen Breast Cancer Foundation.   Breast cancer patients' perspectives on and use of complementary and alternative medicine: a study by the Susan G. Komen Breast Cancer Foundation. J Soc Integr Oncol. 2006 Fall;4(4):157-69. 

15619.  Atkinson SA.  A nutrition odyssey: knowledge discovery, translation, and outreach. 2006 Ryley-Jeffs Memorial Lecture. Can J Diet Pract Res. 2006 Autumn;67(3):150-6. 

15620.  Bardia A, Barton DL, Prokop LJ, Bauer BA, Moynihan TJ. Efficacy of complementary and alternative medicine therapies in relieving cancer pain: a systematic review. J Clin Oncol. 2006 Dec 1;24(34):5457-64. Review. 

15621.  Barton DL, Loprinzi C, Jatoi A, Vincent A, Limburg P, Bauer B, Sood A, Good M, Bearden JD 4th, Kelaghan J, Sloan J. Can complementary and alternative medicine clinical cancer research be successfully accomplished? The Mayo Clinic-North Central Cancer Treatment Group experience. J Soc Integr Oncol. 2006 Fall;4(4):143-52. Review.

15622.  Belavadi SN. Concept of Takrabasti.  Aryavaidyan. 2006 Aug-Oct; XX(1):30-34.

15623.  Blackwell E, de Leon CF, Miller GE.  Applying mixed regression models to the analysis of repeated-measures data in psychosomatic medicine. Psychosom Med. 2006 Nov-Dec;68(6):870-8.

15624.  Bower JE. Management of cancer-related fatigue. Clin Adv Hematol Oncol. 2006 Nov;4(11):828-9. Review.

15625.  Brauer P, Dietrich L, Davidson B.  Nutrition in primary health care: using a Delphi process to design new interdisciplinary services. Can J Diet Pract Res. 2006 Autumn;Suppl:S14-29. 

15626.  Breuner CC.  Alternative and complementary therapies. Adolesc Med Clin. 2006 Oct;17(3):521-46; abstract ix. Review. 

15627.  Byrne LN, Meacham RB.  Management of post-ejaculatory perineal pain. J Androl. 2006 Nov-Dec;27(6):710-1.

15628.  Cardini F, Wade C, Regalia AL, Gui S, Li W, Raschetti R, Kronenberg F.   Clinical research in traditional medicine: priorities and methods. Complement Ther Med. 2006 Dec;14(4):282-7.

15629.  Chandre R,   JS. Sattvavajaya � the Ayurvedic approach to Psychotherapy. Aryavaidyan. 2006 Aug-Oct; XX(1):14-20.

15630.  Chandra SN, Chaurasia JP, Nigam US. Efficacy of Erandataila kalpa and virecanakarma on Amavata � A comparative study. Aryavaidyan. 2006 Aug-Oct; XX(1):21-24.

15631.  Chattopadhyay M, Hazra J, Mitra A. Efficacy of Withania somnifera in the management of stress � A clinical study. Aryavaidyan. 2006 Nov-2007 Jan; XX(2):105-108.

15632.  Chen JX, Hu LS. Traditional chinese medicine for the treatment of chronic prostatitis in China: a systematic review and meta-analysis. J Altern Complement Med. 2006 Oct;12(8):763-9. Review. 

15633.  Chung V, Liu L, Bian Z, Zhao Z, Leuk Fong W, Kum WF, Gao J, Li M. Efficacy and safety of herbal medicines for idiopathic Parkinson's disease: a systematic review. Mov Disord. 2006 Oct;21(10):1709-15. Review. 

15634.  Cindy Wang SY, Yates P. Nurses' responses to people with cancer who use complementary and alternative medicine. Int J Nurs Pract. 2006 Oct;12(5):288-94. 

15635.  Daley A, MacArthur C, McManus R, Stokes-Lampard H, Wilson S, Roalfe A, Mutrie N.  Factors associated with the use of complementary medicine and non-pharmacological interventions in symptomatic menopausal women. Climacteric. 2006 Oct;9(5):336-46. 

15636.  Demattia A, Moskowitz H, Kemper KJ, Laraque D.  Disparities in complementary and alternative medical therapy recommendations for children in two different socioeconomic communities. Ambul Pediatr. 2006 Nov-Dec;6(6):312-7.

15637.  Dennehy CE.  The use of herbs and dietary supplements in gynecology: an evidence-based review. J Midwifery Womens Health. 2006 Nov-Dec;51(6):402-9. Review. 

15638.  Dhalla S, Chan KJ, Montaner JS, Hogg RS. Complementary and alternative medicine use in British Columbia--a survey of HIV positive people on antiretroviral therapy. Complement Ther Clin Pract. 2006 Nov;12(4):242-8.

15639.  Duraipandiyan V, Ayyanar M, Ignacimuthu S. Antimicrobial activity of some ethnomedicinal plants used by Paliyar tribe from Tamil Nadu, India. BMC Complement Altern Med. 2006 Oct 17;6:35. 

15640.  Edgeworth R, Collins AE.   Self-care as a response to diarrhoea in rural Bangladesh: empowered choice or enforced adoption? Soc Sci Med. 2006 Nov;63(10):2686-97.

15641.  Edzard E.  Complementary and alternative medicine: examining the evidence. Community Pract. 2006 Oct;79(10):333-6. Review.

15642.  Eisenberg DM, Post DE, Davis RB, Connelly MT, Legedza AT, Hrbek AL, Prosser LA, Buring JE, Inui TS, Cherkin DC.  Addition of choice of complementary therapies to usual care for acute low back pain: a randomized controlled trial. Spine. 2007 Jan 15;32(2):151-8. 

15643.  Evans E, Evans J.  Changes in pharmacy students' attitudes and perceptions toward complementary and alternative medicine after completion of a required course. Am J Pharm Educ. 2006 Oct 15;70(5):105. 

15644.  Fisher P, McCarney R, Hasford C, Vickers A.  Evaluation of specific and non-specific effects in homeopathy: feasibility study for a randomised trial. Homeopathy. 2006 Oct;95(4):215-22. 

15645.  Gardani G, Cerrone R, Biella C, Mancini L, Proserpio E, Casiraghi M, Travisi O, Meregalli M, Trabattoni P, Colombo L, Giani L, Vaghi M, Lissoni P.  Effect of acupressure on nausea and vomiting induced by chemotherapy in cancer patients. Minerva Med. 2006 Oct;97(5):391-4. 

15646.  Gatchel RJ, Okifuji A.  Evidence-based scientific data documenting the treatment and cost-effectiveness of comprehensive pain programs for chronic nonmalignant pain. J Pain. 2006 Nov;7(11):779-93. Review. 

15647.  Gautam SP, Patel US. Vesicular arbuscular mycorrhizal association in some ethanomedicinal plants of Jabalpur district: some new host records. J basic appl Mycol 2005, 4(1-2), 165-7.

15648.  Ghaligi S, Nagendra HR, Bhatt R. Effect of Vedic chanting on memory and sustained attention. Indian J of Traditional Knowledge. 2006 Apr; 5(2):177-180.

15649.  Goertz CM, Niemtzow R, Burns SM, Fritts MJ, Crawford CC, Jonas WB.  Auricular acupuncture in the treatment of acute pain syndromes: A pilot study. Mil Med. 2006 Oct;171(10):1010-4. 

15650.  Grossarth-Maticek R, Ziegler R.  Prospective controlled cohort studies on long-term therapy of breast cancer patients with a mistletoe preparation (Iscador). Forsch Komplementarmed. 2006 Oct;13(5):285-92.

15651.  Guo R, Canter PH, Ernst E. Herbal medicines for the treatment of rhinosinusitis: a systematic review. Otolaryngol Head Neck Surg. 2006 Oct;135(4):496-506. Review. 

15652.  Guth AA, Diflo T.  "You've got mail!": the role of e-mail in clinical breast surgical practice. Breast. 2006 Dec;15(6):713-7.

15653.  Heymsfield SB, Harp JB, Rowell PN, Nguyen AM, Pietrobelli A.  How much may I eat? Calorie estimates based upon energy expenditure prediction equations. Obes Rev. 2006 Nov;7(4):361-70. Review. 

15654.  Hong CZ.  Treatment of myofascial pain syndrome. Curr Pain Headache Rep. 2006 Oct;10(5):345-9. Review. 

15655.  Hsieh TC, Wu JM.  Differential control of growth, cell cycle progression, and gene expression in human estrogen receptor positive MCF-7 breast cancer cells by extracts derived from polysaccharopeptide I'm-Yunity and Danshen and their combination. Int J Oncol. 2006 Nov;29(5):1215-22. 

15656.  Hsu YL, Yen MH, Kuo PL, Cho CY, Huang YT, Tseng CJ, Lee JP, Lin CC.  San-Zhong-Kui-Jian-Tang, a traditional Chinese medicine prescription, inhibits the proliferation of human breast cancer cell by blocking cell cycle progression and inducing apoptosis. Biol Pharm Bull. 2006 Dec;29(12):2388-94. 

15657.  Jadeja BA, Odedra NK, Odedra KR. Herbal remedies used for haemorrhoids by tribals of Saurashtra, Gujarat. Indian J of Traditional Knowledge. 2006 Jul; 5(3):348-352.

15658.  Jagtap SD, Deokule SS, Bhosle SV.  Some unique ethnomedicinal uses of plants used by the Korku tribe of Amravati district of Maharashtra, India. J Ethnopharmacol. 2006 Oct 11;107(3):463-9.

15659.  Javed M,  Khan AJ, Siddiqui MMH. Effect of Colchicum luteum Baker in the management of rheumatoid arthritis. Indian J of Traditional Knowledge. 2005 Oct; 4(4):421-423

15660.  Juan A, Salazar A, Alvarez A, Perez JR, Garcia L, Corbella X.  Effectiveness and safety of an emergency department short-stay unit as an alternative to standard inpatient hospitalisation. Emerg Med J. 2006 Nov;23(11):833-7. 

15661.  Kaboru BB, Falkenberg T, Ndulo J, Muchimba M, Solo K, Faxelid E; Bridging Gaps Project's Research Team.  Communities' views on prerequisites for collaboration between modern and traditional health sectors in relation to STI/HIV/AIDS care in Zambia. Health Policy. 2006 Oct;78(2-3):330-9.

15662.  Kajiyama H, Akama H, Yamanaka H, Shoji A, Matsuda Y, Tanaka E, Nakajima A, Terai C, Hara M, Tomatsu T, Saitoh T, Kamatani N.  One third of Japanese patients with rheumatoid arthritis use complementary and alternative medicine. Mod Rheumatol. 2006;16(6):355-9.

15663.  Kar A, Choudhary BK, Bandyopadhyay NG. Some common medicinal and aromatic plants for management of impaired glucose tolerance and early diabetes mellitus. Indian J nat Products 2005, 21(4), 19-24.

15664.  Kelner M, Wellman B, Welsh S, Boon H. How far can complementary and alternative medicine go? The case of chiropractic and homeopathy. Soc Sci Med. 2006 Nov;63(10):2617-27.

15665.  Kim KS, Kim DW, Yu YK.  The effect of capsicum plaster in pain after inguinal hernia repair in children. Paediatr Anaesth. 2006 Oct;16(10):1036-41. 

15666.  Kitano A, Saika S, Yamanaka O, Ikeda K, Reinach PS, Nakajima Y, Okada Y, Shirai K, Ohnishi Y.  Genipin suppresses subconjunctival fibroblast migration, proliferation and myofibroblast transdifferentiation. Ophthalmic Res. 2006;38(6):355-60.

15667.  Kittleson MM, Meoni LA, Wang NY, Chu AY, Ford DE, Klag MJ.  Association of childhood socioeconomic status with subsequent coronary heart disease in physicians. Arch Intern Med. 2006 Nov 27;166(21):2356-61. 

15668.  Kumar IR, Swamy NVC, Nagendra HR. Effect of pyramids on microorganisms. Indian J of Traditional Knowledge. 2005 Oct; 4(4):373-379.

15669.  La Torre MA. Creating a healing environment. Perspect Psychiatr Care. 2006 Nov;42(4):262-4.

15670.  Lansky EP, St Louis EK. Transcendental meditation: a double-edged sword in epilepsy? Epilepsy Behav. 2006 Nov;9(3):394-400.

15671.  Lau MA, Bishop SR, Segal ZV, Buis T, Anderson ND, Carlson L, Shapiro S, Carmody J, Abbey S, Devins G.  The Toronto Mindfulness Scale: development and validation. J Clin Psychol. 2006 Dec;62(12):1445-67. 

15672.  Lee HJ, Lee EO, Rhee YH, Ahn KS, Li GX, Jiang C, Lu J, Kim SH.  An oriental herbal cocktail, ka-mi-kae-kyuk-tang, exerts anti-cancer activities by targeting angiogenesis, apoptosis and metastasis. Carcinogenesis. 2006 Dec;27(12):2455-63.

15673.  Lee LS, Andrade AS, Flexner C.  Interactions between natural health products and antiretroviral drugs: pharmacokinetic and pharmacodynamic effects. Clin Infect Dis. 2006 Oct 15;43(8):1052-9.

15674.  Leung AY, Park J, Schulteis G, Duann JR, Yaksh T.  The electrophysiology of de qi sensations. J Altern Complement Med. 2006 Oct;12(8):743-50.  

15675.  Lie DA, Boker J.  Comparative survey of Complementary and Alternative Medicine (CAM) attitudes, use, and information-seeking behaviour among medical students, residents & faculty. BMC Med Educ. 2006 Dec 9;6:58. 

15676.  Lim B, Manheimer E, Lao L, Ziea E, Wisniewski J, Liu J, Berman B.  Acupuncture for treatment of irritable bowel syndrome. Cochrane Database Syst Rev. 2006 Oct 18;(4):CD005111. Review. 

15677.  Lin CM, Chang H, Chen YH, Wu IH, Chiu JH.  Wogonin inhibits IL-6-induced angiogenesis via down-regulation of VEGF and VEGFR-1, not VEGFR-2. Planta Med. 2006 Nov;72(14):1305-10.

15678.  Liu T, Liu C.  Acupuncture for treating osteoarthritis of the knee and the hip. Arthritis Rheum. 2006 Nov;54(11):3375-7.

15679.  Lokhande PD, Jagdale SC, Chabukswar AR. Natural remedies for heart diseases. Indian J of Traditional Knowledge. 2006 Jul; 5(3):420-427.

15680.  Ma YX, Fu HZ, Li M, Sun W, Xu B, Cui JR.  An anticancer effect of a new saponin component from Gymnocladus chinensis Baillon through inactivation of nuclear factor-kappaB. Anticancer Drugs. 2007 Jan;18(1):41-6. 

15681.  Macklin EA, Wayne PM, Kalish LA, Valaskatgis P, Thompson J, Pian-Smith MC, Zhang Q, Stevens S, Goertz C, Prineas RJ, Buczynski B, Zusman RM.  Stop Hypertension with the Acupuncture Research Program (SHARP): results of a randomized, controlled clinical trial. Hypertension. 2006 Nov;48(5):838-45.

15682.  Malhotra V, Tandon O P. A study of the effect of individual Asanas on blood pressure. Indian J of Traditional Knowledge. 2005 Oct; 4(4):367-372.

15683.  Mangal A, Panda D, Sharma MC. Peptic ulcer healing properties of Shatavari (Asparagus racemosus Willd.). Indian J of Traditional Knowledge. 2006 Apr; 5(2):227-228.

15684.  Mangalasseri P. Ayurvedic Approach to Parkinsonism. Aryavaidyan. 2006 Nov-2007 Jan; XX(2):121-128.

15685.  Maroon JC, Bost JW, Borden MK, Lorenz KM, Ross NA.  Natural antiinflammatory agents for pain relief in athletes. Neurosurg Focus. 2006 Oct 15;21(4):E11. Review. 

15686.  Matt P, Carrel T, White M, Lefkovits I, Van Eyk J.   Proteomics in cardiovascular surgery. J Thorac Cardiovasc Surg. 2007 Jan;133(1):210-4. Review. 

15687.  McEachrane-Gross FP, Liebschutz JM, Berlowitz D.  Use of selected complementary and alternative medicine (CAM) treatments in veterans with cancer or chronic pain: a cross-sectional survey. BMC Complement Altern Med. 2006 Oct 6;6:34. 

15688.  Merida I, Avila-Flores A.  Tumor metabolism: new opportunities for cancer therapy. Clin Transl Oncol. 2006 Oct;8(10):711-6. Review. 

15689.  Moussavi Z, Behrouzi R. Over-the-counter and alternative medicines in the treatment of vulvovaginal symptoms in women referred to the Gynecologic clinics. J Cell Tissue Res 2005, 5(2), 453-6.

15690.  Nahin RL, Fitzpatrick AL, Williamson JD, Burke GL, Dekosky ST, Furberg C; GEM Study Investigators.  Use of herbal medicine and other dietary supplements in community-dwelling older people: Baseline data from the ginkgo evaluation of memory study. J Am Geriatr Soc. 2006 Nov;54(11):1725-35. 

15691.  Niscola P, de Fabritiis P, Cartoni C, Romani C, Sorrentino F, Dentamaro T, Piccioni D, Scaramucci L, Giovannini M, Amadori S, Mandelli F.  Home care management of patients affected by hematologic malignancies: a review. Haematologica. 2006 Nov;91(11):1523-9. Review. 

15692.  O'Dowd A.  New rules for homoeopathic remedies anger UK peers. BMJ. 2006 Nov 4;333(7575):935. 

15693.  Park YK, Soh CT, Park GM, Hwang MK, Chung PR.  Host specificity of Pisidium coreanum (Bivalvia: Sphaeriidae) to larval infection with a human intestinal fluke Echinostoma cinetorchis (Trematoda: Echinostomatidae) in Korea. J Parasitol. 2006 Oct;92(5):1118-20.

15694.  Patel G, Euler D, Audette JF. Complementary and alternative medicine for noncancer pain. Med Clin North Am. 2007 Jan;91(1):141-67. Review. 

15695.  Pawar S,  Patil D A. Folk remedies against rheumatic disorders in Jalgaon district, Maharashtra. Indian J of Traditional Knowledge. 2006 Jul; 5(3):314-316.

15696.  Pilkington K, Rampes H, Richardson J.  Complementary medicine for depression. Expert Rev Neurother. 2006 Nov;6(11):1741-51. Review. 

15697.  Pitsios C, Chliva C, Mikos N, Kompoti E, Nowak-Wegrzyn A, Kontou-Fili K.  Bee pollen sensitivity in airborne pollen allergic individuals. Ann Allergy Asthma Immunol. 2006 Nov;97(5):703-6. 

15698.  Prashant V, Akhila, Harishchandra H, D�souza V, D�souza B. Antioxidant and membrane stabilizing effect of vitamin E in elderly people. Aryavaidyan. 2006 May-Jul; XIX(4):237-241.

15699.  Rajagopala M, Singh KD, Singh K. Myopia � A clinical study. Aryavaidyan. 2006 May-Jul; XIX(4):221-225.

15700.  Robinson N, Donaldson J, Watt H.  Auditing outcomes and costs of integrated complementary medicine provision�the importance of length of follow up. Complement Ther Clin Pract. 2006 Nov;12(4):249-57.

15701.  Robotin MC, Penman AG.  Integrating complementary therapies into mainstream cancer care: which way forward? Med J Aust. 2006 Oct 2;185(7):377-9. 

15702.  Samdup DZ, Smith RG, Il Song S.  The use of complementary and alternative medicine in children with chronic medical conditions. Am J Phys Med Rehabil. 2006 Oct;85(10):842-6.

15703.  Saydah SH, Eberhardt MS.  Use of complementary and alternative medicine among adults with chronic  diseases: United States 2002. J Altern Complement Med. 2006 Oct;12(8):805-12. 

15704.  Sedgeman JA, Sarwari A.  The effect of a Health Realization/Innate Health psychoeducational seminar on stress and anxiety in HIV-positive patients. Med Sci Monit. 2006 Oct;12(10):CR397-9.

15705.  Shamseer L, Charrois TL, Vohra S; American Academy of Pediatrics Provisional Section on Complementary, Holistic, and Integrative Medicine.  Complementary, holistic, and integrative medicine: garlic. Pediatr Rev. 2006 Dec;27(12):e77-80. Review.

15706.  Shannahoff-Khalsa D.  A perspective on the emergence of meditation techniques for medical disorders. J Altern Complement Med. 2006 Oct;12(8):709-13.

15707.  Sharma JM, Singh DJ, Sambath. Comparative study of two anti-diabetic ayurvedic formulations. Aryavaidyan. 2006 May-Jul; XIX(4):205-210.

15708.  Shaw A, Thompson EA, Sharp DJ.  Expectations of patients and parents of children with asthma regarding access to complementary therapy information and services via the NHS: a qualitative study. Health Expect. 2006 Dec;9(4):343-58. 

15709.  Sikarwar RLS, Jaiswal A, Chaturvedi A. Uses of some important medicinal plants of Chitrakoot region of Satna (M.P.). natn J Life Sci 2004, 1(2), 349-52.

15710.  Singh S. Impact of vegetarian diet, aerobic exercise and rajyoga meditation on hyperinsulinemia, dyslipidemia and homocysteinemia in coronary artery diseases. Biomedical Science Dep, University of Delhi, Delhi, 2006.

15711.  Sing S, Jain CM, Khawale DS. Childhood obesity: A conceptual study. Aryavaidyan. 2006 Aug-Oct; XX(1):14-20.

15712.  Steen M, Calvert J.  Homeopathy for childbirth: remedies and research. RCM Midwives. 2006 Nov;9(11):438-40. Review.

15713.  Steffen KJ, Roerig JL, Mitchell JE, Crosby RD.  A survey of herbal and alternative medication use among participants with eating disorder symptoms. Int J Eat Disord. 2006 Dec;39(8):741-6.

15714.  Swarup AB, Barrett W, Jazieh AR. The use of complementary and alternative medicine by cancer patients undergoing radiation therapy. Am J Clin Oncol. 2006 Oct;29(5):468-73.

15715.  Takakuwa K, Ooki I, Nonaka T, Tamura N, Ishii K, Kikuchi A, Tamura M, Tanaka K.   Prophylactic therapy for patients with reproductive failure who were positive for anti- phospholipid antibodies. Am J Reprod Immunol. 2006 Oct;56(4):237-42. 

15716.  Teixeira MZ.  Evidence of the principle of similitude in modern fatal iatrogenic events. Homeopathy. 2006 Oct;95(4):229-36. Review. 

15717.  Telles S, Naveen KV.  Effect of yoga on somatic indicators of distress in professional computer users. Med Sci Monit. 2006 Oct;12(10):LE21-2.

15718.  Travis F, Arenander A. Cross-sectional and longitudinal study of effects of transcendental meditation practice on interhemispheric frontal asymmetry and frontal coherence. Int J Neurosci. 2006 Dec;116(12):1519-38. 

15719.  Ukiya M, Akihisa T, Yasukawa K, Tokuda H, Suzuki T, Kimura Y. Anti-inflammatory, anti-tumor-promoting, and cytotoxic activities of constituents of marigold (Calendula officinalis) flowers. J Nat Prod. 2006 Dec;69(12):1692-6. 

15720.  Unnikrishnan P. Excerpts from Cikitsamanjari � LII. Aryavaidyan. 2006 Aug-Oct; XX(1):57-64.

15721.        Viggo Hansen N, Jorgensen T, Ortenblad L.  Massage and touch for dementia. Cochrane Database Syst Rev. 2006 Oct 18;(4):CD004989. Review.

15722.  Wadnap N, Johnson J, Bhatt N & Chitre D. Efficacy and safety of RA-11 (O) � A herbal analgesic cream.  Indian J of Traditional Knowledge2006 July; 5(3):384-387.

15723.  Wang CY, Chiao MT, Yen PJ, Huang WC, Hou CC, Chien SC, Yeh KC, Yang WC, Shyur LF, Yang NS.  Modulatory effects of Echinacea purpurea extracts on human dendritic cells: a cell- and gene-based study. Genomics. 2006 Dec;88(6):801-8.

15724.  Welder GJ, Wessel TR, Arant CB, Schofield RS, Zineh I.  Complementary and alternative medicine use among individuals participating in research: implications for research and practice. Pharmacotherapy. 2006 Dec;26(12):1794-801. 

15725.  Wells M, Sarna L, Cooley ME, Brown JK, Chernecky C, Williams RD, Padilla G, Danao LL.  Use of complementary and alternative medicine therapies to control symptoms in women living with lung cancer. Cancer Nurs. 2007 Jan-Feb;30(1):45-55; quiz 56-7.

15726.  White A.  Acupuncture for tinnitus: a series of six n = 1 controlled trials. Complement Ther Med. 2006 Dec;14(4):289; author reply 288.

15727.  Wickham S.  Holistic therapies, proof and plausibility. Pract Midwife. 2006 Nov;9(10):51.

15728.  Williams J, Russell I, Durai D, Cheung WY, Farrin A, Bloor K, Coulton S, Richardson G. What are the clinical outcome and cost-effectiveness of endoscopy undertaken by nurses when compared with doctors? A Multi-Institution Nurse Endoscopy Trial (MINuET). Health Technol Assess. 2006 Oct;10(40):iii-iv, ix-x, 1-195.

15729.  Wu PL, Hsu YL, Jao CW.  Indole alkaloids from Cephalanceropsis gracilis. J Nat Prod. 2006 Oct;69(10):1467-70. 

15730.  Wu T, Harrison RA, Chen X, Ni J, Zhou L, Qiao J, Wang Q, Wei J, Xin D, Zheng J.   Tongxinluo (Tong xin luo or Tong-xin-luo) capsule for unstable angina pectoris. Cochrane Database Syst Rev. 2006 Oct 18;(4):CD004474. Review. 

15731.  Yamada K. Quality of life in patients treated with Kampo medicine: a complementary alternative to modern medicine. J Altern Complement Med. 2006 Oct;12(8):799-803. 

15732.  Yuan HL, Yang M, Li XY, You RH, Liu Y, Zhu J, Xie H, Xiao XH.  Hepatitis B virus inhibiting constituents from Herpetospermum caudigerum. Chem Pharm Bull (Tokyo). 2006 Nov;54(11):1592-4.

15733.  Zhang XP, Li ZJ, Liu DR.  Progress in research into the mechanism of Radix salviae miltiorrhizae in treatment of acute pancreatitis. Hepatobiliary Pancreat Dis Int. 2006 Nov;5(4):501-4. Review. 

15734.  Zwelling E, Johnson K, Allen J.  How to implement complementary therapies for laboring women. MCN Am J Matern Child Nurs. 2006 Nov-Dec;31(6):364-70; quiz 371-2. 

 

Back

July 2007

Selected abstracts:

1.                  Bernardi L, Passino C, Spadacini G, Bonfichi M, Arcaini L, Malcovati L, Bandinelli G, Schneider A, Keyl C, Feil P, Greene RE, Bernasconi C. Reduced hypoxic ventilatory response with preserved blood oxygenation in yoga trainees and Himalayan Buddhist monks at altitude: evidence of a different adaptive strategy? Eur J Appl Physiol. 2007 Mar;99(5):511-8
Department of Internal Medicine, University of Pavia and IRCCS Ospedale S. Matteo, Pavia, Italy.
Yoga induces long-term changes in respiratory function and control. We tested whether it represents a successful strategy for high-altitude adaptation. We compared ventilatory, cardiovascular and hematological parameters in: 12 Caucasian yoga trainees and 12 control sea-level residents, at baseline and after 2-week exposure to high altitude (Pyramid Laboratory, Nepal, 5,050 m), 38 active lifestyle high-altitude natives (Sherpas) and 13 contemplative lifestyle high-altitude natives with practice of yoga-like respiratory exercises (Buddhist monks) studied at 5,050 m. At baseline, hypoxic ventilatory response (HVR), red blood cell count and hematocrit were lower in Caucasian yoga trainees than in controls. After 14 days at altitude, yoga trainees showed similar oxygen saturation, blood pressure, RR interval compared to controls, but lower HVR (-0.44 +/- 0.08 vs. -0.98 +/- 0.21 l/min/m/%SaO(2), P < 0.05), minute ventilation (8.3 +/- 0.9 vs. 10.8 +/- 1.6 l/min, P < 0.05), breathing rate (indicating higher ventilatory efficiency), and lower red blood cell count, hemoglobin, hematocrit, albumin, erythropoietin and soluble transferrin receptors. Hypoxic ventilatory response in monks was lower than in Sherpas (-0.23 +/- 0.05 vs. -0.63 +/- 0.09 l/min/m/%SaO(2), P < 0.05); values were similar to baseline data of yoga trainees and Caucasian controls, respectively. Red blood cell count and hematocrit were lower in monks as compared to Sherpas. In conclusion, Caucasian subjects practicing yoga maintain a satisfactory oxygen transport at high altitude, with minimal increase in ventilation and with reduced hematological changes, resembling Himalayan natives. Respiratory adaptations induced by the practice of yoga may represent an efficient strategy to cope with altitude-induced hypoxia.

2.                  Biziulevicius GA, Kazlauskaite J. Following Hippocrates' advice 'Let food be thy medicine and medicine be thy food': an alternative method for evaluation of the immunostimulatory potential of food proteins. Med Hypotheses. 2007;68(3):712-3. Complementary Medicine, Peninsula Medical School, University of Exeter, Exeter, United Kingdom.
OBJECTIVE: To assess the evidence of any type of therapeutic or preventive intervention testing homeopathy for childhood and adolescence ailments. METHODS: Systematic literature searches were conducted through January 2006 in MEDLINE, EMBASE, AMED, CINAHL, Cochrane Central, British Homeopathic Library, ClinicalTrials.gov, and the UK National Research Register. Bibliographies were checked for further relevant publications. Studies were selected according to predefined inclusion and exclusion criteria. All double-blind, placebo-controlled randomized clinical trials of any homeopathic intervention for preventing or treating childhood and adolescence ailments were included. According to the classification of the World Health Organization, the age range defined for inclusion was 0 to 19 years. Study selection, data extraction, and assessment of methodological quality were performed independently by 2 reviewers. RESULTS: A total of 326 articles were identified, 91 of which were retrieved for detailed evaluation. Sixteen trials that assessed 9 different conditions were included in the study. With the exception of attention-deficit/hyperactivity disorder and acute childhood diarrhea (each tested in 3 trials), no condition was assessed in more than 2 double-blind randomized clinical trials. The evidence for attention-deficit/hyperactivity disorder and acute childhood diarrhea is mixed, showing both positive and negative results for their respective main outcome measures. For adenoid vegetation, asthma, and upper respiratory tract infection each, 2 trials are available that suggest no difference compared with placebo. For 4 conditions, only single trials are available. CONCLUSION: The evidence from rigorous clinical trials of any type of therapeutic or preventive intervention testing homeopathy for childhood and adolescence ailments is not convincing enough for recommendations in any condition.

3.                  Bradley R, Oberg EB, Calabrese C, Standish LJ.  Algorithm for complementary and alternative medicine practice and research in type 2 diabetes. J Altern Complement Med. 2007 Jan-Feb;13(1):159-75. Review.  
Bastyr University, Kenmore, WA 98028, USA. rbradley@bastyr.edu
OBJECTIVE: To develop a model to direct the prescription of nutritional and botanical medicines in the treatment of type 2 diabetes for both clinical and research purposes. METHODS: Available literature on nutritional and botanical medicines was reviewed and categorized as follows: antioxidant/anti-inflammatory; insulin sensitizer; and beta-cell protectant/insulin secretagogue. Literature describing laboratory assessment for glycemic control, insulin resistance, and beta-cell reserve was also reviewed and a clinical decision tree was developed. RESULTS: Clinical algorithms were created to guide the use of nutritional and botanic medicines using validated laboratory measures of glycemic control, insulin sensitivity, and beta-cell reserve. Nutrient and botanic medicines with clinical trial research support include coenzyme Q10, carnitine, alpha-lipoic acid, N-acetylcysteine, vitamin D, vitamin C, vitamin E, chromium, vanadium, omega-3 fatty acids, cinnamon (Cinnamomum cassia), fenugreek (Trigonella foenum-graecum), and gymnema (Gymnema sylvestre). CONCLUSIONS: Clinical algorithms can direct supplementation in clinical practice and provide research models for clinical investigation. Algorithms also provide a framework for integration of future evidence as it becomes available. Research funding to investigate potentially beneficial practices in complementary medicine is critically important for optimal patient care and safety.

4.                  Carson JW, Carson KM, Porter LS, Keefe FJ, Shaw H, Miller JM.  Yoga for women with metastatic breast cancer: results from a pilot study. J Pain Symptom Manage. 2007 Mar;33(3):331-41.  
Department of Psychiatry and Behavioral Sciences, Duke University Medical Center, Durham, North Carolina 27708, USA. jim.carson@duke.edu
Metastatic breast cancer (MBC) remains a terminal illness for which major treatment advances are slow to appear, and hence it is crucial that effective palliative interventions be developed to reduce the cancer-related symptoms of women with this condition during the remaining years of their lives. This pilot/feasibility study examined a novel, yoga-based palliative intervention, the Yoga of Awareness Program, in a sample of women with MBC. The eight-week protocol included gentle yoga postures, breathing exercises, meditation, didactic presentations, and group interchange. Outcome was assessed using daily measures of pain, fatigue, distress, invigoration, acceptance, and relaxation during two preintervention weeks and the final two weeks of the intervention. Thirteen women completed the intervention (mean age=59; mean time since diagnosis=7 years; two African American, 11 Caucasian). During the study, four participants had cancer recurrences, and the physical condition of several others deteriorated noticeably. Despite low statistical power, pre-to-post multilevel outcomes analyses showed significant increases in invigoration and acceptance. Lagged analyses of length of home yoga practice (controlling for individual mean practice time and outcome levels on the lagged days) showed that on the day after a day during which women practiced more, they experienced significantly lower levels of pain and fatigue, and higher levels of invigoration, acceptance, and relaxation. These findings support the need for further investigation of the effects of the Yoga of Awareness Program in women with MBC.

5.                  Comhaire F, Mahmoud A.  Preventing diseases of the prostate in the elderly using hormones and nutriceuticals. Aging Male. 2004 Jun;7(2):155-69. Review. 
Ghent University Hospital, Gent, Belgium.
The prostate has only one function, namely to secrete fluid containing substances that are needed for reproduction. This requires an extremely high concentration of androgens in the tissues. Benign prostatic hypertrophy (BPH) seems to be related to the long-term exposure of the prostate to the strong androgen 5alpha-dihydrotestosterone (DHT) and, possibly, to estrogens. The relation between prostate cancer and androgens is suggested to be U-shaped, with both extremes of androgen concentrations being associated with increased risk of invasive cancer. In the treatment of patients with BPH, the lipidic liposterolic extracts of Serenoa repens were as effective as the pharmaceutical inhibitors of the 5alpha-reductase enzyme or alpha1-adrenergic blockers in relieving urinary symptoms. In addition to moderately inhibiting the 5alpha-reductase activity, Serenoa seems to exert anti-inflammatory and complementary cellular actions with beneficial effects on the prostate. Unlike the pharmaceutical 5alpha-reductase inhibitors, finasteride and dutasteride, Serenoa does not suppress serum PSA, facilitating the follow-up and the early detection of prostate cancer. We suggest a strategy to prevent prostate cancer that aims at providing men with partial androgen deficiency correct testosterone substitution with a sustained release buccal bio-adhesive tablet. In addition, food supplementation with extracts of Serenoa repens and a combination of the antioxidants selenium, (cis)-lycopene and natural vitamin E, together with fish oil rich in long-chain polyunsaturated essential fatty acids of the omega-3 group seems warranted. Clearly, a holistic approach including careful clinical and biological monitoring of the aging man and his prostate remains mandatory.

6.                  Garofalo C, Vignaroli C, Zandri G, Aquilanti L, Bordoni D, Osimani A, Clementi F, Biavasco F.  Direct detection of antibiotic resistance genes in specimens of chicken and pork meat. Int J Food Microbiol. 2007 Jan 1;113(1):75-83.

Department of Food Sciences, Universit� Politecnica delle Marche, via Ranieri, Montedago, 60131 Ancona, Italy.

Antibiotic resistance (AR) in bacteria, a major threat to human health, has emerged in the last few decades as a consequence of the selective pressure exerted by the widespread use of antibiotics in medicine, agriculture and veterinary practice and as growth promoters in animal husbandry. The frequency of 11 genes [tet(M), tet(O), tet(K), erm(A), erm(B), erm(C), vanA, vanB, aac (6')-Ie aph (2'')-Ia, mecA, blaZ] encoding resistance to some antibiotics widely used in clinical practice was analysed in raw pork and chicken meat and in fermented sausages as well as in faecal samples from the relevant farm animals using a molecular approach based on PCR amplification of bacterial DNA directly extracted from specimens. Some of the 11 AR genes were highly prevalent, the largest number being detected in chicken meat and pig faeces. The genes found most frequently in meat were tet(K) and erm(B); vanB and mecA were the least represented. All 11 determinants were detected in faecal samples except mecA, which was found only in chicken faeces. erm(B) and erm(C) were detected in all faecal samples. The frequency of AR genes was not appreciably different in meat compared to faecal specimens of the relevant animal except for vanB, which was more prevalent in faeces. Our findings suggest that AR genes are highly prevalent in food-associated bacteria and that AR contamination is likely related to breeding rather than processing techniques. Finally, the cultivation-independent molecular method used in this work to determine the prevalence of AR genes in foods proved to be a rapid and reliable alternative to traditional tools.

7.                  Jayadevappa R, Johnson JC, Bloom BS, Nidich S, Desai S, Chhatre S, Raziano DB, Schneider R. Effectiveness of transcendental meditation on functional capacity and quality of life of African Americans with congestive heart failure: a randomized control study.  Ethn Dis. 2007 Winter;17(1):172-3.
Department of Medicine, University of Pennsylvania, 224, Ralston-Penn Center, 3615 Chestnut Street, Philadelphia, PA 19104-2676, USA. jravi@mail.med.upenn.edu
OBJECTIVE: To evaluate the effectiveness of a Transcendental Meditation (TM) stress reduction program for African Americans with congestive heart failure (CHF). DESIGN: Randomized, controlled study PARTICIPANTS AND INTERVENTION: We recruited 23 African American patients > or = 55 years of age who were recently hospitalized with New York Heart Association class II or III CHF and with an ejection fraction of < .40. Participants were randomized to either TM or health education (HE) group. MAIN OUTCOME MEASURES: Primary outcome measure was six-minute walk test; secondary outcomes were generic and disease-specific health-related quality of life, quality of well being, perceived stress, Center for Epidemiologic Studies Depression Scale (CES-D), rehospitalizations, brain natriuretic peptide, and cortisol. Changes in outcomes from baseline to three and six months after treatment were analyzed by using repeated measures analysis of variance, covarying for baseline score. RESULTS: For the primary outcome of functional capacity, the TM group significantly improved on the six-minute walk test from baseline to six months after treatment compared to the HE group (P = .034). On the secondary outcome measures, the TM group showed improvements in SF-36 subscales and total score on the Minnesota Living with Heart Failure scale. On the CES-D, the TM group showed significant decrease from baseline to six months compared to the HE group (P = .03). Also, the TM group had fewer rehospitalizations during the six months of followup. CONCLUSIONS: Results indicate that TM can be effective in improving the quality of life and functional capacity of African American CHF patients. Further validation of outcomes is planned via a large, multicenter trial with long-term follow-up.

8.                  Knox J, Gaster B.  Dietary supplements for the prevention and treatment of coronary artery disease. J Altern Complement Med. 2007 Jan-Feb;13(1):83-95.
Department of Medicine, University of Washington, Seattle, WA, USA.
PURPOSE: With the recent growth in the use of dietary supplements, it is increasingly important for clinicians to be familiar with the evidence for and against their efficacy. We set out to systematically review the dietary supplements available for the prevention and treatment of coronary artery disease. METHODS: Between May 2004 and May 2006, we searched MEDLINE, the Cochrane Library, and Pro-Quest using the MeSH terms hypertension, hypercholesterolemia, myocardial infarction, dietary supplements, and herb-drug interactions. The MeSH terms of individual supplements identified were then added to the search. Reference lists of pertinent papers were also searched to find appropriate papers for inclusion. We included randomized controlled trials published in English of at least 1 week's duration that studied the efficacy of supplements in the treatment of hypercholesterolemia, or hypertension, or in the prevention of cardiac events. Qualifying papers were identified and assigned a Jadad quality score. In areas of uncertainty, a second investigator independently scored the trial. RESULTS: Fifteen (15) supplements were identified. Of these, most had little data available and most of the data were of poor quality. The supplements with the most supporting data were policosanol and garlic, both for hyperlipidemia. CONCLUSIONS: A growing body of literature exists for numerous supplements in the prevention of coronary artery disease, but much of these data are inconclusive. Clinicians should become familiar with the extent and limitations of this literature so that they may counsel their patients better.

9.                  Krishnamurthy MN, Telles S. Assessing depression following two ancient Indian interventions: effects of yoga and ayurveda on older adults in a residential home. J Gerontol Nurs. 2007 Feb;33(2):17-23. 
Division of Life Sciences, Swami Vivekananda Yoga University, Bangalore, India.
The effects of yoga and ayurveda on geriatric depression were evaluated in 69 persons older than 60 who were living in a residential home. Participants were stratified by age and gender and randomly allocated to three groups: Yoga, Ayurveda, or Wait-list Control. The 15-item Geriatric Depression Scale was used to assess depressive symptoms prior to the intervention, and after 3 months and 6 months post-intervention. Participation in one of the three groups lasted 24 weeks. The yoga program (7 hours 30 minutes per week) included physical postures, relaxation techniques, regulated breathing, devotional songs, and lectures. The Ayurveda Group received an herbal preparation twice daily for the whole period. The depression symptom scores of the Yoga Group at both 3 and 6 months decreased significantly, from a group average baseline of 10.6 to 8.1 and 6.7, respectively (p < .001, paired t-test). The other groups showed no change. Hence, an integrated approach of yoga including the mental and philosophical aspects in addition to the physical practices was useful for institutionalized older persons.

10.              Prajapati SH, Kahn RF, Stecker T, Pulley L.  Curriculum planning: a needs assessment for complementary and alternative medicine education in residency. Fam Med. 2007 Mar;39(3):190-4.  
Department of Family and Preventive Medicine, University of Arkansas, Little Rock, AR 72205-7199, USA. PrajapatiSaritaH@uams.edu
BACKGROUND AND OBJECTIVES: The curricular needs in complementary and alternative medicine (CAM) of family medicine residents are unknown. Our objective was to assess perceptions of knowledge, attitudes, practice behaviors, and interest toward CAM by family medicine residents. METHODS: A questionnaire was administered to family medicine residents (n=153) throughout one state. RESULTS: The response rate was 77% (118/153), with an equal distribution of first-, second-, and third-year residents. Respondents reported minimal knowledge of CAM and low awareness of CAM resources. Many do not routinely ask patients about their CAM usage. Most respondents reported discomfort advising their patients of the risks and benefits of CAM therapies, and most were interested in learning about CAM. While prior training made a difference in responses, gender and training level did not. Whites were more likely to have had prior training in CAM than non-whites. CONCLUSIONS: Family medicine residents in Arkansas may not have enough training in CAM. Given the growing popularity of these modalities among the general public, residents might benefit from training and education in CAM.

11.              Putnam SE, Scutt AM, Bicknell K, Priestley CM, Williamson EM.  Natural products as alternative treatments for metabolic bone disorders and for maintenance of bone health. Phytother Res. 2007 Feb;21(2):99-112. Review. 
School of Pharmacy, University of Reading, Whiteknights, Reading RG6 6AJ, UK.
Bone metabolism involves a complex balance between the deposition of matrix and mineralization and resorption. There is now good evidence that dietary components and herbal products can influence these processes, particularly by inhibiting bone resorption, thus having beneficial effects on the skeleton. For example, it has been reported that a number of common vegetables, including onion, garlic and parsley, can inhibit bone resorption in ovariectomized rats. Essential oils derived from sage, rosemary, thyme and other herbs inhibit osteoclast activity in vitro and in vitro and leading to an increase in bone mineral density. Soya, a rich source of isoflavones, has shown promising results and epidemiological evidence to support a use in maintaining bone health, and various traditional herbal formulae in Chinese and Ayurvedic medicine also have demonstrable effects in pharmacological models of osteoporosis. Recently, cannabinoids have been described as having positive effects on osteoblast differentiation, and the presence of cannabinoid receptors in bone tissue indicates a more complex role in bone metabolism than previously thought. The first part of this review briefly discusses normal bone metabolism and disorders caused by its disruption, with particular reference to osteoporosis and current pharmacological treatments. The effects of natural products on bone and connective tissue are then discussed, to include items of diet, herbal extracts and food supplements, with evidence for their efficacy outlined. Copyright (c) 2006 John Wiley & Sons, Ltd.

12.              Sawni A, Ragothaman R, Thomas RL, Mahajan P.  The use of complementary/alternative therapies among children attending an urban pediatric emergency department. Clin Pediatr (Phila). 2007 Jan;46(1):36-41. 

 Division of Adolescent Medicine, Children's Hospital of Michigan, Wayne State University School of Medicine, Detroit, Michigan 48201, USA.

The incidence of and factors associated with complementary/alternative medicine use by pediatric patients was determined by face-to-face interviews with 602 parents/caregivers of children aged birth to 18 years who presented to an urban pediatric emergency department from February 2004 to September 2004. The overall use of complementary/alternative medicine among children was 15% and more common among children older than 5 years (21%). Families who used complementary/alternative medicine thought results were best when both complementary/alternative medicine and conventional medicine were integrated (P < .001). Most common types of complementary/alternative therapies used were folk remedies/home remedies (59%), herbs (41%), prayer healing (14%), and massage therapy (10%). Complementary/alternative medicine use was significant among the sample of children visiting an urban pediatric emergency department. Pediatricians should inquire about complementary/alternative use in the emergency department, particularly in children older than 5 years and those with parents/caretakers using complementary/alternative medicine themselves.

13.              Sharpe PA, Blanck HM, Williams JE, Ainsworth BE, Conway JM. Use of complementary and alternative medicine for weight control in the United States. J Altern Complement Med. 2007 Mar;13(2):217-22. 

Prevention Research Center, Arnold School of Public Health, University of South Carolina, Columbia, SC 29208, USA. pasharpe@sc.edu

OBJECTIVES: The purpose was to assess the prevalence and correlates of complementary and alternative medicine use for weight control. DESIGN: A list-assisted random-digit-dialed telephone survey of adults was conducted in the fall of 2002 (n = 11,211). The focus of the study was complementary and alternative medicine (CAM) use, other than dietary supplements, in the previous 12 months. SETTINGS/LOCATION: The sample of respondents was drawn from the total noninstitutionalized U.S. adult population residing in telephone-equipped locations. SUBJECTS: The sampling procedures were designed to obtain adequate representation of Hispanic and non-Hispanic black respondents. Data from the total sample of 11,211 were weighted to achieve an estimate of the U.S. population. Analyses focused on 372 people who had used CAM within the previous 12 months. RESULTS: Of the total, 3.3% (n = 372) had used a CAM therapy in the previous 12 months. Higher adjusted odds ratios for CAM use were found among respondents who were exercising for weight control; using a lower carbohydrate, higher protein diet; using a nonprescription weight-loss product(s); overweight; physically active; and not satisfied with one's body (adjusted for age, race, gender, education, and city size). The most often used therapies were yoga (57.4%), meditation (8.2%), acupuncture (7.7%), massage (7.5%), and Eastern martial arts (5.9%). CAM users used CAM therapies on their own (62.6%), in a group setting (26.8%) or with a CAM practitioner (10.6%). CONCLUSIONS: The use of CAM therapies other than dietary supplements for weight loss was relatively low. The most popular therapy was yoga, and the majority of CAM users used CAM therapies on their own. Persons who had used other weight loss methods had greater odds for using CAM in the previous 12 months, suggesting that CAM use is often added to other weight-loss strategies.

14.              Yu D, Morris-Natschke SL, Lee KH.  New developments in natural products-based anti-AIDS research. Med Res Rev. 2007 Jan;27(1):108-32. Review.  
Natural Products Research Laboratories, School of Pharmacy, University of North Carolina, Chapel Hill, North Carolina 27599, USA.
This review discusses anti-HIV natural products from several compound classes, including terpenoids, coumarins, alkaloids, polyphenols, tannins, and flavonoids. Natural products can provide novel anti-AIDS chemotherapeutic leads that are structurally unique or have new mechanisms of action. The drug discovery and development process proceeds from bioactivity-directed isolation and identification of a promising lead natural product, followed by rational design-based structural modification and structure-activity relationship analyses to optimize the lead compound as a drug candidate. This process is notably exemplified by the discovery of the modified betulinic acid derivative, DSB [PA-457], which is currently in Phase II clinical trial and is the first-in-class HIV maturation inhibitor (MI). Copyright 2006 Wiley Periodicals, Inc.

16118.  Abrams DI. An overview of integrative oncology. Clin Adv Hematol Oncol. 2007 Jan;5(1):45-7.

16119.  Adler RC.  Wellness can be achieved through u nderstanding and addressing the elements of metabolic syndrome. J Altern Complement Med. 2007 Jan-Feb;13(1):11-2.

16120.  Allamwar SS, Rajurkar SR. Studies on hypolipidemic activity of Trigonella foenum-graecum in experimentally induced diabetic rats. Aryavaidyan 2007, 20(3), 210-215.

16121.  Allen-Hall L, Cano P, Arnason JT, Rojas R, Lock O, Lafrenie RM.  Treatment of THP-1 cells with Uncaria tomentosa extracts differentially regulates the expression if IL-1beta and TNF-alpha. J Ethnopharmacol. 2007 Jan 19;109(2):312-7.

16122.  Altunc U, Pittler MH, Ernst E.  Homeopathy for childhood and adolescence ailments: systematic review of randomized clinical trials. Mayo Clin Proc. 2007 Jan;82(1):69-75. Review. 

16123.  Aminoff BZ.  The new Israeli Law "The Dying Patient" and Relief of Suffering Units. Am J Hosp Palliat Care. 2007 Feb-Mar;24(1):54-8. 

16124.  Arranz L, Guayerbas N, Siboni L, De la Fuente M.  Effect of acupuncture treatment on the immune function impairment found in anxious women. Am J Chin Med. 2007;35(1):35-51. 

16125.  Ashrafian H, Watkins H. Reviews of translational medicine and genomics in cardiovascular disease: new disease taxonomy and therapeutic implications cardiomyopathies: therapeutics based on molecular phenotype. J Am Coll Cardiol. 2007 Mar 27;49(12):1251-64.

16126.  Avis NE, Pian-Smith MC. Acupuncture for hot flashes. Menopause. 2007 Jan-Feb;14(1):10-3.

16127.  Bamigboye AA, Smyth R.  Interventions for varicose veins and leg oedema in pregnancy. Cochrane Database Syst Rev. 2007 Jan 24;(1):CD001066. Review. 

16128.  Bhardwaj KR, Gulia R, Yadav OP. Biodiversity conservation strategies for medicinal and aromatic plants: an appraisal of present status and development needs. Eco Res J Bio Sci 2006, 5(1), 83-93.

16129.  Bharathi K, Gopakumar K. Vaginal douching with Karanjakvatha in non specific leucorrhoea �A clinical evaluation. Aryavaidyan 2007, 20(3), 167-171.

16130.  Bhimani S. Clinical study of efficacy of glycoban cap in patients of non- insulin dependent  diabetes (NIDDM) mellitus.  Antiseptic. 2005 Feb; 102(2): 71-75.

16131.  Block KI.  The demise of the super-aspirins: an opportunity for integrative medicine? Integr Cancer Ther. 2005 Mar;4(1):5-7. 

16132.  Boak L, Chin-Dusting JP.  Hypercholesterolemia and endothelium dysfunction: role of dietary supplementation as vascular protective agents. Curr Vasc Pharmacol. 2004 Jan;2(1):45-52. Review. 

16133.  Boon HS, Olatunde F, Zick SM.  Trends in complementary/alternative medicine use by breast cancer survivors: comparing survey data from 1998 and 2005. BMC Womens Health. 2007 Mar 30;7:4. 

16134.  Brandin H, Viitanen E, Myrberg O, Arvidsson AK.  Effects of herbal medicinal products and food supplements on induction of CYP1A2, CYP3A4 and MDR1 in the human colon carcinoma cell line LS180. Phytother Res. 2007 Mar;21(3):239-44. 

16135.  Brimblecombe N, Tingle A, Tunmore R, Murrells T.  Implementing holistic practices in mental health nursing: a national  consultation. Int J Nurs Stud. 2007 Mar;44(3):339-48.

16136.  Brown KH, de Romana DL, Arsenault JE, Peerson JM, Penny ME.  Comparison of the effects of zinc delivered in a fortified food or a liquid supplement on the growth, morbidity, and plasma zinc concentrations of young Peruvian children. Am J Clin Nutr. 2007 Feb;85(2):538-47. 

16137.  Bull L.  Sunflower therapy for children with specific learning difficulties (dyslexia): a randomised, controlled trial. Complement Ther Clin Pract. 2007 Feb;13(1):15-24. 

16138.  Cameron LD, Booth RJ, Schlatter M, Ziginskas D, Harman JE.  Changes in emotion regulation and psychological adjustment following use of a group psychosocial support program for women recently diagnosed with breast cancer. Psychooncology. 2007 Mar;16(3):171-80. 

16139.  Chao AS, Chao A, Wang TH, Chang YC, Peng HH, Chang SD, Chao A, Chang CJ, Lai CH, Wong AM.  Pain relief by applying transcutaneous electrical nerve stimulation (TENS) on acupuncture points during the first stage of labor: a randomized double-blind placebo-controlled trial. Pain. 2007 Feb;127(3):214-20.

16140.  Chen S, Lv F, Gao J, Lin J, Liu Z, Fu Y, Liu Y, Lin B, Xie Y, Ren X, Xu Y, Fan X, Xu A.   HLA class II polymorphisms associated with the physiologic characteristics defined by Traditional Chinese Medicine: linking modern genetics with an ancient medicine. J Altern Complement Med. 2007 Mar;13(2):231-9. 

16141.  Chima CS.  Diet manuals to practice manuals: the evolution of nutrition care. Nutr Clin Pract. 2007 Feb;22(1):89-100. Review. 

16142.  Chaterji R, Tractenberg RE, Amri H, Lumpkin M, Amorosi SB, Haramati A.  A large-sample survey of first- and second-year medical student attitudes toward complementary and alternative medicine in the curriculum and in practice. Altern Ther Health Med. 2007 Jan-Feb;13(1):30-5. 

16143.  Cohen BE, Kanaya AM, Macer JL, Shen H, Chang AA, Grady D.  Feasibility and acceptability of restorative yoga for treatment of hot flushes: a pilot trial. Maturitas. 2007 Feb 20;56(2):198-204.

16144.  Collins C.  Said another way: stroke, evolution, and the rainforests: an ancient approach to modern health care. Nurs Forum. 2007 Jan-Mar;42(1):39-44. 

16145.  Colbin A. "Whole food" supplements? Altern Ther Health Med. 2007 Jan-Feb;13(1):12. 

16146.  Colquhoun D. Treating critically ill patients with sugar pills. Chest. 2007 Feb;131(2):635-6; author reply 636.

16147.  Cuellar NG, Rogers AE, Hisghman V.  Evidenced based research of complementary and alternative medicine (CAM) for sleep in the community dwelling older adult. Geriatr Nurs. 2007 Jan-Feb;28(1):46-52; quiz 53.

16148.  Davis JM, Fleming MF, Bonus KA, Baker TB.  A pilot study on mindfulness based stress reduction for smokers. BMC Complement Altern Med. 2007 Jan 25;7:2.

16149.  Decker C, Huddleston J, Kosiborod M, Buchanan DM, Stoner C, Jones A, Banerjee S, Spertus JA.  Self-reported use of complementary and alternative medicine in patients with previous acute coronary syndrome. Am J Cardiol. 2007 Apr 1;99(7):930-3.

16150.  Dickel ML, Rates SM, Ritter MR.  Plants popularly used for loosing weight purposes in Porto Alegre, South Brazil. J Ethnopharmacol. 2007 Jan 3;109(1):60-71.

16151.  Dietert RR, Dietert JM.  Early-life immune insult and developmental immunotoxicity (DIT)-associated diseases: potential of herbal- and fungal-derived medicinals. Curr Med Chem. 2007;14(10):1075-85. Review. 

16152.  Eisenberg DM, Post DE, Davis RB, Connelly MT, Legedza AT, Hrbek AL, Prosser LA, Buring JE, Inui TS, Cherkin DC.  Addition of choice of complementary therapies to usual care for acute low back pain: a randomized controlled trial. Spine. 2007 Jan 15;32(2):151-8. 

16153.  Elder C, Ritenbaugh C, Mist S, Aickin M, Schneider J, Zwickey H, Elmer P.   Randomized trial of two mind-body interventions for weight-loss maintenance. J Altern Complement Med. 2007 Jan-Feb;13(1):67-78.

16154.  Ezzo J.  What can be learned from Cochrane systematic reviews of massage that can guide future research? J Altern Complement Med. 2007 Mar;13(2):291-5. Review.

16155.  Felson DT, Lawrence RC, Dieppe PA, Hirsch R, Helmick CG, Jordan JM, Kington RS, Lane NE, Nevitt MC, Zhang Y, Sowers M, McAlindon T, Spector TD, Poole AR, Yanovski SZ, Ateshian G, Sharma L, Buckwalter JA, Brandt KD, Fries JF.   Osteoarthritis: new insights. Part 1: the disease and its risk factors. Ann Intern Med. 2000 Oct 17;133(8):635-46. Review. 

16156.  Figueroa-Moseley C, Jean-Pierre P, Roscoe JA, Ryan JL, Kohli S, Palesh OG, Ryan EP, Carroll J, Morrow GR.  Behavioral interventions in treating anticipatory nausea and vomiting. J Natl Compr Canc Netw. 2007 Jan;5(1):44-50. Review.

16157.  Fisher MA.  Medicine and industry: a necessary but conflicted relationship. Perspect Biol Med. 2007 Winter;50(1):1-6. 

16158.  Garland B.  Patient's page: weight loss and herbal supplements. South Med J. 2007 Jan;100(1):89.

16159.  Gagnier JJ, van Tulder MW, Berman B, Bombardier C.  Herbal medicine for low back pain: a Cochrane review. Spine. 2007 Jan 1;32(1):82-92. Review. 

16160.  Geffen JR.  From integrative to multidimensional medicine. Altern Ther Health Med. 2007 Jan-Feb;13(1):14-8. Review.

16161.  Giugliano D.  Dietary antioxidants for cardiovascular prevention. Nutr Metab Cardiovasc Dis. 2000 Feb;10(1):38-44. Review. 

16162.  Goldberg RJ, Katz J. A meta-analysis of the analgesic effects of omega-3 polyunsaturated fatty acid supplementation for inflammatory joint pain. Pain. 2007 May;129(1-2):210-23.

16163.  Gopakumar K; Bharathi K. Clinical study in "nishamalaki churna" in Ikshumedha (Diabetes Mellitus).  Antiseptic. 2005 May- Supplement; 102(5): 270-272.

16164.  Hadapad BS. Non malignant nodule treated with Ayurveda - A case report. Aryavaidyan 2007, 20(4), 221-222.

16165.  Haidvogl M, Riley DS, Heger M, Brien S, Jong M, Fischer M, Lewith GT, Jansen G, Thurneysen AE.  Homeopathic and conventional treatment for acute respiratory and ear complaints: a comparativee study on outcome in the primary care setting. BMC Complement Altern Med. 2007 Mar 2;7:7.

16166.  Henry SG, Zaner RM, Dittus RS.  Viewpoint: Moving beyond evidence-based medicine. Acad Med. 2007 Mar;82(3):292-7. 

16167.  Hillier D, Caan W, McVicar A.  Research training and leadership for midwives and health visitors. Community Pract. 2007 Jan;80(1):28-33. 

16168.  Hirschkorn KA, Bourgeault IL.  Actions speak louder than words: mainstream health providers' definitions and behaviour regarding complementary and alternative medicine. Complement Ther Clin Pract. 2007 Feb;13(1):29-37.

16169.  Hlubocky FJ, Ratain MJ, Wen M, Daugherty CK. Complementary and alternative medicine among advanced cancer patients enrolled on phase I trials: a study of prognosis, quality of life, and preferences for decision making. J Clin Oncol. 2007 Feb 10;25(5):548-54.

16170.  Horrigan BJ.  Consciousness at work: recent research points to the power of our thoughts and intentions. Explore (NY). 2007 Jan-Feb;3(1):6-7.

16171.  Hsu CH, Liao YL, Lin SC, Hwang KC, Chou P.  The mushroom Agaricus Blazei Murill in combination with metformin and gliclazide improves insulin resistance in type 2 diabetes: a randomized, double-blinded, and placebo-controlled clinical trial. J Altern Complement Med. 2007 Jan-Feb;13(1):97-102.

16172.  Hunton M.  Patient compliance. Homeopathy. 2007 Jan;96(1):68.

16173.  Ismail HM.  The role of omega-3 fatty acids in cardiac protection: an overview. Front Biosci. 2005 May 1;10:1079-88. Review. 

16174.  Jain P. Alternative therapies and warfarin . Heart Matter 2006, 17(1), 17-20.

16175.  Jatoi A, Burch P, Hillman D, Vanyo JM, Dakhil S, Nikcevich D, Rowland K, Morton R, Flynn PJ, Young C, Tan W; North Central Cancer Treatment Group.  A tomato-based, lycopene-containing intervention for androgen-independent prostate cancer: results of a Phase II study from the North Central Cancer Treatment Group. Urology. 2007 Feb;69(2):289-94. 

16176.  Johnston MF, Yang C, Hui KK, Xiao B, Li XS, Rusiewicz A.  Acupuncture for chemotherapy-associated cognitive dysfunction: a hypothesis-generating literature review to inform clinical advice. Integr Cancer Ther. 2007 Mar;6(1):36-41. Review. 

16177.  Jones TH, Hanney S, Buxton MJ.  The information sources and journals consulted or read by UK paediatricians to inform their clinical practice and those which they consider important: a questionnaire survey. BMC Pediatr. 2007 Jan 15;7:1. 

16178.  Joyal SV.   A perspective on the current strategies for the treatment of obesity. Curr Drug Targets CNS Neurol Disord. 2004 Oct;3(5):341-56. Review. 

16179.  Kamatenesi-Mugisha M, Oryem-Origa H.  Medicinal plants used to induce labour during childbirth in western Uganda. J Ethnopharmacol. 2007 Jan 3;109(1):1-9.

16180.  Katz P, Lee F.  Racial/ethnic differences in the use of complementary and alternative medicine in patients with arthritis. J Clin Rheumatol. 2007 Feb;13(1):3-11. 

16181.  Kemper KJ.  The yin and yang of integrative clinical care, education, and research. Explore (NY). 2007 Jan-Feb;3(1):37-41. Review. 

16182.  Kligler B.  Patient empowerment: taking integrative medicine to the next level. J Altern Complement Med. 2007 Mar;13(2):189-90.

16183.  Klimenko E, Julliard K.  Communication between CAM and mainstream medicine: Delphi panel perspectives. Complement Ther Clin Pract. 2007 Feb;13(1):46-52.

16184.  Kolodziej H, Kiderlen AF.  In vitro evaluation of antibacterial and immunomodulatory activities of Pelargonium reniforme, Pelargonium sidoides and the related herbal drug preparation EPs 7630. Phytomedicine. 2007;14 Suppl 6:18-26.

16185.  Kune R, Kune G.  Mainstream medicine versus complementary and alternative medicine in the witness box: resolving the clash of ideologies. J Law Med. 2007 Feb;14(3):425-32

16186.  Kunz S, Schulz M, Lewitzky M, Driessen M, Rau H.  Ear acupuncture for alcohol withdrawal in comparison with aromatherapy: a randomized-controlled trial. Alcohol Clin Exp Res. 2007 Mar;31(3):436-42. 

16187.  Lai YL, Chan CW, Lopez V.  Perceptions of dyspnea and helpful interventions during the advanced stage of lung cancer: Chinese patients' perspectives. Cancer Nurs. 2007 Mar-Apr;30(2):E1-8. 

16188.  Lao CD, Brenner DE.  Strategies for prevention of colorectal cancer: pharmaceutical and nutritional interventions. Curr Treat Options Oncol. 2004 Oct;5(5):417-26. Review.

16189.  Lane JD, Seskevich JE, Pieper CF.  Brief meditation training can improve perceived stress and negative mood. Altern Ther Health Med. 2007 Jan-Feb;13(1):38-44. 

16190.  Langevin HM, Sherman KJ.  Pathophysiological model for chronic low back pain integrating connective tissue and nervous system mechanisms. Med Hypotheses. 2007;68(1):74-80.

16191.  Lee SH, Ahn SC, Lee YJ, Choi TK, Yook KH, Suh SY.  Effectiveness of a meditation-based stress management program as an adjunct to pharmacotherapy in patients with anxiety disorder. J Psychosom Res. 2007 Feb;62(2):189-95.   

16192.  Leo RJ, Ligot JS Jr.  A systematic review of randomized controlled trials of acupuncture in the treatment of depression. J Affect Disord. 2007 Jan;97(1-3):13-22.

16193.  Lesser D, Hillesheim P.  Pancreatitis in a woman taking an herbal supplement. South Med J. 2007 Jan;100(1):59-60. 

16194.  Li B, Wang Z, Fang JJ, Xu CY, Chen WX.  Evaluation of prognostic markers in severe drug-induced liver disease. World J Gastroenterol. 2007 Jan 28;13(4):628-32. 

16195.  Loppie C.  Learning from the grandmothers: incorporating indigenous principles into qualitative research. Qual Health Res. 2007 Feb;17(2):276-84. 

16196.  Malik VS, Hu FB.   Popular weight-loss diets: from evidence to practice. Nat Clin Pract Cardiovasc Med. 2007 Jan;4(1):34-41. 

16197.  Mangal A, Panda D, Sharma MC. Peptic ulcer healing properties of Shatavari (Asparagus racemosus Willd.). Indian J Tradl Knowledge 2006, 5(2), 227-8.

16198.  Mao JJ, Farrar JT, Xie SX, Bowman MA, Armstrong K.  Use of complementary and alternative medicine and prayer among a national sample of cancer survivors compared to other populations without cancer. Complement Ther Med. 2007 Mar;15(1):21-9.

16199.  Martinez Devesa P, Waddell A, Perera R, Theodoulou M.  Cognitive behavioural therapy for tinnitus. Cochrane Database Syst Rev. 2007 Jan 24;(1):CD005233. Review. 

16200.  Mastrangelo D.  Hormesis, epitaxy, the structure of liquid water, and the science of homeopathy. Med Sci Monit. 2007 Jan;13(1):SR1-8.

16201.  Mastrangelo MA, Galantino ML, House L.  Effects of yoga on quality of life and flexibility in menopausal women: a case series. Explore (NY). 2007 Jan-Feb;3(1):42-5.

16202.  McClaskey EM, Michalets EL.  Subdural hematoma after a fall in an elderly patient taking high-dose omega-3 fatty acids with warfarin and aspirin: case report and review of  the literature. Pharmacotherapy. 2007 Jan;27(1):152-60. 

16203.  Mehling WE, Jacobs B, Acree M, Wilson L, Bostrom A, West J, Acquah J, Burns B, Chapman J, Hecht FM.  Symptom management with massage and acupuncture in postoperative cancer  patients: a randomized controlled trial. J Pain Symptom Manage. 2007 Mar;33(3):258-66. 

16204.  Michaud LB, Karpinski JP, Jones KL, Espirito J.  Dietary supplements in patients with cancer: risks and key concepts, part 2. Am J Health Syst Pharm. 2007 Mar 1;64(5):467-80. Review. 

16205.  Michaud LB, Karpinski JP, Jones KL, Espirito J.  Dietary supplements in patients with cancer: risks and key concepts, part 1. Am J Health Syst Pharm. 2007 Feb 15;64(4):369-81. Review. 

16206.  Molassiotis A, Helin AM, Dabbour R, Hummerston S.  The effects of P6 acupressure in the prophylaxis of chemotherapy-related nausea and vomiting in breast cancer patients. Complement Ther Med. 2007 Mar;15(1):3-12.

16207.  Muramatsu S. Acupuncture and knee osteoarthritis. Ann Intern Med. 2007 Jan 16;146(2):147; author reply 148-9.

16208.  Mulholland CA, Benford DJ.  What is known about the safety of multivitamin-multimineral supplements for the generally healthy population? Theoretical basis for harm. Am J Clin Nutr. 2007 Jan;85(1):318S-322S. Review. 

16209.  Mutter J, Naumann J, Guethlin C.  Elimination of xenobiotics in a female patient with fibromyalgia, chronic fatigue, and trunk obesity. Forsch Komplementarmed. 2007 Feb;14(1):39-44.

16210.  Myers CD.  Complementary and alternative medicine for persistent facial pain. Dent Clin North Am. 2007 Jan;51(1):263-74, ix. Review. 

16211.  Murphy SP, White KK, Park SY, Sharma S.  Multivitamin-multimineral supplements' effect on total nutrient intake. Am J Clin Nutr. 2007 Jan;85(1):280S-284S. Review. 

16212.  Neri I, De Pace V, Venturini P, Facchinetti F.  Effects of three different stimulations (acupuncture, moxibustion, acupuncture plus moxibustion) of BL.67 acupoint at small toe on fetal behavior of breech presentation. Am J Chin Med. 2007;35(1):27-33. 

16213.  Nitalikar MM, Gaikwad DD, Throat RM, Ambre SD. Tulsi: elixir of life Antiseptic. 2005 May-Supplement; 102(5): 265-267.

16214.  Pal MN. Health through self-regulation - an insight through ayurveda. Aryavaidyan 2005, 19(2), 115-21.

16215.  Paolino A. Validity of Chinese herbal medicine called into question. Lancet Oncol. 2007 Mar;8(3):196.

16216.  Park C, So HS, Shin SH, Choi JY, Lee I, Kim JK, Chung SY, Park R.  The water extract of Omija protects H9c2 cardiomyoblast cells from hydrogen peroxide through prevention of mitochondrial dysfunction and activation of caspases pathway. Phytother Res. 2007 Jan;21(1):81-8.

16217.  Patankar U, Sharma SS. Application of leech in buerger's disease. Aryavaidyan 2005, 19(2), 81-5.

16218.  Pearce C, Curtis M.  A multidisciplinary approach to self care in chronic pelvic pain. Br J Nurs. 2007 Jan 25-Feb 7;16(2):82-5. 

16219.  Pearson TA, Osorio D, Brown K.  Nutritional interventions in cardiovascular disease: new challenges and opportunities. Curr Atheroscler Rep. 2000 Nov;2(6):515-20. Review. 

16220.  Pembrey S. Holistic treatment of breast cancer  Health Administrator. 2005 Jul; 17(1): 218-220.

16221.  Pippa L, Manzoli L, Corti I, Congedo G, Romanazzi L, Parruti G.  Functional capacity after traditional Chinese medicine (qi gong) training in patients with chronic atrial fibrillation: a randomized controlled trial. Prev Cardiol. 2007 Winter;10(1):22-5. 

16222.  Piirainen T, Laitinen K, Isolauri E.  Impact of national fortification of fluid milks and margarines with vitamin D on dietary intake and serum 25-hydroxyvitamin D concentration in 4-year-old children. Eur J Clin Nutr. 2007 Jan;61(1):123-8.

16223.  Poddar A, Vadlamudi VP, Koley KM, Dewangan G. Anti-inflammatory acitivity of Calotopis gigantean leaves. Aryavaidyan 2007, 20(3), 178-180.

16224.  Porrata H, Porrata A, Sosner J.  New carpal ligament traction device for the treatment of carpal tunnel syndrome unresponsive to conservative therapy. J Hand Ther. 2007 Jan-Mar;20(1):20-7; quiz 28. 

16225.  Pukall C, Kandyba K, Amsel R, Khalife S, Binik Y.  Effectiveness of hypnosis for the treatment of vulvar vestibulitis syndrome: a preliminary investigation. J Sex Med. 2007 Mar;4(2):417-25. 

16226.  Quimby EL.  The use of herbal therapies in pediatric oncology patients: treating symptoms of cancer and side effects of standard therapies. J Pediatr Oncol Nurs. 2007 Jan-Feb;24(1):35-40.

16227.  Rao MM, Kar AC, Bhattacharya P, Hazra J. Ayurvedic management of Fissure-in-ano. Aryavaidyan 2007, 20(4), 210-215.

16228.  Reginster JY, Gillot V, Bruyere O, Henrotin Y. Evidence of nutriceutical effectiveness in the treatment of osteoarthritis. Curr Rheumatol Rep. 2000 Dec;2(6):472-7. Review. 

16229.  Rejler M, Spangeus A, Tholstrup J, Andersson-Gare B.  Improved population-based care: Implementing patient-and demand-directed care for inflammatory bowel disease and evaluating the redesign with a population-based registry. Qual Manag Health Care. 2007 Jan-Mar;16(1):38-50.

16230.  Rohde J.  Starvation and diet according to the Vinzenz Priessnitz family water book of 1847. Forsch Komplementarmed. 2007 Feb;14(1):33-8.

16231.  Ryan MA, Smith TC, Smith B, Amoroso P, Boyko EJ, Gray GC, Gackstetter GD, Riddle JR, Wells TS, Gumbs G, Corbeil TE, Hooper TI.  Millennium Cohort: enrollment begins a 21-year contribution to understanding the impact of military service. J Clin Epidemiol. 2007 Feb;60(2):181-91.

16232.  Sareen S, Kumari V, Gajebasia KS, Gajebasia NK.  Yoga: a tool for improving the quality of life in chronic pancreatitis. World J Gastroenterol. 2007 Jan 21;13(3):391-7. 

16233.  Scheid V. Traditional Chinese medicine--what are we investigating? The case of menopause. Complement Ther Med. 2007 Mar;15(1):54-68.

16234.  Schanler RJ.  Evaluation of the evidence to support current recommendations to meet the needs of premature infants: the role of human milk. Am J Clin Nutr. 2007 Feb;85(2):625S-628S. 

16235.  Seely D, Stempak D, Baruchel S.  A strategy for controlling potential interactions between natural health products and chemotherapy: a review in pediatric oncology. J Pediatr Hematol Oncol. 2007 Jan;29(1):32-47. Review. 

16236.  Seo J, Lee HS, Ha E, Park HJ, Park HK, Lee H, Kang S, Yin C, Kim J, Leem KH, Kim EH, Ryu Y, Choi S, Chung JH. Efficacy of combined treatment by scalp and penetration  acupunctures with TKM medication (tang) on stroke patients. Neurol Res. 2007;29 Suppl 1:S38-41. 

16237.  Sengar M; Bhutani M; Aggarwal D; Kochupillai V. Cancer treatment: role of yoga, naturopathy and prayer Health Administrator. 2005 Jul; 17(1): 151-157.

16238.  Sephton SE, Salmon P, Weissbecker I, Ulmer C, Floyd A, Hoover K, Studts JL.   Mindfulness meditation alleviates depressive symptoms in women with fibromyalgia: results of a randomized clinical trial. Arthritis Rheum. 2007 Feb 15;57(1):77-85. 

16239.  Shin BC, Lee MS.  Effects of aromatherapy acupressure on hemiplegic shoulder pain and motor power in stroke patients: a pilot study. J Altern Complement Med. 2007 Mar;13(2):247-51. 

16240.  Shinozuka N, Tatsumi K, Nakamura A, Terada J, Kuriyama T.  The traditional herbal medicine Hochuekkito improves systemic inflammation in patients with chronic obstructive pulmonary disease. J Am Geriatr Soc. 2007 Feb;55(2):313-4. 

16241.  Shukla Y, Kalra N.   Cancer chemoprevention with garlic and its constituents. Cancer Lett. 2007 Mar 18;247(2):167-81.

16242.  Sierpina VS, Sierpina M, Loera JA, Grumbles L.  Complementary and integrative approaches to dementia. South Med J. 2005 Jun;98(6):636-45. Review. Summary for patients in: South Med J. 2005 Jun;98(6):677. 

16243.  Silverman J.  Mindfulness meditation and public health. Conn Med. 2007 Jan 71(1):35.

16244.  Sipponen A, Jokinen JJ, Lohi J.  Resin salve from the Norwegian spruce tree: a 'novel' method for the treatment of chronic wounds. J Wound Care. 2007 Feb;16(2):72-4. Review.

16245.  Staples JK, Wilson AT, Pierce B, Gordon JS.  Effectiveness of CancerGuides a study of an integrative cancer care training program for health professionals. Integr Cancer Ther. 2007 Mar;6(1):14-24. 

16246.  Stockert K, Schneider B, Porenta G, Rath R, Nissel H, Eichler I.  Laser acupuncture and probiotics in school age children with asthma: a randomized, placebo-controlled pilot study of therapy guided by principles of Traditional Chinese Medicine. Pediatr Allergy Immunol. 2007 Mar;18(2):160-6.   

16247.  Suen LK, Wong TK, Chung JW, Yip VY.  Auriculotherapy on low back pain in the elderly. Complement Ther Clin Pract. 2007 Feb;13(1):63-9.

16248.  Tsang KL, Carlson LE, Olson K.  Pilot crossover trial of Reiki versus rest for treating  cancer-related fatigue. Integr Cancer Ther. 2007 Mar;6(1):25-35. 

16249.  Tang YL, Sevigny R, Mao PX, Jiang F, Cai Z.  Help-seeking behaviors of Chinese patients with schizophrenia admitted to a psychiatric hospital. Adm Policy Ment Health. 2007 Mar;34(2):101-7. 

16250.  Tambekar DH, Saratkar KR. Antibacterial properties of traditionally used medicinal plant for enteric infection by adivasi (Bumaka) in Melghat of Amravati district. Asian J Microbiol Biotechnol envir Sci 2005, 7(4), 873-8.

16251.  Taylor CL.  Highlights of 'a model for establishing upper levels of intake for nutrients and related substances: report of a Joint FAO/WHO Technical Workshop on Nutrient Risk Assessment, May 2-6, 2005'. Nutr Rev. 2007 Jan;65(1):31-8. Review. 

16252.  Thachil AF, Mohan R, Bhugra D.  The evidence base of complementary and alternative therapies in depression. J Affect Disord. 2007 Jan;97(1-3):23-35.

16253.  Tharakan ST, Kuttan G, Kuttan R. Effect of AC II, a herbal formulation on radiation-induced immunosuppression in mice. Indian J expl Biol 2006, 44(9), 719-25.

16254.  Tian H, Ip L, Luo H, Chang DC, Luo KQ.  A high throughput drug screen based on fluorescence resonance energy transfer (FRET) for anticancer activity of compounds from herbal medicine. Br J Pharmacol. 2007 Feb;150(3):321-34.

16255.  Tong X, Zheng S, Jin J, Zhu L, Lou Y, Yao H.  Triptolide inhibits cyclooxygenase-2 and inducible nitric oxide synthase expression in human colon cancer and leukemia cells. Acta Biochim Biophys Sin (Shanghai). 20 07 Feb;39(2):89-95.

16256.  Uma C, Sasikumar JM. Antimicrobial activity of traditional medicinal plants from southern western ghats. Asian J Microbiol Biotechnol envir Sci 2005, 7(4), 665-70.

16257.  Ventegodt S, Thegler S, Andreasen T, Struve F, Enevoldsen L, Bassaine L, Torp M, Merrick J.  Clinical holistic medicine (mindful, short-term psychodynamic psychotherapy complemented with bodywork) in the treatment of experienced mental illness. ScientificWorldJournal. 2007 Mar 2;7:306-9. 

16258.  Von Riedenauer WB, Baker MK, Brewer RJ.  Video-assisted thorascopic removal of migratory acupuncture needle causing  pneumothorax. Chest. 2007 Mar;131(3):899-901.

16259.  Vos C, Verhagen A, Passchier J, Koes B.  Management of acute neck pain in general practice: a prospective study. Br J Gen Pract. 2007 Jan;57(534):23-8. 

16260.  Wang C, Xiong Z, Deng C, Yu W, Ma W.  Miniscalpel-needle versus triggerpoint injection for cervical myofascial pain syndrome: a randomized comparative trial. J Altern Complement Med. 2007 Jan-Feb;13(1):14-6.

16261.  Weidenhammer W, Linde K, Streng A, Hoppe A, Melchart D.  Acupuncture for chronic low back pain in routine care: a multicenter observational study. Clin J Pain. 2007 Feb;23(2):128-35. 

16262.  Wojcicki JM, Kankasa C, Mitchell C, Wood C.  Traditional practices and exposure to bodily fluids in Lusaka, Zambia. Trop Med Int Health. 2007 Jan;12(1):150-5. 

16263.  Wojcikowski K, Stevenson L, Leach D, Wohlmuth H, Gobe G.  Antioxidant capacity of 55 medicinal herbs traditionally used to treat the urinary system: a comparison using a sequential three-solvent extraction process. J Altern Complement Med. 2007 Jan-Feb;13(1):103-9. 

16264.  Wong JS, Ong TA, Chua HH, Tan C.  Acute anuric renal failure following jering bean ingestion. Asian J Surg. 2007 Jan;30(1):80-1.  

16265.  Wright KD, Stewart SH, Finley GA, Buffett-Jerrott SE.  Prevention and intervention strategies to alleviate preoperative anxiety in children: a critical review. Behav Modif. 2007 Jan;31(1):52-79. Review.

16266.  Wu HS, Lin LC, Wu SC, Lin JG.  The psychologic consequences of chronic dyspnea in chronic pulmonary  obstruction disease: the effects of acupressure on depression. J Altern Complement Med. 2007 Mar;13(2):253-61.

16267.  Wu P, Fuller C, Liu X, Lee HC, Fan B, Hoven CW, Mandell D, Wade C, Kronenberg F.   Use of complementary and alternative medicine among women with depression: results of a national survey. Psychiatr Serv. 2007 Mar;58(3):349-56. 

16268.  Yadav AK, Yadav S, Tripathi JS. Genetics concepts in Ayurveda. Aryavaidyan 2007, 20(4), 232-234.

16269.  Yang H, Shi G, Dou QP.  The tumor proteasome is a primary target for the natural anticancer compound Withaferin A isolated from "Indian winter cherry". Mol Pharmacol. 2007 Feb;71(2):426-37.

16270.  Yin XX, Chen ZQ, Liu ZJ, Ma QJ, Dang GT.  Icariine stimulates proliferation and differentiation of human osteoblasts by increasing production of bone morphogenetic protein 2. Chin Med J (Engl). 2007 Feb 5;120(3):204-10.  

16271.  Zhang XP, Liu DR, Shi Y.  Study progress in therapeutic effects of traditional Chinese medicine monomer in severe acute pancreatitis. J Zhejiang Univ Sci B. 2007 Feb;8(2):147-52. Review. 

 

 

Back

October 2007

Some Selected abstracts:

1.            Ben-Arye E, Lear A, Hermoni D, Margalit RS. Promoting lifestyle self-awareness among the medical team by the use of an integrated teaching approach: a primary care experience.  J Altern Complement Med. 2007 May;13(4):461-9. 

The Complementary and Traditional Medicine Unit, Department of Family Medicine, Clalit Health Services, Haifa and Western Galilee District, Technion-Israel Institute of Technology, Haifa, Israel. eranben@netvision.net.il

OBJECTIVES: Healthy lifestyle is recommended in clinical guidelines for the prevention and treatment of chronic diseases such as cardiovascular disease and diabetes. Research previously identified a gap between lifestyle recommendations and their implementation in clinical practice. In this paper, we describe a pilot educational program aimed to promote providers' awareness of their own lifestyles, and to explore whether increased personal awareness enhances providers' willingness to engage in lifestyle-change discussion with patients. METHODS: Two primary-care urban clinics in Northern Israel participated in the program, which consisted of a series of six biweekly educational sessions, each lasting 2-4 hours. Each session included both knowledge-based and experiential learning based on complementary medicine modalities. Surveys at the end of the program and a year later provided the program evaluation. RESULTS: Thirty-five personnel participated in the program. Thirteen (13) of the 20 participants (65%) reported an attitude change regarding eating habits after the program. At 1-year follow up, 24 of the 27 respondents (89%) stated that they were more aware of their eating habits and of their physical activity compared with precourse status. Twenty-three (23) of 27 respondents (85%) stated that after the program they were better prepared to initiate a conversation with their patients about lifestyle change. CONCLUSIONS: An integrated educational approach based on knowledge-based and complementary and alternative medicine experiential modalities, aimed to facilitate self-awareness, may enhance learners' attitude change. The findings demonstrate readiness of learners to reexamine their lifestyles. Increased self-awareness helped participants to make a positive attitude change regarding eating habits and physical activity and was associated with participants' increased engagement in lifestyle-change discussions with patients. The teaching approach had longstanding effect, noted in the one-year follow-up.

2.            Bonomi P.  Paclitaxel poliglumex (PPX, CT-2103): macromolecular medicine for  advanced non-small-cell lung cancer. Expert Rev Anticancer Ther. 2007 Apr;7(4):415-22. Review. 

Taxanes, including paclitaxel and docetaxel, are widely used cytotoxic agents for the treatment of solid tumors. Paclitaxel, a small, hydrophobic agent, binds extensively to plasma proteins, and its pharmacokinetic profile is characterized by a short plasma elimination half-life with a broad tissue distribution. These unfavorable pharmacokinetic characteristics are associated with limited tumor exposure and high systemic exposure, reducing the therapeutic index of paclitaxel. Paclitaxel poliglumex (PPX, CT-2103), a polymer-drug conjugate of paclitaxel and poly-L-glutamic acid, was designed to enhance the therapeutic index of paclitaxel by improving its pharmacokinetic profile, and to provide a water-soluble alternative to the standard paclitaxel formulation. Potential advantages of polymer-drug conjugates include delivery of a higher concentration of active drug to tumor tissue and limited exposure of normal tissues. In addition, the slow release of drug from the polymer carrier lowers peak plasma concentrations of the active drug.

3.            John PJ, Sharma N, Sharma CM, Kankane A.  Effectiveness of yoga therapy in the treatment of migraine without aura: a randomized controlled trial. Headache. 2007 May;47(5):654-61. 

Department of Zoology, University of Rajasthan, Jaipur, Rajasthan, India.

BACKGROUND: Numerous studies have explored the effectiveness of complementary and alternative medicine in the treatment of migraine but there is no documented investigation of the effectiveness of yoga therapy for migraine management. OBJECTIVES: To investigate the effectiveness of holistic approach of yoga therapy for migraine treatment compared to self-care. DESIGN: A randomized controlled trial. METHODS: Seventy-two patients with migraine without aura were randomly assigned to yoga therapy or self-care group for 3 months. Primary outcomes were headache frequency (headache diary), severity of migraine (0-10 numerical scale) and pain component (McGill pain questionnaire). Secondary outcomes were anxiety and depression (Hospital anxiety depression scale), medication score. RESULTS: After adjustment for baseline values, the subjects' complaints related to headache intensity (P < .001), frequency (P < .001), pain rating index (P < .001), affective pain rating index (P < .001), total pain rating index (P < .001), anxiety and depression scores (P < .001), symptomatic medication use (P < .001) were significantly lower in the yoga group compared to the self-care group. CONCLUSION: The study demonstrated a significant reduction in migraine headache frequency and associated clinical features, in patients treated with yoga over a period of 3 months. Further study of this therapeutic intervention appears to be warranted.

4.            Nutescu EA. Assessing, preventing, and treating venous thromboembolism: evidence-based approaches. Am J Health Syst Pharm. 2007 Jun 1;64(11 Suppl 7):S5-13. Review. 

University of Illinois at Chicago, Department of Pharmacy Practice, Chicago, IL 60612, USA. enutescu@uic.edu

PURPOSE: The long-term complications of deep vein thrombosis (DVT), assessment of risk for venous thromboembolism (VTE) in medical and surgical patients, recommendations in evidence-based guidelines for VTE prophylaxis in surgical and medical patients and the treatment of VTE, and a new alternative for VTE prophylaxis and treatment are discussed. SUMMARY: Pulmonary embolism (PE) is an acute complication of DVT, and recurrent DVT, post-thrombotic syndrome, and death are long-term complications of DVT. The need to assess VTE risk and provide VTE prophylaxis are well recognized in surgical patients. However, VTE prophylaxis is underutilized in medical patients despite the fact that DVT is common and guidelines for prophylaxis are available, partly because the condition often is asymptomatic in these patients. The risk for VTE increases as the number of risk factors increases, so the aggressiveness of VTE prophylaxis in medical and surgical patients increases as the risk of VTE increases. The most recent American College of Chest Physicians (ACCP) guidelines recommend low-dose unfractionated heparin or low-molecular-weight heparin (LMWH) for VTE prophylaxis in acutely ill medical patients. The treatment of VTE recommended by ACCP involves short-term LMWH or unfractionated heparin therapy plus long-term oral warfarin therapy. The pentasaccharide, factor Xa inhibitor, fondaparinux is a new alternative for VTE prophylaxis and treatment. Reducing LMWH doses for patients with severe renal impairment may offer a safety advantage. Fixed doses of LMWH are customarily used for VTE prophylaxis regardless of body weight or body mass index, but weight-based dosing with larger doses for obese patients may be more effective than fixed doses. CONCLUSION: Efforts to assess VTE risk and apply evidence-based guidelines for VTE prophylaxis and treatment in medical patients as well as surgical patients can improve patient care and outcomes. Findings from recent clinical research provide clinicians with clarification about the optimal prophylactic and treatment strategies, and future guidelines will reflect these findings.

5.             Shukla Y, Singh M.  Cancer preventive properties of ginger: a brief review. Food Chem Toxicol. 2007 May;45(5):683-90.

Environmental Carcinogenesis Division, Industrial Toxicology Research Centre, P.O. Box 80, M.G. Marg, Lucknow 226 001, Uttar Pradesh, India. yogeshwer_shukla@hotmail.com <yogeshwer_shukla@hotmail.com>

Ginger, the rhizome of Zingiber officinalis, one of the most widely used species of the ginger family, is a common condiment for various foods and beverages. Ginger has a long history of medicinal use dating back 2500 years. Ginger has been traditionally used from time immemorial for varied human ailments in different parts of the globe, to aid digestion and treat stomach upset, diarrhoea, and nausea. Some pungent constituents present in ginger and other zingiberaceous plants have potent antioxidant and anti-inflammatory activities, and some of them exhibit cancer preventive activity in experimental carcinogenesis. The anticancer properties of ginger are attributed to the presence of certain pungent vallinoids, viz. [6]-gingerol and [6]-paradol, as well as some other constituents like shogaols, zingerone etc. A number of mechanisms that may be involved in the chemopreventive effects of ginger and its components have been reported from the laboratory studies in a wide range of experimental models.

6.            Streeter CC, Jensen JE, Perlmutter RM, Cabral HJ, Tian H, Terhune DB, Ciraulo DA, Renshaw PF. Yoga Asana sessions increase brain GABA levels: a pilot study. J Altern Complement Med. 2007 May;13(4):419-26.

Division of Psychiatry, Boston University School of Medicine, Boston, MA 02118, USA. streeter@bu.edu

OBJECTIVES: The aim of this study was to compare changes in brain gamma-aminobutyric (GABA) levels associated with an acute yoga session versus a reading session. It was hypothesized that an individual yoga session would be associated with an increase in brain GABA levels. DESIGN: This is a parallel-groups design. SETTINGS/LOCATION: Screenings, scan acquisitions, and interventions took place at medical school-affiliated centers. SUBJECTS: The sample comprised 8 yoga practitioners and 11 comparison subjects. INTERVENTIONS: Yoga practitioners completed a 60-minute yoga session and comparison subjects completed a 60-minute reading session. OUTCOME MEASURES: GABA-to-creatine ratios were measured in a 2-cm axial slab using magnetic resonance spectroscopic imaging immediately prior to and immediately after interventions. RESULTS: There was a 27% increase in GABA levels in the yoga practitioner group after the yoga session (0.20 mmol/kg) but no change in the comparison subject group after the reading session ( -0.001 mmol/kg) (t = -2.99, df = 7.87, p = 0.018). CONCLUSIONS:These findings demonstrate that in experienced yoga practitioners, brain GABA levels increase after a session of yoga. This suggests that the practice of yoga should be explored as a treatment for disorders with low GABA levels such as depression and anxiety disorders. Future studies should compare yoga to other forms of exercise to help determine whether yoga or exercise alone can alter GABA levels.

 

16645.  Abubakar MS, Musa AM, Ahmed A, Hussaini IM. The perception and practice of traditional medicine in the treatment of cancers and inflammations by the Hausa and Fulani tribes of Northern Nigeria. J Ethnopharmacol. 2007 May  22;111(3):625-9.

16646.  Agra MF, Baracho GS, Nurit K, Basilio IJ, Coelho VP.  Medicinal and poisonous  diversity of the flora of "Cariri Paraibano", Brazil. J Ethnopharmacol. 2007 May 4;111(2):383-95.

16647.  Akdogan M, Tamer MN, Cure E, Cure MC, Koroglu BK, Delibas N. Effect of spearmint (Mentha spicata Labiatae) teas on androgen levels in women with hirsutism. Phytother Res. 2007 May;21(5):444-7. 

16648.   Alladin A, Alibhai A. Cognitive hypnotherapy for depression: an empirical investigation. Int J Clin Exp Hypn. 2007 Apr;55(2):147-66. 

16649.  Appendino G, Ottino M, Marquez N, Bianchi F, Giana A, Ballero M, Sterner O, Fiebich BL, Munoz E. Arzanol, an anti-inflammatory and anti-HIV-1 phloroglucinol alpha-Pyrone  from Helichrysum italicum ssp. microphyllum. J Nat Prod. 2007 Apr;70(4):608-12.

16650.  Armitage GD, Suter E, Verhoef MJ, Bockmuehl C, Bobey M.  Women's needs for CAM information to manage menopausal symptoms. Climacteric. 2007 Jun;10(3):215-24. 

16651.   Ayieko P, English M.  Case management of childhood pneumonia in developing countries. Pediatr Infect Dis J. 2007 May;26(5):432-40. 

16652.  Barnhofer T, Duggan D, Crane C, Hepburn S, Fennell MJ, Williams JM.  Effects of meditation on frontal alpha-asymmetry in previously suicidal individuals. Neuroreport. 2007 May 7;18(7):709-12. 

16653.   Basch E.  Expectations for specialized knowledge in oncology: time to reassess. Nat Clin Pract Oncol. 2007 May;4(5):263.

16654.  Berman B.  A 60-year-old woman considering acupuncture for knee pain. JAMA. 2007 Apr 18;297(15):1697-707. Review. 

16655. Bocca S, Stadtmauer L, Oehninger S. Current status of robotically assisted laparoscopic surgery in reproductive medicine and gynaecology. Reprod Biomed Online. 2007 Jun;14(6):765-72. Review. 

16656.  Broom A, Tovey P.  Therapeutic pluralism? Evidence, power and legitimacy in UK cancer services. Sociol Health Illn. 2007 May;29(4):551-69. 

16657.  Cabioglu MT, Ergene N, Tan U.  Electroacupuncture treatment of obesity with psychological symptoms. Int J Neurosci. 2007 May;117(5):579-90. 

16658.  Carod-Artal FJ, Vazquez-Cabrera C.  An anthropological study about headache and migraine in native cultures from Central and South America. Headache. 2007 Jun;47(6):834-41. 

16659.  Carod-Artal FJ, Vazquez-Cabrera CB.  An anthropological study about epilepsy in native tribes from Central and South America. Epilepsia. 2007 May;48(5):886-93. 

16660.  Cartwright T.  'Getting on with life': the experiences of older people using complementary health care. Soc Sci Med. 2007 Apr;64(8):1692-703. Epub 2007 Jan 31. 

16661.  Chandwani BP, Maloney GE, Mehta NR, Scrivani SJ.  Chronic daily headache: case report of one subgroup. J Mass Dent Soc. 2007 Spring;56(1):20-3.

16662.   Chehade M.  IgE and non-IgE-mediated food allergy: treatment in 2007. Curr Opin Allergy Clin Immunol. 2007 Jun;7(3):264-8. Review. 

16663.  Cheuk W, Chan JK, Nuovo G, Chan MK, Fok M.  Regression of gastric large B-Cell lymphoma accompanied by a florid lymphoma-like T-cell reaction: immunomodulatory effect of Ganoderma lucidum (Lingzhi)? Int J Surg Pathol. 2007 Apr;15(2):180-6. 

16664. Chong VH, Yaakub AB.  Hazards of complementary and alternative medicine. Singapore Med J. 2007 Jun;48(6):592; author reply 593.

16665.  Coelho T.  On the experience of epilepsy. Neurology. 2007 May 15;68(20):1737-8.

16666.  Cooper R.  Commentary: herbs as sources for drugs to treat Alzheimer's disease. J Altern Complement Med. 2007 Apr;13(3):347-8.

16667. Coudeyre E, Jardin C, Givron P, Ribinik P, Revel M, Rannou F. Could preoperative rehabilitation modify postoperative outcomes after total hip and knee arthroplasty? Elaboration of French clinical practice guidelines. Ann Readapt Med Phys. 2007 Apr;50(3):189-97.

16668. Coulter ID. Evidence based complementary and alternative medicine: promises and problems. Forsch Komplementarmed. 2007 Apr;14(2):102-8. 

16669.  Cowin I, Emmett P; ALSPAC Study Team.  Diet in a group of 18-month-old children in South West England, and comparison with the results of a national survey. J Hum Nutr Diet. 2007 Jun;20(3):254-67.

16670.  Dhanabal SP. Hypoglycemic and antioxidant activities of Costus mexicanus  (Costaceae). Aryavaidyan 2007, 21(1), 53-58.

16671.  Dog TL.  The role of complementary and alternative medicine during the menopausal transition. Menopause. 2007 May-Jun;14(3 Pt 1):347-9. Review.

16672.   Doren M.  Effects of acupuncture and estrogens on hot flushes. Climacteric. 2007 Jun;10(3):264; author reply 264-5.

16673.  Dufour D, Pichette A, Mshvildadze V, Bradette-Hebert ME, Lavoie S, Longtin A, Laprise C, Legault J.  Antioxidant, anti-inflammatory and anticancer activities of methanolic extracts from Ledum groenlandicum Retzius. J Ethnopharmacol. 2007 Apr 20;111(1):22-8.

16674.  Edris AE.  Pharmaceutical and therapeutic potentials of essential oils and their individual volatile constituents: a review. Phytother Res. 2007 Apr;21(4):308-23. Review. 

16675.  Elavsky S, McAuley E.  Lack of perceived sleep improvement after 4-month structured exercise programs. Menopause. 2007 May-Jun;14(3 Pt 1):535-40. 

16676.   Elliott JR, Manzi S, Edmundowicz D. The role of preventive cardiology in systemic lupus erythematosus. Curr Rheumatol Rep. 2007 May;9(2):125-30. Review. 

16677.  Ernst E, Pittler MH, Wider B, Boddy K.  Complementary therapies for back pain: is the evidence getting stronger? Clin Rheumatol. 2007 May;26(5):736-8.

16678.  Ernst E, Pittler MH, Wider B, Boddy K.  Complementary/alternative medicine for supportive cancer care: development of the evidence-base. Support Care Cancer. 2007 May;15(5):565-8. Epub 2006 Nov 9. Review. 

16679.  Evans JM.  Why we need holism in pregnancy care: a review. Altern Ther Health Med. 2007 May-Jun;13(3):60-3. Review.

16680.  Everett G, Uddin N, Rudloff B.  Comparison of hospital costs and length of stay for community internists, hospitalists, and academicians. J Gen Intern Med. 2007 May;22(5):662-7.

16681.    Feigin VL. Herbal medicine in stroke: does it have a future? Stroke. 2007 Jun;38(6):1734-6.

16682.   Fleming S, Rabago DP, Mundt MP, Fleming MF.  CAM therapies among primary care patients using opioid therapy for chronic pain. BMC Complement Altern Med. 2007 May 16;7:15. 

16683. Fontana M, Zero D.  Bridging the gap in caries management between research and practice through education: the Indiana University experience. J Dent Educ. 2007 May;71(5):579-91. 

16684. Fox J, Kleinberg L.  Evolving management of newly diagnosed brain metastases: expanding role of  radiosurgery in lieu of whole brain radiation. Future Oncol. 2007 Jun;3(3):285-93.

16685. Geller SE, Studee L.  Botanical and dietary supplements for mood and anxiety in menopausal women. Menopause. 2007 May-Jun;14(3 Pt 1):541-9. Review. 

16686. Giannelli M, Cuttini M, Da Fre M, Buiatti E.  General practitioners' knowledge and practice of complementary/alternative medicine and its relationship with life-styles: a population-based survey in Italy. BMC Fam Pract. 2007 May 15;8:30. 

16687. Goldberg RJ, Katz J. A meta-analysis of the analgesic effects of omega-3 polyunsaturated fatty acid supplementation for inflammatory joint pain. Pain. 2007 May;129(1-2):210-23.

16688. Golden WL.  Cognitive-behavioral hypnotherapy in the treatment of irritable-bowel-syndrome-induced agoraphobia. Int J Clin Exp Hypn. 2007 Apr;55(2):131-46. Review. 

16689.  Griebsch I, Knowles RL, Brown J, Bull C, Wren C, Dezateux CA. Comparing the clinical and economic effects of clinical examination, pulse oximetry, and echocardiography in newborn screening for congenital heart defects: a probabilistic cost-effectiveness model and value of information analysis. Int J Technol Assess Health Care. 2007 Spring;23(2):192-204. 

16690.  Gunnarsdottir TJ, Jonsdottir H.  Does the experimental design capture the effects of complementary therapy? A study using reflexology for patients undergoing coronary artery bypass graft surgery. J Clin Nurs. 2007 Apr;16(4):777-85. 

16691.   Hadapad BS, Nayak A, Rai PK. ChronIc venous ulcer � A case report. Aryavaidyan 2007, 21(1), 30-33.

16692.     Hannon K.  From stressed to stressbuster. US News World Rep. 2007 Apr 9;142(12):58-9.

16693.  Hanson E, Kalish LA, Bunce E, Curtis C, McDaniel S, Ware J, Petry J.  Use of complementary and alternative medicine among children diagnosed with autism spectrum disorder. J Autism Dev Disord. 2007 Apr;37(4):628-36. 

16694.   Hayes M, Buckley D, Judkins DZ, Lo V.  Clinical inquiries. Are any alternative therapies effective in treating asthma? J Fam Pract. 2007 May;56(5):385-7. Review.

16695.   Hebert RS, Dang Q, Schulz R.  Religious beliefs and practices are associated with better mental health in family caregivers of patients with dementia: findings from the REACH study. Am J Geriatr Psychiatry. 2007 Apr;15(4):292-300. Epub 2006 Dec 8. 

16696.  Horton-Deutsch S, O'Haver Day P, Haight R, Babin-Nelson M.  Enhancing mental health services to bone marrow transplant recipients through a mindfulness-based therapeutic intervention. Complement Ther Clin Pract. 2007 May;13(2):110-5.

16697.   Ierullo AM, Papageorghiou AT, Bhide A, Fratelli N, Thilaganathan B.  Severe twin-twin transfusion syndrome: outcome after fetoscopic laser ablation of the placental vascular equator. BJOG. 2007 Jun;114(6):689-93. 

16698.   Iwai N, Kume Y, Kimura O, Ono S, Aoi S, Tsuda T. Effects of herbal medicine Dai-Kenchu-to on anorectal function in children with severe constipation. Eur J Pediatr Surg. 2007 Apr;17(2):115-8. 

16699.  Jagadale AA, Deshmukh AA, Bhonsale AV, Patil SG. Determination of minimal inhibitory concentration of methanol extract of Ficus religiosa leaf extract against some pathogenic bacteria. Aryavaidyan 2007, 21(1), 50-52.

16700. Kaiser J, Yassin M, Prakash S, Safi N, Agami M, Lauw S, Ostrozhenkova E, Bacher A, Rohdich F, Eisenreich W, Safi J, Golan-Goldhirsh A.  Anti-malarial drug targets: screening for inhibitors of 2C-methyl-D-erythritol 4-phosphate synthase (IspC protein) in Mediterranean plants. Phytomedicine. 2007 Apr;14(4):242-9.

16701.  Kallet RH, Branson RD.  Respiratory controversies in the critical care setting. Do the NIH ARDS Clinical Trials Network PEEP/FIO2 tables provide the best evidence-based guide to balancing PEEP and FIO2 settings in adults? Respir Care. 2007 Apr;52(4):461-75; discussion 475-7. 

16702. Kaur H, Arunkalaivanan AS.  Urethral pain syndrome and its management. Obstet Gynecol Surv. 2007 May;62(5):348-51; quiz 353-4. Review. 

16703.  King RV, Murphy-Cullen CL, Mayo HG, Marcee AK, Schneider GW.  Use of computers and the Internet by residents in US family medicine programmes. Med Inform Internet Med. 2007 Jun;32(2):149-55. 

16704.  Kinkade S.  Evaluation and treatment of acute low back pain. Am Fam Physician. 2007 Apr 15;75(8):1181-8. Review. Summary for patients in: Am Fam Physician. 2007 Apr 15;75(8):1190-2. 

16705.  Kloucek P, Svobodova B, Polesny Z, Langrova I, Smrcek S, Kokoska L.  Antimicrobial activity of some medicinal barks used in Peruvian Amazon. J Ethnopharmacol. 2007 May 4;111(2):427-9. 

16706.   Koren G.  Complementary and alternative medicine for children--time to enter the evidence-based era. Can J Clin Pharmacol. 2007 Summer;14(2):e103. Epub 2007 Apr 30. 

16707.   Kulakac O, Oncel S, Meydanlioglu A, Muslu L. The opinions of employed mothers about their own nutrition during lactation: a questionnaire survey. Int J Nurs Stud. 2007 May;44(4):589-600. 

16708.   Kwok C, Sullivan G.  The concepts of health and preventive health practices of Chinese Australian women in relation to cancer screening. J Transcult Nurs. 2007 Apr;18(2):118-26. 

16709.   Lee SB, Cha KH, Selenge D, Solongo A, Nho CW.  The chemopreventive effect of taxifolin is exerted through ARE-dependent gene regulation. Biol Pharm Bull. 2007 Jun;30(6):1074-9. 

16710.  Lin HM, Tseng HC, Wang CJ, Chyau CC, Liao KK, Peng PL, Chou FP.   Induction of autophagy and apoptosis by the extract of Solanum nigrum Linn in HepG2 cells. J Agric Food Chem. 2007 May 2;55(9):3620-8.

16711.  Lovas JG, Lovas DA.  Rapid relaxation--practical management of preoperative anxiety. J Can Dent Assoc. 2007 Jun;73(5):437-40. 

16712.  Maa SH, Tsou TS, Wang KY, Wang CH, Lin HC, Huang YH.  Self-administered acupressure reduces the symptoms that limit daily activities in bronchiectasis patients: pilot study findings. J Clin Nurs. 2007 Apr;16(4):794-804. 

16713.  Manheimer E, Linde K, Lao L, Bouter LM, Berman BM.  Meta-analysis: acupuncture for osteoarthritis of the knee. Ann Intern Med. 2007 Jun 19;146(12):868-77.  

16714. Mayhew E, Ernst E. Acupuncture for fibromyalgia--a systematic review of randomized clinical trials. Rheumatology (Oxford). 2007 May;46(5):801-4. Epub 2006 Dec 19. Review. 

16715.  Mills CN, Liebmann O, Stone MB, Frazee BW.  Ultrasonographically guided insertion of a 15-cm catheter into the deep brachial or basilic vein in patients with difficult intravenous access. Ann Emerg Med. 2007 Jul;50(1):68-72.

16716. Mothana RA, Grunert R, Lindequist U, Bednarski PJ.  Study of the anticancer potential of Yemeni plants used in folk medicine. Pharmazie. 2007 Apr;62(4):305-7. 

16717. Mullai V, Menon T.  Bactericidal activity of different types of honey against clinical and environmental isolates of Pseudomonas aeruginosa. J Altern Complement Med. 2007 May;13(4):439-41. 

16718. Myklebust M, Iler J.  Policy for therapeutic massage in an academic health center: a model for standard policy development. J Altern Complement Med. 2007 May;13(4):471-5. 

16719.  Neighbors HW, Caldwell C, Williams DR, Nesse R, Taylor RJ, Bullard KM, Torres M, Jackson JS.  Race, ethnicity, and the use of services for mental disorders: results from the National Survey of American Life. Arch Gen Psychiatry. 2007 Apr;64(4):485-94. 

16720.  Neuman MI, Willett WC, Curhan GC.  Vitamin and micronutrient intake and the risk of community-acquired pneumonia in US women. Am J Med. 2007 Apr;120(4):330-6. 

16721.  Nilsson M, Pekny M.  Enriched environment and astrocytes in central nervous system regeneration. J Rehabil Med. 2007 May;39(5):345-52. Review. 

16722.  Owens JE, Holstege DM, Clifford AJ.  Comparison of two dietary folate intake instruments and their validation by RBC folate. J Agric Food Chem. 2007 May 2;55(9):3737-40.

16723.  Pang BC, Cheung BK.  Identification of human semenogelin in membrane strip test as an alternative method for the detection of semen. Forensic Sci Int. 2007 Jun 14;169(1):27-31.

16724.  Peng WN, Zhao H, Liu ZS, Wang S.  Acupuncture for vascular dementia. Cochrane Database Syst Rev. 2007 Apr 18;(2):CD004987. Review. 

16725.  Pennick VE, Young G.  Interventions for preventing and treating pelvic and back pain in pregnancy. Cochrane Database Syst Rev. 2007 Apr 18;(2):CD001139. Review. 

16726.   Pierce B.  The use of biofield therapies in cancer care. Clin J Oncol Nurs. 2007 Apr;11(2):253-8. Review. 

16727.   Pridmore S. Re: "Work related stress and pain". Aust Fam Physician. 2007 Apr;36(4):199.

16728.   Purohit A, Rathore J, Vyas KB. Antifertility effect of Lindenbergia indica in male albino rats: A morphometric approach. Aryavaidyan 2007, 21(1), 11-17.

16729. Rajni Chandre, JS Tripathi. Role of Sirovasti in the management of Kampavata vis-�-vis Parkinsonism. Aryavaidyan 2007, 21(1), 25-29.

16730. Ramachandran C, Nair PK, Clement RT, Melnick SJ.  Investigation of cytokine expression in human leukocyte cultures with two immune-modulatory homeopathic preparations. J Altern Complement Med. 2007 May;13(4):403-7. 

16731.  Rathbone J, Zhang L, Zhang M, Xia J, Liu X, Yang Y, Adams CE.  Chinese herbal medicine for schizophrenia: cochrane systematic review of randomised trials. Br J Psychiatry. 2007 May;190:379-84. Review. 

16732. Riggs NR, Sakuma KL, Pentz MA.  Preventing risk for obesity by promoting self-regulation and decision-making skills: pilot results from the PATHWAYS to health program (PATHWAYS). Eval Rev. 2007 Jun;31(3):287-310. 

16733. Scotti MT, Fernandes MB, Ferreira MJ, Emerenciano VP.  Quantitative structure-activity relationship of sesquiterpene lactones with cytotoxic activity. Bioorg Med Chem. 2007 Apr 15;15(8):2927-34.

16734. Shin BC, Lim HJ, Lee MS.  Effectiveness of combined acupuncture therapy and conventional treatment on shoulder range of motion and motor power in stroke patients with hemiplegic shoulder subluxation: a pilot study. Int J Neurosci. 2007 Apr;117(4):519-23.

16735.  Sidora-Arcoleo K, Yoos HL, McMullen A, Kitzman H. Complementary and alternative medicine use in children with asthma: prevalence and sociodemographic profile of users. J Asthma. 2007 Apr;44(3):169-75.  

16736. Soden SE, Lowry JA, Garrison CB, Wasserman GS.  24-hour provoked urine excretion test for heavy metals in children with autism and typically developing controls, a pilot study. Clin Toxicol (Phila). 2007 Jun-Aug;45(5):476-81. 

16737. Srikumar R, Parthasarathy NJ, Shankar EM, Manikandan S, Vijayakumar R, Thangaraj R, Vijayananth K, Sheeladevi R, Rao UA. Evaluation of the growth inhibitory activities of Triphala against common bacterial isolates from HIV infected patients. Phytother Res. 2007 May;21(5):476-80. 

16738.  Stickel F, Schuppan D.  Herbal medicine in the treatment of liver diseases. Dig Liver Dis. 2007 Apr;39(4):293-304.

16739.  Teixeira MZ.  Bronchodilators, fatal asthma, rebound effect and similitude. Homeopathy. 2007 Apr;96(2):135-7.

16740.  Thyagarajan A, Zhu J, Sliva D.  Combined effect of green tea and Ganoderma lucidum on invasive behavior of breast cancer cells. Int J Oncol. 2007 Apr;30(4):963-9. 

16741.  Toneatto T, Nguyen L. Does mindfulness meditation improve anxiety and mood symptoms? A review of the controlled research. Can J Psychiatry. 2007 Apr;52(4):260-6. Review. 

16742.   Tripathy PK. Eczema � An ayurvedic perspective. Aryavaidyan 2007, 21(1), 38-40.

16743.   Unnikrishnan. Excerpts form Cikitsamanjari � LV. Aryavaidyan 2007, 21(1), 59-63.

16744.  Verhoef M.  News from the International Society for Complementary Medicine Research. J Altern Complement Med. 2007 May;13(4):477-8.

16745.  Verma S, Thuluvath PJ.  Complementary and alternative medicine in hepatology: review of the evidence of efficacy. Clin Gastroenterol Hepatol. 2007 Apr;5(4):408-16.

16746.   Wang GY, Zhang JW, Lu QH, Xu RZ, Dong QH.  Berbamine induces apoptosis in human hepatoma cell line SMMC7721 by loss in mitochondrial transmembrane potential and caspase activation. J Zhejiang Univ Sci B. 2007 Apr;8(4):248-55.  

16747.   Wei X, Chen ZY, Yang XY, Wu TX.  Medicinal herbs for esophageal cancer. Cochrane Database Syst Rev. 2007 Apr 18;(2):CD004520. Review. 

16748.  Williams RM, Westmorland MG, Lin CA, Schmuck G, Creen M.  Effectiveness of workplace rehabilitation interventions in the treatment of work-related low back pain: a systematic review. Disabil Rehabil. 2007 Apr 30;29(8):607-24. Review. 

16749.   Wright S. Meditation matters. Nurs Stand. 2007 Jun 6-12;21(39):18-9. 

16750.   Wu B, Liu M, Liu H, Li W, Tan S, Zhang S, Fang Y. Meta-analysis of traditional Chinese patent medicine for ischemic stroke. Stroke. 2007 Jun;38(6):1973-9.

16751.   Wu B, Liu M, Zhang S.  Dan Shen agents for acute ischaemic stroke. Cochrane Database Syst Rev. 2007 Apr 18;(2):CD004295. Review. 

16752.  Wu K, Jiang L, Cao J, Yang G, Geng C, Zhong L.  Genotoxic effect and nitrative DNA damage in HepG2 cells exposed to aristolochic acid. Mutat Res. 2007 Jun 15;630(1-2):97-102.

16753. Ye CL, Liu Y, Wei DZ.  Antioxidant and anticancer activity of 3'-formyl-4', 6'-dihydroxy-2'-methoxy-5'-methylchalcone and (2S)-8-formyl-5-hydroxy-7-methoxy-6-methylflavanone. J Pharm Pharmacol. 2007 Apr;59(4):553-9. 

16754.  Zeichner JA, Lebwohl M. Potential complications associated with the use of biologic agents for psoriasis. Dermatol Clin. 2007 Apr;25(2):207-13, vii. Review. 

16755.  Zhang GL, Li N, Wang YH, Zheng YT, Zhang Z, Wang MW.  Bioactive lignans from Peperomia heyneana. J Nat Prod. 2007 Apr;70(4):662-4. 

16756.  Zhou GB, Kang H, Wang L, Gao L, Liu P, Xie J, Zhang FX, Weng XQ, Shen ZX, Chen J, Gu LJ, Yan M, Zhang DE, Chen SJ, Wang ZY, Chen Z.  Oridonin, a diterpenoid extracted from medicinal herbs, targets AML1-ETO fusion protein and shows potent antitumor activity with low adverse effects on t(8;21) leukemia in vitro and in vivo. Blood. 2007 Apr 15;109(8):3441-50.

16757. Zumsteg IS, Weckerle CS.  Bakera, a herbal steam bath for postnatal care in Minahasa (Indonesia): documentation of the plants used and assessment of the method. J Ethnopharmacol. 2007 May 22;111(3):641-50.

 

Back