MALARIA
Some Selected Abstracts: | |
1. |
Amexo M, Tolhurst R, Barnish G, Bates I. Malaria
misdiagnosis: effects on the poor and vulnerable. Lancet. 2004 Nov
20;364(9448):1896-8. Liverpool School of Tropical Medicine, Liverpool L3 5QA, UK. CONTEXT: Effective and affordable treatment is recommended for all cases of malaria within 24 h of the onset of illness. Most cases of "malaria" (ie, fever) are self-diagnosed and most treatments, and deaths, occur at home. The most ethical and cost-effective policy is to ensure that newer drug combinations are only used for true cases of malaria. Although it is cost effective to improve the accuracy of malaria diagnosis, simple, accurate, and inexpensive methods are not widely available, particularly in poor communities where they are most needed. STARTING POINT: In a recent study in Uganda, Karin Kallander and colleagues emphasise the difficulty in making a presumptive diagnosis of malaria, and highlight the urgent need for improved diagnostic tools that can be used at community and primary-care level, especially in poorer populations (Acta Trop 2004; 90: 211-14). WHERE NEXT? Health systems need strengthening at referral and community level, so that rapid accurate diagnosis and effective treatment is available for those who are least able to withstand the consequences of illness. Indirect evidence strongly suggests that misdiagnosis of malaria contributes to a vicious cycle of increasing ill-health and deepening poverty. Much better direct evidence is needed about why and how misdiagnosis affects the poor and vulnerable. |
2. |
Mackintosh
CL, Beeson JG, Marsh K. Clinical features and pathogenesis of severe malaria.
Trends Parasitol. 2004 Dec;20(12):597-603. Centre
for Geographic Medicine Research Coast, Kenya Medical Research Institute
Wellcome Trust Collaborative Programme, Kilifi, Kenya. A major change in recent years has been the recognition that severe malaria, predominantly caused by Plasmodium falciparum, is a complex multi-system disorder presenting with a range of clinical features. It is becoming apparent that syndromes such as cerebral malaria, which were previously considered relatively clear cut, are not homogenous conditions with a single pathological correlate or pathogenic process. This creates challenges both for elucidating key mechanisms of disease and for identifying suitable targets for adjunctive therapy. The development of severe malaria probably results from a combination of parasite-specific factors, such as adhesion and sequestration in the vasculature and the release of bioactive molecules, together with host inflammatory responses. These include cytokine and chemokine production and cellular infiltrates. This review summarizes progress in several areas presented at a recent meeting. |
3. |
Richter
J, de Bernardis C, Sagir A, Walter S, Savalli E, Haussinger D.
Is ultrasound a useful adjunct for assessing malaria patients?
Parasitol Res. 2004 Nov;94(5):349-53. Tropical
Medicine Unit, Clinic for Gastroenterology, Hepatology and Infectious
Diseases, Heinrich-Heine-University, 40225 Duesseldorf, Germany.
Joachim.Richter@med.uni-duesseldorf.de The
value of ultrasonography as an adjunct for diagnosis and monitoring
malaria was investigated. In all, 118 patients (male/female 65/53; age
2-78 years, median 29 years) with malaria underwent a standardised
abdominal ultrasound examination at baseline. In 62 out of 118 patients,
ultrasonography was repeated 21 days later. In the results at baseline,
huge splenomegaly with firm organ consistency, consistent with
hyperreactive malarious splenomegaly syndrome, was observed in two
Cameroonese children. In the other 116 patients, the most common finding
was non-specific splenomegaly (96/116, 82.76%), occurring more
frequently in non-immune patients (71/78, 91.03%) than in patients who
had grown up in malaria-endemic areas (25/38, 65.79%; P<0.002). No
correlation was found between liver or spleen size and any clinical
parameter. The results on day 21 show that, although splenomegaly after
therapy persisted more frequently in patients with malaria recrudescence
or relapse (8/8, 100%) than in patients cured (32/54, 59.26%;
P<0.0421), the practical value of this finding is questionable.
Ultrasonography cannot be regarded as a first-line diagnostic method in
patients with malaria. |
4. |
Walsh DS, Eamsila C, Sasiprapha T, Sangkharomya S, Khaewsathien P, Supakalin P, Tang DB, Jarasrumgsichol P, Cherdchu C, Edstein MD, Rieckmann KH, Brewer TG. Efficacy of monthly tafenoquine for prophylaxis of Plasmodium vivax and multidrug-resistant P. falciparum malaria. J Infect Dis. 2004 Oct 15;190(8):1456-63. Department of Immunology and Medicine, United States Army Medical Component, Bangkok, Thailand. douglas.walsh@se.amedd.army.mil. We
assessed monthly doses of tafenoquine for preventing Plasmodium vivax
and multidrug-resistant P. falciparum malaria. In a randomized,
double-blind, placebo-controlled study, 205 Thai soldiers received
either a loading dose of tafenoquine 400 mg (base) daily for 3 days,
followed by single monthly 400-mg doses (n = 104), or placebo (n = 101),
for up to 5 consecutive months. In volunteers completing follow-up (96
tafenoquine and 91 placebo recipients), there were 22 P. vivax, 8 P.
falciparum, and 1 mixed infection. All infections except 1 P. vivax
occurred in placebo recipients, giving tafenoquine a protective efficacy
of 97% for all malaria (95% confidence interval [CI], 82%-99%), 96% for
P. vivax malaria (95% CI, 76%-99%), and 100% for P. falciparum malaria
(95% CI, 60%-100%). Monthly tafenoquine was safe, well tolerated, and
highly effective in preventing P. vivax and multidrug-resistant P.
falciparum malaria in Thai soldiers during 6 months of prophylaxis.
Copyright 2004 Infectious Diseases Society of America |
5. |
Ayi K, Turrini F, Piga A, Arese P. Enhanced phagocytosis of ring-parasitized mutant erythrocytes: a common mechanism that may explain protection against falciparum malaria in sickle trait and beta-thalassemia trait. Blood. 2004 Nov 15;104(10):3364-71. Dipartimento
di Genetica, Biologia e Biochimica, Universita di Torino, Italy. High
frequency of erythrocyte (red blood cell [RBC]) genetic disorders such
as sickle cell trait, thalassemia trait, homozygous hemoglobin C (Hb-C),
and glucose-6-phosphate dehydrogenase (G6PD) deficiency in regions with
high incidence of Plasmodium falciparum malaria and case-control studies
support the protective role of those conditions. Protection has been
attributed to defective parasite growth or to enhanced removal of the
parasitized RBCs. We suggested enhanced phagocytosis of rings, the early
intraerythrocytic form of the parasite, as an alternative explanation
for protection in G6PD deficiency. We show here that P falciparum
developed similarly in normal RBCs and in sickle trait, beta- and alpha-thalassemia
trait, and HbH RBCs. We also show that membrane-bound hemichromes,
autologous immunoglobulin G (IgG) and complement C3c fragments, aggregated
band 3, and phagocytosis by human monocytes were remarkably higher in
rings developing in all mutant RBCs considered except alpha-thalassemia
trait. Phagocytosis of ring-parasitized mutant RBCs was predominantly
complement mediated and very similar to phagocytosis of senescent or
damaged normal RBCs. Trophozoite-parasitized normal and mutant RBCs were
phagocytosed similarly in all conditions examined. Enhanced phagocytosis
of ring-parasitized mutant RBCs may represent the common mechanism for
malaria protection in nonimmune individuals affected by widespread RBC
mutations, while individuals with alpha-thalassemia trait are likely
protected by a different mechanism. |
6. |
Crabb BS, Cooke BM. Molecular approaches to
malaria: MAM 2004 and beyond. : Trends
Parasitol. 2004 Dec;20(12):547. This
special issue of Trends in Parasitology comprises a collection of timely
reviews arising from the 2nd Molecular Approaches to Malaria meeting
held 1-5 February 2004 in Lorne, Australia, four years after the
successful inaugural meeting. As the name suggests, Molecular Approaches
to Malaria focused on the latest molecular developments in malaria
research, and their biological and clinical implications. By no means is
this special issue intended to represent a comprehensive recapitulation
of all of the presentations at the meeting. Rather, the articles
address, in more general terms, recent advances on broader themes that
were prominent at Molecular Approaches to Malaria meeting 2004 |
Diagnosis, Diagnostics, Immunodiagnosis & Immunodiagnostics: |
11550.
Abegunde
AT. Monkey malaria in man. Lancet. 2004 Oct 2;364(9441):1217. 11551.
Adam I, Ali DA, Alwaseila A,
Kheir MM, Elbashir MI. Mefloquine in the treatment of falciparum malaria
during pregnancy in Eastern Sudan. Saudi Med J. 2004 Oct;25(10):1400-2. 11552.
Amexo
M, Tolhurst R, Barnish G, Bates I. Malaria misdiagnosis: effects on the
poor and vulnerable. Lancet. 2004 Nov 20;364(9448):1896-8. 11553.
Attaran
A. Rescuing malaria treatment, or not? Lancet. 2004 Nov
27;364(9449):1922-3. 11554.
Bharat Bhushan. Measurement of blood
glucose level at the time of admission in severe and complicated
malaria. Indian Med J 2003, 97 (60): 158-9. 11555.
Bhattarai
A, Maini-Thapar M, Ali AS, Bjorkman A. Amodiaquine during pregnancy.
Lancet Infect Dis. 2004 Dec;4(12):721-2; discussion 722. 11556.
Challis
K, Osman NB, Cotiro M, Nordahl G, Dgedge M, Bergstrom S. Impact of a
double dose of sulphadoxine-pyrimethamine to reduce prevalence of
pregnancy malaria in southern Mozambique. Trop Med Int Health. 2004
Oct;9(10):1066-73. 11557.
Chayani
N, Das B, Sur M, Bajoria S. Comparison of Parasite lactate dehydrogenase
based immunochromatographic antigen detection assay (optimal) with
microscopy for detection of
malaria
parasites. Indian Journal of Medical Microbiology. 2004 Apr; 22(2):
104-106. 11558.
Demirev
PA. Mass spectrometry for malaria diagnosis. Expert Rev Mol Diagn. 2004
Nov;4(6):821-9. Review. 11559.
Ganesh K N, Urmila J, Vijayan V A.
Pyrethroid susceptibility & enzyme activity in two malaria vectors,
Anoheles stephensi (Liston). Indian J med Res 2003, 117 (Jan), 30-8. 11560.
Mackintosh
CL, Beeson JG, Marsh K. Clinical features and pathogenesis of severe
malaria. Trends Parasitol. 2004 Dec;20(12):597-603. Review. 11561.
Menendez
C, Schellenberg D, Quinto L, Kahigwa E, Alvarez L, Aponte JJ, Alonso PL.
The effects of short-term iron supplementation on iron status in
infants in malaria-endemic areas. Am J Trop Med Hyg. 2004
Oct;71(4):434-40. 11562.
Nsungwa-Sabiiti
J, Kallander K, Nsabagasani X, Namusisi K, Pariyo G, Johansson A, Tomson
G, Peterson S. Local fever illness classifications: implications for
home management of malaria strategies. Trop Med Int Health. 2004
Nov;9(11):1191-9. 11563.
Okeke
IN. Stopping the spread of drug-resistant malaria. Science. 2004 Dec
17;306(5704):2039-40; author reply 2039-40. 11564.
Orduna
TA. Mapping malaria. CMAJ. 2004 Oct 26;171(9):1023; author reply 1023-4.
11565.
Owusu-Ofori
A, Agbenyega T, Ansong D, Scheld WM. Routine lumbar puncture in children
with febrile seizures in Ghana: should it continue? Int J Infect Dis.
2004 Nov;8(6):353-61. 11566.
Ozsoy
MF, Oncul O, Pekkafali Z, Pahsa A, Yenen OS. Splenic complications in
malaria: report of two cases from Turkey. J Med Microbiol. 2004
Dec;53(Pt 12):1255-8. Review. 11567.
Pamba
A, Maitland K. Capillary refill: prognostic value in Kenyan children.
Arch Dis Child. 2004 Oct;89(10):950-5. 11568.
Pavithra
SR, Banumathy G, Joy O, Singh V, Tatu U. Recurrent fever promotes
Plasmodium falciparum development in human erythrocytes. J Biol Chem.
2004 Nov 5;279(45):46692-9. 11569.
Pilkington
H, Mayombo J, Aubouy N, Deloron P. Malaria, from natural to
supernatural: a qualitative study of mothers' reactions to fever (Dienga,
Gabon). J Epidemiol Community Health. 2004 Oct;58(10):826-30. 11570.
Ravi
Kumar K, Sudarshan KS. Clinical evaluation of a rapid diagnostic kit (Paracheck-Pf)
for
diagnosis of plasmodium falciparum in Karnataka
state of India. Indian
Journal of Preventive and Social Medicine. 2004 Jan-Jun; 35(1 and 2):
10-14. 11571.
Richter
J, de Bernardis C, Sagir A, Walter S, Savalli E, Haussinger D. Is
ultrasound a useful adjunct for assessing malaria patients? Parasitol
Res. 2004 Nov;94(5):349-53. 11572.
Richter
J, Gobels K, Muller-Stover I, Hoppenheit B, Haussinger D. Co-reactivity
of plasmodial histidine-rich protein 2 and aldolase on a combined
immuno-chromographic-malaria dipstick (ICT) as a potential
semi-quantitative marker of high Plasmodium falciparum parasitaemia.
Parasitol Res. 2004 Nov;94(5):384-5. 11573.
Rwagacondo
CE, Karema C, Mugisha V, Erhart A, Dujardin JC, Van Overmeir C, Ringwald
P, D'Alessandro U. Is amodiaquine failing in Rwanda? Efficacy of
amodiaquine alone and combined with artesunate in children with
uncomplicated malaria. Trop Med Int Health. 2004 Oct;9(10):1091-8. 11574.
Schellenberg
D, Kahigwa E, Sanz S, Aponte JJ, Mshinda H, Alonso P, Menendez C. A
randomized comparison of two anemia treatment regimens in Tanzanian
children. Am J Trop Med Hyg. 2004 Oct;71(4):428-33. 11575.
Smithuis
F, Shahmanesh M, Kyaw MK, Savran O, Lwin S, White NJ. Comparison of
chloroquine, sulfadoxine/pyrimethamine, mefloquine and
mefloquine-artesunate for the treatment of falciparum malaria in Kachin
State, North Myanmar. Trop Med Int Health. 2004 Nov;9(11):1184-90. 11576.
Stepniewska
K, Taylor WR, Mayxay M, Price R, Smithuis F, Guthmann JP, Barnes K,
Myint HY, Adjuik M, Olliaro P, Pukrittayakamee S, Looareesuwan S, Hien
TT, Farrar J, Nosten F, Day NP, White NJ.
In vivo assessment of drug efficacy against Plasmodium falciparum
malaria: duration of follow-up. Antimicrob Agents Chemother. 2004
Nov;48(11):4271-80. 11577.
Vokaer
M, Bier JC, David P, Grand S, Supiot F, Ventura M, Bartholome EJ.
Striatal lesions: an underestimated complication of cerebral malaria?
Eur J Neurol. 2004 Oct;11(10):715-6. 11578.
Vreugdenhil
CJ, Scheper FY, Hoogstraatte SR, Smolders M, Gikunda S, Cobelens FG,
Kager PA. Comparison of the parasitologic efficacy of amodiaquine and
sulfadoxine-pyrimethamine in the treatment of Plasmodium falciparum
malaria in the Bungoma District of western Kenya. Am J Trop Med Hyg.
2004 Nov;71(5):537-41. 11579.
Walsh
DS, Eamsila C, Sasiprapha T, Sangkharomya S, Khaewsathien P, Supakalin
P, Tang DB, Jarasrumgsichol P, Cherdchu C, Edstein MD, Rieckmann KH,
Brewer TG. Efficacy
of monthly tafenoquine for prophylaxis of Plasmodium vivax and
multidrug-resistant P. falciparum malaria. J Infect Dis. 2004 Oct
15;190(8):1456-63. 11580. Willcox ML, Bodeker G. Traditional herbal medicines for malaria. BMJ. 2004 Nov 13;329(7475):1156-9. Review. 11581. Williams HA, Durrheim D, Shretta R. The process of changing national malaria treatment policy: lessons from country-level studies. Health Policy Plan. 2004 Nov;19(6):356-70. Review. |
Pathogenesis: |
11582.
Ayi
K, Turrini F, Piga A, Arese P. Enhanced phagocytosis of ring-parasitized
mutant erythrocytes: a common mechanism that may explain protection
against falciparum malaria in sickle trait and beta-thalassemia trait.
Blood. 2004 Nov 15;104(10):3364-71. 11583.
Baird
JK. Chloroquine resistance in Plasmodium vivax. Antimicrob Agents
Chemother. 2004 Nov;48(11):4075-83. Review. 11584.
Becker
K, Kirk K. Of malaria, metabolism and membrane transport. Trends
Parasitol. 2004 Dec;20(12):590-6. Review. 11585.
Blackman
MJ. Proteases in host cell invasion by the malaria parasite. Cell
Microbiol. 2004 Oct;6(10):893-903. Review. 11586.
Borrmann
S, Issifou S, Esser G, Adegnika AA, Ramharter M, Matsiegui PB,
Oyakhirome S, Mawili-Mboumba DP, Missinou MA, Kun JF, Jomaa H, Kremsner
PG. Fosmidomycin-clindamycin for the treatment of Plasmodium falciparum
malaria. J Infect Dis. 2004 Nov 1;190(9):1534-40. 11587.
Cooke
BM, Coppel RL. Blue skies or stormy weather: what lies ahead for malaria
research? Trends Parasitol. 2004 Dec;20(12):611-4. Review. 11588.
Cooke
BM, Lingelbach K, Bannister LH, Tilley L. Protein trafficking in
Plasmodium falciparum-infected red blood cells. Trends Parasitol. 2004
Dec;20(12):581-9. Review. 11589.
Coppel
RL, Roos DS, Bozdech Z. The genomics of malaria infection. Trends
Parasitol. 2004 Dec;20(12):553-7. Review. 11590.
Crabb
BS, Cooke BM. Molecular approaches to malaria: MAM 2004 and beyond.
Trends Parasitol. 2004 Dec;20(12):547. 11591.
Craig
MH, Kleinschmidt I, Le Sueur D, Sharp BL. Exploring 30 years of malaria
case data in KwaZulu-Natal, South Africa: part II. The impact of
non-climatic factors. Trop Med Int Health. 2004 Dec;9(12):1258-66. 11592.
Deitsch
KW, Hviid L. Variant surface antigens, virulence genes and the
pathogenesis of malaria. Trends Parasitol. 2004 Dec;20(12):562-6.
Review. 11593.
Dodd
RY. Current safety of the blood supply in the United States. Int J
Hematol. 2004 Nov;80(4):301-5. Review. 11594.
Dorsey
G, Gasasira AF, Machekano R, Kamya MR, Staedke SG, Hubbard A. The impact
of age, temperature, and parasite density on treatment outcomes from
antimalarial clinical trials in Kampala, Uganda. Am J Trop Med Hyg. 2004
Nov;71(5):531-6. 11595.
Ehrhardt
S, Wichmann D, Hemmer CJ, Burchard GD, Brattig NW. Circulating
concentrations of cardiac proteins in complicated and uncomplicated
Plasmodium falciparum malaria. Trop Med Int Health. 2004
Oct;9(10):1099-103. 11596.
Eipe
N. Malaria and postoperative fever. Acta Anaesthesiol Scand. 2004
Oct;48(9):1217. 11597.
Gatton
ML, Cheng Q. Modeling the development of acquired clinical immunity to
Plasmodium falciparum malaria. Infect Immun. 2004 Nov;72(11):6538-45. 11598.
Guyatt
HL, Snow RW. Impact of malaria during pregnancy on low birth weight in
sub-Saharan Africa. Clin Microbiol Rev. 2004 Oct;17(4):760-9. 11599.
Hallett
RL, Sutherland CJ, Alexander N, Ord R, Jawara M, Drakeley CJ, Pinder M,
Walraven G, Targett GA, Alloueche A. Combination therapy counteracts the
enhanced transmission of drug-resistant malaria parasites to mosquitoes.
Antimicrob Agents Chemother. 2004 Oct;48(10):3940-3. 11600.
Hampton
T. Malaria vaccine shows promise. JAMA. 2004 Dec 8;292(22):2703-4. 11601.
Khan
SM, Waters AP. Malaria parasite transmission stages: an update. Trends
Parasitol. 2004 Dec;20(12):575-80. Review. 11602.
Mebrahtu
T, Stoltzfus RJ, Chwaya HM, Jape JK, Savioli L, Montresor A, Albonico M,
Tielsch JM. Low-dose daily iron supplementation for 12 months does not
increase the prevalence of malarial infection or density of parasites in
young Zanzibari children. J Nutr. 2004 Nov;134(11):3037-41. 11603.
Mockenhaupt
FP, Ehrhardt S, Gellert S, Otchwemah RN, Dietz E, Anemana SD, Bienzle U.
Alpha(+)-thalassemia protects African children from severe malaria.
Blood. 2004 Oct 1;104(7):2003-6. 11604.
Newman
RD, Parise ME, Barber AM, Steketee RW. Malaria-related deaths among U.S.
travelers, 1963-2001. Ann Intern Med. 2004
Oct 5;141(7):547-55. Review. 11605.
Rich
SM. The unpredictable past of Plasmodium vivax revealed in its genome.
Proc Natl Acad Sci U S A. 2004 Nov 2;101(44):15547-8. 11606.
Schapira
A. DDT still has a role in the fight against malaria. Nature. 2004 Nov
25;432(7016):439. 11607.
Sharma
SK, Chattopadhyay R, Chakrabarti K, Pati SS, Srivastava VK, Tyagi PK,
Mahanty S, Misra SK, Adak T, Das BS, Chitnis CE. Epidemiology of malaria
transmission and development of natural immunity in a malaria-endemic
village, San Dulakudar, in Orissa state, India. Am J Trop Med Hyg. 2004
Oct;71(4):457-65. 11608.
Smith
JD, Deitsch KW. Pregnancy-associated malaria and the prospects for
syndrome-specific antimalaria vaccines. J Exp Med. 2004 Nov
1;200(9):1093-7. 11609.
Tarantola
AP, Rachline AC, Konto C, Houze S, Lariven S, Fichelle A, Ammar D,
Sabah-Mondan C, Vrillon H, Bouchaud O, Pitard F, Bouvet E; Group d'Etude
des Risques d'Exposition des Soignants aux agents infectieux.
Occupational malaria following needlestick injury. Emerg Infect Dis.
2004 Oct;10(10):1878-80 11610.
Vernick
KD, Waters AP. Genomics and malaria control. N Engl J Med. 2004 Oct
28;351(18):1901-4. Review. 11611.
Yuda M, Ishino T. Liver invasion
by malarial parasites--how do malarial parasites break through the host
barrier? Cell Microbiol. 2004 Dec;6(12):1119-25. Review. |
Vaccines: |
11612.
Van
de Perre P, Dedet JP. Vaccine efficacy: winning a battle (not war)
against malaria. Lancet. 2004 Oct 16;364(9443):1380-3. |
Therapy: |
11613.
Bhatnagar
S, Natchu UC. Zinc in child health and disease. Indian J Pediatr. 2004
Nov;71(11):991-5. Review. 11614.
Bradbury
J. Synthetic antimalaria drug enters clinical trials. Lancet Infect Dis.
2004 Oct;4(10):598. 11615.
Cyranoski
D. Campaign to fight malaria hit by surge in demand for medicine.
Nature. 2004 Nov 18;432(7015):259. 11616.
Dondorp
AM, Newton PN, Mayxay M, Van Damme W, Smithuis FM, Yeung S, Petit A,
Lynam AJ, Johnson A, Hien TT, McGready R, Farrar JJ, Looareesuwan S, Day
NP, Green MD, White NJ. Fake antimalarials in Southeast Asia are a major
impediment to malaria control: multinational cross-sectional survey on
the prevalence of fake antimalarials. Trop Med Int Health. 2004
Dec;9(12):1241-6. 11617.
Duong
S, Lim P, Fandeur T, Tsuyuoka R, Wongsrichanalai C. Importance of
protection of antimalarial combination therapies. Lancet. 2004 Nov
13;364(9447):1754-5. 11618.
Goklany
IM. Climate change and malaria. Science. 2004 Oct 1;306(5693):55-7;
author reply 55-7. 11619.
Graham
K. New tools to control malaria in refugee camps. J R Soc Health. 2004
Nov;124(6):253-5. 11620.
Haynes
RK, Krishna S. Artemisinins: activities and actions. Microbes Infect.
2004 Nov;6(14):1339-46. Review. 11621.
Hien
TT, Davis TM, Chuong LV, Ilett KF, Sinh DX, Phu NH, Agus C, Chiswell GM,
White NJ, Farrar J. Comparative pharmacokinetics of intramuscular
artesunate and artemether in patients with severe falciparum malaria.
Antimicrob Agents Chemother. 2004 Nov;48(11):4234-9. 11622.
Korenromp
EL, Armstrong-Schellenberg JR, Williams BG, Nahlen BL, Snow RW. Impact
of malaria control on childhood anaemia in Africa -- a quantitative
review. Trop Med Int Health. 2004 Oct;9(10):1050-65. Review. 11623.
Maitland
K, Makanga M, Williams TN. Falciparum malaria: current therapeutic
challenges. Curr Opin Infect Dis. 2004 Oct;17(5):405-12. Review. 11624.
Meyer
CG, Marks F, May J. Editorial: Gin tonic revisited. Trop Med Int Health.
2004 Dec;9(12):1239-40. 11625.
Nathan
R, Masanja H, Mshinda H, Schellenberg JA, de Savigny D, Lengeler C,
Tanner M, Victora CG. Mosquito nets and the poor: can social marketing
redress inequities in access? Trop Med Int Health. 2004
Oct;9(10):1121-6. 11626.
Noor
N, Rattani A. Chlorproguanil-dapsone for malaria. Lancet. 2004 Nov
13;364(9447):1753-4. 11627.
Pussard
E, Straczek C, Kabore I, Bicaba A, Balima-Koussoube T, Bouree P,
Barennes H. Dose-dependent resorption of quinine after intrarectal
administration to children with moderate Plasmodium falciparum malaria.
Antimicrob Agents Chemother. 2004 Nov;48(11):4422-6. 11628.
Standing
JF, Wong IC. Chlorproguanil-dapsone for malaria. Lancet. 2004 Nov
13;364(9447):1752-3; author reply 1753. 11629.
Yasir
M, Mahmood A. Quinine based combination therapy (QCT): first choice! J
Coll Physicians Surg Pak. 2004 Oct;14(10):643. |