Diagnosis, Diagnostics, Immunodiagnosis & Immunodiagnostics:

9125.  Adinolfi LE. Prevalence and incidence of cryoglobulins in chronic hepatitis C patients. Am J Gastroenterol. 2003 Nov;98(11):2568-9; author reply 2569-70.

9126.  Annet L, Materne R, Danse E, Jamart J, Horsmans Y, Van Beers BE. Hepatic flow parameters measured with MR imaging and Doppler US: correlations with degree of cirrhosis and portal hypertension. Radiology. 2003 Nov;229(2):409-14. Epub 2003 Sep 11.

9127.  Bai YJ, Zhao JR, Lv GT, Zhang WH, Wang Y, Yan XJ. Rapid and high throughput detection of HBV YMDD mutants with fluorescence polarization. World J Gastroenterol. 2003 Oct;9(10):2344-7.

9128.  Bajaj J, Knox JF, Komorowski R, Saeian K. The irony of herbal hepatitis: Ma-Huang-induced hepatotoxicity associated with compound heterozygosity for hereditary hemochromatosis. Dig Dis Sci. 2003 Oct;48(10):1925-8.

9129.  Barth H, Schafer C, Adah MI, Zhang F, Linhardt RJ, Toyoda H, Kinoshita-Toyoda A, Toida T, Van Kuppevelt TH, Depla E, Von Weizsacker F, Blum HE, Baumert TF.  Cellular binding of hepatitis C virus envelope glycoprotein E2 requires cell surface heparan sulfate. J Biol Chem. 2003 Oct 17;278(42):41003-12. Epub 2003 Jul 16.

9130.  Batey RG. Chronic hepatitis C. Aust Fam Physician. 2003 Oct;32(10):807-11.

9131.  Bedossa P, Dargere D, Paradis V. Sampling variability of liver fibrosis in chronic hepatitis C. Hepatology. 2003 Dec;38(6):1449-57.

9132.  Bonacchi A, Petrai I, Defranco RM, Lazzeri E, Annunziato F, Efsen E, Cosmi L, Romagnani P, Milani S, Failli P, Batignani G, Liotta F, Laffi G, Pinzani M, Gentilini P, Marra F. The chemokine CCL21 modulates lymphocyte recruitment and fibrosis in chronic hepatitis C. Gastroenterology. 2003 Oct;125(4):1060-76.

9133.  Brook MG, Gilson R, Wilkins EL; British HIV Association. BHIVA Guidelines: coinfection with HIV and chronic hepatitis B virus. HIV Med. 2003 Oct;4 Suppl 1:42-51.

9134.  Castera L, Pawlotsky JM, Dhumeaux D. Worsening of steatosis and fibrosis progression in hepatitis C. Gut. 2003 Oct;52(10):1531.

9135.  Chaudhuri V, Nanu A, Panda SK, Chand P. Evaluation of serologic screening of blood donors in India reveals a lack of correlation between anti-HBc titer and PCR-amplified HBV DNA. Transfusion. 2003 Oct;43(10):1442-8.

9136.  Choi S. Nefazodone (Serzone) withdrawn because of hepatotoxicity. CMAJ. 2003 Nov 25;169(11):1187.

9137.  Cortez-Pinto H, Baptista A, Camilo ME, De Moura MC. Nonalcoholic steatohepatitis--a long-term follow-up study: comparison with alcoholic hepatitis in ambulatory and hospitalized patients. Dig Dis Sci. 2003 Oct;48(10):1909-13.

9138.  De Ridder RJ, Stronkhorst A. Effect of long-term lamivudine therapy on histological outcome in chronic hepatitis B. Gastroenterology. 2003 Oct;125(4):1286-7;

9139.  Dore GJ, MacDonald M, Law MG, Kaldor JM. Epidemiology of hepatitis C virus infection in Australia. Aust Fam Physician. 2003 Oct;32(10):796-8.

9140.  Goolsby MJ. Screening, diagnosis, and monitoring of hepatic injury. J Am Acad Nurse Pract. 2003 Oct;15(10):434-7.

9141.  Halfon P, Khiri H, Tran A, Penaranda G, Courcambeck J, Joly H, Ouzan D. Hepatitis C virus RNA load in relapsed patients: week two of treatment is the best time to predict the complete response. Eur J Gastroenterol Hepatol. 2003 Oct;15(10):1067-71.

9142.  Hou CS, Wang GQ, Lu SL, Yue B, Li MR, Wang XY, Yu JW. Role of activation-induced cell death in pathogenesis of patients with chronic hepatitis B. World J Gastroenterol. 2003 Oct;9(10):2356-8.

9143.  Johanson FD, Balliram DB. Successful treatment of hepatitis C in a patient with advanced AIDS and decompensated cirrhosis. AIDS Read. 2003 Oct;13(10):494-6, 500-1.

9144.  Kiyici M, Gurel S, Budak F, Dolar E, Gulten M, Nak SG, Memik F. Fas antigen (CD95) expression and apoptosis in hepatocytes of patients with chronic viral hepatitis. Eur J Gastroenterol Hepatol. 2003 Oct;15(10):1079-84.

9145.  Laine S, Thouard A, Derancourt J, Kress M, Sitterlin D, Rossignol JM. In vitro and in vivo interactions between the hepatitis B virus protein P22 and the cellular protein gC1qR. J Virol. 2003 Dec;77(23):12875-80.

9146.  Liu CJ, Kao JH, Chen DS. Molecular assays for hepatitis B virus infection. Hepatology. 2003 Nov;38(5):1311.

9147.  Malaty HM, Tanaka E, Kumagai T, Ota H, Kiyosawa K, Graham DY, Katsuyama T.  Seroepidemiology of Helicobacter pylori and hepatitis A virus and the mode of transmission of infection: a 9-year cohort study in rural Japan. Clin Infect Dis. 2003 Oct 15;37(8):1067-72. Epub 2003 Sep 23.

9148.  Manesis EK, Papatheodoridis GV, Sevastianos V, Cholongitas E, Papaioannou C, Hadziyannis SJ. Significance of hepatitis B viremia levels determined by a quantitative polymerase chain reaction assay in patients with hepatitis B e antigen-negative chronic hepatitis B virus infection. Am J Gastroenterol. 2003 Oct;98(10):2261-7.

9149.  Mathurin P, Abdelnour M, Ramond MJ, Carbonell N, Fartoux L, Serfaty L, Valla D, Poupon R, Chaput JC, Naveau S. Early change in bilirubin levels is an important prognostic factor in severe alcoholic hepatitis treated with prednisolone. Hepatology. 2003 Dec;38(6):1363-9.

9150.  Mondelli  MU, Cerino A, Meola A, Nicosia A Variability or conservation of hepatitis C virus hypervariable region 1? Implications for immune responses.  J Biosci, Bangalore 2003; 28(3): 305-10.

9151.  Nevens F, Roskams T, Van Vlierberghe H, Horsmans Y, Sprengers D, Elewaut A, Desmet V, Leroux-Roels G, Quinaux E, Depla E, Dincq S, Vander Stichele C, Maertens G, Hulstaert F.  A pilot study of therapeutic vaccination with envelope protein E1 in 35 patients with chronic hepatitis C. Hepatology. 2003 Nov;38(5):1289-96.

9152.  Operskalski EA, Mosley JW, Tobler LH, Fiebig EW, Nowicki MJ, Mimms LT, Gallarda J, Phelps BH, Busch MP; Transfusion-Transmitted Viruses Study; Retrovirus Epidemiology Donor Study. HCV viral load in anti-HCV-reactive donors and infectivity for their recipients. Transfusion. 2003 Oct;43(10):1433-41.

9153.  Petit MA, Jolivet-Reynaud C, Peronnet E, Michal Y, Trepo C. Mapping of a conformational epitope shared between E1 and E2 on the serum-derived human hepatitis C virus envelope. J Biol Chem. 2003 Nov 7;278(45):44385-92. Epub 2003 Jul 24.

9154.  Pisani G, Cristiano K, Bisso G, Wirz M, Mele C, Gentili G. HBV DNA in plasma pools fractionation. Transfusion. 2003 Dec;43(12):1763-4.

9155.  Ren F, Hino K, Yamaguchi Y, Funatsuki K, Hayashi A, Ishiko H, Furutani M, Yamasaki T, Korenaga K, Yamashita S, Konishi T, Okita K. Cytokine-dependent anti-viral role of CD4-positive T cells in therapeutic vaccination against chronic hepatitis B viral infection. J Med Virol. 2003 Nov;71(3):376-84.

9156.  Rubinstein ML, Miele ME.   Hepatitis C virus infection: detection and treatment. Clin Lab Sci. 2003 Fall;16(4):203-8. Review.

9157.  Safadi R, Israeli E, Papo O, Shibolet O, Melhem A, Bloch A, Rowe M, Alper R, Klein A, Hemed N, Segol O, Thalenfeld B, Engelhardt D, Rabbani E, Ilan Y. Treatment of chronic hepatitis B virus infection via oral immune regulation toward hepatitis B virus proteins. Am J Gastroenterol. 2003 Nov;98(11):2505-15.

9158.  Smith MW, Yue ZN, Korth MJ, Do HA, Boix L, Fausto N, Bruix J, Carithers RL Jr, Katze MG. Hepatitis C virus and liver disease: global transcriptional profiling and identification of potential markers. Hepatology. 2003 Dec;38(6):1458-67.

9159.  Sterling RK.  Triple infection with human immunodeficiency virus, hepatitis C virus, and hepatitis B virus: a clinical challenge. Am J Gastroenterol. 2003 Oct;98(10):2130-4.

9160.  Tao J, Peng HQ, Cai WM, Dong FQ, Weng HL, Liu RH.  Influence factors of serum fibrosis markers in liver fibrosis. World J Gastroenterol. 2003 Nov;9(11):2497-500.

9161.  Vogt S, Schneider-Stock R, Klauck S, Roessner A, Rocken C. Detection of hepatitis C virus RNA in formalin-fixed, paraffin-embedded thin-needle liver biopsy specimens. Am J Clin Pathol. 2003 Oct;120(4):536-43.

9162.  Wong JB, Davis GL, McHutchison JG, Manns MP, Albrecht JK; International Hepatitis Interventional Therapy Group. Economic and clinical effects of evaluating rapid viral response to peginterferon alfa-2b plus ribavirin for the initial treatment of chronic hepatitis C. Am J Gastroenterol. 2003 Nov;98(11):2354-62.

9163.  Xu B, Broome U, Uzunel M, Nava S, Ge X, Kumagai-Braesch M, Hultenby K, Christensson B, Ericzon BG, Holgersson J, Sumitran-Holgersson S. Capillarization of hepatic sinusoid by liver endothelial cell-reactive autoantibodies in patients with cirrhosis and chronic hepatitis. Am J Pathol. 2003 Oct;163(4):1275-89.

Pathogenesis:

9164.  Ahn SH, Kramvis A, Kawai S, Spangenberg HC, Li J, Kimbi G, Kew M, Wands J, Tong S.  Sequence variation upstream of precore translation initiation codon reduces hepatitis B virus e antigen production. Gastroenterology. 2003 Nov;125(5):1370-8.

9165.  Armstrong GL. Commentary: Modelling the epidemiology of hepatitis C and its complications. Int J Epidemiol. 2003 Oct;32(5):725-6.

9166.  Barrett S, Collins M, Kenny C, Ryan E, Keane CO, Crowe J. Polymorphisms in tumour necrosis factor-alpha, transforming growth factor-beta, interleukin-10, interleukin-6, interferon-gamma, and outcome of hepatitis C virus infection. J Med Virol. 2003 Oct;71(2):212-8.

9167.  Boulestin A, Sandres-Saune K, Payen JL, Rostaing L, Pasquier C, Izopet J. Genetic heterogeneity of the NS5A gene of hepatitis C virus and early response to interferon-alpha. J Infect Dis. 2003 Nov 1;188(9):1367-70. Epub 2003 Oct 13.

9168.  Chiavetta JA, Escobar M, Newman A, He Y, Driezen P, Deeks S, Hone DE, O'Brien SF, Sher G. Incidence and estimated rates of residual risk for HIV, hepatitis C, hepatitis B and human T-cell lymphotropic viruses in blood donors in Canada, 1990-2000. CMAJ. 2003 Oct 14;169(8):767-73.

9169.  De Ridder RJ, Stronkhorst A. Effect of long-term lamivudine therapy on histological outcome in chronic hepatitis B. Gastroenterology. 2003 Oct;125(4):1286-7;

9170.  Franco S, Gimenez-Barcons M, Puig-Basagoiti F, Furcic I, Sanchez-Tapias JM, Rodes J, Saiz JC. Characterization and evolution of NS5A quasispecies of hepatitis C virus genotype 1b in patients with different stages of liver disease. J Med Virol. 2003 Oct;71(2):195-204.

9171.  Fujioka S, Shimomura H, Iwasaki Y, Fujio K, Nakagawa H, Onishi Y, Takagi S, Taniguchi H, Umeoka F, Nakajima H, Moriya A, Nanba K, Piao CY, Shinji T, Koide N, Shiratori Y. Hepatitis B virus gene in liver tissue promotes hepatocellular carcinoma development in chronic hepatitis C patients. Dig Dis Sci. 2003 Oct;48(10):1920-4.

9172.  Gaya DR, Thorburn D, Oien KA, Morris AJ, Stanley AJ. Hepatic granulomas: a 10 year single centre experience. J Clin Pathol. 2003 Nov;56(11):850-3.

9173.  Giannini E, Botta F, Borro P, Malfatti F, Fumagalli A, Testa E, Podesta E, Chiarbonello B, Polegato S, Mamone M, Testa R. Relationship between thrombopoietin serum levels and liver function in patients with chronic liver disease related to hepatitis C virus infection. Am J Gastroenterol. 2003 Nov;98(11):2516-20.

9174.  Kong HJ, Park MJ, Hong S, Yu HJ, Lee YC, Choi YH, Cheong J. Hepatitis B virus X protein regulates transactivation activity and protein stability of the cancer-amplified transcription coactivator ASC-2. Hepatology. 2003 Nov;38(5):1258-66.

9175.  Lake-Bakaar G, Frost SD. Viral kinetics and hepatitis C. Hepatology. 2003 Dec;38(6):1588.

9176.  Law MG, Dore GJ, Bath N, Thompson S, Crofts N, Dolan K, Giles W, Gow P, Kaldor J, Loveday S, Powell E, Spencer J, Wodak A. Modelling hepatitis C virus incidence, prevalence and long-term sequelae in Australia, 2001. Int J Epidemiol. 2003 Oct;32(5):717-24.

9177.  Macnaughton TB, Li YI, Doughty AL, Lai MM. Hepatitis delta virus RNA encoding the large delta antigen cannot sustain replication due to rapid accumulation of mutations associated with RNA editing. J Virol. 2003 Nov;77(22):12048-56.

9178.  Matskevich AA, Strayer DS. Exploiting hepatitis C virus activation of NFkappaB to deliver HCV-responsive expression of interferons alpha and gamma. Gene Ther. 2003 Oct;10(22):1861-73.

9179.  Milich D, Liang TJ.  Exploring the biological basis of hepatitis B e antigen in hepatitis B virus infection. Hepatology. 2003 Nov;38(5):1075-86. Review.

9180.  Mueller T, Gessner R, Sarrazin C, Graf C, Halangk J, Witt H, Kottgen E, Wiedenmann B, Berg T. Apolipoprotein E4 allele is associated with poor treatment response in hepatitis C virus (HCV) genotype 1. Hepatology. 2003 Dec;38(6):1592;

9181.  Muhlbauer M, Bosserhoff AK, Hartmann A, Thasler WE, Weiss TS, Herfarth H, Lock G, Scholmerich J, Hellerbrand C. A novel MCP-1 gene polymorphism is associated with hepatic MCP-1 expression and severity of HCV-related liver disease. Gastroenterology. 2003 Oct;125(4):1085-93.

9182.  Ohata K, Ichikawa T, Nakao K, Shigeno M, Nishimura D, Ishikawa H, Hamasaki K, Eguchi K. Interferon alpha inhibits the nuclear factor kappa B activation triggered by X gene product of hepatitis B virus in human hepatoma cells. FEBS Lett. 2003 Oct 23;553(3):304-8.

9183.  Park SG, Lee SM, Jung G. Antisense oligodeoxynucleotides targeted against molecular chaperonin Hsp60 block human hepatitis B virus replication. J Biol Chem. 2003 Oct 10;278(41):39851-7. Epub 2003 Jul 16.

9184.  Risbud A, Pereira M, Meherdale S, Gangakhedkar R, Ghate M, Joshi S, Tripathy S.  Lack of evidence for sexual transmission of hepatitis C virus in patients attending STD clinics in Pune, India. Sex Transm Infect. 2003 Oct;79(5):425.

9185.  Rubinstein ML, Miele ME. Hepatitis C virus infection: detection and treatment. Clin Lab Sci. 2003 Fall;16(4):203-8. Review.

9186.  Schleicher SB, Flehmig BF. Genotyping of GB virus C by restriction pattern analysis of the 5' untranslated region. J Med Virol. 2003 Oct;71(2):226-32.

9187.  Steyaert S, Vanlandschoot P, Van Vlierberghe H, Diepolder H, Leroux-Roels G. Soluble CD14 levels are increased and inversely correlated with the levels of hepatitis B surface antigen in chronic hepatitis B patients. J Med Virol. 2003 Oct;71(2):188-94.

9188.  Watashi K, Hijikata M, Hosaka M, Yamaji M, Shimotohno K. Cyclosporin A suppresses replication of hepatitis C virus genome in cultured hepatocytes. Hepatology. 2003 Nov;38(5):1282-8.

9189.  Wright-Kanuth MS, Smith LA. Transfusion-transmitted viruses. Clin Lab Sci. 2003 Fall;16(4):221-9. Review.

9190.  Yeh CT, Hwang DR, Lai HY, Hsu JT. Inhibition of authentic hepatitis C virus replication by sodium stibogluconate. Biochem Biophys Res Commun. 2003 Oct 17;310(2):537-41.

9191.  Zuckerman E, Kessel A, Slobodin G, Sabo E, Yeshurun D, Toubi E.  Antiviral treatment down-regulates peripheral B-cell CD81 expression and CD5 expansion in chronic hepatitis C virus infection. J Virol. 2003 Oct;77(19):10432-6.

9192.  Zwahlen M, Vlahov D. Commentary: Modelling and understanding differences in human immunodeficiency and hepatitis C virus epidemiology in injection drug users. Int J Epidemiol. 2003 Oct;32(5):715-6.

Vaccines:

9193.  Bardenheier B, Gonzalez IM, Washington ML, Bell BP, Averhoff F, Massoudi MS, Hyams I, Simard EP, Yusuf H. Parental knowledge, attitudes, and practices associated with not receiving hepatitis A vaccine in a demonstration project in Butte County, California. Pediatrics. 2003 Oct;112(4):e269.

9194.  Jacobs RJ, Meyerhoff AS.  Cost-effectiveness of hepatitis A/B vaccine versus hepatitis B vaccine in public sexually transmitted disease clinics. Sex Transm Dis. 2003 Nov;30(11):859-65.

9195.  Patrick DM, Bigham M, Ng H, White R, Tweed A, Skowronski DM. Elimination of acute hepatitis B among adolescents after one decade of an immunization program targeting Grade 6 students. Pediatr Infect Dis J. 2003 Oct;22(10):874-7.

9196.  Wang RX, Boland G, Guo Y, Lei SP, Yang CH, Chen J, Tian J, Wen JY, Du KH, van Hattum J, de Gast GC. Is a low dose of hepatitis B vaccine enough for a rapid vaccination scheme? World J Gastroenterol. 2003 Oct;9(10):2353-5.

Therapy:

9197.  Bernstein D. Cost-effectiveness of treatment for chronic hepatitis C infection. JAMA. 2003 Oct 15;290(15):1993;

9198.  De Ridder RJ, Stronkhorst A. Effect of long-term lamivudine therapy on histological outcome in chronic hepatitis B. Gastroenterology. 2003 Oct;125(4):1286-7.

9199.  Dietitians of Canada. Hepatitis C: nutrition care Canadian guidelines for health care providers. Can J Diet Pract Res. 2003 Fall;64(3):139-41.

9200.  Ghany MG, Kleiner DE. E1 therapeutic vaccination for chronic hepatitis C: all that glitters is not gold. Hepatology. 2003 Nov;38(5):1092-4. Review.

9201.  Hagmann S, Chung M, Rochford G, Jani M, Trinh-Shevrin C, Sitnitskaya Y, Neumann AU, Pollack H. Response to lamivudine treatment in children with chronic hepatitis B virus infection. Clin Infect Dis. 2003 Dec 1;37(11):1434-40. Epub 2003 Nov 06.

9202.  Nierengarten MB. Progress on the treatment of hepatitis C. Lancet Infect Dis. 2003 Dec;3(12):748.

9203.  Sidhu-Malik NK, Kaplan AL. Multiple fixed drug eruption with interferon/ribavirin combination therapy for hepatitis C virus infection. J Drugs Dermatol. 2003 Oct;2(5):570-3.  

9204. Zoulim F. Treatment of pre- and post-liver transplantation HBV infection: Should we aim at combination therapy? Hepatology. 2003 Dec;38(6):1353-5.